-
1
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL- 18-mediated function
-
DOI 10.1016/S1074-7613(00)80596-8
-
O. Adachi, T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, and M. Sakagami et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function Immunity 9 1998 143 150 (Pubitemid 28361303)
-
(1998)
Immunity
, vol.9
, Issue.1
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Tsutsui, H.5
Sakagami, M.6
Nakanishi, K.7
Akira, S.8
-
2
-
-
62149144052
-
Allergic bronchopulmonary aspergillosis
-
R. Agarwal Allergic bronchopulmonary aspergillosis Chest 135 2009 805 826
-
(2009)
Chest
, vol.135
, pp. 805-826
-
-
Agarwal, R.1
-
3
-
-
0027381406
-
The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation
-
M. Aoki, F. Hamada, T. Sugimoto, S. Sumida, T. Akiyama, and K. Toyoshima The human COT protooncogene encodes 2 protein-serine threonine kinase with different transforming activities by alternative initiation of translation Journal of Biological Chemistry 268 1993 22723 22732 (Pubitemid 23318331)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.30
, pp. 22723-22732
-
-
Aoki, M.1
Hamada, F.2
Sugimoto, T.3
Sumida, S.4
Akiyama, T.5
Toyoshima, K.6
-
4
-
-
33644761875
-
Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells
-
DOI 10.1073/pnas.0511113103
-
A. Banerjee, R. Gugasyan, M. McMahon, and S. Gerondakis Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells Proceedings of the National Academy of Sciences of the United States of America 103 2006 3274 3279 (Pubitemid 43346460)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.9
, pp. 3274-3279
-
-
Banerjee, A.1
Gugasyan, R.2
McMahon, M.3
Gerondakis, S.4
-
5
-
-
84876531002
-
The level of p38 alpha mitogen-activated protein kinase activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa
-
T. Beaudoin, S. LaFayette, L. Roussel, J. Berube, M. Desrosiers, and N. Dao et al. The level of p38 alpha mitogen-activated protein kinase activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa Journal of Infectious Diseases 207 2013 1544 1555
-
(2013)
Journal of Infectious Diseases
, vol.207
, pp. 1544-1555
-
-
Beaudoin, T.1
Lafayette, S.2
Roussel, L.3
Berube, J.4
Desrosiers, M.5
Dao, N.6
-
6
-
-
1442325340
-
Cytokine secretion by cystic fibrosis airway epithelial cells
-
M.N. Becker, M.S. Sauer, M.S. Muhlebach, A.J. Hirsh, Q. Wu, and M.W. Verghese et al. Cytokine secretion by cystic fibrosis airway epithelial cells American Journal of Respiratory and Critical Care Medicine 169 2004 645 653 (Pubitemid 38270902)
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.169
, Issue.5
, pp. 645-653
-
-
Becker, M.N.1
Sauer, M.S.2
Muhlebach, M.S.3
Hirsh, A.J.4
Wu, Q.5
Verghese, M.W.6
Randell, S.H.7
-
7
-
-
0038112098
-
NF-B1 p105 negatively regulates TPL-2 MEK kinase activity
-
DOI 10.1128/MCB.23.14.4739-4752.2003
-
S. Beinke, J. Deka, V. Lang, M.P. Belich, P.A. Walker, and S. Howell et al. NF-kappa B1 p105 negatively regulates TPL-2 MEK kinase activity Molecular and Cellular Biology 23 2003 4739 4752 (Pubitemid 36793322)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.14
, pp. 4739-4752
-
-
Beinke, S.1
Deka, J.2
Lang, V.3
Belich, M.P.4
Walker, P.A.5
Howell, S.6
Smerdon, S.J.7
Gamblin, S.J.8
Ley, S.C.9
-
8
-
-
6344264987
-
Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IB kinase-induced proteolysis of NF-B1 p105
-
DOI 10.1128/MCB.24.21.9658-9667.2004
-
S. Beinke, M.J. Robinson, M. Hugunin, and S.C. Ley Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by I kappa B kinase-induced proteolysis of NF-kappa B1 p105 Molecular and Cellular Biology 24 2004 9658 9667 (Pubitemid 39391700)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.21
, pp. 9658-9667
-
-
Beinke, S.1
Robinson, M.J.2
Hugunin, M.3
Ley, S.C.4
-
9
-
-
0033611544
-
TPL-2 kinase regulates the proteolysis of the NF-kappa B-inhibitory protein NF-kappa B1 p105
-
M.P. Belich, A. Salmeron, L.H. Johnston, and S.C. Ley TPL-2 kinase regulates the proteolysis of the NF-kappa B-inhibitory protein NF-kappa B1 p105 Nature 397 1999 363 368
-
(1999)
Nature
, vol.397
, pp. 363-368
-
-
Belich, M.P.1
Salmeron, A.2
Johnston, L.H.3
Ley, S.C.4
-
10
-
-
77954603744
-
Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa
-
J. Berube, L. Roussel, L. Nattagh, and S. Rousseau Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa Journal of Biological Chemistry 285 2010 22299 22307
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 22299-22307
-
-
Berube, J.1
Roussel, L.2
Nattagh, L.3
Rousseau, S.4
-
11
-
-
34250891982
-
Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer
-
DOI 10.1021/pr0700293
-
T.M. Black, C.L. Andrews, G. Kilili, M. Ivan, P.N. Tsichlis, and P. Vouros Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer Journal of Proteome Research 6 2007 2269 2276 (Pubitemid 46985114)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.6
, pp. 2269-2276
-
-
Black, T.M.1
Andrews, C.L.2
Kilili, G.3
Ivan, M.4
Tsichlis, P.N.5
Vouros, P.6
-
12
-
-
0030902506
-
Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation
-
J.D. Ceci, C.P. Patriotis, C. Tsatsanis, A.M. Makris, R. Kovatch, and D.A. Swing et al. Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation Genes & Development 11 1997 688 700 (Pubitemid 27157158)
-
(1997)
Genes and Development
, vol.11
, Issue.6
, pp. 688-700
-
-
Ceci, J.D.1
Patriotis, C.P.2
Tsatsanis, C.3
Makris, A.M.4
Kovatch, R.5
Swing, D.A.6
Jenkins, N.A.7
Tsichlis, P.N.8
Copeland, N.G.9
-
14
-
-
17744371331
-
TNF- induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
-
DOI 10.1016/S0092-8674(00)00210-5
-
C.D. Dumitru, J.D. Ceci, C. Tsatsanis, D. Kontoyiannis, K. Stamatakis, and J.H. Lin et al. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway Cell 103 2000 1071 1083 (Pubitemid 32040907)
-
(2000)
Cell
, vol.103
, Issue.7
, pp. 1071-1083
-
-
Dumitru, C.D.1
Ceci, J.D.2
Tsatsanis, C.3
Kontoyiannis, D.4
Stamatakis, K.5
Lin, J.-H.6
Patriotis, C.7
Jenkins, N.A.8
Copeland, N.G.9
Kollias, G.10
Tsichlis, P.N.11
-
15
-
-
0035431701
-
Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the tnf-r/nfb pathway
-
O. Eidelman, M. Srivastava, J. Zhang, X. Leighton, J. Murtie, and C. Jozwik et al. Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alpha R/NF kappa B pathway Molecular Medicine 7 2001 523 534 (Pubitemid 33701958)
-
(2001)
Molecular Medicine
, vol.7
, Issue.8
, pp. 523-534
-
-
Eidelman, O.1
Srivastava, M.2
Zhang, J.3
Leighton, X.4
Murtie, J.5
Jozwik, C.6
Jacobson, K.7
Weinstein, D.L.8
Metcalf, E.L.9
Pollard, H.B.10
-
16
-
-
0028969594
-
A multicenter study of alternate-day prednisone therapy in patients with cystic fibrosis. Cystic Fibrosis Foundation Prednisone Trial Group
-
H. Eigen, B.J. Rosenstein, S. FitzSimmons, and D.V. Schidlow A multicenter study of alternate-day prednisone therapy in patients with cystic fibrosis. Cystic Fibrosis Foundation Prednisone Trial Group Journal of Pediatrics 126 1995 515 523
-
(1995)
Journal of Pediatrics
, vol.126
, pp. 515-523
-
-
Eigen, H.1
Rosenstein, B.J.2
Fitzsimmons, S.3
Schidlow, D.V.4
-
17
-
-
0027171138
-
Activation of mitogen-activated protein kinase/extracellular signal- regulated kinase kinase by G protein and tyrosine kinase oncoproteins
-
A.M. Gardner, R.R. Vaillancourt, and G.L. Johnson Activation of mitogen-activated protein kinase extracellular signal-regulated kinase kinase by G-protein and tryrosine kinase oncoproteins Journal of Biological Chemistry 268 1993 17896 17901 (Pubitemid 23260303)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.24
, pp. 17896-17901
-
-
Gardner, A.M.1
Vaillancourt, R.R.2
Johnson, G.L.3
-
18
-
-
80054842204
-
Constitutive intestinal NF-kappa B does not trigger destructive inflammation unless accompanied by MAPK activation
-
M. Guma, D. Stepniak, H. Shaked, M.E. Spehlmann, S. Shenouda, and H. Cheroutre et al. Constitutive intestinal NF-kappa B does not trigger destructive inflammation unless accompanied by MAPK activation Journal of Experimental Medicine 208 2011 1889 1900
-
(2011)
Journal of Experimental Medicine
, vol.208
, pp. 1889-1900
-
-
Guma, M.1
Stepniak, D.2
Shaked, H.3
Spehlmann, M.E.4
Shenouda, S.5
Cheroutre, H.6
-
19
-
-
36348968386
-
Pharmacologic inhibition of Tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood
-
DOI 10.1074/jbc.M703694200
-
J.P. Hall, Y. Kurdi, S. Hsu, J. Cuozzo, J. Liu, and J-B. Telliez et al. Pharmacologic inhibition of Tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood Journal of Biological Chemistry 282 2007 33295 33304 (Pubitemid 350159547)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.46
, pp. 33295-33304
-
-
Hall, J.P.1
Kurdi, Y.2
Hsu, S.3
Cuozzo, J.4
Liu, J.5
Telliez, J.-B.6
Seidl, K.J.7
Winkler, A.8
Hu, Y.9
Green, N.10
Askew, G.R.11
Tam, S.12
Clark, J.D.13
Lin, L.-L.14
-
20
-
-
70350690506
-
IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2
-
H. Handoyo, M.J. Stafford, E. McManus, D. Baltzis, M. Peggie, and P. Cohen IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2 Biochemical Journal 424 2009 109 118
-
(2009)
Biochemical Journal
, vol.424
, pp. 109-118
-
-
Handoyo, H.1
Stafford, M.J.2
McManus, E.3
Baltzis, D.4
Peggie, M.5
Cohen, P.6
-
21
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
T. Kawai, and S. Akira The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors Nature Immunology 11 2010 373 384
-
(2010)
Nature Immunology
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
22
-
-
84881559756
-
Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells
-
S. Kim, B.A. Beyer, C. Lewis, and J.A. Nadel Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells PLoS ONE 8 2013 1 12
-
(2013)
PLoS ONE
, vol.8
, pp. 1-12
-
-
Kim, S.1
Beyer, B.A.2
Lewis, C.3
Nadel, J.A.4
-
23
-
-
34548038663
-
High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial
-
DOI 10.1016/j.jpeds.2007.04.009, PII S0022347607003435
-
L.C. Lands, R. Milner, A.M. Cantin, D. Manson, and M. Corey High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial Journal of Pediatrics 151 2007 249 254 (Pubitemid 47284135)
-
(2007)
Journal of Pediatrics
, vol.151
, Issue.3
, pp. 249-254
-
-
Lands, L.C.1
Milner, R.2
Cantin, A.M.3
Manson, D.4
Corey, M.5
-
24
-
-
2942594766
-
ABIN-2 forms a ternary complex with TPL-2 and NF-B1 p105 and is essential for TPL-2 protein stability
-
DOI 10.1128/MCB.24.12.5235-5248.2004
-
V. Lang, A. Symons, S.J. Watton, J. Janzen, Y. Soneji, and S. Beinke et al. ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability Molecular and Cellular Biology 24 2004 5235 5248 (Pubitemid 38738159)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.12
, pp. 5235-5248
-
-
Lang, V.1
Symons, A.2
Watton, S.J.3
Janzen, J.4
Soneji, Y.5
Beinke, S.6
Howell, S.7
Ley, S.C.8
-
25
-
-
84857222716
-
Genetic and pharmacological targeting of TPL-2 kinase ameliorates experimental colitis: A potential target for the treatment of Crohn's disease
-
M. Lawrenz, A. Visekruna, A. Kuhl, N. Schmidt, S.H.E. Kaufmann, and U. Steinhoff Genetic and pharmacological targeting of TPL-2 kinase ameliorates experimental colitis: a potential target for the treatment of Crohn's disease Mucosal Immunology 5 2012 129 139
-
(2012)
Mucosal Immunology
, vol.5
, pp. 129-139
-
-
Lawrenz, M.1
Visekruna, A.2
Kuhl, A.3
Schmidt, N.4
Kaufmann, S.H.E.5
Steinhoff, U.6
-
27
-
-
0027370827
-
Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro
-
S.G. Macdonald, C.M. Crews, L. Wu, J. Driller, R. Clark, and R.L. Erikson et al. Reconstitution of the Raf-1-MEK-ERK signal-transduction pathway in-vitro Molecular and Cellular Biology 13 1993 6615 6620 (Pubitemid 23321115)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.11
, pp. 6615-6620
-
-
Macdonald, S.G.1
Crews, C.M.2
Wu, L.3
Driller, J.4
Clark, R.5
Erikson, R.L.6
McCormick, F.7
-
28
-
-
0027253823
-
Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: Activation by provirus insertion
-
A. Makris, C. Patriotis, S.E. Bear, and P.N. Tsichlis Genomic organization and expression of TPL-2 in normal-cells and moloney murine leukemia virus-induced rat T-cell lymphomas-activation by provirus insertion Journal of Virology 67 1993 4283 4289 (Pubitemid 23180755)
-
(1993)
Journal of Virology
, vol.67
, Issue.7
, pp. 4283-4289
-
-
Makris, A.1
Patriotis, C.2
Bear, S.E.3
Tsichlis, P.N.4
-
29
-
-
84875108470
-
The protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs)
-
G. Martel, J. Berube, and S. Rousseau The protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs) PLoS ONE 8 2013 1 9
-
(2013)
PLoS ONE
, vol.8
, pp. 1-9
-
-
Martel, G.1
Berube, J.2
Rousseau, S.3
-
30
-
-
84888302197
-
The protein kinases TPL2 and EGFR contribute to ERK1/ERK2 hyper-activation in CFTR Delta F508-expressing airway epithelial cells exposed to Pseudomonas aeruginosa
-
G. Martel, L. Roussel, and S. Rousseau The protein kinases TPL2 and EGFR contribute to ERK1/ERK2 hyper-activation in CFTR Delta F508-expressing airway epithelial cells exposed to Pseudomonas aeruginosa Biochemical and Biophysical Research Communications 441 2013 689 692
-
(2013)
Biochemical and Biophysical Research Communications
, vol.441
, pp. 689-692
-
-
Martel, G.1
Roussel, L.2
Rousseau, S.3
-
31
-
-
21244455537
-
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene- and granulocyte colony-stimulating factor in bronchial epithelium: Implications for airway inflammation in cystic fibrosis
-
F. McAllister, A. Henry, J.L. Kreindler, P.J. Dubin, L. Ulrich, and C. Steele et al. Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-a and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis Journal of Immunology 175 2005 404 412 (Pubitemid 40884344)
-
(2005)
Journal of Immunology
, vol.175
, Issue.1
, pp. 404-412
-
-
McAllister, F.1
Henry, A.2
Kreindler, J.L.3
Dubin, P.J.4
Ulrich, L.5
Steele, C.6
Finder, J.D.7
Pilewski, J.M.8
Carreno, B.M.9
Goldman, S.J.10
Pirhonen, J.11
Kolls, J.K.12
-
32
-
-
34547209343
-
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
-
DOI 10.1016/j.bbamcr.2006.10.001, PII S0167488906003156
-
J.A. McCubrey, L.S. Steelman, W.H. Chappell, S.L. Abrams, E.W.T. Wong, and F. Chang et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance Biochimica et Biophysica Acta - Molecular Cell Research 1773 2007 1263 1284 (Pubitemid 47125967)
-
(2007)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1773
, Issue.8
, pp. 1263-1284
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
Abrams, S.L.4
Wong, E.W.T.5
Chang, F.6
Lehmann, B.7
Terrian, D.M.8
Milella, M.9
Tafuri, A.10
Stivala, F.11
Libra, M.12
Basecke, J.13
Evangelisti, C.14
Martelli, A.M.15
Franklin, R.A.16
-
33
-
-
0025778893
-
Structure and transforming potential of the human cot oncogene encoding a putative protein kinase
-
J. Miyoshi, T. Higashi, H. Mukai, T. Ohuchi, and T. Kakunaga Structure and transforming potential of the human COT oncogene encoding a putative protein-kinase Molecular and Cellular Biology 11 1991 4088 4096 (Pubitemid 21895798)
-
(1991)
Molecular and Cellular Biology
, vol.11
, Issue.8
, pp. 4088-4096
-
-
Miyoshi, J.1
Higashi, T.2
Mukai, H.3
Ohuchi, T.4
Kakunaga, T.5
-
34
-
-
69549089991
-
Cystic fibrosis-related diabetes: Current trends in prevalence, incidence, and mortality
-
A. Moran, J. Dunitz, B. Nathan, A. Saeed, B. Holme, and W. Thomas Cystic fibrosis-related diabetes: current trends in prevalence, incidence, and mortality Diabetes Care 32 2009 1626 1631
-
(2009)
Diabetes Care
, vol.32
, pp. 1626-1631
-
-
Moran, A.1
Dunitz, J.2
Nathan, B.3
Saeed, A.4
Holme, B.5
Thomas, W.6
-
35
-
-
58149215722
-
Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders
-
S.M. Moskowitz, J.F. Chmiel, D.L. Sternen, E. Cheng, R.L. Gibson, and S.G. Marshall et al. Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders Genetics in Medicine 10 2008 851 868
-
(2008)
Genetics in Medicine
, vol.10
, pp. 851-868
-
-
Moskowitz, S.M.1
Chmiel, J.F.2
Sternen, D.L.3
Cheng, E.4
Gibson, R.L.5
Marshall, S.G.6
-
36
-
-
84875996333
-
Essential roles of K63-linked polyubiquitin-binding proteins TAB2 and TAB3 in B cell activation via MAPKs
-
D. Ori, H. Kato, H. Sanjo, S. Tartey, T. Mino, and S. Akira et al. Essential roles of K63-linked polyubiquitin-binding proteins TAB2 and TAB3 in B cell activation via MAPKs Journal of Immunology 190 2013 4037 4045
-
(2013)
Journal of Immunology
, vol.190
, pp. 4037-4045
-
-
Ori, D.1
Kato, H.2
Sanjo, H.3
Tartey, S.4
Mino, T.5
Akira, S.6
-
37
-
-
79958086613
-
Interleukin-33 biology with potential insights into human diseases
-
G. Palmer, and C. Gabay Interleukin-33 biology with potential insights into human diseases Nature Reviews Rheumatology 7 2011 321 329
-
(2011)
Nature Reviews Rheumatology
, vol.7
, pp. 321-329
-
-
Palmer, G.1
Gabay, C.2
-
38
-
-
0027447467
-
Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation
-
C. Patriotis, A. Makris, S.E. Bear, and P.N. Tsichlis Tumor progression locus-2 (TPL-2) encodes a protein-kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation Proceedings of the National Academy of Sciences of the United States of America 90 1993 2251 2255 (Pubitemid 23078604)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.6
, pp. 2251-2255
-
-
Patriotis, C.1
Makris, A.2
Bear, S.E.3
Tsichlis, P.N.4
-
39
-
-
79953227706
-
Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance
-
J.W. Perfield, Y. Lee, G.I. Shulman, V.T. Samuel, M.J. Jurczak, and E. Chang et al. Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance Diabetes 60 2011 1168 1176
-
(2011)
Diabetes
, vol.60
, pp. 1168-1176
-
-
Perfield, J.W.1
Lee, Y.2
Shulman, G.I.3
Samuel, V.T.4
Jurczak, M.J.5
Chang, E.6
-
40
-
-
84874488611
-
Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor induced TIMP-1 gene transcription in hepatic stellate cells in mice
-
M.J. Perugorria, L.B. Murphy, N. Fullard, J.B. Chakraborty, D. Vyrla, and C.L. Wilson et al. Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor induced TIMP-1 gene transcription in hepatic stellate cells in mice Hepatology 57 2013 1238 1249
-
(2013)
Hepatology
, vol.57
, pp. 1238-1249
-
-
Perugorria, M.J.1
Murphy, L.B.2
Fullard, N.3
Chakraborty, J.B.4
Vyrla, D.5
Wilson, C.L.6
-
41
-
-
67651109020
-
Pathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis: Current understanding and future directions
-
R.R. Rapaka, and J.K. Kolls Pathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis: current understanding and future directions Medical Mycology 47 2009 S331 S337
-
(2009)
Medical Mycology
, vol.47
-
-
Rapaka, R.R.1
Kolls, J.K.2
-
42
-
-
35649024803
-
Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages
-
DOI 10.1128/MCB.00301-07
-
M.J. Robinson, S. Beinke, A. Kouroumalis, P.N. Tsichlis, and S.C. Ley Phophorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages Molecular and Cellular Biology 27 2007 7355 7364 (Pubitemid 350033644)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.21
, pp. 7355-7364
-
-
Robinson, M.J.1
Beinke, S.2
Kouroumalis, A.3
Tsichlis, P.N.4
Ley, S.C.5
-
43
-
-
38949132532
-
TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF in LPS-stimulated macrophages
-
DOI 10.1242/jcs.018671
-
S. Rousseau, M. Papoutsopoulou, A. Symons, D. Cook, J.M. Lucocq, and A.R. Prescott et al. TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages Journal of Cell Science 121 2008 149 154 (Pubitemid 351228446)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.2
, pp. 149-154
-
-
Rousseau, S.1
Papoutsopoulou, M.2
Symons, A.3
Cook, D.4
Lucocq, J.M.5
Prescott, A.R.6
O'Garra, A.7
Ley, S.C.8
Cohen, P.9
-
44
-
-
84875227872
-
IL-33 is expressed in epithelia from patients with cystic fibrosis and potentiates neutrophil recruitment
-
L. Roussel, R. Farias, and S. Rousseau IL-33 is expressed in epithelia from patients with cystic fibrosis and potentiates neutrophil recruitment Journal of Allergy and Clinical Immunology 131 2013 913 916
-
(2013)
Journal of Allergy and Clinical Immunology
, vol.131
, pp. 913-916
-
-
Roussel, L.1
Farias, R.2
Rousseau, S.3
-
45
-
-
79952454406
-
P. Aeruginosa drives cxcl8 synthesis via redundant toll-like receptors and nadph oxidase in cftr delta f508 airway epithelial cells
-
L. Roussel, G. Martel, J. Berube, and S. Rousseau P. aeruginosa drives CXCL8 synthesis via redundant toll-like receptors and NADPH oxidase in CFTR Delta F508 airway epithelial cells Journal of Cystic Fibrosis 10 2011 107 113
-
(2011)
Journal of Cystic Fibrosis
, vol.10
, pp. 107-113
-
-
Roussel, L.1
Martel, G.2
Berube, J.3
Rousseau, S.4
-
47
-
-
84878241823
-
Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2
-
C. Sanz-Garcia, G. Ferrer-Mayorga, A. Gonzalez-Rodriguez, A.M. Valverde, A. Martin-Duce, and J.P. Velasco-Martin et al. Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2 Journal of Biological Chemistry 288 2013 15342 15351
-
(2013)
Journal of Biological Chemistry
, vol.288
, pp. 15342-15351
-
-
Sanz-Garcia, C.1
Ferrer-Mayorga, G.2
Gonzalez-Rodriguez, A.3
Valverde, A.M.4
Martin-Duce, A.5
Velasco-Martin, J.P.6
-
48
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
DOI 10.1038/ni1255, PII N1255
-
S. Sato, H. Sanjo, K. Takeda, J. Ninomiya-Tsuji, M. Yamamoto, and T. Kawai et al. Essential function for the kinase TAK1 in innate and adaptive immune responses Nature Immunology 6 2005 1087 1095 (Pubitemid 41541786)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1087-1095
-
-
Sato, S.1
Sanjo, H.2
Takeda, K.3
Ninomiya-Tsuji, J.4
Yamamoto, M.5
Kawai, T.6
Matsumoto, K.7
Takeuchi, O.8
Akira, S.9
-
49
-
-
17844377960
-
Inflammation in cystic fibrosis airways: Relationship to increased bacterial adherence
-
DOI 10.1183/09031936.01.17100270
-
P. Scheid, L. Kempster, U. Griesenbach, J.C. Davies, A. Dewar, and P.P. Weber et al. Inflammation in cystic fibrosis airways: relationship to increased bacterial adherence European Respiratory Journal 17 2001 27 35 (Pubitemid 32600552)
-
(2001)
European Respiratory Journal
, vol.17
, Issue.1
, pp. 27-35
-
-
Scheid, P.1
Kempster, L.2
Griesenbach, U.3
Davies, J.C.4
Dewar, A.5
Weber, P.P.6
Colledge, W.H.7
Evans, M.J.8
Geddes, D.M.9
Alton, E.W.F.W.10
-
51
-
-
33745382457
-
Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62
-
DOI 10.1016/j.febslet.2006.06.004, PII S001457930600706X
-
M.J. Stafford, N.A. Morrice, M.W. Peggie, and P. Cohen Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62 FEBS Letters 580 2006 4010 4014 (Pubitemid 43946869)
-
(2006)
FEBS Letters
, vol.580
, Issue.16
, pp. 4010-4014
-
-
Stafford, M.J.1
Morrice, N.A.2
Peggie, M.W.3
Cohen, P.4
-
52
-
-
9644301015
-
A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation
-
DOI 10.1172/JCI200420014
-
K. Sugimoto, M. Ohata, J. Miyoshi, H. Ishizaki, N. Tsuboi, and A. Masuda et al. A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation Journal of Clinical Investigation 114 2004 857 866 (Pubitemid 39578745)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.6
, pp. 857-866
-
-
Sugimoto, K.1
Ohata, M.2
Miyoshi, J.3
Ishizaki, H.4
Tsuboi, N.5
Masuda, A.6
Yoshikai, Y.7
Takamoto, M.8
Sugane, K.9
Matsuo, S.10
Shimada, Y.11
Matsuguchi, T.12
-
53
-
-
0032813905
-
Genistein inhibits constitutive and inducible NFB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells
-
O. Tabary, S. Escotte, J.P. Couetil, D. Hubert, D. Dusser, and E. Puchelle et al. Genistein inhibits constitutive and inducible NF kappa B activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells American Journal of Pathology 155 1999 473 481 (Pubitemid 29370397)
-
(1999)
American Journal of Pathology
, vol.155
, Issue.2
, pp. 473-481
-
-
Tabary, O.1
Escotte, S.2
Couetil, J.P.3
Hubert, D.4
Dusser, D.5
Puchelle, E.6
Jacquot, J.7
-
54
-
-
84868255280
-
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia
-
G. Veit, F. Bossard, J. Goepp, A.S. Verkman, L.J.V. Galietta, and J.W. Hanrahan et al. Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia Molecular Biology of the Cell 23 2012 4188 4202
-
(2012)
Molecular Biology of the Cell
, vol.23
, pp. 4188-4202
-
-
Veit, G.1
Bossard, F.2
Goepp, J.3
Verkman, A.S.4
Galietta, L.J.V.5
Hanrahan, J.W.6
-
55
-
-
58149288281
-
Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii
-
W.T. Watford, B.D. Hissong, L.R. Durant, H. Yamane, L.M. Muul, and Y. Kanno et al. Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii Journal of Experimental Medicine 205 2008 2803 2812
-
(2008)
Journal of Experimental Medicine
, vol.205
, pp. 2803-2812
-
-
Watford, W.T.1
Hissong, B.D.2
Durant, L.R.3
Yamane, H.4
Muul, L.M.5
Kanno, Y.6
-
56
-
-
66349091863
-
Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood
-
J. Wu, N. Green, R. Hotchandani, Y. Hu, J. Condon, and A. Huang et al. Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood Bioorganic & Medicinal Chemistry Letters 19 2009 3485 3488
-
(2009)
Bioorganic & Medicinal Chemistry Letters
, vol.19
, pp. 3485-3488
-
-
Wu, J.1
Green, N.2
Hotchandani, R.3
Hu, Y.4
Condon, J.5
Huang, A.6
-
57
-
-
0035260351
-
Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate
-
Z.L. Zhang, P. Oliver, J.R. Lancaster, P.O. Schwarzenberger, M.S. Joshi, and J. Cork et al. Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate FASEB Journal 15 2001 303 305
-
(2001)
FASEB Journal
, vol.15
, pp. 303-305
-
-
Zhang, Z.L.1
Oliver, P.2
Lancaster, J.R.3
Schwarzenberger, P.O.4
Joshi, M.S.5
Cork, J.6
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