The Protein Kinase TPL2 Is Essential for ERK1/ERK2 Activation and Cytokine Gene Expression in Airway Epithelial Cells Exposed to Pathogen-Associated Molecular Patterns (PAMPs)

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Martel, Guy ^a   Bérubé, Julie ^a   Rousseau, Simon ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PRODUCT; EPIDERMAL GROWTH FACTOR RECEPTOR; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIGAND; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PATHOGEN ASSOCIATED MOLECULAR PATTERN; PROTEIN KINASE; RAF PROTEIN; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 5; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR PROGRESSION LOCUS 2 PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; RESPIRATORY EPITHELIUM;

CELL LINE, TRANSFORMED; CYTOKINES; ENZYME ACTIVATION; EPITHELIAL CELLS; HUMANS; I-KAPPA B KINASE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; PSEUDOMONAS AERUGINOSA; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; TOLL-LIKE RECEPTORS;

EID: 84875108470     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059116     Document Type: Article

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