Equol induces apoptosis in human hepatocellular carcinoma SMMC-7721 cells through the intrinsic pathway and the endoplasmic reticulum stress pathway

Anti-Cancer Drugs

Volumn 25, Issue 6, 2014, Pages 633-640

  Liang, Xiao Lin ^a,b   Li, Meng ^a   Li, Jing ^a,b   Wang, Xiu Ling ^a  

^a AGRICULTURAL UNIVERSITY OF HEBEI   (China)

^b North China Pharmaceutical Corporation   (China)

Author keywords

Apoptosis; Chemoprevention; Endoplasmic reticulum stress pathway; Equol; Human hepatocellular carcinoma SMMC 7721 cells; Intrinsic pathway

Indexed keywords

CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; EQUOL; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRUCTURE; CHIRALITY; CONCENTRATION RESPONSE; CYTOTOXICITY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PERFORMANCE; PRIORITY JOURNAL; S PHASE CELL CYCLE CHECKPOINT; SIGNAL TRANSDUCTION; UPREGULATION; CELL CYCLE; CHEMISTRY; DRUG EFFECTS; LIVER TUMOR; METABOLISM; MITOCHONDRION; PATHOLOGY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; EQUOL; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; SIGNAL TRANSDUCTION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84901637030     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0000000000000085     Document Type: Article

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