Nanoparticle-encapsulated vis- and NIR-emissive fluorophores with different fluorescence decay kinetics for lifetime multiplexing Multiplex Platforms in Diagnostics and Bioanalytics

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 14, 2014, Pages 3315-3322

  Hoffmann, Katrin ^a   Behnke, Thomas ^a   Grabolle, Markus ^a   Resch Genger, Ute ^a  

^a BAM FEDERAL INSTITUTE FOR MATERIALS RESEARCH AND TESTING   (Germany)

Author keywords

Fluorescence lifetime imaging FLIM; Fluorescent label; Lifetime multiplexing; Multiplexing; Nanoparticles; Optical encoding

Indexed keywords

EMISSION SPECTROSCOPY; ENCODING (SYMBOLS); FLUORESCENCE; INFRARED DEVICES; KINETICS; LIQUID CHROMATOGRAPHY; MOLECULAR IMAGING; MULTIPLEXING; NANOPARTICLES; OPTICAL DATA PROCESSING; SUSPENSIONS (FLUIDS);

ABSORPTION AND EMISSION SPECTRA; CHROMATOGRAPHIC SEPARATIONS; FLUORESCENCE LIFETIME IMAGING; FLUORESCENCE LIFETIMES; FLUORESCENT LABELS; OPTICAL ENCODING; POLYMERIC NANOPARTICLES; POLYSTYRENE NANOPARTICLES;

FLUOROPHORES;

FLUORESCENT DYE; NANOPARTICLE; POLYMER;

3T3 CELL LINE; ANIMAL; CHEMISTRY; COMPUTER INTERFACE; CYTOLOGY; FLOW CYTOMETRY; MOUSE; NANOTECHNOLOGY; NEAR INFRARED SPECTROSCOPY; SPECTROFLUOROMETRY; STAINING;

3T3 CELLS; ANIMALS; CYTOLOGICAL TECHNIQUES; FLOW CYTOMETRY; FLUORESCENT DYES; MICE; NANOPARTICLES; NANOTECHNOLOGY; POLYMERS; SPECTROMETRY, FLUORESCENCE; SPECTROSCOPY, NEAR-INFRARED; STAINING AND LABELING; USER-COMPUTER INTERFACE;

EID: 84901608506     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-7597-3     Document Type: Article

References (38)

1. Nolan JP, Mandy F (2006) Multiplexed and microparticle-based analyses: quantitative tools for the large-scale analysis of biological systems. Cytometry Part A 69A(5):318-325 (Pubitemid 44651344)
2. Ugozzoli LA (2004) Multiplex assays with fluorescent microbead readout: a powerful tool for mutation detection. Clin Chem 50(11):1963-1965 (Pubitemid 39425827)
3. Shepard JRE (2006) Polychromatic microarrays: simultaneous multicolor array hybridization of eight samples. Anal Chem 78(8):3589-3597
4. Evans M, Sewter C, Hill E (2003) An encoded particle array tool for multiplex bioassays. Assay Drug Dev Technol 1(1):199-207
5. De Rosa SC, Brenchley JM, Roederer M (2003) Beyond six colors: a new era in flow cytometry. Nat Med 9(1):112-117 (Pubitemid 36098271)
6. Lieberwirth U, Arden-Jacob J, Drexhage KH, Herten DP, Muller R, Neumann M, Schulz A, Siebert S, Sagner G, Klingel S, Sauer M, Wolfrum J (1998) Multiplex dye DNA sequencing in capillary gel electrophoresis by diode laser-based time-resolved fluorescence detection. Anal Chem 70(22):4771-4779 (Pubitemid 28532952)
7. Grabolle M, Kapusta P, Nann T, Shu X, Ziegler J, Resch-Genger U (2009) Fluorescence lifetime multiplexing with nanocrystals and organic labels. Anal Chem 81(18):7807-7813
8. Song EQ, Hu J, Wen CY, Tian ZQ, Yu X, Zhang ZL, Shi YB, Pang DW (2011) Fluorescent-magnetic-biotargeting multifunctional nanobioprobes for detecting and isolating multiple types of tumor cells. ACS Nano 5(2):761-770
9. Lakowicz JR (2006) Principles of fluorescence spectroscopy. Principles of fluorescence spectroscopy, 3rd edn. Springer, New York
10. Resch-Genger U, Grabolle M, Cavaliere-Jaricot S, Nitschke R, Nann T (2008) Quantum dots versus organic dyes as fluorescent labels. Nat Methods 5(9):763-775
11. Hotzer B, Medintz IL, Hildebrandt N (2012) Fluorescence in nanobiotechnology: sophisticated fluorophores for novel applications. Small 8(15):2297-2326
12. Hemmila I, Laitala V (2005) Progress in lanthanides as luminescent probes. J Fluoresc 15(4):529-542 (Pubitemid 41361160)
13. Battersby BJ, Trau M (2007) Optically encoded particles and their applications in multiplexed biomedical assays. Aust J Chem 60(5):343-353 (Pubitemid 46835885)
14. Raymond SB, Boas DA, Bacskai BJ, Kumar ATN (2010) Lifetime-based tomographic multiplexing. J Biomed Opt 15(4):046011
15. Ehlert O, Thomann R, Darbandi M, Nann T (2008) A four-color colloidal multiplexing nanoparticle system. ACS Nano 2(1):120-124 (Pubitemid 351585771)
16. Hoffmann K, Behnke T, Drescher D, Kneipp J, ReschGenger U (2011) Lifetime-based discrimination between spectrally matching vis and NIR emitting particle labels and probes. In: Proceedings of SPIE, 2011, single molecule spectroscopy and imaging IV
17. Hoffmann K, Behnke T, Drescher D, Kneipp J, Resch-Genger U (2013) Near-infrared-emitting nanoparticles for lifetime-based multiplexed analysis and imaging of living cells. ACS Nano 7(8):6674-6684
18. Behnke T, Würth C, Hoffmann K, Hubner M, Panne U, Resch-Genger U (2011) Encapsulation of hydrophobic dyes in polystyrene micro- and nanoparticles via swelling procedures. J Fluoresc 21(3):937-944
19. Behnke T, Würth C, Laux EM, Hoffmann K, Resch-Genger U (2012) Simple strategies towards bright polymer particles via one-step staining procedures. Dyes Pigments 94(2):247-257
20. Napp J, Behnke T, Fischer L, Wurth C, Wottawa M, Katschinski DM, Alves F, Resch-Genger U, Schaferling M (2011) Targeted luminescent near-infrared polymer-nanoprobes for in vivo imaging of tumor hypoxia. Anal Chem 83(23):9039-9046
21. Seydack M (2005) Nanoparticle labels in immunosensing using optical detection methods. Biosens Bioelectron 20(12):2454-2469 (Pubitemid 40613010)
22. Burns A, Ow H, Wiesner U (2006) Fluorescent core-shell silica nanoparticles: towards "lab on a particle" architectures for nanobiotechnology. Chem Soc Rev 35(11):1028-1042 (Pubitemid 44611717)
23. Yan JL, Estevez MC, Smith JE, Wang KM, He XX, Wang L, Tan WH (2007) Dye-doped nanoparticles for bioanalysis. Nano Today 2(3):44-50 (Pubitemid 46695432)
24. Wolfbeis OS (2005) Materials for fluorescence-based optical chemical sensors. J Mater Chem 15(27-28):2657-2669 (Pubitemid 41048660)
25. Sharma P, Brown S, Walter G, Santra S, Moudgil B (2006) Nanoparticles for bioimaging. Adv Colloid Interface Sci 123(126):471-485 (Pubitemid 44665822)
26. Miletto I, Gilardino A, Zamburlin P, Dalmazzo S, Lovisolo D, Caputo G, Viscardi G, Martra G (2010) Highly bright and photostable cyanine dye-doped silica nanoparticles for optical imaging: photophysical characterization and cell tests. Dyes Pigments 84(1):121-127
27. Behnke T, Mathejczyk JE, Brehm R, Würth C, Gomes FR, Dullin C, Napp J, Alves F, Resch-Genger U (2013) Target-specific nanoparticles containing a broad band emissive NIR dye for the sensitive detection and characterization of tumor development. Biomaterials 34(1):160-170
28. BASF Dispersions & Pigments North America (2013) http://www. dispersions-pigments.basf.us/p02/USWeb-Internet/pigments/en-GB/content/ microsites/pigmentsdispersions/products/Lumogen. Accessed 6 Jan 2014
29. Behnke T, Hoffmann A, Hoffmann K, Resch-Genger U (2010) DE Patent DE102008040513 Verwendung einer langwellig emittierenden Cyaninverbindung als NIR-Fluoreszenzstandard und Kit zur Kalibrierung von Photolumineszenzmesssystemen
30. Patsenker LD, Tatarets AL, Povrozin YA, Terpetschnig EA (2011) Long-wavelength fluorescence lifetime labels. Bioanal Rev 3:115-137
31. Laux EM, Behnke T, Hoffmann K, Resch-Genger U (2012) Keeping particles brilliant - simple methods for the determination of the dye content of fluorophore-loaded polymeric particles. Anal Methods 4(6):1759-1768
32. Resch-Genger U, Pfeifer D, Monte C, Pilz W, Hoffmann A, Spieles M, Rurack K, Hollandt J, Taubert D, Schonenberger B, Nording P (2005) Traceability in fluorometry: part II. Spectral fluorescence standards. J Fluoresc 15(3):315-336 (Pubitemid 40963140)
33. Krämer B, Koberling F, Tannert A, Korte T, Hermann A (2005) Fluorescence lifetime imaging (FLIM) based analysis of lipid organization in hepatocytes using the MicroTime 200. PicoQuant, Berlin
34. PicoQuant (2008) Picoquant application note SymphoTime software; http://www.picoquant.de/technotes/appnote-spt-demo-workspace.pdf. Accessed 8 Oct 2013
35. Berezin MY, Akers WJ, Guo K, Fischer GM, Daltrozzo E, Zumbusch A, Achilefu S (2009) Long fluorescence lifetime molecular probes based on near infrared pyrrolopyrrole cyanine fluorophores for in vivo imaging. Biophys J 97(9):L22-L24
36. Nothdurft R, Sarder P, Bloch S, Culver J, Achilefu S (2012) Fluorescence lifetime imaging microscopy using near-infrared contrast agents. J Microsc 247(2):202-207
37. Berezin MY, Achilefu S (2010) Fluorescence lifetime measurements and biological imaging. Chem Rev 110(5):2641-2684
38. Abbasi AZ, Amin F, Niebling T, Friede S, Ochs M, Carregal-Romero S, Montenegro JM, Gil PR, Heimbrodt W, Parak WJ (2011) How colloidal nanoparticles could facilitate multiplexed measurements of different analytes with analyte-sensitive organic fluorophores. ACS Nano 5(1):21-25