Tumor-targeting properties of novel immunocytokines based on murine IL1β and IL6

Protein Engineering, Design and Selection

Volumn 27, Issue 6, 2014, Pages 207-213

  Hess, Christian ^a   Neri, Dario ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

cancer; F8 antibody; immunocytokine; interleukin 1 ; interleukin 6; targeting

Indexed keywords

ANTHROPOMETRY; BINDING ENERGY; ELECTROPHORESIS; MONOCLONAL ANTIBODIES; PROTEINS; SIZE EXCLUSION CHROMATOGRAPHY; SODIUM DODECYL SULFATE;

CANCER; IMMUNOCYTOKINE; INTERLEUKIN-1; INTERLEUKIN-6; TARGETING;

TUMORS;

DODECYL SULFATE SODIUM; FIBRONECTIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY F8; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 6; UNCLASSIFIED DRUG; F8 MONOCLONAL ANTIBODY; HYBRID PROTEIN; IL1B PROTEIN, MOUSE; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG TARGETING; FEMALE; HUMAN; IMMUNOPHARMACOLOGY; IN VIVO STUDY; MOLECULAR CLONING; MOUSE; NONHUMAN; PLASMA CLEARANCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; WEIGHT REDUCTION; 129 MOUSE; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; CHO CELL LINE; CRICETULUS; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG SCREENING; HAMSTER; IMMUNOLOGY; PATHOLOGY; TERATOCARCINOMA; TISSUE DISTRIBUTION; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; FIBRONECTINS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MICE, 129 STRAIN; NEOPLASM TRANSPLANTATION; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; TERATOCARCINOMA; TISSUE DISTRIBUTION; TUMOR BURDEN;

EID: 84901456581     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzu013     Document Type: Article

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