Levels of IL-1 beta control stimulatory/inhibitory growth of cancer cells

Frontiers in Bioscience

Volumn 11, Issue 1 P.889-1198, 2006, Pages 889-898

  Roy, Deodutta ^a   Sarkar, Shubhashish ^a   Felty, Quentin ^a  

^a FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Cancer; Cell Growth; Cytokine; Estrogen; Genotoxic Damages; Interleukin 1 beta; Neoplasia; Review; TNG; Tumor

Indexed keywords

EID: 32944455363     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1845     Document Type: Review

References (82)

1. Roy, D. & J. G. Liehr: Inhibition of estrogen-induced kidney carcinogenesis in Syrian hamsters by modulators of estrogen metabolism. Carcinogenesis 11, 567-570 (1990)
2. International Agency for Research on Cancer Working Group Monographs on the evaluation of hormonal contraception and postmenopausal hormonal therapy. 399-530 (1999)
3. National Toxicology Program Federal report on carcinogens. 77283-77285 (2002)
4. NCI Uses of hormones after menopause. NCI - (2003)
5. Roy, D. & Q. Cai: Estrogen, immunoactivation, gene damage, and development of breast, endometrial, ovarian, prostate, and testicular cancers. Recent Res Devel Steroid Biochem Mol Biol 3, 1-32 (2002)
6. Roy, D. & K. P. Singh: Estrogen-induced genetic alterations and their role in carcinogenicity. Curr Genomics 5, 245-257 (2004)
7. Liehr, J. G. & D. Roy: Free radical generation by redox cycling of estrogens. Free Radic Biol Med 8, 415-423 (1990)
8. Markides, C. S., D. Roy, & J. G. Liehr: Concentration dependence of prooxidant and antioxidant properties of catecholestrogens. Arch Biochem Biophys 360, 105-112 (1998)
9. Roy, D., B. Kalyanaraman, & J. G. Liehr: Xanthine oxidase-catalyzed reduction of estrogen quinones to semiquinones and hydroquinones. Biochem Pharmacol 42, 1627-1631 (1991)
10. Roy, D. & J. G. Liehr: Estrogen, DNA damage and mutations. Mutat Res 424, 107-115 (1999)
11. Cavalieri, E., K. Frenkel, J. G. Liehr, E. Rogan, & D. Roy: Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J Natl Cancer Inst Monogr 75-93 (2000)
12. Zhang, F., S. M. Swanson, R. B. van Breemen, X. Liu, Y. Yang, C. Gu, & J. L. Bolton: Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases. Chem Res Toxicol 14, 1654-1659 (2001)
13. Embrechts, J., F. Lemiere, W. Van Dongen, E. L. Esmans, P. Buytaert, E. Van Marck, M. Kockx, & A. Makar: Detection of estrogen DNA-adducts in human breast tumor tissue and healthy tissue by combined nano LC-nano ES tandem mass spectrometry. J Am Soc Mass Spectrom 14, 482-491 (2003)
14. Devanesan, P., R. J. Santen, W. P. Bocchinfuso, K. S. Korach, E. G. Rogan, & E. Cavalieri: Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor-alpha knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors. Carcinogenesis 22, 1573-1576 (2001)
15. Terashima, I., N. Suzuki, & S. Shibutani: Mutagenic properties of estrogen quinone-derived DNA adducts in simian kidney cells. Biochemistry 40, 166-172 (2001)
16. Chakravarti, D., P. C. Mailander, K. M. Li, S. Higginbotham, H. L. Zhang, M. L. Gross, J. L. Meza, E. L. Cavalieri, & E. G. Rogan: Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene. Oncogene 20, 7945-7953 (2001)
17. Roy D, Parkash J, & Narayan S: Genetics and Bioenergetics of Mitochondria Influencing the Etiology and Pharmacology of Steroidal Hormones. Current Pharmacogenomics 2, 379-390 (2005)
18. Felty, Q. & D. Roy: Mitochondrial signals to nucleus regulate estrogen-induced cell growth. Med Hypotheses 64, 133-141 (2005)
19. Felty, Q. & D. Roy: Estrogen, mitochondria, and growth of cancer and non-cancer cells. J Carcinog 4, 1- (2005)
20. Felty, Q., W. C. Xiong, D. Sun, S. Sarkar, K. P. Singh, J. Parkash, & D. Roy: Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers. Biochemistry 44, 6900-6909 (2005)
21. Malins, D. C. & R. Haimanot: Major alterations in the nucleotide structure of DNA in cancer of the female breast. Cancer Res 51, 5430-5432 (1991)
22. Malins, D. C., N. L. Polissar, K. Nishikida, E. H. Holmes, H. S. Gardner, & S. J. Gunselman: The etiology and prediction of breast cancer. Fourier transform-infrared spectroscopy reveals progressive alterations in breast DNA leading to a cancer-like phenotype in a high proportion of normal women. Cancer 75, 503-517 (1995)
23. Musarrat, J., J. Arezina-Wilson, & A. A. Wani: Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis. Eur J Cancer 32A, 1209-1214 (1996)
24. Yamamoto, T., K. Hosokawa, T. Tamura, H. Kanno, M. Urabe, & H. Honjo: Urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels in women with or without gynecologic cancer. J Obstet Gynaecol Res 22, 359-363 (1996)
25. Singh K, Lopez-Guerrero JA, Llombart-Bosch A, & Roy D. Estrogen-induced mutations and its role in the development of tumorigenesis. Hormonal Carcinogenesis IV, Li, Jonathan J.; Li, Sara A.; Llombart-Bosch, Antonio (Eds.) Springer-Verlag, (2005)
26. Kong, L. Y., P. Szaniszlo, T. Albrecht, & J. G. Liehr: Frequency and molecular analysis of hprt mutations induced by estradiol in Chinese hamster V79 cells. Int J Oncol 17, 1141-1149 (2000)
27. Dinarello, C. A. & N. Savage: Interleukin-1 and its receptor. Crit Rev Immunol 9, 1-20 (1989)
28. Dinarello, C. A. Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147 (1996)
29. Hu, S. K., Y. L. Mitcho, & N. C. Rath: Effect of estradiol on interleukin 1 synthesis by macrophages. Int J Immunopharmacol 10, 247-252 (1988)
30. Harris, M. T., R. S. Feldberg, K. M. Lau, N. H. Lazarus, & D. E. Cochrane: Expression of proinflammatory genes during estrogen-induced inflammation of the rat prostate. Prostate 44, 19-25 (2000)
31. Yoshida, Y., Y. Nakamura, N. Sugino, K. Shimamura, M. Ono, & H. Kato: Changes in interleukin-1 production of peritoneal macrophages during estrous cycle in golden hamsters. Endocr J 43, 151-156 (1996)
32. Polan, M. L., A. Daniele, & A. Kuo: Gonadal steroids modulate human monocyte interleukin-1 (IL-1) activity. Fertil Steril 49, 964-968 (1988)
33. Nash, M. A., G. Ferrandina, M. Gordinier, A. Loercher, & R. S. Freedman: The role of cytokines in both the normal and malignant ovary. Endocr Relat Cancer 6, 93-107 (1999)
34. Li, B. Y., D. Mohanraj, M. C. Olson, M. Moradi, L. Twiggs, L. F. Carson, & S. Ramakrishnan: Human ovarian epithelial cancer cells cultures in vitro express both interleukin 1 alpha and beta genes. Cancer Res 52, 2248-2252 (1992)
35. Scambia, G., U. Testa, P. B. Panici, R. Martucci, E. Foti, M. Petrini, M. Amoroso, V. Masciullo, C. Peschle, & S. Mancuso: Interleukin-6 serum levels in patients with gynecological tumors. Int J Cancer 57, 318-323 (1994)
36. Miller, L. J., S. H. Kurtzman, K. Anderson, Y. Wang, M. Stankus, M. Renna, R. Lindquist, G. Barrows, & D. L. Kreutzer Interleukin-1 family expression in human breast cancer: interleukin-1 receptor antagonist. Cancer Invest 18, 293-302 (2000)
37. Jin, L., R. Q. Yuan, A. Fuchs, Y. Yao, A. Joseph, R. Schwall, S. J. Schnitt, A. Guida, H. M. Hastings, J. Andres, G. Turkel, P. J. Polverini, I. D. Goldberg, & E. M. Rosen: Expression of interleukin-1beta in human breast carcinoma. Cancer 80, 421-434 (1997)
38. Bhat-Nakshatri, P., T. R. Newton, R. Goulet, Jr., & H. Nakshatri: NF-kappaB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1alpha. Proc Natl Acad Sci U S A 95, 6971-6976 (1998)
39. Pantschenko, A. G., I. Pushkar, K. H. Anderson, Y. Wang, L. J. Miller, S. H. Kurtzman, G. Barrows, & D. L. Kreutzer: The interleukin-1 family of cytokines and receptors in human breast cancer: implications for tumor progression. Int J Oncol 23, 269-284 (2003)
40. Robinette, C. L. Sex-hormone-induced inflammation and fibromuscular proliferation in the rat lateral prostate. Prostate 12, 271-286 (1988)
41. Burrows, F. J., D. O. Haskard, I. R. Hart, J. F. Marshall, S. Selkirk, S. Poole, & P. E. Thorpe: Influence of tumor-derived interleukin 1 on melanoma-endothelial cell interactions in vitro. Cancer Res 51, 4768-4775 (1991)
42. Vidal-Vanaclocha F, A. A. A. A. A. M. D. C. Juxtacrine activation of liver sinusoidal endothelium by B16 melanoma cell surface-associated IL-1 stimulates on site release of prometastatic factors. 119-123 (1995)
43. Wu, S., W. A. Meeker, J. R. Wiener, A. Berchuck, R. C. Bast, Jr., & C. M. Boyer: Transfection of ovarian cancer cells with tumor necrosis factor-alpha (TNF-alpha) antisense mRNA abolishes the proliferative response to interleukin-1 (IL-1) but not TNF-alpha. Gynecol Oncol 53, 59-63 (1994)
44. Wu, S., C. M. Boyer, R. S. Whitaker, A. Berchuck, J. R. Wiener, J. B. Weinberg, & R. C. Bast, Jr.: Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. Cancer Res 53, 1939-1944 (1993)
45. Morioka, M., K. Shimodaira, Y. Kuwano, H. Fujikawa, H. Saito, & T. Yanaihara: Effect of interleukin-1beta on aromatase activity and cell proliferation in human osteoblast-like cells (HOS). Biochem Biophys Res Commun 268, 60-64 (2000)
46. Honma, S., K. Shimodaira, Y. Shimizu, N. Tsuchiya, H. Saito, T. Yanaihara, & T. Okai: The influence of inflammatory cytokines on estrogen production and cell proliferation in human breast cancer cells. Endocr J 49, 371-377 (2002)
47. Vesey, D. A., C. Cheung, L. Cuttle, Z. Endre, G. Gobe, & D. W. Johnson: Interleukin-1beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta- dependent mechanism. J Lab Clin Med 140, 342-350 (2002)
48. Stoker, T. E., C. L. Robinette, & R. L. Cooper: Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes. Reprod Toxicol 13, 463-472 (1999)
49. Kawamura, H. & I. Ichihara: Possible microapocrine-type secretion developing in prostatic secretory epithelial cells of older rats in the early stage of castration. Anal Anz 163, 289-300 (1987)
50. Hoosein, N. M. Neuroendocrine and immune mediators in prostate cancer progression. Front Biosci 3, D1274-D1279 (1998)
51. Tanaka, T., H. Kanai, K. Sekiguchi, Y. Aihara, T. Yokoyama, M. Arai, T. Kanda, R. Nagai, & M. Kurabayashi: Induction of VEGF gene transcription by IL-1 beta is mediated through stress-activated MAP kinases and Sp1 sites in cardiac myocytes. J Mol Cell Cardiol 32, 1955-1967 (2000)
52. Jung, Y. D., W. Liu, N. Reinmuth, S. A. Ahmad, F. Fan, G. E. Gallick, & L. M. Ellis: Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway. Angiogenesis 4, 155-162 (2001)
53. Guesdon, F., N. Freshney, R. J. Waller, L. Rawlinson, & J. Saklatvala: Interleukin 1 and tumor necrosis factor stimulate two novel protein kinases that phosphorylate the heat shock protein hsp27 and beta-casein. J Biol Chem 268, 4236-4243 (1993)
54. Coxon, A., B. Bolon, J. Estrada, S. Kaufman, S. Scully, A. Rattan, D. Duryea, Y. L. Hu, K. Rex, E. Pacheco, G. Van, D. Zack, & U. Feige: Inhibition of interleukin-1 but not tumor necrosis factor suppresses neovascularization in rat models of corneal angiogenesis and adjuvant arthritis. Arthritis Rheum 46, 2604-2612 (2002)
55. Dana, M. R., S. N. Zhu, & J. Yamada: Topical modulation of interleukin-1 activity in corneal neovascularization. Cornea 17, 403-409 (1998)
56. Saijo, Y., M. Tanaka, M. Miki, K. Usui, T. Suzuki, M. Maemondo, X. Hong, R. Tazawa, T. Kikuchi, K. Matsushima, & T. Nukiwa: Proinflammatory cytokine IL-1 beta promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors: in vivo analysis of tumor-stromal interaction. J Immunol 169, 469-475 (2002)
57. Song, X., E. Voronov, T. Dvorkin, E. Fima, E. Cagnano, D. Benharroch, Y. Shendler, O. Bjorkdahl, S. Segal, C. A. Dinarello, & R. N. Apte: Differential effects of IL-1 alpha and IL-1 beta on tumorigenicity patterns and invasiveness. J Immunol 171, 6448-6456 (2003)
58. Hedges, J. C., M. A. Dechert, I. A. Yamboliev, J. L. Martin, E. Hickey, L. A. Weber, & W. T. Gerthoffer: A role for p38(MAPK)/HSP27 pathway in smooth muscle cell migration. J Biol Chem 274, 24211-24219 (1999)
59. Giavazzi, R., A. Garofalo, M. R. Bani, M. Abbate, P. Ghezzi, D. Boraschi, A. Mantovani, & E. Dejana: Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice. Cancer Res 50, 4771-4775 (1990)
60. Apte, R. N., T. Dvorkin, X. Song, E. Fima, Y. Krelin, A. Yulevitch, R. Gurfinkel, A. Werman, R. M. White, S. Argov, Y. Shendler, O. Bjorkdahl, M. Dohlsten, M. Zoller, S. Segal, & E. Voronov: Opposing effects of IL-1 alpha and IL-1 beta on malignancy patterns. Tumor cell-associated IL-1 alpha potentiates anti-tumor immune responses and tumor regression, whereas IL-1 beta potentiates invasiveness. Adv Exp Med Biol 479, 277-288 (2000)
61. Vidal-Vanaclocha, F., G. Fantuzzi, L. Mendoza, A. M. Fuentes, M. J. Anasagasti, J. Martin, T. Carrascal, P. Walsh, L. L. Reznikov, S. H. Kim, D. Novick, M. Rubinstein, & C. A. Dinarello: IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci U S A 97, 734-739 (2000)
62. Vidal-Vanaclocha, F., C. Amezaga, A. Asumendi, G. Kaplanski, & C. A. Dinarello: Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases. Cancer Res 54, 2667-2672 (1994)
63. Yano, S., H. Nokihara, A. Yamamoto, H. Goto, H. Ogawa, T. Kanematsu, T. Miki, H. Uehara, Y. Saijo, T. Nukiwa, & S. Sone: Multifunctional interleukin-1 beta promotes metastasis of human lung cancer cells in SCID mice via enhanced expression of adhesion-, invasion- and angiogenesis-related molecules. Cancer Sci 94, 244-252 (2003)
64. Burdon, R. H. Oxyradicals as signal transducers. 1, 289-322 (1997)
65. Wang, S., S. S. Leonard, V. Castranova, V. Vallyathan, & X. Shi: The role of superoxide radical in TNF-alpha induced NF-kappaB activation. Ann Clin Lab Sci 29, 192-199 (1999)
66. Jackson, J. H., E. Gajewski, I. U. Schraufstatter, P. A. Hyslop, A. F. Fuciarelli, C. G. Cochrane, & M. Dizdaroglu: Damage to the bases in DNA induced by stimulated human neutrophils. J Clin Invest 84, 1644-1649 (1989)
67. Weitzman, S. A. & T. P. Stossel: Mutation caused by human phagocytes. Science 212, 546-547 (1981)
68. Delaney, C. A., D. Pavlovic, A. Hoorens, D. G. Pipeleers, & D. L. Eizirik: Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology 138, 2610-2614 (1997)
69. Bekesi, G., Z. Magyar, R. Kakucs, D. Sprintz, I. Kocsis, B. Szekacs, & J. Feher: [Changes in the myeloperoxidase activity of human neutrophilic granulocytes and the amount of enzyme deriving from them under the effect of estrogen]. Orv Hetil 140, 1625-1630 (1999)
70. Bekesi, G., R. Kakucs, S. Varbiro, J. Feher, T. Pazmany, Z. Magyar, D. Sprintz, & B. Szekacs: Induced myeloperoxidase activity and related superoxide inhibition during hormone replacement therapy. BJOG 108, 474-481 (2001)
71. Singh KP & Roy D: Estrogen-induced cell Proliferation of human kidney epithelial cells. The Toxicologist 78, - (2004)
72. Oberley, T. D., R. G. Allen, J. L. Schultz, & L. J. Lauchner: Antioxidant enzymes and steroid-induced proliferation of kidney tubular cells. Free Radic Biol Med 10, 79-83 (1991)
73. Pantschenko, A. G., I. Pushkar, L. J. Miller, Y. P. Wang, K. Anderson, Z. Peled, S. H. Kurtzman, & D. L. Kreutzer: In vitro demonstration of breast cancer tumor cell sub-populations based on interleukin-1/tumor necrosis factor induction of interleukin-8 expression. Oncol Rep 10, 1011-1017 (2003)
74. Kuno, K. & K. Matsushima: The IL-1 receptor signaling pathway. J Leukoc Biol 56, 542-547 (1994)
75. Rossi, B. IL-1 transduction signals. Eur Cytokine Netw 4, 181-187 (1993)
76. O'Neill, L. A., T. A. Bird, & J. Saklatvala: How does interleukin 1 activate cells? Interleukin 1 signal transduction. Immunol Today 11, 392-394 (1990)
77. Rosoff, P. M., N. Savage, & C. A. Dinarello: Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism. Cell 54, 73-81 (1988)
78. Rosoff, P. M. Characterization of the interleukin-1-stimulated phospholipase C activity in human T lymphocytes. LymphokineRes 8, 407-413 (1989)
79. Andrieu, N., R. Salvayre, & T. Levade: Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor- and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts. Biochem J 303 ( Pt 2), 341-345 (1994)
80. Bird, T. A., P. R. Sleath, P. C. deRoos, S. K. Dower, & G. D. Virca: Interleukin-1 represents a new modality for the activation of extracellular signal-regulated kinases/microtubule-associated protein-2 kinases. J Biol Chem 266, 22661-22670 (1991)
81. Venkat, S., Q. Felty, & D. Roy: Estrogen-induced stimulation of macrophages leading to the generation of reactive oxygen species in the target organ of cancer. Toxicologist 67, 235 (2003)
82. Felty, Q., K. P. Singh, & D. Roy: Estrogen-induced G(1)/S transition of G(0)-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling. Oncogene 24, 4883-4893 (2005)