Beyond Framingham risk factors and coronary calcification: Does aortic valve calcification improve risk prediction? the Heinz Nixdorf Recall Study

Heart

Volumn 100, Issue 12, 2014, Pages 930-937

  Kälsch, Hagen ^a   Lehmann, Nils ^b   Mahabadi, Amir A ^a   Bauer, Marcus ^a   Kara, Kaffer ^a   Hüppe, Patricia ^a   Moebus, Susanne ^b   Möhlenkamp, Stefan ^c   Dragano, Nico ^d   Schmermund, Axel ^e   Stang, Andreas ^f   Jöckel, Karl Heinz ^b   Erbel, Raimund ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c Krankenhaus Bethanien   (Germany)

^d UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^e Cardioangiological Center Bethanien   (Germany)

^f MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AORTA VALVE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY CALCIFICATION; ECHOCARDIOGRAPHY; ELECTRON BEAM TOMOGRAPHY; FEMALE; FRAMINGHAM RISK SCORE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SCORING SYSTEM;

AGED; AORTIC VALVE; CALCINOSIS; CHI-SQUARE DISTRIBUTION; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; DISEASE-FREE SURVIVAL; FEMALE; GERMANY; HEART DEFECTS, CONGENITAL; HEART VALVE DISEASES; HUMANS; INCIDENCE; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; STROKE; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; VASCULAR CALCIFICATION;

EID: 84901450380     PISSN: 13556037     EISSN: 1468201X     Source Type: Journal    
DOI: 10.1136/heartjnl-2013-305205     Document Type: Article

References (27)

1. Otto CM, Lind BK, Kitzman DW, et al. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med 1999;341:142-7. (Pubitemid 29325741)
2. Mahabadi AA, Bamberg F, Toepker M, et al. Association of aortic valve calcification to the presence, extent, and composition of coronary artery plaque burden: from the Rule Out Myocardial Infarction using Computer Assisted Tomography (ROMICAT) trial. Am Heart J 2009;158:562-8.
3. Katz R, Wong ND, Kronmal R, et al. Features of the metabolic syndrome and diabetes mellitus as predictors of aortic valve calcification in the Multi-Ethnic Study of Atherosclerosis. Circulation 2006;113:2113-19.
4. Pohle K, Maffert R, Ropers D, et al. Progression of aortic valve calcification: association with coronary atherosclerosis and cardiovascular risk factors. Circulation 2001;104:1927-32. (Pubitemid 32983236)
5. Messika-Zeitoun D, Bielak LF, Peyser PA, et al. Aortic valve calcification: determinants and progression in the population. Arterioscler Thromb Vasc Biol 2007;27:642-8.
6. Koos R, Mahnken AH, Kuhl HP, et al. Quantification of aortic valve calcification using multislice spiral computed tomography: comparison with atomic absorption spectroscopy. Invest Radiol 2006;41:485-9. (Pubitemid 44284197)
7. Utsunomiya H, Yamamoto H, Kunita E, et al. Combined presence of aortic valve calcification and mitral annular calcification as a marker of the extent and vulnerable characteristics of coronary artery plaque assessed by 64-multidetector computed tomography. Atherosclerosis 2010;213:166-72.
8. Owens DS, Budoff MJ, Katz R, et al. Aortic valve calcium independently predicts coronary and cardiovascular events in a primary prevention population. JACC Cardiovasc Imaging 2012;5:619-25.
9. Erbel R, Möhlenkamp S, Moebus S, et al., for the Heinz Nixdorf Recall Study Investigative Group. Coronary risk stratification, discrimination, and reclassification improvement based on quantification of subclinical coronary atherosclerosis: the Heinz Nixdorf Recall Study. J Am Coll Cardiol 2010;56:1397-406.
10. Schmermund A, Möhlenkamp S, Stang A, et al. Assessment of clinically silent atherosclerotic disease and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: rationale and design of the Heinz Nixdorf RECALL Study. Risk Factors, Evaluation of Coronary Calcium and Lifestyle. Am Heart J 2002;144:212-18. (Pubitemid 34879641)
11. Stang A, Moebus S, Dragano N, et al. Baseline recruitment and analysis of nonresponse of Heinz Nixdorf Recall Study: identifiability of phone numbers as the major determinant of response. Euro J Epidemiol 2005;20:489-96. (Pubitemid 40933925)
12. Wilson PW, D'Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837-47. (Pubitemid 28213628)
13. Schmermund A, Mohlenkamp S, Berenbein S, et al. Population-based assessment of subclinical coronary atherosclerosis using electron-beam computed tomography. Atherosclerosis 2006;185:177-82. (Pubitemid 43117566)
14. Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 1990;15:827-32. (Pubitemid 20101575)
15. Messika-Zeitoun D, Aubry MC, Detaint D, et al. Evaluation and clinical implications of aortic valve calcification measured by electron-beam computed tomography. Circulation 2004;110:356-62. (Pubitemid 38955506)
16. Nasir K, Katz R, Al-Mallah M, et al. Relationship of aortic valve calcification with coronary artery calcium severity: the Multi-Ethnic Study of Atherosclerosis (MESA). J Cardiovasc Comput Tomogr 2010;4:41-6.
17. Rumberger JA, Simons DB, Fitzpatrick LA, et al. Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation 1995;92:2157-62.
18. Greenland P, LaBree L, Azen SP, et al. CAC score combined with Framingham score for risk prediction in asymptomatic individuals. JAMA 2004;291:210-15. (Pubitemid 38082815)
19. Detrano R, Guerci AD, Carr JJ, et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med 2008;358:1336-45. (Pubitemid 351468410)
20. Budoff MJ, Nasir K, Katz R, et al. Thoracic aortic calcification and coronary heart disease events: the multi-ethnic study of atherosclerosis (MESA). Atherosclerosis 2011;215:196-202.
21. Kälsch H, Lehmann N, Berg MH, et al. Coronary artery calcification outperforms thoracic aortic calcification for the prediction of myocardial infarction and all-cause mortality - the Heinz Nixdorf Recall Study. Eur J Prev Cardiol 2013. [Epub ahead of print]
22. Hermann DM, Gronewold J, Lehmann N, et al.; Heinz Nixdorf Recall Study Investigative Group. Coronary artery calcification is an independent stroke predictor in the general population. Stroke 2013;44:1008-13.
23. Lindroos M, Kupari M, Valvanne J, et al. Factors associated with calcific aortic valve degeneration in the elderly. Eur Heart J 1994;15:865-70. (Pubitemid 24223943)
24. Katz R, Budoff MJ, Takasu J, et al. Relationship of metabolic syndrome with incident aortic valve calcium and aortic valve calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes 2009;58:813-19.
25. Shah AM, Banerjee T, Mukherjee D. Coronary, peripheral and cerebrovascular disease: a complex relationship. Herz 2008;33:475-80.
26. Kälsch H, Lehmann N, Möhlenkamp S, et al.; On behalf of the Investigator Group of the Heinz Nixdorf Recall Study. Prevalence of thoracic aortic calcification and its relationship to cardiovascular risk factors and coronary calcification in an unselected population-based cohort - the Heinz Nixdorf Recall Study. Int J Cardiovasc Imaging 2013;29:207-16.
27. Walsh CR, Larson MG, Kupka MJ, et al. Association of aortic valve calcium detected by electron beam computed tomography with echocardiographic aortic valve disease and with calcium deposits in the coronary arteries and thoracic aorta. Am J Cardiol 2004;93:421-5. (Pubitemid 38221348)