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Volumn 349, Issue 2, 2014, Pages 128-135

Anti-angiogenesis participates in antitumor effects of metronomic capecitabine on colon cancer

Author keywords

Anti angiogenesis; Capecitabine; Colorectal cancer; CTX; Metronomic chemotherapy

Indexed keywords

CAPECITABINE; FLUOROURACIL; THROMBOSPONDIN 1; VASCULOTROPIN; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 84901413559     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.04.002     Document Type: Article
Times cited : (31)

References (40)
  • 2
    • 84867980802 scopus 로고    scopus 로고
    • Bevacizumab in combination with irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) in patients with metastatic colorectal cancer who were previously treated with oxaliplatin-containing regimens: a multicenter observational cohort study (TCTG 2nd-BV study)
    • Moriwaki T., Bando H., Takashima A., Yamazaki K., Esaki T., Yamashita K., Fukunaga M., Miyake Y., Katsumata K., Kato S., Satoh T., Ozeki M., Baba E., Yoshida S., Boku N., Hyodo I. Bevacizumab in combination with irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) in patients with metastatic colorectal cancer who were previously treated with oxaliplatin-containing regimens: a multicenter observational cohort study (TCTG 2nd-BV study). Med. Oncol. 2012, 29:2842-2848.
    • (2012) Med. Oncol. , vol.29 , pp. 2842-2848
    • Moriwaki, T.1    Bando, H.2    Takashima, A.3    Yamazaki, K.4    Esaki, T.5    Yamashita, K.6    Fukunaga, M.7    Miyake, Y.8    Katsumata, K.9    Kato, S.10    Satoh, T.11    Ozeki, M.12    Baba, E.13    Yoshida, S.14    Boku, N.15    Hyodo, I.16
  • 3
    • 84888131377 scopus 로고    scopus 로고
    • Fluorouracil, epirubicin, and cyclophosphamide (FEC-75) followed by paclitaxel plus trastuzumab versus paclitaxel plus trastuzumab followed by FEC-75 plus trastuzumab as neoadjuvant treatment for patients with HER2-positive breast cancer (Z1041): a randomised, controlled, phase 3 trial
    • Buzdar A.U., Suman V.J., Meric-Bernstam F., Leitch A.M., Ellis M.J., Boughey J.C., Unzeitig G., Royce M., McCall L.M., Ewer M.S., Hunt K.K. Fluorouracil, epirubicin, and cyclophosphamide (FEC-75) followed by paclitaxel plus trastuzumab versus paclitaxel plus trastuzumab followed by FEC-75 plus trastuzumab as neoadjuvant treatment for patients with HER2-positive breast cancer (Z1041): a randomised, controlled, phase 3 trial. Lancet Oncol. 2013, 14:1317-1325.
    • (2013) Lancet Oncol. , vol.14 , pp. 1317-1325
    • Buzdar, A.U.1    Suman, V.J.2    Meric-Bernstam, F.3    Leitch, A.M.4    Ellis, M.J.5    Boughey, J.C.6    Unzeitig, G.7    Royce, M.8    McCall, L.M.9    Ewer, M.S.10    Hunt, K.K.11
  • 5
    • 84892147161 scopus 로고    scopus 로고
    • Bevacizumab+ Capecitabine as maintenance therapy after initial Bevacizumab+ XELOX treatment in previously untreated patients with metastatic colorectal cancer: phase III 'stop and go'study results-a turkish oncology group trial
    • Yalcin S., Uslu R., Dane F., Yilmaz U., Zengin N., Buyukunal E., Buyukberber S., Camci C., Sencan O., Kilickap S. Bevacizumab+ Capecitabine as maintenance therapy after initial Bevacizumab+ XELOX treatment in previously untreated patients with metastatic colorectal cancer: phase III 'stop and go'study results-a turkish oncology group trial. Oncology 2013, 85:328-335.
    • (2013) Oncology , vol.85 , pp. 328-335
    • Yalcin, S.1    Uslu, R.2    Dane, F.3    Yilmaz, U.4    Zengin, N.5    Buyukunal, E.6    Buyukberber, S.7    Camci, C.8    Sencan, O.9    Kilickap, S.10
  • 6
    • 0041589524 scopus 로고    scopus 로고
    • Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
    • Bertolini F., Paul S., Mancuso P., Monestiroli S., Gobbi A., Shaked Y., Kerbel R.S. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. Cancer Res. 2003, 63:4342-4346.
    • (2003) Cancer Res. , vol.63 , pp. 4342-4346
    • Bertolini, F.1    Paul, S.2    Mancuso, P.3    Monestiroli, S.4    Gobbi, A.5    Shaked, Y.6    Kerbel, R.S.7
  • 10
    • 0034048358 scopus 로고    scopus 로고
    • Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
    • Hanahan D., Bergers G., Bergsland E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J. Clin. Invest. 2000, 105:1045-1047.
    • (2000) J. Clin. Invest. , vol.105 , pp. 1045-1047
    • Hanahan, D.1    Bergers, G.2    Bergsland, E.3
  • 11
    • 0036225444 scopus 로고    scopus 로고
    • Continuous low-dose anti-angiogenic/metronomic chemotherapy: from the research laboratory into the oncology clinic
    • Kerbel R.S., Klement G., Pritchard K.I., Kamen B. Continuous low-dose anti-angiogenic/metronomic chemotherapy: from the research laboratory into the oncology clinic. Ann. Oncol. 2002, 13:12-15.
    • (2002) Ann. Oncol. , vol.13 , pp. 12-15
    • Kerbel, R.S.1    Klement, G.2    Pritchard, K.I.3    Kamen, B.4
  • 13
    • 49649109964 scopus 로고    scopus 로고
    • Development of a preclinical model of spontaneous human melanoma central nervous system metastasis
    • Cruz-Munoz W., Man S., Xu P., Kerbel R.S. Development of a preclinical model of spontaneous human melanoma central nervous system metastasis. Cancer Res. 2008, 68:4500-4505.
    • (2008) Cancer Res. , vol.68 , pp. 4500-4505
    • Cruz-Munoz, W.1    Man, S.2    Xu, P.3    Kerbel, R.S.4
  • 15
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel R.S., Kamen B.A. The anti-angiogenic basis of metronomic chemotherapy. Nat. Rev. Cancer 2004, 4:423-436.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 17
    • 80455143255 scopus 로고    scopus 로고
    • Salvage therapy with oral metronomic cyclophosphamide and methotrexate for castration-refractory metastatic adenocarcinoma of the prostate resistant to docetaxel
    • Gebbia V., Serretta V., Borsellino N., Valerio M.R. Salvage therapy with oral metronomic cyclophosphamide and methotrexate for castration-refractory metastatic adenocarcinoma of the prostate resistant to docetaxel. Urology 2011, 78:1125-1130.
    • (2011) Urology , vol.78 , pp. 1125-1130
    • Gebbia, V.1    Serretta, V.2    Borsellino, N.3    Valerio, M.R.4
  • 19
    • 78650049959 scopus 로고    scopus 로고
    • VEGFR2 heterogeneity and response to anti-angiogenic low dose metronomic cyclophosphamide treatment
    • Patten S.G., Adamcic U., Lacombe K., Minhas K., Skowronski K., Coomber B.L. VEGFR2 heterogeneity and response to anti-angiogenic low dose metronomic cyclophosphamide treatment. BMC Cancer 2010, 10:683.
    • (2010) BMC Cancer , vol.10 , pp. 683
    • Patten, S.G.1    Adamcic, U.2    Lacombe, K.3    Minhas, K.4    Skowronski, K.5    Coomber, B.L.6
  • 20
    • 84859834841 scopus 로고    scopus 로고
    • First evidence that gamma-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-kappaB pathway
    • Manu K.A., Shanmugam M.K., Ramachandran L., Li F., Fong C.W., Kumar A.P., Tan P., Sethi G. First evidence that gamma-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-kappaB pathway. Clin. Cancer Res. 2012, 18:2220-2229.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 2220-2229
    • Manu, K.A.1    Shanmugam, M.K.2    Ramachandran, L.3    Li, F.4    Fong, C.W.5    Kumar, A.P.6    Tan, P.7    Sethi, G.8
  • 21
    • 34250637586 scopus 로고    scopus 로고
    • Biweekly oxaliplatin plus 1-day infusional fluorouracil/leucovorin followed by metronomic chemotherapy with tegafur/uracil in pretreated metastatic colorectal cancer
    • Lin P.C., Chen W.S., Chao T.C., Yang S.H., Tiu C.M., Liu J.H. Biweekly oxaliplatin plus 1-day infusional fluorouracil/leucovorin followed by metronomic chemotherapy with tegafur/uracil in pretreated metastatic colorectal cancer. Cancer Chemother. Pharmacol. 2007, 60:351-356.
    • (2007) Cancer Chemother. Pharmacol. , vol.60 , pp. 351-356
    • Lin, P.C.1    Chen, W.S.2    Chao, T.C.3    Yang, S.H.4    Tiu, C.M.5    Liu, J.H.6
  • 22
    • 84901192680 scopus 로고    scopus 로고
    • Multicenter phase II study of a new effective S-1 and irinotecan combination schedule in patients with unresectable metastatic or recurrent colorectal cancer
    • Ogata Y., Tanaka T., Akagi Y., Ishibashi N., Tsuji Y., Matono K., Isobe M., Sueyoshi S., Kaibara A., Shirouzu K. Multicenter phase II study of a new effective S-1 and irinotecan combination schedule in patients with unresectable metastatic or recurrent colorectal cancer. Clin. Med. Insights Oncol. 2013, 7:21-30.
    • (2013) Clin. Med. Insights Oncol. , vol.7 , pp. 21-30
    • Ogata, Y.1    Tanaka, T.2    Akagi, Y.3    Ishibashi, N.4    Tsuji, Y.5    Matono, K.6    Isobe, M.7    Sueyoshi, S.8    Kaibara, A.9    Shirouzu, K.10
  • 24
    • 84872084645 scopus 로고    scopus 로고
    • Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models
    • Hackl C., Man S., Francia G., Milsom C., Xu P., Kerbel R.S. Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models. Gut 2013, 62:259-271.
    • (2013) Gut , vol.62 , pp. 259-271
    • Hackl, C.1    Man, S.2    Francia, G.3    Milsom, C.4    Xu, P.5    Kerbel, R.S.6
  • 26
    • 84863056697 scopus 로고    scopus 로고
    • Capecitabine combined with (-)-epigallocatechin-3-gallate inhibits angiogenesis and tumor growth in nude mice with gastric cancer xenografts
    • Wu H., Xin Y., Xu C., Xiao Y. Capecitabine combined with (-)-epigallocatechin-3-gallate inhibits angiogenesis and tumor growth in nude mice with gastric cancer xenografts. Exp. Ther. Med. 2012, 3:650-654.
    • (2012) Exp. Ther. Med. , vol.3 , pp. 650-654
    • Wu, H.1    Xin, Y.2    Xu, C.3    Xiao, Y.4
  • 27
    • 79960411251 scopus 로고    scopus 로고
    • Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts
    • Naganuma Y., Choijamts B., Shirota K., Nakajima K., Ogata S., Miyamoto S., Kawarabayashi T., Emoto M. Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts. Cancer Sci. 2011, 102:1545-1552.
    • (2011) Cancer Sci. , vol.102 , pp. 1545-1552
    • Naganuma, Y.1    Choijamts, B.2    Shirota, K.3    Nakajima, K.4    Ogata, S.5    Miyamoto, S.6    Kawarabayashi, T.7    Emoto, M.8
  • 31
    • 84866555540 scopus 로고    scopus 로고
    • Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1
    • Bocci G., Fioravanti A., Orlandi P., Di Desidero T., Natale G., Fanelli G., Viacava P., Naccarato A.G., Francia G., Danesi R. Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1. Neoplasia 2012, 14:833-845.
    • (2012) Neoplasia , vol.14 , pp. 833-845
    • Bocci, G.1    Fioravanti, A.2    Orlandi, P.3    Di Desidero, T.4    Natale, G.5    Fanelli, G.6    Viacava, P.7    Naccarato, A.G.8    Francia, G.9    Danesi, R.10
  • 32
    • 84884313134 scopus 로고    scopus 로고
    • Association between baseline VEGF/sVEGFR-2 and VEGF/TSP-1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer
    • Perroud H.A., Rico M.J., Alasino C.M., Pezzotto S.M., Rozados V.R., Scharovsky O.G. Association between baseline VEGF/sVEGFR-2 and VEGF/TSP-1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer. Indian J. Cancer 2013, 50:115-121.
    • (2013) Indian J. Cancer , vol.50 , pp. 115-121
    • Perroud, H.A.1    Rico, M.J.2    Alasino, C.M.3    Pezzotto, S.M.4    Rozados, V.R.5    Scharovsky, O.G.6
  • 33
    • 84855706050 scopus 로고    scopus 로고
    • Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis
    • Albertsson P., Lennernas B., Norrby K. Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis. APMIS 2012, 120:147-156.
    • (2012) APMIS , vol.120 , pp. 147-156
    • Albertsson, P.1    Lennernas, B.2    Norrby, K.3
  • 34
    • 33645744835 scopus 로고    scopus 로고
    • Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT-cyclophosphamide metronomic chemotherapy
    • Munoz R., Man S., Shaked Y., Lee C.R., Wong J., Francia G., Kerbel R.S. Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT-cyclophosphamide metronomic chemotherapy. Cancer Res. 2006, 66:3386-3391.
    • (2006) Cancer Res. , vol.66 , pp. 3386-3391
    • Munoz, R.1    Man, S.2    Shaked, Y.3    Lee, C.R.4    Wong, J.5    Francia, G.6    Kerbel, R.S.7
  • 36
    • 34347346140 scopus 로고    scopus 로고
    • The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers
    • Gunningham S.P., Currie M.J., Morrin H.R., Tan E.Y., Turley H., Dachs G.U., Watson A.I., Frampton C., Robinson B.A., Fox S.B. The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers. J. Pathol. 2007, 212:335-344.
    • (2007) J. Pathol. , vol.212 , pp. 335-344
    • Gunningham, S.P.1    Currie, M.J.2    Morrin, H.R.3    Tan, E.Y.4    Turley, H.5    Dachs, G.U.6    Watson, A.I.7    Frampton, C.8    Robinson, B.A.9    Fox, S.B.10
  • 37
    • 27144446814 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells
    • Garmy-Susini B., Varner J.A. Circulating endothelial progenitor cells. Br. J. Cancer 2005, 93:855-858.
    • (2005) Br. J. Cancer , vol.93 , pp. 855-858
    • Garmy-Susini, B.1    Varner, J.A.2
  • 40
    • 80051785427 scopus 로고    scopus 로고
    • Thrombospondin-1 short hairpin RNA suppresses tubulointerstitial fibrosis in the kidney of ureteral obstruction by ameliorating peritubular capillary injury
    • Sun D., Ma Y., Han H., Yin Z., Liu C., Feng J., Zhou X., Li X., Xiao A., Yu R. Thrombospondin-1 short hairpin RNA suppresses tubulointerstitial fibrosis in the kidney of ureteral obstruction by ameliorating peritubular capillary injury. Kidney Blood Press. Res. 2012, 35:35-47.
    • (2012) Kidney Blood Press. Res. , vol.35 , pp. 35-47
    • Sun, D.1    Ma, Y.2    Han, H.3    Yin, Z.4    Liu, C.5    Feng, J.6    Zhou, X.7    Li, X.8    Xiao, A.9    Yu, R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.