메뉴 건너뛰기




Volumn 85, Issue 6, 2013, Pages 328-335

Bevacizumab + capecitabine as maintenance therapy after initial bevacizumab + XELOX treatment in previously untreated patients with metastatic colorectal cancer: Phase iii 'stop and go' study results - A turkish oncology group trial

Author keywords

Bevacizumab; Capecitabine; Maintenance therapy; Metastatic colorectal cancer; Oxaliplatin

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CAPECITABINE PLUS OXALIPLATIN; OXALIPLATIN;

EID: 84892147161     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000355914     Document Type: Article
Times cited : (59)

References (27)
  • 2
    • 34948892881 scopus 로고    scopus 로고
    • Spanish Cooperative Group for the Treatment of Digestive Tumors Trial: Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: Final Report of the Spanish Cooperative Group for the treatment of digestive tumors trial
    • Díaz-Rubio E, Tabernero J, Gómez-España A, Massutí B, Sastre J, Chaves M, Abad A, Carrato A, Queralt B, Reina JJ, Maurel J, González- Flores E, Aparicio J, Rivera F, Losa F, Aranda E, Spanish Cooperative Group for the Treatment of Digestive Tumors Trial: Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: final Report of the Spanish Cooperative Group for the treatment of digestive tumors trial. J Clin Oncol 2007; 25: 4224-4230.
    • (2007) J Clin Oncol , vol.25 , pp. 4224-4230
    • Díaz-Rubio, E.1    Tabernero, J.2    Gómez-España, A.3    Massutí, B.4    Sastre, J.5    Chaves, M.6    Abad, A.7    Carrato, A.8    Queralt, B.9    Reina, J.J.10    Maurel, J.11    González- Flores, E.12    Aparicio, J.13    Rivera, F.14    Losa, F.15    Aranda, E.16
  • 4
    • 33845210679 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin (XELOX) versus protracted 5-fluorouracil venous infusion plus oxaliplatin (pvifox) as first-line treatment in advanced colorectal cancer: A GOAM phase II randomized study (FOCA trial)
    • Martoni AA, Pinto C, Di Fabio F, Lelli G, Rojas Llimpe FL, Gentile AL, Mutri V, Ballardini P, Giaquinta S, Piana E: Capecitabine plus oxaliplatin (XELOX) versus protracted 5-fluorouracil venous infusion plus oxaliplatin (pvifox) as first-line treatment in advanced colorectal cancer: a GOAM phase II randomized study (FOCA trial). Eur J Cancer 2006; 42: 3161-3168.
    • (2006) Eur J Cancer , vol.42 , pp. 3161-3168
    • Martoni, A.A.1    Pinto, C.2    Di Fabio, F.3    Lelli, G.4    Rojas Llimpe, F.L.5    Gentile, A.L.6    Mutri, V.7    Ballardini, P.8    Giaquinta, S.9    Piana, E.10
  • 5
    • 34948857445 scopus 로고    scopus 로고
    • AIO Colorectal Study Group: Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: A final report of the AIO colorectal study group
    • Porschen R, Arkenau HT, Kubicka S, Greil R, Seufferlein T, Freier W, Kretzschmar A, Graeven U, Grothey A, Hinke A, Schmiegel W, Schmoll HJ, AIO Colorectal Study Group: Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group. J Clin Oncol 2007; 25: 4217-4223.
    • (2007) J Clin Oncol , vol.25 , pp. 4217-4223
    • Porschen, R.1    Arkenau, H.T.2    Kubicka, S.3    Greil, R.4    Seufferlein, T.5    Freier, W.6    Kretzschmar, A.7    Graeven, U.8    Grothey, A.9    Hinke, A.10    Schmiegel, W.11    Schmoll, H.J.12
  • 6
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J: The biology of VEGF and its receptors. Nat Med 2003; 9: 669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 7
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • Jain RK: Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 2001; 7: 987-989.
    • (2001) Nat Med , vol.7 , pp. 987-989
    • Jain, R.K.1
  • 8
    • 84866152751 scopus 로고    scopus 로고
    • Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: Results of a randomized phase III intergroup study (TML study) (abstract CRA3503)
    • Arnold D, Andre T, Bennouna J, Sastre J, Osterlund PJ, Greil R, Van Cutsem E, Von Moos R, Reyes-Rivera I, Bendahmane B, Kubicka S: Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: results of a randomized phase III intergroup study (TML study) (abstract CRA3503). J Clin Oncol 2012; 30(suppl).
    • (2012) J Clin Oncol , vol.30 SUPPL.
    • Arnold, D.1    Andre, T.2    Bennouna, J.3    Sastre, J.4    Osterlund, P.J.5    Greil, R.6    Van Cutsem, E.7    Von Moos, R.8    Reyes-Rivera, I.9    Bendahmane, B.10    Kubicka, S.11
  • 9
    • 34248173883 scopus 로고    scopus 로고
    • Eastern cooperative oncology group study e3200: Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the eastern cooperative oncology group study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP, Alberts SR, Schwartz MA, Benson AB 3rd, Eastern Cooperative Oncology Group Study E3200: Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007; 25: 1539-1544.
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson III, A.B.8
  • 11
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F, Hurwitz HI, Fehrenbacher L, Meropol NJ, Novotny WF, Lieberman G, Griffing S, Bergsland E: Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003; 21: 60-65.
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3    Meropol, N.J.4    Novotny, W.F.5    Lieberman, G.6    Griffing, S.7    Bergsland, E.8
  • 12
    • 20544471876 scopus 로고    scopus 로고
    • Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
    • Kabbinavar FF, Hambleton J, Mass RD, Hurwitz HI, Bergsland E, Sarkar S: Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 2005; 23: 3706-3712.
    • (2005) J Clin Oncol , vol.23 , pp. 3706-3712
    • Kabbinavar, F.F.1    Hambleton, J.2    Mass, R.D.3    Hurwitz, H.I.4    Bergsland, E.5    Sarkar, S.6
  • 14
    • 56749169353 scopus 로고    scopus 로고
    • Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: Results from a large observational cohort study (BRiTE)
    • Grothey A, Sugrue M, Purdie D, Dong W, Sargent D, Hedrick E, Kozloff M: Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE). J Clin Oncol 2008; 26: 5326-5334.
    • (2008) J Clin Oncol , vol.26 , pp. 5326-5334
    • Grothey, A.1    Sugrue, M.2    Purdie, D.3    Dong, W.4    Sargent, D.5    Hedrick, E.6    Kozloff, M.7
  • 15
    • 70349413045 scopus 로고    scopus 로고
    • Investigators of the BRITE study: Clinical outcomes associated with bevacizumab-containing treatment of metastatic colorectal cancer: The BRITE observational cohort study
    • Kozloff M, Yood MU, Berlin J, Flynn PJ, Kabbinavar FF, Purdie DM, Ashby MA, Dong W, Sugrue MM, Grothey A, Investigators of the BRiTE study: Clinical outcomes associated with bevacizumab-containing treatment of metastatic colorectal cancer: the BRiTE observational cohort study. Oncologist 2009; 14: 862-870.
    • (2009) Oncologist , vol.14 , pp. 862-870
    • Kozloff, M.1    Yood, M.U.2    Berlin, J.3    Flynn, P.J.4    Kabbinavar, F.F.5    Purdie, D.M.6    Ashby, M.A.7    Dong, W.8    Sugrue, M.M.9    Grothey, A.10
  • 16
    • 77956072936 scopus 로고    scopus 로고
    • Clinical outcomes in elderly patients with metastatic colorectal cancer receiving bevacizumab and chemotherapy: Results from the BRiTE observational cohort study
    • Kozloff MF, Berlin J, Flynn PJ, Kabbinavar F, Ashby M, Dong W, Sing AP, Grothey A: Clinical outcomes in elderly patients with metastatic colorectal cancer receiving bevacizumab and chemotherapy: results from the BRiTE observational cohort study. Oncology 2010; 78: 329-339.
    • (2010) Oncology , vol.78 , pp. 329-339
    • Kozloff, M.F.1    Berlin, J.2    Flynn, P.J.3    Kabbinavar, F.4    Ashby, M.5    Dong, W.6    Sing, A.P.7    Grothey, A.8
  • 19
    • 65749088446 scopus 로고    scopus 로고
    • Intermittent oxaliplatin (oxali) administration and time-to-treatment failure (TTF) in metastatic colorectal cancer (mCRC): Final results of the phase III CONcePT trial (abstract 4010)
    • Grothey A, Hart L, Rowland K, Ansari RH, Alberts SR, Chowhan NM, Shpilsky A, Hochster HS: Intermittent oxaliplatin (oxali) administration and time-to-treatment failure (TTF) in metastatic colorectal cancer (mCRC): final results of the phase III CONcePT trial (abstract 4010). J Clin Oncol 2008; 26(suppl 15).
    • (2008) J Clin Oncol , vol.26 SUPPL.15
    • Grothey, A.1    Hart, L.2    Rowland, K.3    Ansari, R.H.4    Alberts, S.R.5    Chowhan, N.M.6    Shpilsky, A.7    Hochster, H.S.8
  • 21
    • 0037425721 scopus 로고    scopus 로고
    • Medical Research Council Colorectal Cancer Group: Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: A multicenter randomized trial
    • Maughan TS, James RD, Kerr DJ, Ledermann JA, Seymour MT, Topham C, McArdle C, Cain D, Stephens RJ, Medical Research Council Colorectal Cancer Group: Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicenter randomized trial. Lancet 2003; 361: 457-464.
    • (2003) Lancet , vol.361 , pp. 457-464
    • Maughan, T.S.1    James, R.D.2    Kerr, D.J.3    Ledermann, J.A.4    Seymour, M.T.5    Topham, C.6    McArdle, C.7    Cain, D.8    Stephens, R.J.9
  • 25
    • 84892159286 scopus 로고    scopus 로고
    • Intermittent versus continuous oxaliplatin-based combination chemotherapy in patients with advanced colorectal cancer: A randomized non-inferiority trial (MRC COIN) (abstract 15LBA)
    • Adams R, Wilson R, Seymour M, Meade AM, Madi A, Cassidy J, Fisher D, Kenny S, Kaplan R, Maughan TS: Intermittent versus continuous oxaliplatin-based combination chemotherapy in patients with advanced colorectal cancer: a randomized non-inferiority trial (MRC COIN) (abstract 15LBA). Eur J Cancer Suppl 2009; 7.
    • (2009) Eur J Cancer Suppl , vol.7
    • Adams, R.1    Wilson, R.2    Seymour, M.3    Meade, A.M.4    Madi, A.5    Cassidy, J.6    Fisher, D.7    Kenny, S.8    Kaplan, R.9    Maughan, T.S.10
  • 26
    • 79956357921 scopus 로고    scopus 로고
    • Randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without, as firs-line treatment of metastatic colorectal cancer: The NORDIC VII study (NCT00145314), by the nordic colorectal cancer biomodulation group (abstract 365)
    • Tveit K, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, Kure E, Ikdahl T, Skovlund E, Christoffersen T: Randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without, as firs-line treatment of metastatic colorectal cancer: the NORDIC VII study (NCT00145314), by the Nordic Colorectal Cancer Biomodulation Group (abstract 365). J Clin Oncol 2011; 29(suppl 4).
    • (2011) J Clin Oncol , vol.29 SUPPL.4
    • Tveit, K.1    Guren, T.2    Glimelius, B.3    Pfeiffer, P.4    Sorbye, H.5    Pyrhonen, S.6    Kure, E.7    Ikdahl, T.8    Skovlund, E.9    Christoffersen, T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.