메뉴 건너뛰기




Volumn 60, Issue 3, 2007, Pages 351-356

Biweekly oxaliplatin plus 1-day infusional fluorouracil/leucovorin followed by metronomic chemotherapy with tegafur/uracil in pretreated metastatic colorectal cancer

Author keywords

Colorectal cancer; Metronomic chemotherapy; Oxaliplatin; Tegafur; UFT

Indexed keywords

BEVACIZUMAB; CETUXIMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; UFT;

EID: 34250637586     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-006-0377-4     Document Type: Article
Times cited : (19)

References (32)
  • 1
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
    • Saltz LB, Cox JV, Blanke C et al (2000) Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group New Engl J Med 343:905-914
    • (2000) Irinotecan Study Group New Engl J Med , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 2
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, Andre T, Achille E et al (2004) FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Onco 22:229-237
    • (2004) J Clin Onco , vol.22 , pp. 229-237
    • Tournigand, C.1    Andre, T.2    Achille, E.3
  • 3
    • 0030888321 scopus 로고    scopus 로고
    • Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-h continuous infusion in pretreated metastatic colorectal cancer
    • de Gramont A, Vignoud J, Tournigand C et al (1997) Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-h continuous infusion in pretreated metastatic colorectal cancer. Eur J Cancer 33:214-219
    • (1997) Eur J Cancer , vol.33 , pp. 214-219
    • De Gramont, A.1    Vignoud, J.2    Tournigand, C.3
  • 4
    • 0032730143 scopus 로고    scopus 로고
    • Multicenter phase II study of bimonthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen
    • Andre T, Bensmaine MA, Louvet C et al (1999) Multicenter phase II study of bimonthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen. J Clin Oncol 17:3560-3568
    • (1999) J Clin Oncol , vol.17 , pp. 3560-3568
    • Andre, T.1    Bensmaine, M.A.2    Louvet, C.3
  • 5
    • 0035032625 scopus 로고    scopus 로고
    • High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7)
    • Maindrault-Goebel F, de Gramont A, Louvet C et al (2001) High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7). Eur J Cancer 37:1000-1005
    • (2001) Eur J Cancer , vol.37 , pp. 1000-1005
    • Maindrault-Goebel, F.1    De Gramont, A.2    Louvet, C.3
  • 6
    • 2642586573 scopus 로고    scopus 로고
    • Oxaliplatin added the simplified bimonthly low dose leucovorin and 5- FU on pretreated advanced colorectal cancer is effective and not affected by different previous 5-FU regimens
    • Hsieh RK, Chao TY, Chen WS et al (2004) Oxaliplatin added the simplified bimonthly low dose leucovorin and 5- FU on pretreated advanced colorectal cancer is effective and not affected by different previous 5-FU regimens. Cancer Invest 22:171-179
    • (2004) Cancer Invest , vol.22 , pp. 171-179
    • Hsieh, R.K.1    Chao, T.Y.2    Chen, W.S.3
  • 7
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF et al (2004) A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 22:23-30
    • (2004) J Clin Oncol , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3
  • 8
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara N, Hillan KJ, Gerber HP et al (2004) Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 3:391-400
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3
  • 9
    • 0034032882 scopus 로고    scopus 로고
    • Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
    • Browder T, Butterfield CE, Kraling BM et al (2000) Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 60:1878-1886
    • (2000) Cancer Res , vol.60 , pp. 1878-1886
    • Browder, T.1    Butterfield, C.E.2    Kraling, B.M.3
  • 10
    • 0034087691 scopus 로고    scopus 로고
    • Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
    • Klement G, Baruchel S, Rak J et al (2000) Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 105:R15-R24
    • (2000) J Clin Invest , vol.105
    • Klement, G.1    Baruchel, S.2    Rak, J.3
  • 11
    • 0034048358 scopus 로고    scopus 로고
    • Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
    • Hanahan D, Bergers G, Bergsland E et al (2000) Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J Clin Invest 105:1045-1047
    • (2000) J Clin Invest , vol.105 , pp. 1045-1047
    • Hanahan, D.1    Bergers, G.2    Bergsland, E.3
  • 12
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel RS, Kamen BA (2004) The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 4:423-436
    • (2004) Nat Rev Cancer , vol.4 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 13
    • 14644446018 scopus 로고    scopus 로고
    • Multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer
    • Pietras K, Hanahan DA (2005) Multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. J Clin Oncol 23:939-952
    • (2005) J Clin Oncol , vol.23 , pp. 939-952
    • Pietras, K.1    Hanahan, D.A.2
  • 14
    • 0035865363 scopus 로고    scopus 로고
    • Refining the target: Chemotherapeutics as antiangiogenics
    • Miller KD, Sweeney CJ, Sledge GW et al (2005) Refining the target: chemotherapeutics as antiangiogenics. J Clin Oncol 19:1195-1206
    • (2005) J Clin Oncol , vol.19 , pp. 1195-1206
    • Miller, K.D.1    Sweeney, C.J.2    Sledge, G.W.3
  • 15
    • 0032795611 scopus 로고    scopus 로고
    • UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice
    • Yonekura K, Basaki Y, Chikahisa L et al (1999) UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice. Clin Cancer Res 5:2185-2191
    • (1999) Clin Cancer Res , vol.5 , pp. 2185-2191
    • Yonekura, K.1    Basaki, Y.2    Chikahisa, L.3
  • 16
    • 1942456762 scopus 로고    scopus 로고
    • Angiogenesis and the efficacy of postoperative administration of UFT in pathologic stage I non-small cell lung cancer
    • Tanaka F, Yanagihara K, Otake Y et al (2004) Angiogenesis and the efficacy of postoperative administration of UFT in pathologic stage I non-small cell lung cancer. Cancer Sci 95:371-376
    • (2004) Cancer Sci , vol.95 , pp. 371-376
    • Tanaka, F.1    Yanagihara, K.2    Otake, Y.3
  • 17
    • 0031060464 scopus 로고    scopus 로고
    • Mechanism-based improvement in the therapeutic selectivity of 5-FU prodrug alone and under conditions of metabolic modulation
    • Rustum YM (1997) Mechanism-based improvement in the therapeutic selectivity of 5-FU prodrug alone and under conditions of metabolic modulation. Oncology (Karger) 1:7-11
    • (1997) Oncology (Karger) , vol.1 , pp. 7-11
    • Rustum, Y.M.1
  • 18
    • 0030833056 scopus 로고    scopus 로고
    • Scientific basis for the combination of tegafur with uracil
    • Maehara Y, Kakeji Y, Ohno S et al (1997) Scientific basis for the combination of tegafur with uracil. Oncology (Huntington) 11:14-21
    • (1997) Oncology (Huntington) , vol.11 , pp. 14-21
    • Maehara, Y.1    Kakeji, Y.2    Ohno, S.3
  • 19
    • 0031840201 scopus 로고    scopus 로고
    • Clinical efficacy of oxaliplatin monotherapy: Phase II trials in advanced colorectal cancer
    • Rougier P (1998) Clinical efficacy of oxaliplatin monotherapy: phase II trials in advanced colorectal cancer. Semin Oncol 25:23-31
    • (1998) Semin Oncol , vol.25 , pp. 23-31
    • Rougier, P.1
  • 20
    • 0036727089 scopus 로고    scopus 로고
    • Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Carmichael J, Popiela T, Radstone D et al (2002) Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20:3617-3627
    • (2002) J Clin Oncol , vol.20 , pp. 3617-3627
    • Carmichael, J.1    Popiela, T.2    Radstone, D.3
  • 21
    • 0036731818 scopus 로고    scopus 로고
    • Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Douillard JY, Hoff PM, Skillings JR et al (2002) Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20:3605-3616
    • (2002) J Clin Oncol , vol.20 , pp. 3605-3616
    • Douillard, J.Y.1    Hoff, P.M.2    Skillings, J.R.3
  • 22
    • 0028820944 scopus 로고
    • A fixed-ratio combination of uracil and Ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer
    • Saltz LB, Leichman CG, Young CW et al (1995) A fixed-ratio combination of uracil and Ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer. Cancer 75:782-785
    • (1995) Cancer , vol.75 , pp. 782-785
    • Saltz, L.B.1    Leichman, C.G.2    Young, C.W.3
  • 23
    • 0141993698 scopus 로고    scopus 로고
    • A cost comparison of oral tegafur plus uracil/folinic acid and parenteral fluorouracil for colorectal cancer in Canada
    • Maroun J, Asche C, Romeyer F et al (2003) A cost comparison of oral tegafur plus uracil/folinic acid and parenteral fluorouracil for colorectal cancer in Canada. Pharmacoeconomics 21:1039-1051
    • (2003) Pharmacoeconomics , vol.21 , pp. 1039-1051
    • Maroun, J.1    Asche, C.2    Romeyer, F.3
  • 24
    • 10844241474 scopus 로고    scopus 로고
    • Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer
    • Feliu J, Vicent JM, Garcia-Giron C et al (2004) Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer. Br J Cancer 91:1758-1762
    • (2004) Br J Cancer , vol.91 , pp. 1758-1762
    • Feliu, J.1    Vicent, J.M.2    Garcia-Giron, C.3
  • 25
    • 0036340246 scopus 로고    scopus 로고
    • Oxaliplatin and UFT combination chemotherapy in patients with metastatic colorectal cancer
    • Kim K, Nam E, Lee NS et al (2002) Oxaliplatin and UFT combination chemotherapy in patients with metastatic colorectal cancer. Am J Clin Oncol 25:354-357
    • (2002) Am J Clin Oncol , vol.25 , pp. 354-357
    • Kim, K.1    Nam, E.2    Lee, N.S.3
  • 26
    • 0034594628 scopus 로고    scopus 로고
    • New Guide-lines to evaluate the response to treatment in solid tumors
    • Therasse P, Arbuck SG, Eisenheuer EA et al (2000) New Guide-lines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 92:205-216
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenheuer, E.A.3
  • 27
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R (1989) Optimal two-stage designs for phase II clinical trials. Control Clin Trials 10:1-10
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 28
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M et al ( 2000) Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol.18:2938-2947
    • (2000) J Clin , vol.18 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3
  • 29
    • 14644398030 scopus 로고    scopus 로고
    • The addition of bevacizumab to FOLFOX4 prolongs survival in relapsed colorectal cancer: Interim data from the ECOG 3200 trial
    • Reddy GK (2005) The addition of bevacizumab to FOLFOX4 prolongs survival in relapsed colorectal cancer: interim data from the ECOG 3200 trial. Clin Colorectal Cancer 4:300-301
    • (2005) Clin Colorectal Cancer , vol.4 , pp. 300-301
    • Reddy, G.K.1
  • 30
    • 0035110959 scopus 로고    scopus 로고
    • Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: A novel target mechanism concept for pharmacokinetic modulating chemotherapy
    • Yoshikawa R, Kusunoki M, Yanagi H et al (2001) Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. Cancer Res 61:1029-1037
    • (2001) Cancer Res , vol.61 , pp. 1029-1037
    • Yoshikawa, R.1    Kusunoki, M.2    Yanagi, H.3
  • 31
    • 0036159485 scopus 로고    scopus 로고
    • Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: A randomised crossover trial in advanced colorectal cancer
    • Borner MM, Schoffski P, de Wit R et al (2002) Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: a randomised crossover trial in advanced colorectal cancer. Eur J Cancer 38:349-358
    • (2002) Eur J Cancer , vol.38 , pp. 349-358
    • Borner, M.M.1    Schoffski, P.2    De Wit, R.3
  • 32
    • 85047698210 scopus 로고    scopus 로고
    • Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity
    • Fischel JL, Formento P, Ciccolini J et al (2002) Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity. Br J Cancer 86:1162-1168
    • (2002) Br J Cancer , vol.86 , pp. 1162-1168
    • Fischel, J.L.1    Formento, P.2    Ciccolini, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.