Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Blankley, Simon ^a   Graham, Christine M ^a   Howes, Ashleigh ^a   Bloom, Chloe I ^a   Berry, Matthew P R ^a,b   Chaussabel, Damien ^c,d   Pascual, Virginia ^c   Banchereau, Jacques ^e   Lipman, Marc ^f   O'Garra, Anne ^a,g  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^c BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^d BENAROYA RESEARCH INSTITUTE   (United States)

^e JACKSON LABORATORY   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; MESSENGER RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; LIPOPEPTIDE; LIPOPOLYSACCHARIDE; PAM(3)CSK(4) PEPTIDE; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ADULT; ARTICLE; BIOINFORMATICS; CELL ISOLATION; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; RNA ISOLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; UPREGULATION; BLOOD; EVALUATION STUDY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; PROCEDURES; TIME;

BLOOD; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; IN VITRO TECHNIQUES; LIPOPEPTIDES; LIPOPOLYSACCHARIDES; MICROARRAY ANALYSIS; NF-KAPPA B; TIME FACTORS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84901381099     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097702     Document Type: Article

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