-
1
-
-
74549167737
-
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
-
[PubMed:20141834]
-
E.J. Park, J.H. Lee, G.Y. Yu, G. He, S.R. Ali, and R.G. Holzer et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression Cell 140 2 2010 197 208 [PubMed:20141834]
-
(2010)
Cell
, vol.140
, Issue.2
, pp. 197-208
-
-
Park, E.J.1
Lee, J.H.2
Yu, G.Y.3
He, G.4
Ali, S.R.5
Holzer, R.G.6
-
2
-
-
72249119475
-
Virally infected mouse liver endothelial cells trigger CD8 + T-cell immunity
-
[PubMed:19737567]
-
M. Kern, A. Popov, K. Scholz, B. Schumak, D. Djandji, and A. Limmer et al. Virally infected mouse liver endothelial cells trigger CD8 + T-cell immunity Gastroenterology 138 1 2010 336 346 [PubMed:19737567]
-
(2010)
Gastroenterology
, vol.138
, Issue.1
, pp. 336-346
-
-
Kern, M.1
Popov, A.2
Scholz, K.3
Schumak, B.4
Djandji, D.5
Limmer, A.6
-
3
-
-
0035053878
-
The lymphoid liver: Considerations on pathways to autoimmune injury
-
H. Kita, I.R. Mackay, J. Van De Water, and M.E. Gershwin The lymphoid liver: considerations on pathways to autoimmune injury Gastroenterology 120 6 2001 1485 1501 [PubMed:11313320] (Pubitemid 32322324)
-
(2001)
Gastroenterology
, vol.120
, Issue.6
, pp. 1485-1501
-
-
Kita, H.1
Mackay, I.R.2
Van De Water, J.3
Gershwin M.Eric4
-
4
-
-
0033936909
-
Essential pathogenetic role for interferon (IFN-)γ in concanavalin A-induced T cell-dependent hepatitis: Exacerbation by exogenous IFN-γ and prevention by IFN-γ receptor-immunoglobulin fusion protein
-
DOI 10.1006/cyto.1999.0561
-
F. Nicoletti, P. Zaccone, M. Xiang, G. Magro, M. Di Mauro, and R. Di Marco et al. Essential pathogenetic role for interferon (IFN-)gamma in concanavalin A-induced T cell-dependent hepatitis: exacerbation by exogenous IFN-gamma and prevention by IFN-gamma receptor-immunoglobulin fusion protein Cytokine 12 4 2000 315 323 [PubMed:10805211] (Pubitemid 30449821)
-
(2000)
Cytokine
, vol.12
, Issue.4
, pp. 315-323
-
-
Nicoletti, F.1
Zaccone, P.2
Xiang, M.3
Magro, G.4
Di Mauro, M.5
Di Marco, R.6
Garotta, G.7
Meroni, P.8
-
5
-
-
0032610467
-
Study on proinflammatory cytokines (IL-1 beta, IL-6, TNF-alpha) and IL-2 in patients with acute hepatitis B
-
[PubMed:10462929]
-
M. Geneva-Popova, and M. Murdjeva Study on proinflammatory cytokines (IL-1 beta, IL-6, TNF-alpha) and IL-2 in patients with acute hepatitis B Folia Med (Plovdiv) 41 1 1999 78 81 [PubMed:10462929]
-
(1999)
Folia Med (Plovdiv)
, vol.41
, Issue.1
, pp. 78-81
-
-
Geneva-Popova, M.1
Murdjeva, M.2
-
6
-
-
0000636654
-
Cyclosporin A protects Balb/c mice from liver damage induced by superan tigen SEB and D-GalN
-
[PubMed:11819431]
-
T. Yin, S.Q. Tong, Y.C. Xie, and D.Y. Lu Cyclosporin A protects Balb/c mice from liver damage induced by superan tigen SEB and D-GalN World J Gastroenterol 5 3 1999 209 212 [PubMed:11819431]
-
(1999)
World J Gastroenterol
, vol.5
, Issue.3
, pp. 209-212
-
-
Yin, T.1
Tong, S.Q.2
Xie, Y.C.3
Lu, D.Y.4
-
7
-
-
0034284306
-
Cyclosporin A and short-term methotrexate versus cyclosporin A as graft versus host disease prophylaxis in patients with severe aplastic anemia given allogeneic bone marrow transplantation from an HLA-identical sibling: Results of a GITMO/EBMT randomized trial
-
F. Locatelli, B. Bruno, M. Zecca, M.T. Van-Lint, S. McCann, and W. Arcese et al. Cyclosporin A and short-term methotrexate versus cyclosporin A as graft versus host disease prophylaxis in patients with severe aplastic anemia given allogeneic bone marrow transplantation from an HLA-identical sibling: results of a GITMO/EBMT randomized trial Blood 96 5 2000 1690 1697 [PubMed:10961865] (Pubitemid 30661050)
-
(2000)
Blood
, vol.96
, Issue.5
, pp. 1690-1697
-
-
Locatelli, F.1
Bruno, B.2
Zecca, M.3
Van-Lint, M.T.4
McCann, S.5
Arcese, W.6
Dallorso, S.7
Di Bartolomeo, P.8
Fagioli, F.9
Locasciulli, A.10
Lawler, M.11
Bacigalupo, A.12
-
8
-
-
0026643743
-
A T cell-dependent experimental liver injury in mice inducible by concanavalin A
-
[PubMed:1634608]
-
G. Tiegs, J. Hentschel, and A. Wendel A T cell-dependent experimental liver injury in mice inducible by concanavalin A J Clin Invest 90 1 1992 196 203 [PubMed:1634608]
-
(1992)
J Clin Invest
, vol.90
, Issue.1
, pp. 196-203
-
-
Tiegs, G.1
Hentschel, J.2
Wendel, A.3
-
9
-
-
0028300351
-
T cell activation-associated hepatic injury: Mediation by tumor necrosis factors and protection by interleukin 6
-
H. Mizuhara, E. O'Neill, N. Seki, T. Ogawa, C. Kusunoki, and K. Otsuka et al. T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6 J Exp Med 179 5 1994 1529 1537 [PubMed:8163936] (Pubitemid 24129570)
-
(1994)
Journal of Experimental Medicine
, vol.179
, Issue.5
, pp. 1529-1537
-
-
Mizuhara, H.1
O'Neill, E.2
Seki, N.3
Ogawa, T.4
Kusunoki, C.5
Otsuka, K.6
Satoh, S.7
Niwa, M.8
Senoh, H.9
Fujiwara, H.10
-
10
-
-
73349100022
-
SOCS3 in T and NKT cells negatively regulates cytokine production and ameliorates ConA-induced hepatitis
-
[PubMed:19915050]
-
M. Nakaya, M. Hashimoto, R. Nakagawa, Y. Wakabayashi, T. Ishizaki, and I. Takada et al. SOCS3 in T and NKT cells negatively regulates cytokine production and ameliorates ConA-induced hepatitis J Immunol 183 11 2009 7047 7053 [PubMed:19915050]
-
(2009)
J Immunol
, vol.183
, Issue.11
, pp. 7047-7053
-
-
Nakaya, M.1
Hashimoto, M.2
Nakagawa, R.3
Wakabayashi, Y.4
Ishizaki, T.5
Takada, I.6
-
11
-
-
79951807377
-
Reciprocal changes of naive and effector/memory CD8 + T lymphocytes in chronic hepatitis B virus infection
-
[PubMed:21319976]
-
P. Carotenuto, A. Artsen, A.D. Osterhaus, and O. Pontesilli Reciprocal changes of naive and effector/memory CD8 + T lymphocytes in chronic hepatitis B virus infection Viral Immunol 24 1 2011 27 33 [PubMed:21319976]
-
(2011)
Viral Immunol
, vol.24
, Issue.1
, pp. 27-33
-
-
Carotenuto, P.1
Artsen, A.2
Osterhaus, A.D.3
Pontesilli, O.4
-
12
-
-
34548459868
-
Structure and function of Toll receptors and their ligands
-
[PubMed:17362201]
-
N.J. Gay, and M. Gangloff Structure and function of Toll receptors and their ligands Annu Rev Biochem 76 2007 141 165 [PubMed:17362201]
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 141-165
-
-
Gay, N.J.1
Gangloff, M.2
-
13
-
-
47149105036
-
Toll-like receptors and adaptor molecules in liver disease: Update
-
DOI 10.1002/hep.22306
-
E. Seki, and D.A. Brenner Toll-like receptors and adaptor molecules in liver disease: update Hepatology 48 1 2008 322 335 [PubMed:18506843] (Pubitemid 351975556)
-
(2008)
Hepatology
, vol.48
, Issue.1
, pp. 322-335
-
-
Seki, E.1
Brenner, D.A.2
-
14
-
-
77956268723
-
MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis
-
[PubMed:20696131]
-
K. Ojiro, H. Ebinuma, N. Nakamoto, K. Wakabayashi, Y. Mikami, and Y. Ono et al. MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis Biochem Biophys Res Commun 399 4 2010 744 749 [PubMed:20696131]
-
(2010)
Biochem Biophys Res Commun
, vol.399
, Issue.4
, pp. 744-749
-
-
Ojiro, K.1
Ebinuma, H.2
Nakamoto, N.3
Wakabayashi, K.4
Mikami, Y.5
Ono, Y.6
-
15
-
-
80051882006
-
Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
-
[PubMed:21784973]
-
J. Xu, X. Zhang, M. Monestier, N.L. Esmon, and C.T. Esmon Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury J Immunol 187 5 2011 2626 2631 [PubMed:21784973]
-
(2011)
J Immunol
, vol.187
, Issue.5
, pp. 2626-2631
-
-
Xu, J.1
Zhang, X.2
Monestier, M.3
Esmon, N.L.4
Esmon, C.T.5
-
16
-
-
0036679733
-
It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation
-
DOI 10.1016/S1471-4906(02)02264-0, PII S1471490602022640
-
L.P. Kane, J. Lin, and A. Weiss It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation Trends Immunol 23 8 2002 413 420 [PubMed:12133805] (Pubitemid 34804638)
-
(2002)
Trends in Immunology
, vol.23
, Issue.8
, pp. 413-420
-
-
Kane, L.P.1
Lin, J.2
Weiss, A.3
-
17
-
-
70349303969
-
Inflammatory regulation by TLR3 in acute hepatitis
-
[PubMed:19710451]
-
X. Xiao, P. Zhao, D. Rodriguez-Pinto, D. Qi, O. Henegariu, and L. Alexopoulou et al. Inflammatory regulation by TLR3 in acute hepatitis J Immunol 183 6 2009 3712 3719 [PubMed:19710451]
-
(2009)
J Immunol
, vol.183
, Issue.6
, pp. 3712-3719
-
-
Xiao, X.1
Zhao, P.2
Rodriguez-Pinto, D.3
Qi, D.4
Henegariu, O.5
Alexopoulou, L.6
-
18
-
-
0033030983
-
Progressive liver functional impairment is associated with an increase in AST/ALT ratio
-
DOI 10.1023/A:1026609231094
-
E. Giannini, F. Botta, A. Fasoli, P. Ceppa, D. Risso, and P.B. Lantieri et al. Progressive liver functional impairment is associated with an increase in AST/ALT ratio Dig Dis Sci 44 6 1999 1249 1253 [PubMed:10389705] (Pubitemid 29297237)
-
(1999)
Digestive Diseases and Sciences
, vol.44
, Issue.6
, pp. 1249-1253
-
-
Giannini, E.1
Botta, F.2
Fasoli, A.3
Ceppa, P.4
Risso, D.5
Lantieri, P.B.6
Celle, G.7
Testa, R.8
-
19
-
-
0034888894
-
Protective effects of cyclosporine A on T-cell dependent ConA-induced liver injury in Kunming mice
-
X.L. Zhang, Q.Z. Quan, Z.Q. Sun, Y.J. Wang, X.L. Jiang, and D. Wang et al. Protective effects of cyclosporine A on T-cell dependent ConA-induced liver injury in Kunming mice World J Gastroenterol 7 4 2001 569 571 [PubMed:11819832] (Pubitemid 32780674)
-
(2001)
World Journal of Gastroenterology
, vol.7
, Issue.4
, pp. 569-571
-
-
Zhang, X.-L.1
Quan, Q.-Z.2
Sun, Z.-Q.3
Wang, Y.-J.4
Jiang, X.-L.5
Wang, D.6
Li, W.-B.7
-
20
-
-
33846642114
-
The role of MAPK in Kupffer cell Toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage
-
DOI 10.1002/jcp.20860
-
B.M. Thobe, M. Frink, F. Hildebrand, M.G. Schwacha, W.J. Hubbard, and M.A. Choudhry et al. The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage J Cell Physiol 210 3 2007 667 675 [PubMed:17117477] (Pubitemid 46185036)
-
(2007)
Journal of Cellular Physiology
, vol.210
, Issue.3
, pp. 667-675
-
-
Thobe, B.M.1
Frink, M.2
Hildebrand, F.3
Schwacha, M.G.4
Hubbard, W.J.5
Choudhry, M.A.6
Chaudry, I.H.7
-
21
-
-
0036084728
-
Role of toll-like receptors in changes in gene expression and NF-κB activation in mouse hepatocytes stimulated with lipopolysaccharide
-
DOI 10.1128/IAI.70.7.3433-3442.2002
-
S. Liu, D.J. Gallo, A.M. Green, D.L. Williams, X. Gong, and R.A. Shapiro et al. Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide Infect Immun 70 7 2002 3433 3442 [PubMed:12065483] (Pubitemid 34665980)
-
(2002)
Infection and Immunity
, vol.70
, Issue.7
, pp. 3433-3442
-
-
Liu, S.1
Gallo, D.J.2
Green, A.M.3
Williams, D.L.4
Gong, X.5
Shapiro, R.A.6
Gambotto, A.A.7
Humphris, E.L.8
Vodovotz, Y.9
Billiar, T.R.10
-
22
-
-
36348997503
-
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9
-
DOI 10.1002/hep.21867
-
A. Watanabe, A. Hashmi, D.A. Gomes, T. Town, A. Badou, and R.A. Flavell et al. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9 Hepatology 46 5 2007 1509 1518 [PubMed:17705260] (Pubitemid 350155533)
-
(2007)
Hepatology
, vol.46
, Issue.5
, pp. 1509-1518
-
-
Watanabe, A.1
Hashmi, A.2
Gomes, D.A.3
Town, T.4
Badou, A.5
Flavell, R.A.6
Mehal, W.Z.7
-
23
-
-
32544446183
-
Interferon γ accelerates NF-κB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction
-
DOI 10.1136/jcp.2004.023507
-
K. Harada, K. Isse, and Y. Nakanuma Interferon gamma accelerates NF-kappaB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction J Clin Pathol 59 2 2006 184 190 [PubMed:16443736] (Pubitemid 43235585)
-
(2006)
Journal of Clinical Pathology
, vol.59
, Issue.2
, pp. 184-190
-
-
Harada, K.1
Isse, K.2
Nakanuma, Y.3
-
24
-
-
34447338577
-
The role of CD11c+ hepatic dendritic cells in the induction of innate immune responses
-
DOI 10.1111/j.1365-2249.2007.03419.x
-
S.A. Shu, Z.X. Lian, Y.H. Chuang, G.X. Yang, Y. Moritoki, and S.S. Comstock et al. The role of CD11c(+) hepatic dendritic cells in the induction of innate immune responses Clin Exp Immunol 149 2 2007 335 343 [PubMed:17521321] (Pubitemid 47063054)
-
(2007)
Clinical and Experimental Immunology
, vol.149
, Issue.2
, pp. 335-343
-
-
Shu, S.-A.1
Lian, Z.-X.2
Chuang, Y.-H.3
Yang, G.-X.4
Moritoki, Y.5
Comstock, S.S.6
Zhong, R.-Q.7
Ansari, A.A.8
Liu, Y.-J.9
Gershwin, M.E.10
-
25
-
-
32944464648
-
Pathogen recognition and innate immunity
-
DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
-
S. Akira, S. Uematsu, and O. Takeuchi Pathogen recognition and innate immunity Cell 124 4 2006 783 801 [PubMed:16497588] (Pubitemid 43261452)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
26
-
-
0036785630
-
Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice
-
[PubMed:12244183]
-
E. Seki, H. Tsutsui, N.M. Tsuji, N. Hayashi, K. Adachi, and H. Nakano et al. Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice J Immunol 169 7 2002 3863 3868 [PubMed:12244183]
-
(2002)
J Immunol
, vol.169
, Issue.7
, pp. 3863-3868
-
-
Seki, E.1
Tsutsui, H.2
Tsuji, N.M.3
Hayashi, N.4
Adachi, K.5
Nakano, H.6
-
27
-
-
33646539166
-
Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver
-
DOI 10.1002/hep.21138
-
T. Gustot, A. Lemmers, C. Moreno, N. Nagy, E. Quertinmont, and C. Nicaise et al. Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver Hepatology 43 5 2006 989 1000 [PubMed:16628628] (Pubitemid 43724624)
-
(2006)
Hepatology
, vol.43
, Issue.5
, pp. 989-1000
-
-
Gustot, T.1
Lemmers, A.2
Moreno, C.3
Nagy, N.4
Quertinmont, E.5
Nicaise, C.6
Franchimont, D.7
Louis, H.8
Deviere, J.9
Le Moine, O.10
-
28
-
-
20244373939
-
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
-
DOI 10.1084/jem.20042614
-
A. Tsung, R. Sahai, H. Tanaka, A. Nakao, M.P. Fink, and M.T. Lotze et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion J Exp Med 201 7 2005 1135 1143 [PubMed:15795240] (Pubitemid 40524681)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.7
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
Nakao, A.4
Fink, M.P.5
Lotze, M.T.6
Yang, H.7
Li, J.8
Tracey, K.J.9
Geller, D.A.10
Billiar, T.R.11
-
29
-
-
0036785557
-
MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: No role for either in macrophage listericidal activity
-
[PubMed:12244184]
-
B.T. Edelson, and E.R. Unanue MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity J Immunol 169 7 2002 3869 3875 [PubMed:12244184]
-
(2002)
J Immunol
, vol.169
, Issue.7
, pp. 3869-3875
-
-
Edelson, B.T.1
Unanue, E.R.2
-
30
-
-
79551633839
-
Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke
-
[PubMed:20842165]
-
G. Ziegler, D. Freyer, D. Harhausen, U. Khojasteh, W. Nietfeld, and G. Trendelenburg Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke J Cereb Blood Flow Metab 31 2 2011 757 766 [PubMed:20842165]
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, Issue.2
, pp. 757-766
-
-
Ziegler, G.1
Freyer, D.2
Harhausen, D.3
Khojasteh, U.4
Nietfeld, W.5
Trendelenburg, G.6
-
31
-
-
25444515154
-
Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance
-
DOI 10.1111/j.1365-2567.2005.02211.x
-
A.H. Dalpke, M.D. Lehner, T. Hartung, and K. Heeg Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance Immunology 116 2 2005 203 212 [PubMed:16162269] (Pubitemid 41368662)
-
(2005)
Immunology
, vol.116
, Issue.2
, pp. 203-212
-
-
Dalpke, A.H.1
Lehner, M.D.2
Hartung, T.3
Heeg, K.4
-
32
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
DOI 10.1038/35099560
-
L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 6857 2001 732 738 [PubMed:11607032] (Pubitemid 33009951)
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
|