-
1
-
-
34548148686
-
Age-and gender-specific reference values of estimated GFR in Caucasians: The Nijmegen Biomedical Study
-
Wetzels JF, Kiemeney LA, Swinkels DW, Willems HL, den Heijer M. Age-and gender-specific reference values of estimated GFR in Caucasians: the Nijmegen Biomedical Study. Kidney Int 2007;72:632-637.
-
(2007)
Kidney Int
, vol.72
, pp. 632-637
-
-
Wetzels, J.F.1
Kiemeney, L.A.2
Swinkels, D.W.3
Willems, H.L.4
Heijer, M.D.5
-
2
-
-
38149099845
-
Renal function and functional reserve in healthy elderly individuals
-
Esposito C, Plati A, Mazzullo T, et al. Renal function and functional reserve in healthy elderly individuals. J Nephrol 2007;20:617-625.
-
(2007)
J Nephrol
, vol.20
, pp. 617-625
-
-
Esposito, C.1
Plati, A.2
Mazzullo, T.3
-
3
-
-
76549236600
-
Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males
-
Davies DF, Shock NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest 1950;29:496-507.
-
(1950)
J Clin Invest
, vol.29
, pp. 496-507
-
-
Davies, D.F.1
Shock, N.W.2
-
4
-
-
0141674882
-
Determinants of glomerular hypofiltration in aging humans
-
Hoang K, Tan JC, Derby G, et al. Determinants of glomerular hypofiltration in aging humans. Kidney Int 2003;64:1417-1424.
-
(2003)
Kidney Int
, vol.64
, pp. 1417-1424
-
-
Hoang, K.1
Tan, J.C.2
Derby, G.3
-
5
-
-
50849133886
-
The aging kidney
-
Zhou XJ, Rakheja D, Yu X, Saxena R, Vaziri ND, Silva FG. The aging kidney. Kidney Int 2008;74:710-720.
-
(2008)
Kidney Int
, vol.74
, pp. 710-720
-
-
Zhou, X.J.1
Rakheja, D.2
Yu, X.3
Saxena, R.4
Vaziri, N.D.5
Silva, F.G.6
-
7
-
-
0037336035
-
Morphometric study of arterioles and glomeruli in the aging kidney suggests focal loss of autoregulation
-
Hill GS, Heudes D, Bariety J. Morphometric study of arterioles and glomeruli in the aging kidney suggests focal loss of autoregulation. Kidney Int 2003;63:1027-1036.
-
(2003)
Kidney Int
, vol.63
, pp. 1027-1036
-
-
Hill, G.S.1
Heudes, D.2
Bariety, J.3
-
9
-
-
84942506629
-
Age and the renin-aldosterone system
-
Noth RH, Lassman MN, Tan SY, Fernandez-Cruz A Jr, Mulrow PJ. Age and the renin-aldosterone system. Arch Intern Med 1977;137:1414-1417.
-
(1977)
Arch Intern Med
, vol.137
, pp. 1414-1417
-
-
Noth, R.H.1
Lassman, M.N.2
Tan, S.Y.3
Fernandez-Cruz Jr., A.4
Mulrow, P.J.5
-
11
-
-
0028793786
-
Aldosterone responses to hyperkalemia in healthy elderly humans
-
Mulkerrin E, Epstein FH, Clark BA. Aldosterone responses to hyperkalemia in healthy elderly humans. J Am Soc Nephrol 1995;6:1459-1462.
-
(1995)
J Am Soc Nephrol
, vol.6
, pp. 1459-1462
-
-
Mulkerrin, E.1
Epstein, F.H.2
Clark, B.A.3
-
12
-
-
0029034602
-
Down-regulation of the intrarenal renin-angiotensin system in the aging rat
-
Jung FF, Kennefick TM, Ingelfinger JR, Vora JP, Anderson S. Down-regulation of the intrarenal renin-angiotensin system in the aging rat. J Am Soc Nephrol 1995;5:1573-1580.
-
(1995)
J Am Soc Nephrol
, vol.5
, pp. 1573-1580
-
-
Jung, F.F.1
Kennefick, T.M.2
Ingelfinger, J.R.3
Vora, J.P.4
Anderson, S.5
-
13
-
-
0028122676
-
Glomerular adaptations with normal aging and with long-term converting enzyme inhibition in rats
-
Anderson S, Rennke HG, Zatz R. Glomerular adaptations with normal aging and with long-term converting enzyme inhibition in rats. Am J Physiol 1994;267:F35-F43.
-
(1994)
Am J Physiol
, vol.267
-
-
Anderson, S.1
Rennke, H.G.2
Zatz, R.3
-
14
-
-
0023039441
-
Renin-angiotensin system, converting-enzyme inhibition and kidney function in aging female rats
-
Corman B, Michel JB. Renin-angiotensin system, converting-enzyme inhibition and kidney function in aging female rats. Am J Physiol 1986;251:R450-R455.
-
(1986)
Am J Physiol
, vol.251
-
-
Corman, B.1
Michel, J.B.2
-
15
-
-
0030905968
-
Ageing and the renin-angiotensin system
-
Anderson S. Ageing and the renin-angiotensin system. Nephrol Dial Transplant 1997;12:1093-1094.
-
(1997)
Nephrol Dial Transplant
, vol.12
, pp. 1093-1094
-
-
Anderson, S.1
-
16
-
-
0017240384
-
Age as a determinant of renal sodium conservation in normal man
-
Epstein M, Hollenberg NK. Age as a determinant of renal sodium conservation in normal man. J Lab Clin Med 1976;87:411-417.
-
(1976)
J Lab Clin Med
, vol.87
, pp. 411-417
-
-
Epstein, M.1
Hollenberg, N.K.2
-
17
-
-
48549095189
-
Renal senescence in 2008: Progress and challenges
-
Zhou XJ, Saxena R, Liu Z, Vaziri ND, Silva FG. Renal senescence in 2008: progress and challenges. Int Urol Nephrol 2008;40:823-839.
-
(2008)
Int Urol Nephrol
, vol.40
, pp. 823-839
-
-
Zhou, X.J.1
Saxena, R.2
Liu, Z.3
Vaziri, N.D.4
Silva, F.G.5
-
18
-
-
33746570114
-
Transtubular potassium concentration gradient: Comparison between healthy old people and chronic renal failure patients
-
Musso C, Liakopoulos V, De Miguel R, Imperiali N, Algranati L. Transtubular potassium concentration gradient: comparison between healthy old people and chronic renal failure patients. Int Urol Nephrol 2006;38:387-390.
-
(2006)
Int Urol Nephrol
, vol.38
, pp. 387-390
-
-
Musso, C.1
Liakopoulos, V.2
de Miguel, R.3
Imperiali, N.4
Algranati, L.5
-
20
-
-
0030370126
-
Renal interstitial sclerosis in aging: Effects of enalapril and nifedipine
-
Inserra F, Romano LA, de Cavanagh EM, Ercole L, Ferder LF, Gomez RA. Renal interstitial sclerosis in aging: effects of enalapril and nifedipine. J Am Soc Nephrol 1996;7:676-680.
-
(1996)
J Am Soc Nephrol
, vol.7
, pp. 676-680
-
-
Inserra, F.1
Romano, L.A.2
de Cavanagh, E.M.3
Ercole, L.4
Ferder, L.F.5
Gomez, R.A.6
-
22
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004;303:2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
23
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004;23:2369-2380.
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
-
24
-
-
84872008953
-
Sirtuins and renal diseases: Relationship with aging and diabetic nephropathy
-
Kitada M, Kume S, Takeda-Watanabe A, Kanasaki K, Koya D. Sirtuins and renal diseases: relationship with aging and diabetic nephropathy. Clin Sci (Lond) 2013;124:153-164.
-
(2013)
Clin Sci (Lond)
, vol.124
, pp. 153-164
-
-
Kitada, M.1
Kume, S.2
Takeda-Watanabe, A.3
Kanasaki, K.4
Koya, D.5
-
25
-
-
77951165669
-
Sirt1 activation protects the mouse renal medulla from oxidative injury
-
He W, Wang Y, Zhang MZ, et al. Sirt1 activation protects the mouse renal medulla from oxidative injury. J Clin Invest 2010;120:1056-1068.
-
(2010)
J Clin Invest
, vol.120
, pp. 1056-1068
-
-
He, W.1
Wang, Y.2
Zhang, M.Z.3
-
26
-
-
84872778565
-
Age-associated molecular changes in the kidney in aged mice
-
Lim JH, Kim EN, Kim MY, et al. Age-associated molecular changes in the kidney in aged mice. Oxid Med Cell Longev 2012;2012:171383.
-
(2012)
Oxid Med Cell Longev
, pp. 171383
-
-
Lim, J.H.1
Kim, E.N.2
Kim, M.Y.3
-
27
-
-
46249095235
-
SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells
-
Miyazaki R, Ichiki T, Hashimoto T, et al. SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2008;28:1263-1269.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1263-1269
-
-
Miyazaki, R.1
Ichiki, T.2
Hashimoto, T.3
-
28
-
-
84898020293
-
Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice
-
Dec 19 [Epub]
-
Gao P, Xu TT, Lu J, et al. Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice. J Mol Med (Berl) 2013 Dec 19 [Epub]. http://dx.doi.org/10.1007/s00109-013-1111-4.
-
(2013)
J Mol Med (Berl)
-
-
Gao, P.1
Xu, T.T.2
Lu, J.3
-
29
-
-
77952737389
-
Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease
-
Dilauro M, Zimpelmann J, Robertson SJ, Genest D, Burns KD. Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease. Am J Physiol Renal Physiol 2010;298:F1523-F1532.
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Dilauro, M.1
Zimpelmann, J.2
Robertson, S.J.3
Genest, D.4
Burns, K.D.5
-
30
-
-
84862625049
-
Angiotensin-(1-7) attenuates diabetic nephropathy in Zucker diabetic fatty rats
-
Giani JF, Burghi V, Veiras LC, et al. Angiotensin-(1-7) attenuates diabetic nephropathy in Zucker diabetic fatty rats. Am J Physiol Renal Physiol 2012;302:F1606-F1615.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
-
-
Giani, J.F.1
Burghi, V.2
Veiras, L.C.3
-
31
-
-
84900557163
-
Angiotensin 1-7 mediates renoprotection against diabetic nephropathy by reducing oxidative stress, inf lammation and lipotoxicity
-
Feb 19 [Epub]
-
Mori J, Patel VB, Ramprasath T, Alrob OA, et al. Angiotensin 1-7 mediates renoprotection against diabetic nephropathy by reducing oxidative stress, inf lammation and lipotoxicity. Am J Physiol Renal Physiol 2014 Feb 19 [Epub]. http://dx.doi.org/10.1152/ajprenal.00655.2013.
-
(2014)
Am J Physiol Renal Physiol
-
-
Mori, J.1
Patel, V.B.2
Ramprasath, T.3
Alrob, O.A.4
-
32
-
-
65349128571
-
Disruption of the Ang II type 1 receptor promotes longevity in mice
-
Benigni A, Corna D, Zoja C, et al. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 2009;119:524-530.
-
(2009)
J Clin Invest
, vol.119
, pp. 524-530
-
-
Benigni, A.1
Corna, D.2
Zoja, C.3
-
33
-
-
0038718692
-
Enalapril and losartan attenuate mitochondrial dysfunction in aged rats
-
de Cavanagh EM, Piotrkowski B, Basso N, et al. Enalapril and losartan attenuate mitochondrial dysfunction in aged rats. FASEB J 2003;17:1096-1098.
-
(2003)
FASEB J
, vol.17
, pp. 1096-1098
-
-
de Cavanagh, E.M.1
Piotrkowski, B.2
Basso, N.3
-
34
-
-
0038129781
-
Model of robust induction of glomerulosclerosis in mice: Importance of genetic background
-
Ma LJ, Fogo AB. Model of robust induction of glomerulosclerosis in mice: importance of genetic background. Kidney Int 2003;64:350-355.
-
(2003)
Kidney Int
, vol.64
, pp. 350-355
-
-
Ma, L.J.1
Fogo, A.B.2
-
35
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H, et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 1997;390:45-51.
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-o, M.1
Matsumura, Y.2
Aizawa, H.3
-
36
-
-
79959850992
-
Klotho and the aging process
-
Kuro-o M. Klotho and the aging process. Korean J Intern Med 2011;26:113-122.
-
(2011)
Korean J Intern Med
, vol.26
, pp. 113-122
-
-
Kuro-o, M.1
-
37
-
-
0034810211
-
Severely reduced production of klotho in human chronic renal failure kidney
-
Koh N, Fujimori T, Nishiguchi S, et al. Severely reduced production of klotho in human chronic renal failure kidney. Biochem Biophys Res Commun 2001;280:1015-1020.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 1015-1020
-
-
Koh, N.1
Fujimori, T.2
Nishiguchi, S.3
-
38
-
-
69949085836
-
Klotho and aging
-
Kuro-o M. Klotho and aging. Biochim Biophys Acta 2009;1790:1049-1058.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1049-1058
-
-
Kuro-o, M.1
-
39
-
-
0036235099
-
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage
-
Mitani H, Ishizaka N, Aizawa T, et al. In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage. Hypertension 2002;39:838-843.
-
(2002)
Hypertension
, vol.39
, pp. 838-843
-
-
Mitani, H.1
Ishizaka, N.2
Aizawa, T.3
-
40
-
-
0142134263
-
Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat
-
Saito K, Ishizaka N, Mitani H, Ohno M, Nagai R. Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat. FEBS Lett 2003;551:58-62.
-
(2003)
FEBS Lett
, vol.551
, pp. 58-62
-
-
Saito, K.1
Ishizaka, N.2
Mitani, H.3
Ohno, M.4
Nagai, R.5
-
41
-
-
84887302965
-
Effect of renin-angiotensin system blockade on soluble Klotho in patients with type 2 diabetes, systolic hypertension, and albuminuria
-
Karalliedde J, Maltese G, Hill B, Viberti G, Gnudi L. Effect of renin-angiotensin system blockade on soluble Klotho in patients with type 2 diabetes, systolic hypertension, and albuminuria. Clin J Am Soc Nephrol 2013;8:1899-1905.
-
(2013)
Clin J Am Soc Nephrol
, vol.8
, pp. 1899-1905
-
-
Karalliedde, J.1
Maltese, G.2
Hill, B.3
Viberti, G.4
Gnudi, L.5
-
42
-
-
79952167540
-
Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy
-
Yoon HE, Ghee JY, Piao S, et al. Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy. Nephrol Dial Transplant 2011;26:800-813.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 800-813
-
-
Yoon, H.E.1
Ghee, J.Y.2
Piao, S.3
-
43
-
-
68549097866
-
Established and newly proposed mechanisms of chronic cyclosporine nephropathy
-
Yoon HE, Yang CW. Established and newly proposed mechanisms of chronic cyclosporine nephropathy. Korean J Intern Med 2009;24:81-92.
-
(2009)
Korean J Intern Med
, vol.24
, pp. 81-92
-
-
Yoon, H.E.1
Yang, C.W.2
|