Demethylation within the proximal promoter region of human estrogen receptor alpha gene correlates with its enhanced expression: Implications for female bias in lupus

Molecular Immunology

Volumn 61, Issue 1, 2014, Pages 28-37

  Liu, Hong Wen ^a,b,c   Lin, Hui Li ^c,d   Yen, Jeng Hsien ^b,c   Tsai, Wen Chan ^b,c   Chiou, Shyh Shin ^b,c   Chang, Jan Gowth ^b,c   Ou, Tsan Teng ^b   Wu, Cheng Chin ^b   Chao, Nien Chan ^b  

^a TIAN SHENG MEMORIAL HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d MEIHO UNIVERSITY   (Taiwan)

Author keywords

Estrogen; Estrogen receptor alpha; Female bias; Promoter demethylation; Rheumatoid arthritis; Systemic lupus erythematosus

Indexed keywords

DNA; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DISEASE ACTIVITY; FEMALE; FLOW CYTOMETRY; GENE AMPLIFICATION; GENE EXPRESSION; GOUT; HUMAN; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; RHEUMATOID ARTHRITIS; SLEDAI; SYSTEMIC LUPUS ERYTHEMATOSUS; TRANSCRIPTION INITIATION SITE; UPREGULATION; YOUNG ADULT;

ESTROGEN; ESTROGEN RECEPTOR ALPHA; FEMALE BIAS; PROMOTER DEMETHYLATION; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ACETYLATION; ADOLESCENT; ADULT; ARTHRITIS, RHEUMATOID; BASE SEQUENCE; CELLS, CULTURED; CHILD; CPG ISLANDS; DNA METHYLATION; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION; HISTONES; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84901372294     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2014.05.002     Document Type: Article

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