Osteopontin and Systemic Lupus Erythematous association: A probable gene-gender interaction

PLoS ONE

Volumn 3, Issue 3, 2008, Pages

  Han, Shizhong ^a   Guthridge, Joel M ^a   Harley, Isaac T W ^a   Sestak, Andrea L ^a   Kim Howard, Xana ^a   Kaufman, Kenneth M ^a,b,c   Namjou, Bahram ^a   Deshmukh, Harshal ^a   Bruner, Gail ^a   Espinoza, Luis R ^d   Gilkeson, Gary S ^e   Harley, John B ^a,b,c   James, Judith A ^a,c   Nath, Swapan K ^a,c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; OSTEOPONTIN; THYMINE;

AFRICAN AMERICAN; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DNA POLYMORPHISM; EUROPEAN AMERICAN; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENOME ANALYSIS; HAPLOTYPE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; POPULATION BASED CASE CONTROL STUDY; POPULATION GENETICS; POPULATION STRUCTURE; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; ALLELE; GENETICS; PHYSIOLOGY;

ALLELES; FEMALE; GENE FREQUENCY; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; OSTEOPONTIN; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS;

EID: 46149104382     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001757     Document Type: Article

References (40)

1. Nath SK, Kilpatrick J, Harley, JB (2004) Genetics of human systemic lupus crythematosus: the emerging picture. Curr Opin Immunol 16: 794-800.
2. Sestak AL, Nath SK, Sawalha AH, Harley JB (2007) Current status of lupus genetics. Arthritis Res Ther 9: 210.
3. Prokunina L, Castillejo-Lopez C, Oberg F, Gunnarsson I, Berg L, et al. (2002) A regulatory polymorphism, in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 32: 666-669.
4. Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, et al. (2004) Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 75: 504-507.
5. Kaufman KM, Kelly JA, Herring BJ, Adler AJ, Glenn SB, et al. (2006) Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus. Arthritis Rheum 54: 2533-2540.
6. Graham DS, Wong AK, McHugh NJ, Whittaker JC, Vyse TJ (2006) Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study. Hum Mol Genet 15: 3195-3205.
7. Graham RP, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, et al. (2007) Three functional variants of IFN regulatory factor 5 IRF5; define risk and protective haplotypes for human lupus. Proc Natl Acad Sci 104: 6758-6763.
8. O'Regan AW, Nau GJ, Chopp GL, Berman JS (2000) Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks. Immunol Today 21: 475-478.
9. Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Janssen M, et al. (2000) Eta-1(osteopontin): an early component of typte-1(cell-mediated) immunity. Science 287: 860-864.
10. Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, et al. (2007) Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol 8: 74-83.
11. Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, et al. (2006) Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol 75: 498-506.
12. Katagiri Y, Mori K, Hara T, Tanaka K, Murakami M, et al. (1995) Functional analysis of the osteopontin molecule. Ann N Y Acad Sci 760: 371-374.
13. Wong CK, Lit LC, Tam LS, Li EK, Lam CW (2005) Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus. Rheumatology (Oxford) 44: 602-606.
14. Miyazaki T, Ono M, Qu WM, Zhang MC, Mori S, et al. (2005) Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice. Eur J Immunol 355: 1510-1520.
15. Forton AC, Petri MA, Goldman D, Sullivan KE (2002) An osteopontin (SPP1) polymorphism is associated with systemic lupus erythematosus. Hum Mutat 19:459.
16. Chiocchetti A, Indelicato M, Bensi T, Mesturini R, Giordano M, et al. (2004) High levels of osteopontin associated with polymorphisms in its gene are a risk factor for development of autoimmunity/ lymphoproliferation. Blood 103: 1376-1382.
17. D'Alfonso S, Barizzone N, Giordano M, Chiocchetti A, Magnani C, et al. (2005) Two single-nucleotide polymorphisms in the 5′ and 3′ ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus. Arthritis Rheum 52: 539-547.
18. Mok CC, Lau CS, Chan TM, Wong RWS (1999) Clinical characteristics and outcome of southern Chinese males with systemic lupus crythematosus. Lupus 8: 188-196.
19. Molina JF, Drenkard C, Molina J, Cardiel MH, Uribe O, et al. (1996) Systemic lupus crytematosus in males: a study of 107 Latin American patients. Medicine (Baltimore) 75: 124-130.
20. Stein CM, Olson JM, Gray-McGuire C, Bruner GR, Harley JB, et al. (2002) Increased prevalence of renal disease in systemic hipus erythematosus families with affected male relatives. Arthritis Rheum 46: 428-435.
21. Arbuckle MR, James JA, Dennis GJ, Rubertone MV, McClain MT, et al. (2003) Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus. Lupus 12: 99-106.
22. Xing C, Gray-McGuire C, Kelly JA, Carrion P, Bukulmez H, et al. (2005) Genetic linkage of systemic lupus erythematosus to 13q32 in African American families with affected male members. Hom Genet 118: 309-321.
23. Hieronymus H, Silver PA (2004) A systems view of mRNP biology. Genes Dev 18: 2845-2860.
24. Zhao J, Hyman L, Moore C (1999) Formation of mRNA 3′ ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev 63: 405-45.
25. Conne B, Stutz A, Vassalli JD (2000) The 3′ untranslated region of messenger RNA: a molecular "hotspot' for pathology? Nat Med 6: 637-641.
26. Mignone F, Gissi C, Liuni S, Pesole G (2002) Untranslated regions of mRNAs. Genome Biol 3: REVIEWS004.
27. Chabanon H, Mickelburgh I, Hesketh J (2004) Zipcodes and postage stamps: mRNA localization signals and their trans-acting binding prioteins. Brief Funct Genomic Proteomic 3: 240-256.
28. Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, et al. (2005) Systematic discovery of regulatory motifis in human promoters and 3′ UTRs by comparison of several mammals. Nature 434: 338-345.
29. Martin MM, Buckenberger JA, Jiang J, Malana GE, Nuovo GJ, et al. (2007) The human angiotensin II type I receptor +1166 A/C polymorphism attenuates microRNA-155 binding. J Biol Chem 282: 24262-24269.
30. Sun M, Hurst LD, Carmichael GG, Chen J (2005) Evidence for a preferential targeting of 3′-UTRs by cis-encoded natural antisense transcripts. Nucleci Acids Res 33: 5533-5543.
31. Zhang H, Hu J, Reece M, Tian B (2005) PolyA_DB: a database for mammalian mRNA polyadenylation. Nucleic Acids Res 33: 201-212.
32. Bao L, Zhou M, Wu L, Lu L, Godowitz D, et al. (2007) PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res 35: Database Issue D51-D54.
33. Cowley BD, Ricardo SD, Nagars S, Diamond JR (2001) Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats. Kidney International 60: 2087-2096.
34. Matkovits T, Christakos S (1995) Variable in Vivo Regulation of Rat Vitamin D-Dependent Genes Osteopontin, Ca,Mg-Adenosine Triphosphatase, and 25-Hydroxyvitamin D3 24-Hydroxylase: Implications for Differing Mechanisms of Regulation and Involvement of Multiple Factors. Endocrinology 136: 3971-3982.
35. Hochberg MC (1997) Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40: 1725.
36. Purcell S, Daly MJ, Sham PC (2007) WHAP: haplotype-based association analysis. Bioinformatics 23: 255-256.
37. Pritchard JK, Stephens M, Donnelly P (2000) Inference of population structure using multilocus genotype data. Genetics 155: 945-959.
38. Devlin B, Roeder K (1999) Genomic control for association studies. Biometrics 55: 997-1004.
39. Pritchard JK, Stephens M, Rosenberg NA, Donnelly P (2000) Association mapping in structured populations. Am J Hum Genet 67: 170-181.
40. Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38: 904-909.