High-level production of Fc-fused kringle domain in Pichia pastoris

Journal of Industrial Microbiology and Biotechnology

Volumn 41, Issue 6, 2014, Pages 989-996

  Jeong, Gu Min ^a   Lee, Yong Jae ^a   Kim, Yong Sung ^b   Jeong, Ki Jun ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Ajou University   (South Korea)

Author keywords

Fc fusion protein; Fed batch fermentation; Kringle domain; Pichia pastoris

Indexed keywords

AMMONIUM SULFATE; BIOTIN; CALCIUM CHLORIDE; GLYCEROL; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; KD548 FC FUSION PROTEIN; MAGNESIUM SULFATE; MANGANESE SULFATE; POTASSIUM DIHYDROGEN PHOSPHATE; POTASSIUM IODIDE; RECOMBINANT PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOREACTOR; CARBON SOURCE; CELL DENSITY; CELL GROWTH; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FED BATCH CULTURE; FED BATCH FERMENTATION; FUNGAL CELL; FUNGAL STRAIN; GENE EXPRESSION SYSTEM; GROWTH RATE; KRINGLE DOMAIN; LARGE SCALE PRODUCTION; NONHUMAN; PH; PICHIA PASTORIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PURIFICATION;

BIOREACTORS; CULTURE MEDIA; FERMENTATION; GLYCEROL; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN FC FRAGMENTS; KRINGLES; PICHIA; RECOMBINANT FUSION PROTEINS; TEMPERATURE;

EID: 84901337926     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-014-1435-2     Document Type: Article

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