-
1
-
-
84864274164
-
Clinical translation of folate receptor-targeted therapeutics
-
Teng L, Xie J, Teng L, Lee RJ. Clinical translation of folate receptor-targeted therapeutics. Expert Opin Drug Deliv. 2012;9:901-908.
-
(2012)
Expert Opin Drug Deliv.
, vol.9
, pp. 901-908
-
-
Teng, L.1
Xie, J.2
Teng, L.3
Lee, R.J.4
-
2
-
-
1942503303
-
Distribution, functionality and gene regulation of folate receptor isoforms: Implications in targeted therapy
-
Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Adv Drug Deliv Rev. 2004;56:1067-1084.
-
(2004)
Adv Drug Deliv Rev.
, vol.56
, pp. 1067-1084
-
-
Elnakat, H.1
Ratnam, M.2
-
3
-
-
84891854386
-
Precedent: A randomized phase ii trial comparing vintafolide (ec145) and pegylated liposomal doxorubicin (pld) in combination versus pld alone in patients with platinum-resistant ovarian cancer
-
Naumann RW, Coleman RL, Burger RA, et al. PRECEDENT: a randomized phase II trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum-resistant ovarian cancer. J Clin Oncol. 2013;31:4400-4406.
-
(2013)
J Clin Oncol.
, vol.31
, pp. 4400-4406
-
-
Naumann, R.W.1
Coleman, R.L.2
Burger, R.A.3
-
4
-
-
84901293905
-
Folate-receptor targeted radionuclide imaging agents
-
Jackman AL, Leamon CP, eds. New York, NY: Springer
-
Muller C, Schibli R. Folate-receptor targeted radionuclide imaging agents. In: Jackman AL, Leamon CP, eds. Targeted Drug Strategies for Cancer and Inflammation. New York, NY: Springer; 2011:65-92.
-
(2011)
Targeted Drug Strategies for Cancer and Inflammation.
, pp. 65-92
-
-
Muller, C.1
Schibli, R.2
-
5
-
-
39249085399
-
Folate receptor alpha as a tumor target in epithelial ovarian cancer
-
Kalli KR, Oberg AL, Keeney GL, et al. Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol. 2008;108:619-626.
-
(2008)
Gynecol Oncol.
, vol.108
, pp. 619-626
-
-
Kalli, K.R.1
Oberg, A.L.2
Keeney, G.L.3
-
6
-
-
84862808121
-
Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response
-
Chen YL, Chang MC, Huang CY, et al. Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response. Mol Oncol. 2012;6:360-369.
-
(2012)
Mol Oncol.
, vol.6
, pp. 360-369
-
-
Chen, Y.L.1
Chang, M.C.2
Huang, C.Y.3
-
7
-
-
84868697449
-
Paradoxical impact of two folate receptors, fra and rfc, in ovarian cancer: Effect on cell proliferation, invasion and clinical outcome
-
Siu MK, Kong DS, Chan HY, et al. Paradoxical impact of two folate receptors, FRa and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome. PLoS ONE. 2012;7:e47201.
-
(2012)
PLoS ONE.
, vol.7
-
-
Siu, M.K.1
Kong, D.S.2
Chan, H.Y.3
-
8
-
-
38949215454
-
Discovery and development of folic-acidbased receptor targeting for imaging and therapy of cancer and inflammatory diseases
-
Low PS, Henne WA, Doorneweerd DD. Discovery and development of folic-acidbased receptor targeting for imaging and therapy of cancer and inflammatory diseases. Acc Chem Res. 2008;41:120-129.
-
(2008)
Acc Chem Res.
, vol.41
, pp. 120-129
-
-
Low, P.S.1
Henne, W.A.2
Doorneweerd, D.D.3
-
9
-
-
84877579319
-
Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer
-
Armstrong DK, White AJ, Weil SC, Phillips M, Coleman RL. Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer. Gynecol Oncol. 2013;129:452-458.
-
(2013)
Gynecol Oncol.
, vol.129
, pp. 452-458
-
-
Armstrong, D.K.1
White, A.J.2
Weil, S.C.3
Phillips, M.4
Coleman, R.L.5
-
10
-
-
58849142161
-
A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages
-
Xia W, Hilgenbrink AR, Matteson EL, Lockwood MB, Cheng JX, Low PS. A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages. Blood. 2009;113:438-446.
-
(2009)
Blood.
, vol.113
, pp. 438-446
-
-
Xia, W.1
Hilgenbrink, A.R.2
Matteson, E.L.3
Lockwood, M.B.4
Cheng, J.X.5
Low, P.S.6
-
11
-
-
44849127008
-
Exploratory study of 99mtc-ec20 imaging for identifying patients with folate receptor-positive solid tumors
-
Fisher RE, Siegel BA, Edell SL, et al. Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors. J Nucl Med. 2008;49:899-906.
-
(2008)
J Nucl Med.
, vol.49
, pp. 899-906
-
-
Fisher, R.E.1
Siegel, B.A.2
Edell, S.L.3
-
12
-
-
84875884456
-
Cellular heterogeneity and molecular evolution in cancer
-
Almendro V, Marusyk A, Polyak K. Cellular heterogeneity and molecular evolution in cancer. Annu Rev Pathol. 2013;8:277-302.
-
(2013)
Annu Rev Pathol.
, vol.8
, pp. 277-302
-
-
Almendro, V.1
Marusyk, A.2
Polyak, K.3
-
13
-
-
84901377262
-
Phase 2 study of treatment of advanced ovarian cancer with folate-receptor-targeted therapeutic (vintafolide) and companion spect-based imaging agent (99mtc-etarfolatide)
-
In press
-
Morris RT, Joyrich RN, Naumann RW, et al. Phase 2 study of treatment of advanced ovarian cancer with folate-receptor-targeted therapeutic (vintafolide) and companion SPECT-based imaging agent (99mTc-etarfolatide). Ann Oncol. In press.
-
Ann Oncol.
-
-
Morris, R.T.1
Joyrich, R.N.2
Naumann, R.W.3
-
14
-
-
0027439199
-
Kinetics and tissue distribution of the radiolabeled chimeric monoclonal antibody mov18 igg and f(ab9)2 fragments in ovarian carcinoma patients
-
Buist MR, Kenemans P, den Hollander W, et al. Kinetics and tissue distribution of the radiolabeled chimeric monoclonal antibody MOv18 IgG and F(ab9)2 fragments in ovarian carcinoma patients. Cancer Res. 1993;53:5413-5418.
-
(1993)
Cancer Res.
, vol.53
, pp. 5413-5418
-
-
Buist, M.R.1
Kenemans, P.2
Den Hollander, W.3
-
15
-
-
0038621645
-
Evaluation of 111in-dtpa-folate as a receptor-targeted diagnostic agent for ovarian cancer: Initial clinical results
-
Siegel BA, Dehdashti F, Mutch DG, et al. Evaluation of 111In-DTPA-folate as a receptor-targeted diagnostic agent for ovarian cancer: initial clinical results. J Nucl Med. 2003;44:700-707.
-
(2003)
J Nucl Med.
, vol.44
, pp. 700-707
-
-
Siegel, B.A.1
Dehdashti, F.2
Mutch, D.G.3
-
17
-
-
0036862058
-
Synthesis and biological evaluation of ec20: A new folate-derived, 99mtc-based radiopharmaceutical
-
Leamon CP, Parker MA, Vlahov IR, et al. Synthesis and biological evaluation of EC20: a new folate-derived, 99mTc-based radiopharmaceutical. Bioconjug Chem. 2002;13:1200-1210.
-
(2002)
Bioconjug Chem.
, vol.13
, pp. 1200-1210
-
-
Leamon, C.P.1
Parker, M.A.2
Vlahov, I.R.3
-
18
-
-
2642514921
-
Preclinical evaluation of 99mtc-ec20 for imaging folate receptor-positive tumors
-
Reddy JA, Xu LC, Parker N, Vetzel M, Leamon CP. Preclinical evaluation of 99mTc-EC20 for imaging folate receptor-positive tumors. J Nucl Med. 2004;45:857-866.
-
(2004)
J Nucl Med.
, vol.45
, pp. 857-866
-
-
Reddy, J.A.1
Xu, L.C.2
Parker, N.3
Vetzel, M.4
Leamon, C.P.5
-
19
-
-
84860726550
-
Imaging sites of infection using a 99mtc-labeled folate conjugate targeted to folate receptor positive macrophages
-
HenneWA, Rothenbuhler R, Ayala-Lopez W, XiaW, Varghese B, Low PS. Imaging sites of infection using a 99mTc-labeled folate conjugate targeted to folate receptor positive macrophages. Mol Pharm. 2012;9:1435-1440.
-
(2012)
Mol Pharm.
, vol.9
, pp. 1435-1440
-
-
Henne, W.A.1
Rothenbuhler, R.2
Ayala-Lopez, W.3
Xia, W.4
Varghese, B.5
Low, P.S.6
-
20
-
-
84863451148
-
A folate receptor-A-specific ligand that targets cancer tissue and not sites of inflammation
-
Vaitilingam B, Chelvam V, Kularatne SA, Poh S, Ayala-Lopez W, Low PS. A folate receptor-a-specific ligand that targets cancer tissue and not sites of inflammation. J Nucl Med. 2012;53:1127-1134.
-
(2012)
J Nucl Med.
, vol.53
, pp. 1127-1134
-
-
Vaitilingam, B.1
Chelvam, V.2
Kularatne, S.A.3
Poh, S.4
Ayala-Lopez, W.5
Low, P.S.6
-
21
-
-
84878269164
-
Folate-based radiotracers for pet imaging: Update and perspectives
-
Müller C. Folate-based radiotracers for PET imaging: update and perspectives. Molecules. 2013;18:5005-5031.
-
(2013)
Molecules.
, vol.18
, pp. 5005-5031
-
-
Müller, C.1
-
22
-
-
33747135111
-
Synthesis and preclinical evaluation of a folic acid derivative labeled with 18f for pet imaging of folate receptor-positive tumors
-
Bettio A, Honer M, Müller C, et al. Synthesis and preclinical evaluation of a folic acid derivative labeled with 18F for PET imaging of folate receptor-positive tumors. J Nucl Med. 2006;47:1153-1160.
-
(2006)
J Nucl Med.
, vol.47
, pp. 1153-1160
-
-
Bettio, A.1
Honer, M.2
Müller, C.3
-
23
-
-
79851482576
-
A new 18flabeled folic acid derivative with improved properties for the pet imaging of folate receptor-positive tumors
-
Ross TL, Honer M, Müller C, Groehn V, Schibli R, Ametamey SM. A new 18Flabeled folic acid derivative with improved properties for the PET imaging of folate receptor-positive tumors. J Nucl Med. 2010;51:1756-1762.
-
(2010)
J Nucl Med.
, vol.51
, pp. 1756-1762
-
-
Ross, T.L.1
Honer, M.2
Müller, C.3
Groehn, V.4
Schibli, R.5
Ametamey, S.M.6
-
24
-
-
84874067227
-
Radiosynthesis and preclinical evaluation of 39-aza-29-[18f]fluorofolic acid: A novel pet radiotracer for folate receptor targeting
-
Betzel T, Müller C, Groehn V, et al. Radiosynthesis and preclinical evaluation of 39-Aza-29-[18F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting. Bioconjug Chem. 2013;24:205-214.
-
(2013)
Bioconjug Chem.
, vol.24
, pp. 205-214
-
-
Betzel, T.1
Müller, C.2
Groehn, V.3
-
25
-
-
84859990896
-
Fluoro-deoxy-glucose folate: A novel PET radiotracer with improved in vivo properties for folate receptor targeting
-
Fischer CR, Müller C, Reber J, et al. [18F]fluoro-deoxy-glucose folate: a novel PET radiotracer with improved in vivo properties for folate receptor targeting. Bioconjug Chem. 2012;23:805-813.
-
(2012)
Bioconjug Chem.
, vol.23
, pp. 805-813
-
-
Fischer, C.R.1
Müller, C.2
Reber, J.3
-
26
-
-
84860705395
-
In vivo imaging of folate receptor positive tumor xenografts using novel 68ga-nodaga-folate conjugates
-
Fani M, Tamma ML, Nicolas GP, et al. In vivo imaging of folate receptor positive tumor xenografts using novel 68Ga-NODAGA-folate conjugates. Mol Pharm. 2012;9: 1136-1145.
-
(2012)
Mol Pharm.
, vol.9
, pp. 1136-1145
-
-
Fani, M.1
Tamma, M.L.2
Nicolas, G.P.3
-
27
-
-
79551517797
-
Development of new folate-based pet radiotracers: Preclinical evaluation of 68ga-dota-folate conjugates
-
Fani M, Wang X, Nicolas G, et al. Development of new folate-based PET radiotracers: preclinical evaluation of 68Ga-DOTA-folate conjugates. Eur J Nucl Med Mol Imaging. 2011;38:108-119.
-
(2011)
Eur J Nucl Med Mol Imaging.
, vol.38
, pp. 108-119
-
-
Fani, M.1
Wang, X.2
Nicolas, G.3
-
28
-
-
84864259555
-
Folate receptor alpha expression in lung cancer: Diagnostic and prognostic significance
-
O'Shannessy DJ, Yu G, Smale R, et al. Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance. Oncotarget. 2012;3:414-425.
-
(2012)
Oncotarget.
, vol.3
, pp. 414-425
-
-
O'Shannessy, D.J.1
Yu, G.2
Smale, R.3
-
29
-
-
80053989452
-
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-A targeting: First in-human results
-
van Dam GM, Themelis G, Crane LM, et al. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-a targeting: first in-human results. Nat Med. 2011;17:1315-1319.
-
(2011)
Nat Med.
, vol.17
, pp. 1315-1319
-
-
Van Dam, G.M.1
Themelis, G.2
Crane, L.M.3
-
30
-
-
77952295715
-
Imaging of atherosclerosis in apoliprotein e knockout mice: Targeting of a folate-conjugated radiopharmaceutical to activated macrophages
-
Ayala-Ĺopez W, Xia W, Varghese B, Low PS. Imaging of atherosclerosis in apoliprotein e knockout mice: targeting of a folate-conjugated radiopharmaceutical to activated macrophages. J Nucl Med. 2010;51:768-774.
-
(2010)
J Nucl Med.
, vol.51
, pp. 768-774
-
-
Ayala-Ĺopez, W.1
Xia, W.2
Varghese, B.3
Low, P.S.4
-
31
-
-
0036068396
-
Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis
-
Turk MJ, Breur GJ, Widmer WR, et al. Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis. Arthritis Rheum. 2002;46: 1947-1955.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 1947-1955
-
-
Turk, M.J.1
Breur, G.J.2
Widmer, W.R.3
-
32
-
-
1942503257
-
Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis
-
Paulos CM, Turk MJ, Breur GJ, Low PS. Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis. Adv Drug Deliv Rev. 2004;56:1205-1217.
-
(2004)
Adv Drug Deliv Rev.
, vol.56
, pp. 1205-1217
-
-
Paulos, C.M.1
Turk, M.J.2
Breur, G.J.3
Low, P.S.4
-
33
-
-
67249164181
-
Assessment of disease activity in rheumatoid arthritis using a novel folate targeted radiopharmaceutical folatescan
-
Matteson EL, Lowe VJ, Prendergast FG, et al. Assessment of disease activity in rheumatoid arthritis using a novel folate targeted radiopharmaceutical Folatescan. Clin Exp Rheumatol. 2009;27:253-259.
-
(2009)
Clin Exp Rheumatol.
, vol.27
, pp. 253-259
-
-
Matteson, E.L.1
Lowe, V.J.2
Prendergast, F.G.3
-
34
-
-
79959858929
-
Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomographycomputed tomography
-
Piscaer TM, Müller C, Mindt TL, et al. Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomography/computed tomography. Arthritis Rheum. 2011;63:1898-1907.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 1898-1907
-
-
Piscaer, T.M.1
Müller, C.2
Mindt, T.L.3
-
35
-
-
84898020055
-
Folate receptor-targeted single-photon emission computed tomography/computed tomography to detect activated macrophages in atherosclerosis: Can it distinguish vulnerable from stable atherosclerotic plaques?
-
Winkel LC, Groen HC, van Thiel BS, et al. Folate receptor-targeted single-photon emission computed tomography/computed tomography to detect activated macrophages in atherosclerosis: can it distinguish vulnerable from stable atherosclerotic plaques? Mol Imaging. 2013;12:1-5.
-
(2013)
Mol Imaging.
, vol.12
, pp. 1-5
-
-
Winkel, L.C.1
Groen, H.C.2
Van Thiel, B.S.3
|