Ancient evolutionary origins of epigenetic regulation associated with posttraumatic stress disorder

Frontiers in Human Neuroscience

Volumn 8, Issue MAY, 2014, Pages

  Sipahi, Levent ^a   Uddin, Monica ^a   Hou, Zhou Cheng ^a,b   Aiello, Allison E ^c   Koenen, Karestan C ^d   Galea, Sandro ^d   Wildman, Derek E ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

^c IL   (United States)

^d Department of Epidemiology University of North Carolina Gillings School of Global Public Health ^*  (United States)

Author keywords

DNA methylation; Epigenetics; Mental disorders; Molecular evolution; Posttraumatic stress disorder

Indexed keywords

ARTICLE; CHIMPANZEE; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION REGULATION; HUMAN; LAST COMMON ANCESTOR; MOLECULAR EVOLUTION; NONHUMAN; ORANG UTAN; PHENOTYPIC PLASTICITY; PHYLOGENY; POSTTRAUMATIC STRESS DISORDER; PROTEIN STRUCTURE; TRANSCRIPTION FACTOR BINDING MOTIF;

EID: 84901310665     PISSN: None     EISSN: 16625161     Source Type: Journal    
DOI: 10.3389/fnhum.2014.00284     Document Type: Article

References (40)

1. American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders: Fifth Edition (DSM-5). Arlington, VA: American Psychiatric Publishing.
2. Bradshaw, G. A., Capaldo, T., Lindner, L., and Grow, G. (2008). Building an inner sanctuary: complex PTSD in chimpanzees. J. Trauma Dissociation 9, 9-34. doi: 10.1080/15299730802073619
3. Bradshaw, G. A., Schore, A. N., Brown, J. L., Poole, J. H., and Moss, C. J. (2005). Elephant breakdown. Nature 433, 807. doi: 10.1038/433807a
4. Breslau, N., Kessler, R. C., Chilcoat, H. D., Schultz, L. R., Davis, G. C., and Andreski, P. (1998). Trauma and posttraumatic stress disorder in the community: the 1996 Detroit Area Survey of Trauma. Arch. Gen. Psychiatry 55, 626-632. doi: 10.1001/archpsyc.55.7.626
5. Cartharius, K., Frech, K., Grote, K., Klocke, B., Haltmeier, M., Klingenhoff, A., et al. (2005). MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics 21, 2933-2942. doi: 10.1093/bioinformatics/bti473
6. Chugani, H. T. (1998). A critical period of brain development: studies of cerebral glucose utilization with PET. Prev. Med. 27, 184-188. doi: 10.1006/pmed.1998.0274
7. Crews, D., Gillette, R., Scarpino, S. V., Manikkam, M., Savenkova, M. I., and Skinner, M. K. (2012). Epigenetic transgenerational inheritance of altered stress responses. Proc. Natl. Acad. Sci. U.S.A. 109, 9143-9148. doi: 10.1073/pnas.1118514109
8. Curradi, M., Izzo, A., Badaracco, G., and Landsberger, N. (2002). Molecular mechanisms of gene silencing mediated by DNA methylation. Mol. Cell. Biol. 22, 3157-3173. doi: 10.1128/MCB.22.9.3157-3173.2002
9. Ferdowsian, H. R., Durham, D. L., Kimwele, C., Kranendonk, G., Otali, E., Akugizibwe, T., et al. (2011). Signs of mood and anxiety disorders in chimpanzees. PLoS ONE 6:e19855. doi: 10.1371/journal.pone.0019855
10. Goldman, D., Oroszi, G., and Ducci, F. (2005). The genetics of addictions: uncovering the genes. Nat. Rev. Genet. 6, 521-532. doi: 10.1038/nrg1635
11. Hernando-Herraez, I., Prado-Martinez, J., Garg, P., Fernandez-Callejo, M., Heyn, H., Hvilsom, C., et al. (2013). Dynamics of DNA methylation in recent human and great ape evolution. PLoS Genet. 9:e1003763. doi: 10.1371/journal.pgen.1003763
12. Horwitz, A. V, and Wakefield, J. C. (2012). All We Have to Fear: Psychiaty's Transformation of Natural Anxieties into Mental Disorders. New York, NY: Oxford University Press.
13. Huang Da, W., Sherman, B. T., and Lempicki, R. A. (2009). Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57. doi: 10.1038/nprot.2008.211
14. Iguchi-Ariga, S. M., and Schaffner, W. (1989). CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev. 3, 612-619. doi: 10.1101/gad.3.5.612
15. Irwin, M. R., and Cole, S. W. (2011). Reciprocal regulation of the neural and innate immune systems. Nat. Rev. Immunol. 11, 625-632. doi: 10.1038/nri3042
16. Jameson, N. M., Hou, Z. C., Sterner, K. N., Weckle, A., Goodman, M., Steiper, M. E., et al. (2011). Genomic data reject the hypothesis of a prosimian primate clade. J. Hum. Evol. 61, 295-305. doi: 10.1016/j.jhevol.2011.04.004
17. Jones, K. A., and Thomsen, C. (2013). The role of the innate immune system in psychiatric disorders. Mol. Cell. Neurosci. 53, 52-62. doi: 10.1016/j.mcn.2012.10.002
18. Farris, J. S. (1970). Methods for computing Wagner trees. Syst. Zool. 19, 83-92. doi: 10.2307/2412028
19. Klengel, T., Mehta, D., Anacker, C., Rex-Haffner, M., Pruessner, J. C., Pariante, C. M., et al. (2013). Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat. Neurosci. 16, 33-41. doi: 10.1038/nn.3275
20. Meaney, M. J. (2010). Epigenetics and the biological definition of gene x environment interactions. Child Dev. 81, 41-79. doi: 10.1111/j.1467-8624.2009.01381.x
21. Mehta, D., Klengel, T., Conneely, K. N., Smith, A. K., Altmann, A., Pace, T. W., et al. (2013). Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proc. Natl. Acad. Sci. U.S.A. 110, 8302-8307. doi: 10.1073/pnas.1217750110
22. Meredith, R. W., Janecka, J. E., Gatesy, J., Ryder, O. A., Fisher, C. A., Teeling, E. C., et al. (2011). Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on mammal diversification. Science 334, 521-524. doi: 10.1126/science.1211028
23. Mier, D., Kirsch, P., and Meyer-Lindenberg, A. (2010). Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Mol. Psychiatry 15, 918-927. doi: 10.1038/mp.2009.36
24. Moore, L. D., Le, T., and Fan, G. (2013). DNA methylation and its basic function. Neuropsychopharmacology 38, 23-38. doi: 10.1038/npp.2012.112
25. Nesse, R. M. (2001). The smoke detector principle. Natural selection and the regulation of defensive responses. Ann. N. Y. Acad. Sci. 935, 75-85. doi: 10.1111/j.1749-6632.2001.tb03472.x
26. Nesse, R. M. (2005). Natural Selection and the regulation of defenses: a signal detection analysis of the smoke detector principle. Evol. Hum. Behav. 26, 88-105. doi: 10.1016/j.evolhumbehav.2004.08.002
27. Paten, B., Herrero, J., Beal, K., Fitzgerald, S., and Birney, E. (2008). Enredo and Pecan: genome-wide mammalian consistency-based multiple alignment with paralogs. Genome Res. 18, 1814-1828. doi: 10.1101/gr.076554.108
28. Pitman, R. K., Rasmusson, A. M., Koenen, K. C., Shin, L. M., Orr, S. P., Gilbertson, M. W., et al. (2012). Biological studies of post-traumatic stress disorder. Nat. Rev. Neurosci. 13, 769-787. doi: 10.1038/nrn3339
29. Quandt, K., Frech, K., Karas, H., Wingender, E., and Werner, T. (1995). MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23, 4878-4884. doi: 10.1093/nar/23.23.4878
30. Rosenbloom, K. R., Dreszer, T. R., Pheasant, M., Barber, G. P., Meyer, L. R., Pohl, A., et al. (2010). ENCODE whole-genome data in the UCSC Genome Browser. Nucleic Acids Res. 38, D620-D625. doi: 10.1093/nar/gkp961
31. Segman, R. H., Shefi, N., Goltser-Dubner, T., Friedman, N., Kaminski, N., and Shalev, A. Y. (2005). Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Mol. Psychiatry 10, 500-513, 425. doi: 10.1038/sj.mp.4001636
32. Siegmund, A., and Wotjak, C. T. (2006). Toward an animal model of posttraumatic stress disorder. Ann. N. Y. Acad. Sci. 1071, 324-334. doi: 10.1196/annals.1364.025
33. Smith, A. K., Conneely, K. N., Kilaru, V., Mercer, K. B., Weiss, T. E., Bradley, B., et al. (2011). Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 156, 700-708. doi: 10.1002/ajmg.b.31212
34. Stein, M. B., Jang, K. L., Taylor, S., Vernon, P. A., and Livesley, W. J. (2002). Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study. Am. J. Psychiatry 159, 1675-1681. doi: 10.1176/appi.ajp.159.10.1675
35. Sterner, K. N., Weckle, A., Chugani, H. T., Tarca, A. L., Sherwood, C. C., Hof, P. R., et al. (2012). Dynamic gene expression in the human cerebral cortex distinguishes children from adults. PLoS ONE 7:e37714. doi: 10.1371/journal.pone.0037714
36. Uddin, M., Aiello, A. E., Wildman, D. E., Koenen, K. C., Pawelec, G., De Los Santos, R., et al. (2010). Epigenetic and immune function profiles associated with posttraumatic stress disorder. Proc. Natl. Acad. Sci. U.S.A. 107, 9470-9475. doi: 10.1073/pnas.0910794107
37. West-Eberhard, M. (2003). Developmental Plasticity and Evolution. New York, NY: Oxford University Press.
38. Wong, C. M. (2002). Post-traumatic stress disorder: advances in psychoneuroimmunology. Psychiatr. Clin. North Am. 25, 369-383, vii. doi: 10.1016/S0193-953X(01)00006-5
39. Zeng, J., Konopka, G., Hunt, B. G., Preuss, T. M., Geschwind, D., and Yi, S. V. (2012). Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution. Am. J. Hum. Genet. 91, 455-465. doi: 10.1016/j.ajhg.2012.07.024
40. Zieker, J., Zieker, D., Jatzko, A., Dietzsch, J., Nieselt, K., Schmitt, A., et al. (2007). Differential gene expression in peripheral blood of patients suffering from post-traumatic stress disorder. Mol. Psychiatry 12, 116-118. doi: 10.1038/sj.mp.4001905