T-type Ca2+ channels: New players in the aging brain

Communicative and Integrative Biology

Volumn 7, Issue 3, 2014, Pages

  Proft, Juliane ^a   Weiss, Norbert ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Alzheimer's disease; Amyloid ; Calcium channel; Calcium signaling; T type channel

Indexed keywords

EID: 84901307718     PISSN: 19420889     EISSN: 19420889     Source Type: Journal    
DOI: 10.4161/cib.28424     Document Type: Note

References (25)

1. Brini M, Calì T, Ottolini D, Carafoli E. Neuronal calcium signaling: function and dysfunction. Cell Mol Life Sci 2014; PMID:24442513; http://dx.doi. org/10.1007/s00018-013-1550-7
2. Porter NM, Thibault O, Thibault V, Chen KC, Landfield PW. Calcium channel density and hippocampal cell death with age in long-term culture. J Neurosci 1997; 17:5629-39; PMID:9204944
3. 2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. J Neurosci 2001; 21:9744-56; PMID:11739583
4. Liu J, Supnet C, Sun S, Zhang H, Good L, Popugaeva E, Bezprozvanny I. The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease. Channels (Austin) 2014; 8:8(3); PMID:24476841; http://dx.doi.org/10.4161/chan.27471
5. 2+ release. J Neurosci 2006; 26:3482-90; PMID:16571755; http://dx.doi. org/10.1523/JNEUROSCI.4171-05.2006
6. Michaelis ML, Bigelow DJ, Schöneich C, Williams TD, Ramonda L, Yin D, Hühmer AF, Yao Y, Gao J, Squier TC. Decreased plasma membrane calcium transport activity in aging brain. Life Sci 1996; 59:405-12; PMID:8761328; http://dx.doi. org/10.1016/0024-3205(96)00319-0
7. Murchison D, Griffith WH. Age-related alterations in caffeine-sensitive calcium stores and mitochondrial buffering in rat basal forebrain. Cell Calcium 1999; 25:439-52; PMID:10579055; http://dx.doi. org/10.1054/ceca.1999.0048
8. Murchison D, Zawieja DC, Griffith WH. Reduced mitochondrial buffering of voltage-gated calcium influx in aged rat basal forebrain neurons. Cell Calcium 2004; 36:61-75; PMID:15126057; http:// dx.doi.org/10.1016/j.ceca.2003.11.010
9. Tonkikh AA, Carlen PL. Impaired presynaptic cytosolic and mitochondrial calcium dynamics in aged compared to young adult hippocampal CA1 synapses ameliorated by calcium chelation. Neuroscience 2009; 159:1300-8; PMID:19215725; http://dx.doi. org/10.1016/j.neuroscience.2008.12.057
10. Tollefson GD. Short-term effects of the calcium channel blocker nimodipine (Bay-e-9736) in the management of primary degenerative dementia. Biol Psychiatry 1990; 27:1133-42; PMID:2187540; http:// dx.doi.org/10.1016/0006-3223(90)90050-C
11. Rice RA, Berchtold NC, Cotman CW, Green KN. Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production. Neurobiol Aging 2014; 35:1002-11; PMID:24268883; http://dx.doi.org/10.1016/j. neurobiolaging.2013.10.090
12. Proft J, Weiss N. A protective mutation against Alzheimer disease? Commun Integr Biol 2012; 5:301-3; PMID:23060947; http://dx.doi.org/10.4161/ cib.21799
13. Götz J, Ittner LM. Animal models of Alzheimer's disease and frontotemporal dementia. Nat Rev Neurosci 2008; 9:532-44; PMID:18568014; http://dx.doi. org/10.1038/nrn2420
14. Bell KF, Ducatenzeiler A, Ribeiro-da-Silva A, Duff K, Bennett DA, Cuello AC. The amyloid pathology progresses in a neurotransmitter-specific manner. Neurobiol Aging 2006; 27:1644-57; PMID:16271419; http://dx.doi. org/10.1016/j.neurobiolaging.2005.09.034
15. Huang L, Keyser BM, Tagmose TM, Hansen JB, Taylor JT, Zhuang H, Zhang M, Ragsdale DS, Li M. NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl) propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels. J Pharmacol Exp Ther 2004; 309:193-9; PMID:14718587; http://dx.doi. org/10.1124/jpet.103.060814
16. Leung YM, Kuo YH, Chao CC, Tsou YH, Chou CH, Lin CH, Wong KL. Osthol is a use-dependent blocker of voltage-gated Na+ channels in mouse neuroblastoma N2A cells. Planta Med 2010; 76:34-40; PMID:19639537; http://dx.doi. org/10.1055/s-0029-1185941
17. Moriguchi S, Shioda N, Yamamoto Y, Tagashira H, Fukunaga K. The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices. J Neurochem 2012; 121:44-53; PMID:22251222; http://dx.doi.org/10.1111/j.1471-4159.2012.07667.x
18. Miners JS, Jones R, Love S. Differential Changes in Aβ42 and Aβ40 with Age. J Alzheimers Dis 2014; PMID:24503618
19. Chen CC, Greene E, Bowers SR, Mellone BG. A role for the CAL1-partner Modulo in centromere integrity and accurate chromosome segregation in Drosophila. PLoS One 2012; 7:e45094; PMID:23028777; http:// dx.doi.org/10.1371/journal.pone.0045094
20. Tiraboschi P, Hansen LA, Thal LJ, Corey-Bloom J. The importance of neuritic plaques and tangles to the development and evolution of AD. Neurology 2004; 62:1984-9; PMID:15184601; http://dx.doi. org/10.1212/01.WNL.0000129697.01779.0A
21. Bouras C, Hof PR, Giannakopoulos P, Michel JP, Morrison JH. Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: a quantitative evaluation of a one-year autopsy population from a geriatric hospital. Cereb Cortex 1994; 4:138-50; PMID:8038565; http:// dx.doi.org/10.1093/cercor/4.2.138
22. Powell KL, Cain SM, Snutch TP, O'Brien TJ. Low Threshold T-type Calcium Channels as Targets for Novel Epilepsy Treatments. Br J Clin Pharmacol 2013; PMID:23834404; http://dx.doi.org/10.1111/ bcp.12205
23. Todorovic SM, Jevtovic-Todorovic V. Neuropathic pain: role for presynaptic T-type channels in nociceptive signaling. Pflugers Arch 2013; 465:921-7; PMID:23322114; http://dx.doi.org/10.1007/ s00424-012-1211-y
24. Waxman SG, Zamponi GW. Regulating excitability of peripheral afferents: emerging ion channel targets. Nat Neurosci 2014; 17:153-63; PMID:24473263; http:// dx.doi.org/10.1038/nn.3602
25. Proft J, Weiss N. Jekyll and Hide: The two faces of amyloid β. Commun Integr Biol 2012; 5:405-7; PMID:23181153; http://dx.doi.org/10.4161/ cib.22571