메뉴 건너뛰기




Volumn 5, Issue 4, 2012, Pages 301-303

A protective mutation against Alzheimer disease?

Author keywords

Secretase; Alzheimer disease; Amyloid beta (A ); Amyloid precursor protein (APP); BACE1

Indexed keywords


EID: 84869816965     PISSN: 19420889     EISSN: 19420889     Source Type: Journal    
DOI: 10.4161/cib.21799     Document Type: Article
Times cited : (5)

References (24)
  • 2
    • 29144508843 scopus 로고    scopus 로고
    • Alzheimer's Disease International. Global prevalence of dementia: a Delphi consensus study
    • Ferri CP, Prince M, Brayne C, Brodaty H, Fratiglioni L, Ganguli M, et al.; Alzheimer's Disease International. Global prevalence of dementia: a Delphi consensus study. Lancet 2005; 366:2112-7; http://dx.doi.org/10.1016/S0140-6736(05)67889-0.
    • (2005) Lancet , vol.366 , pp. 2112-2117
    • Ferri, C.P.1    Prince, M.2    Brayne, C.3    Brodaty, H.4    Fratiglioni, L.5    Ganguli, M.6
  • 3
  • 4
    • 67650844275 scopus 로고    scopus 로고
    • Kivipelto M, von Strauss E. Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
    • Qiu C, Kivipelto M, von Strauss E. Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. Dialogues Clin Neurosci 2009; 11:111-28.
    • (2009) Dialogues Clin Neurosci , vol.11 , pp. 111-128
    • Qiu, C.1
  • 6
    • 0028856460 scopus 로고
    • An English translation of Alzheimer's 1907 paper Uber eine eigenartige Erkankung der Hirnrinde
    • Alzheimer A, Stelzmann RA, Schnitzlein HN, Murtagh FR. An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde". Clin Anat 1995; 8:429-31; http://dx.doi.org/10.1002/ca.980080612.
    • (1995) Clin Anat , vol.8 , pp. 429-431
    • Alzheimer, A.1    Stelzmann, R.A.2    Schnitzlein, H.N.3    Murtagh, F.R.4
  • 7
    • 75449102536 scopus 로고    scopus 로고
    • Alzheimer's disease
    • Querfurth HW, LaFerla FM. Alzheimer's disease. N Engl J Med 2010; 362:329-44; http://dx.doi.org/10.1056/NEJMra0909142.
    • (2010) N Engl J Med; , vol.362 , pp. 329-344
    • Querfurth, H.W.1    LaFerla, F.M.2
  • 8
    • 84655166490 scopus 로고    scopus 로고
    • Identification and biology of β-secretase
    • Kandalepas PC, Vassar R. Identification and biology of β-secretase. J Neurochem 2012; 120(Suppl 1):55-61; http://dx.doi.org/10.1111/ j.1471-4159.2011.07512.x.
    • (2012) J Neurochem; , vol.120 , Issue.SUPPL 1 , pp. 55-61
    • Kandalepas, P.C.1    Vassar, R.2
  • 9
    • 0035943345 scopus 로고    scopus 로고
    • A portrait of Alzheimer secretases--new features and familiar faces
    • Esler WP, Wolfe MS. A portrait of Alzheimer secretases--new features and familiar faces. Science 2001; 293:1449-54; http://dx.doi. org/10.1126/science.1064638.
    • (2001) Science , vol.293 , pp. 1449-1454
    • Esler, W.P.1    Wolfe, M.S.2
  • 10
    • 84870001315 scopus 로고    scopus 로고
    • APP mutations table
    • Hardy J, CaC, R. APP mutations table., 2010.
    • (2010)
    • Hardy, J.1    CaC, R.2
  • 11
    • 84865176138 scopus 로고    scopus 로고
    • Locusspecific mutation databases for neurodegenerative brain diseases. Hum Mutat;
    • Cruts M, Theuns J, Van Broeckhoven C. Locusspecific mutation databases for neurodegenerative brain diseases. Hum Mutat 2012; http://dx.doi.org/10.1002/humu.22117.
    • (2012) Van Broeckhoven C
    • Cruts, M.1    Theuns, J.2
  • 13
    • 0033968306 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease
    • St George-Hyslop PH. Molecular genetics of Alzheimer's disease. Biol Psychiatry 2000; 47:183-99; http://dx.doi.org/10.1016/ S0006-3223(99)00301-7.
    • (2000) Biol Psychiatry; , vol.47 , pp. 183-199
    • St. George-Hyslop, P.H.1
  • 14
    • 84864471159 scopus 로고    scopus 로고
    • A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
    • Jonsson T, Atwal JK, Steinberg S, Snaedal J, Jonsson PV, Bjornsson S, et al. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 2012; 488:96-9; http://dx.doi.org/10.1038/nature11283.
    • (2012) Nature , vol.488 , pp. 96-99
    • Jonsson, T.1    Atwal, J.K.2    Steinberg, S.3    Snaedal, J.4    Jonsson, P.V.5    Bjornsson, S.6
  • 15
    • 62449330486 scopus 로고    scopus 로고
    • A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis
    • Di Fede G, Catania M, Morbin M, Rossi G, Suardi S, Mazzoleni G, et al. A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. Science 2009; 323:1473-7; http://dx.doi.org/10.1126/science.1168979.
    • (2009) Science , vol.323 , pp. 1473-1477
    • Di Fede, G.1    Catania, M.2    Morbin, M.3    Rossi, G.4    Suardi, S.5    Mazzoleni, G.6
  • 16
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297:353-6; http://dx.doi.org/10.1126/science. 1072994.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 17
    • 0033595706 scopus 로고    scopus 로고
    • Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 1999; 286:735-41; http://dx.doi. org/10.1126/science.286.5440.735.
    • (1999) Science , vol.286 , pp. 735-741
    • Vassar, R.1    Bennett, B.D.2    Babu-Khan, S.3    Kahn, S.4    Mendiaz, E.A.5    Denis, P.6
  • 18
    • 0033518251 scopus 로고    scopus 로고
    • Purification and cloning of amyloid precursor protein beta-secretase from human brain
    • Sinha S, Anderson JP, Barbour R, Basi GS, Caccavello R, Davis D, et al. Purification and cloning of amyloid precursor protein beta-secretase from human brain. Nature 1999; 402:537-40; http:// dx.doi.org/10.1038/990114.
    • (1999) Nature , vol.402 , pp. 537-540
    • Sinha, S.1    Anderson, J.P.2    Barbour, R.3    Basi, G.S.4    Caccavello, R.5    Davis, D.6
  • 19
    • 0033518264 scopus 로고    scopus 로고
    • Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
    • Yan R, Bienkowski MJ, Shuck ME, Miao H, Tory MC, Pauley AM, et al. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity. Nature 1999; 402:533-7; http://dx.doi.org/10.1038/990107.
    • (1999) Nature , vol.402 , pp. 533-537
    • Yan, R.1    Bienkowski, M.J.2    Shuck, M.E.3    Miao, H.4    Tory, M.C.5    Pauley, A.M.6
  • 20
    • 33750455150 scopus 로고    scopus 로고
    • Control of peripheral nerve myelination by the beta-secretase BACE1
    • Willem M, Garratt AN, Novak B, Citron M, Kaufmann S, Rittger A, et al. Control of peripheral nerve myelination by the beta-secretase BACE1. Science 2006; 314:664-6; http:// dx.doi.org/10.1126/science.1132341.
    • (2006) Science , vol.314 , pp. 664-666
    • Willem, M.1    Garratt, A.N.2    Novak, B.3    Citron, M.4    Kaufmann, S.5    Rittger, A.6
  • 21
    • 79955751702 scopus 로고    scopus 로고
    • Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system
    • Farah MH, Pan BH, Hoffman PN, Ferraris D, Tsukamoto T, Nguyen T, et al. Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system. J Neurosci 2011; 31:5744-54; http://dx.doi.org/10.1523/ JNEUROSCI.6810-10.2011.
    • (2011) J Neurosci; , vol.31 , pp. 5744-5754
    • Farah, M.H.1    Pan, B.H.2    Hoffman, P.N.3    Ferraris, D.4    Tsukamoto, T.5    Nguyen, T.6
  • 22
    • 84857736151 scopus 로고    scopus 로고
    • BACE1 dependent neuregulin processing: review [review]
    • Fleck D, Garratt AN, Haass C, Willem M. BACE1 dependent neuregulin processing: review. [review]. Curr Alzheimer Res 2012; 9:178-83; http://dx.doi. org/10.2174/156720512799361637.
    • (2012) Curr Alzheimer Res; , vol.9 , pp. 178-183
    • Fleck, D.1    Garratt, A.N.2    Haass, C.3    Willem, M.4
  • 23
    • 83055186551 scopus 로고    scopus 로고
    • Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination
    • Velanac V, Unterbarnscheidt T, Hinrichs W, Gummert MN, Fischer TM, Rossner MJ, et al. Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination. Glia 2012; 60:203-17; http://dx.doi.org/10.1002/ glia.21255.
    • (2012) Glia , vol.60 , pp. 203-217
    • Velanac, V.1    Unterbarnscheidt, T.2    Hinrichs, W.3    Gummert, M.N.4    Fischer, T.M.5    Rossner, M.J.6
  • 24
    • 84864553199 scopus 로고    scopus 로고
    • Reversal of Paralysis and Reduced Inf lammation from Peripheral Administration of beta-Amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis
    • Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, et al. Reversal of Paralysis and Reduced Inf lammation from Peripheral Administration of beta-Amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis. Sci Transl Med 2012, 4:145ra05.
    • (2012) Sci Transl Med , vol.4 , pp. 145-205
    • Grant, J.L.1    Ghosn, E.E.2    Axtell, R.C.3    Herges, K.4    Kuipers, H.F.5    Woodling, N.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.