Dimethyl fumarate inhibits the expression and function of hypoxia-inducible factor-1α (HIF-1α)

Biochemical and Biophysical Research Communications

Volumn 448, Issue 3, 2014, Pages 303-307

  Zhao, Guangzong ^a,b   Liu, Yao ^b   Fang, Jun ^b   Chen, Yunzhen ^a   Li, Huazhuang ^b   Gao, Kehai ^b  

^a SHANDONG UNIVERSITY   (China)

^b YIDU CENTRAL HOSPITAL OF WEIFANG   (China)

Author keywords

Heat shock protein 90 (Hsp90); Hypoxia; Hypoxia inducible factor 1 (HIF 1 ); Proteasomal degradation; The receptor of activated protein kinase C (RACK1)

Indexed keywords

FUMARIC ACID DIMETHYL ESTER; HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 8; PROTEASOME; RECEPTOR FOR ACTIVATED C KINASE 1; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

ANIMAL CELL; ARTICLE; CELL HYPOXIA; CELL LINE; CELL MATURATION; CONTROLLED STUDY; DRUG INHIBITION; GENE EXPRESSION; GENE TARGETING; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

HEAT SHOCK PROTEIN 90 (HSP90); HYPOXIA; HYPOXIA-INDUCIBLE FACTOR-1Α (HIF-1Α); PROTEASOMAL DEGRADATION; THE RECEPTOR OF ACTIVATED PROTEIN KINASE C (RACK1);

3T3 CELLS; ANIMALS; CELL HYPOXIA; FUMARATES; GENE EXPRESSION; HSP90 HEAT-SHOCK PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-8; MICE; NEUROPEPTIDES; OSTEOBLASTS; PROTEASOME INHIBITORS; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84901306762     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.02.062     Document Type: Article

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