NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

Nature Communications

Volumn 5, Issue , 2014, Pages

  Lu, Jiahong ^a,b   He, Liqiang ^a   Behrends, Christian ^c   Araki, Masatake ^d   Araki, Kimi ^d   Jun Wang, Qing ^e   Catanzaro, Joseph M ^f   Friedman, Scott L ^a   Zong, Wei Xing ^f   Fiel, M Isabel ^a   Li, Min ^b   Yue, Zhenyu ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^c GOETHE UNIVERSITY MEDICAL SCHOOL   (Germany)

^d KUMAMOTO UNIVERSITY   (Japan)

^e UNIVERSITY OF KENTUCKY   (United States)

^f STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 14; BECLIN 1; CELL NUCLEUS RECEPTOR; CELL PROTEIN; NUCLEAR RECEPTOR BINDING FACTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE VPS15; PROTHROMBIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; ATG14 PROTEIN, MOUSE; BECN1 PROTEIN, MOUSE; DIMETHYL SULFOXIDE; NFE2L2 PROTEIN, MOUSE; NRBF2 PROTEIN, MOUSE; PROTEIN BINDING; THAPSIGARGIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; VESICULAR TRANSPORT PROTEIN;

ALCOHOL; CELL ORGANELLE; ENZYME ACTIVITY; IDENTIFICATION METHOD; INJURY; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CELL PROTECTION; CELLULAR DISTRIBUTION; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; LIVER INJURY; LIVER NECROSIS; MICROTUBULE; MOUSE; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DRUG EFFECTS; GENE SILENCING; KNOCKOUT MOUSE; LIVER; METABOLISM; NECROSIS; PATHOLOGY; PHAGOSOME; PROTEIN DEGRADATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; CLASS III PHOSPHATIDYLINOSITOL 3-KINASES; DIMETHYL SULFOXIDE; ENDOPLASMIC RETICULUM STRESS; GENE KNOCKDOWN TECHNIQUES; LIVER; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NECROSIS; NF-E2-RELATED FACTOR 2; PHAGOSOMES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; THAPSIGARGIN; TRANSCRIPTION FACTORS; VESICULAR TRANSPORT PROTEINS;

EID: 84901304111     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4920     Document Type: Article

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