-
1
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol. 2003;21:2787-2799.
-
(2003)
J Clin Oncol.
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
2
-
-
1842471336
-
Signaling through the epidermal growth factor receptor during the development of malignancy
-
Grandis JR, Sok JC. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther. 2004;102:37-46.
-
(2004)
Pharmacol Ther.
, vol.102
, pp. 37-46
-
-
Grandis, J.R.1
Sok, J.C.2
-
3
-
-
77956268839
-
Understanding resistance to egfr inhibitorsimpact on future treatment strategies
-
Wheeler DL, Dunn EF, Harari PM. Understanding resistance to EGFR inhibitorsimpact on future treatment strategies. Nat Rev Clin Oncol. 2010;7:493-507.
-
(2010)
Nat Rev Clin Oncol.
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn, E.F.2
Harari, P.M.3
-
4
-
-
0033392005
-
Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
-
Huang SM, Harari PM. Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs. 1999;17:259-269.
-
(1999)
Invest New Drugs.
, vol.17
, pp. 259-269
-
-
Huang, S.M.1
Harari, P.M.2
-
5
-
-
0036570203
-
Zd1839 (iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase
-
Hirata A, Ogawa S, Kometani T, et al. ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res. 2002;62:2554-2560.
-
(2002)
Cancer Res.
, vol.62
, pp. 2554-2560
-
-
Hirata, A.1
Ogawa, S.2
Kometani, T.3
-
6
-
-
30344440398
-
Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation
-
Bozec A, Formento P, Ciccolini J, et al. Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation. Mol Cancer Ther. 2005;4:1962-1971.
-
(2005)
Mol Cancer Ther.
, vol.4
, pp. 1962-1971
-
-
Bozec, A.1
Formento, P.2
Ciccolini, J.3
-
7
-
-
0036782278
-
Vegf and the quest for tumour angiogenesis factors
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002;2:795-803.
-
(2002)
Nat Rev Cancer.
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
8
-
-
34147130694
-
The role of vegf and egfr inhibition: Implications for combining anti-vegf and anti-egfr agents
-
Tabernero J. The role of VEGF and EGFR inhibition: implications for combining anti-VEGF and anti-EGFR agents. Mol Cancer Res. 2007;5:203-220.
-
(2007)
Mol Cancer Res.
, vol.5
, pp. 203-220
-
-
Tabernero, J.1
-
9
-
-
85047695527
-
Constitutive stat3 activity up-regulates vegf expression and tumor angiogenesis
-
Niu G, Wright KL, Huang M, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene. 2002;21:2000-2008.
-
(2002)
Oncogene.
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
-
10
-
-
0036681995
-
Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by zd1839 (iressa)
-
Huang SM, Li J, Armstrong EA, Harari PM. Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res. 2002;62:4300-4306.
-
(2002)
Cancer Res.
, vol.62
, pp. 4300-4306
-
-
Huang, S.M.1
Li, J.2
Armstrong, E.A.3
Harari, P.M.4
-
11
-
-
33645499486
-
Egfr tyrosine kinase inhibitors decrease vegf expression by both hypoxia-inducible factor (hif)-1-independent and hif-1-dependent mechanisms
-
Pore N, Jiang Z, Gupta A, Cerniglia G, Kao GD, Maity A. EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms. Cancer Res. 2006;66:3197-3204.
-
(2006)
Cancer Res.
, vol.66
, pp. 3197-3204
-
-
Pore, N.1
Jiang, Z.2
Gupta, A.3
Cerniglia, G.4
Kao, G.D.5
Maity, A.6
-
12
-
-
0037338436
-
Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
-
Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 2003;17:545-580.
-
(2003)
Genes Dev.
, vol.17
, pp. 545-580
-
-
Massoud, T.F.1
Gambhir, S.S.2
-
13
-
-
79952071002
-
A novel mechanism of gamma/delta t-lymphocyte and endothelial activation by shear stress: The role of ecto-atp synthase beta chain
-
Fu Y, Hou Y, Fu C, et al. A novel mechanism of gamma/delta T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase beta chain. Circ Res. 2011;108:410-417.
-
(2011)
Circ Res.
, vol.108
, pp. 410-417
-
-
Fu, Y.1
Hou, Y.2
Fu, C.3
-
14
-
-
7444235966
-
In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts
-
Chen X, Conti PS, Moats RA. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res. 2004;64:8009-8014.
-
(2004)
Cancer Res.
, vol.64
, pp. 8009-8014
-
-
Chen, X.1
Conti, P.S.2
Moats, R.A.3
-
15
-
-
79551598150
-
Specific targeting of human integrin alphavbeta3 with 111in-labeled abegrin in nude mouse models
-
Liu Z, Jia B, Zhao H, Chen X, Wang F. Specific targeting of human integrin alphavbeta3 with 111In-labeled Abegrin in nude mouse models. Mol Imaging Biol. 2011;13:112-120.
-
(2011)
Mol Imaging Biol.
, vol.13
, pp. 112-120
-
-
Liu, Z.1
Jia, B.2
Zhao, H.3
Chen, X.4
Wang, F.5
-
16
-
-
34547736456
-
In vivo vegf imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft
-
Nagengast WB, de Vries EG, Hospers GA, et al. In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft. J Nucl Med. 2007;48:1313-1319.
-
(2007)
J Nucl Med.
, vol.48
, pp. 1313-1319
-
-
Nagengast, W.B.1
De Vries, E.G.2
Hospers, G.A.3
-
17
-
-
42149169958
-
Specific imaging of vegf-A expression with radiolabeled anti-vegf monoclonal antibody
-
Stollman TH, Scheer MG, Leenders WP, et al. Specific imaging of VEGF-A expression with radiolabeled anti-VEGF monoclonal antibody. Int J Cancer. 2008;122:2310-2314.
-
(2008)
Int J Cancer.
, vol.122
, pp. 2310-2314
-
-
Stollman, T.H.1
Scheer, M.G.2
Leenders, W.P.3
-
18
-
-
84875030783
-
Detection of rapalog-mediated therapeutic response in renal cancer xenografts using 64cu-bevacizumab immunopet
-
Chang AJ, Sohn R, Lu ZH, Arbeit JM, Lapi SE. Detection of rapalog-mediated therapeutic response in renal cancer xenografts using 64Cu-bevacizumab immunoPET. PLoS ONE. 2013;8:e58949.
-
(2013)
PLoS ONE.
, vol.8
-
-
Chang, A.J.1
Sohn, R.2
Lu, Z.H.3
Arbeit, J.M.4
Lapi, S.E.5
-
19
-
-
78650611346
-
Pet imaging of tumor angiogenesis in mice with vegf-A-targeted 86y-chx-a$-dtpa-bevacizumab
-
Nayak TK, Garmestani K, Baidoo KE, Milenic DE, Brechbiel MW. PET imaging of tumor angiogenesis in mice with VEGF-A-targeted 86Y-CHX-A$-DTPA- bevacizumab. Int J Cancer. 2011;128:920-926.
-
(2011)
Int J Cancer.
, vol.128
, pp. 920-926
-
-
Nayak, T.K.1
Garmestani, K.2
Baidoo, K.E.3
Milenic, D.E.4
Brechbiel, M.W.5
-
20
-
-
79958812484
-
Vegf-spect with 111in-bevacizumab in stage iii/iv melanoma patients
-
Nagengast WB, Hooge MN, van Straten EM, et al. VEGF-SPECT with 111In-bevacizumab in stage III/IV melanoma patients. Eur J Cancer. 2011;47:1595-1602.
-
(2011)
Eur J Cancer.
, vol.47
, pp. 1595-1602
-
-
Nagengast, W.B.1
Hooge, M.N.2
Van Straten, E.M.3
-
21
-
-
52649113251
-
Antibodies for molecular imaging of cancer
-
Wu AM, Olafsen T. Antibodies for molecular imaging of cancer. Cancer J. 2008;14:191-197.
-
(2008)
Cancer J.
, vol.14
, pp. 191-197
-
-
Wu, A.M.1
Olafsen, T.2
-
22
-
-
84888166523
-
Pet imaging of cd105/endoglin expression with a 61/64cu-labeled fab antibody fragment
-
Zhang Y, Hong H, Orbay H, et al. PET imaging of CD105/endoglin expression with a 61/64Cu-labeled Fab antibody fragment. Eur J Nucl Med Mol Imaging. 2013;40:759-767.
-
(2013)
Eur J Nucl Med Mol Imaging.
, vol.40
, pp. 759-767
-
-
Zhang, Y.1
Hong, H.2
Orbay, H.3
-
23
-
-
15244358941
-
Fc receptors and their role in immune regulation and autoimmunity
-
Takai T. Fc receptors and their role in immune regulation and autoimmunity. J Clin Immunol. 2005;25:1-18.
-
(2005)
J Clin Immunol.
, vol.25
, pp. 1-18
-
-
Takai, T.1
-
24
-
-
62449176798
-
On the selection of a tracer for pet imaging of her2-expressing tumors: Direct comparison of a 124i-labeled affibody molecule and trastuzumab in a murine xenograft model
-
Orlova A,Wallberg H, Stone-Elander S, Tolmachev V. On the selection of a tracer for PET imaging of HER2-expressing tumors: direct comparison of a 124I-labeled affibody molecule and trastuzumab in a murine xenograft model. J Nucl Med. 2009;50:417-425.
-
(2009)
J Nucl Med.
, vol.50
, pp. 417-425
-
-
Orlova, A.1
Wallberg, H.2
Stone-Elander, S.3
Tolmachev, V.4
-
25
-
-
66149090004
-
Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with pet
-
Dunphy MP, Lewis JS. Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with PET. J Nucl Med. 2009;50(suppl 1):106S-121S.
-
(2009)
J Nucl Med.
, vol.50
, Issue.SUPPL. 1
-
-
Dunphy, M.P.1
Lewis, J.S.2
-
26
-
-
79851504879
-
18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy
-
Sun X, Yan Y, Liu S, et al. 18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy. J Nucl Med. 2011;52:140-146.
-
(2011)
J Nucl Med.
, vol.52
, pp. 140-146
-
-
Sun, X.1
Yan, Y.2
Liu, S.3
-
27
-
-
84878663006
-
Monitoring afatinib treatment in her2-positive gastric cancer with 18f-fdg and 89zr-trastuzumab pet
-
Janjigian YY, Viola-Villegas N, Holland JP, et al. Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET. J Nucl Med. 2013;54:936-943.
-
(2013)
J Nucl Med.
, vol.54
, pp. 936-943
-
-
Janjigian, Y.Y.1
Viola-Villegas, N.2
Holland, J.P.3
-
28
-
-
33845803204
-
Antitumor activity of the epidermal growth factor receptor (egfr) tyrosine kinase inhibitor gefitinib (zd1839, iressa) in non-small cell lung cancer cell lines correlates with gene copy number and egfr mutations but not egfr protein levels
-
Helfrich BA, Raben D,Varella-Garcia M, et al. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels. Clin Cancer Res. 2006;12:7117-7125.
-
(2006)
Clin Cancer Res.
, vol.12
, pp. 7117-7125
-
-
Helfrich, B.A.1
Raben, D.2
Varella-Garcia, M.3
-
29
-
-
3843116718
-
Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('iressa', zd1839) in non-small-cell lung cancer
-
Parra HS, Cavina R, Latteri F, et al. Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('Iressa', ZD1839) in non-small-cell lung cancer. Br J Cancer. 2004;91:208-212.
-
(2004)
Br J Cancer.
, vol.91
, pp. 208-212
-
-
Parra, H.S.1
Cavina, R.2
Latteri, F.3
-
30
-
-
10344239413
-
Gefitinib: A novel targeted approach to treating cancer
-
Herbst RS, Fukuoka M, Baselga J. Gefitinib: a novel targeted approach to treating cancer. Nat Rev Cancer. 2004;4:956-965.
-
(2004)
Nat Rev Cancer.
, vol.4
, pp. 956-965
-
-
Herbst, R.S.1
Fukuoka, M.2
Baselga, J.3
-
31
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350:2129-2139.
-
(2004)
N Engl J Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
32
-
-
2342624080
-
Egfr mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304:1497-1500.
-
(2004)
Science.
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
33
-
-
27244451321
-
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
-
Takano T, Ohe Y, Sakamoto H, et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol. 2005;23:6829-6837.
-
(2005)
J Clin Oncol.
, vol.23
, pp. 6829-6837
-
-
Takano, T.1
Ohe, Y.2
Sakamoto, H.3
-
34
-
-
24644445676
-
Increased her2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients
-
Cappuzzo F, Varella-Garcia M, Shigematsu H, et al. Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients. JClin Oncol. 2005;23:5007-5018.
-
(2005)
JClin Oncol.
, vol.23
, pp. 5007-5018
-
-
Cappuzzo, F.1
Varella-Garcia, M.2
Shigematsu, H.3
-
35
-
-
4143066005
-
Direct inhibition of egf receptor activation in vascular endothelial cells by gefitinib ('iressa', zd1839)
-
Hirata A, Uehara H, Izumi K, Naito S, Kuwano M, Ono M. Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839). Cancer Sci. 2004;95:614-618.
-
(2004)
Cancer Sci.
, vol.95
, pp. 614-618
-
-
Hirata, A.1
Uehara, H.2
Izumi, K.3
Naito, S.4
Kuwano, M.5
Ono, M.6
-
36
-
-
74949130307
-
Clinical implications of nearinfrared fluorescence imaging in cancer
-
Kosaka N, Ogawa M, Choyke PL, Kobayashi H. Clinical implications of nearinfrared fluorescence imaging in cancer. Future Oncol. 2009;5:1501-1511.
-
(2009)
Future Oncol.
, vol.5
, pp. 1501-1511
-
-
Kosaka, N.1
Ogawa, M.2
Choyke, P.L.3
Kobayashi, H.4
-
37
-
-
21444441373
-
Looking and listening to light: The evolution of whole-body photonic imaging
-
Ntziachristos V, Ripoll J, Wang LV, Weissleder R. Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotechnol. 2005;23:313-320.
-
(2005)
Nat Biotechnol.
, vol.23
, pp. 313-320
-
-
Ntziachristos, V.1
Ripoll, J.2
Wang, L.V.3
Weissleder, R.4
|