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Volumn 55, Issue 5, 2014, Pages 818-823

Early assessment of tumor response to gefitinib treatment by noninvasive optical imaging of tumor vascular endothelial growth factor expression in animal models

Author keywords

Angiogenesis; EGFR; Molecular imaging; Therapy response; VEGF

Indexed keywords

BEVACIZUMAB F(AB')2 FRAGMENT; BIOLOGICAL MARKER; DYE; GEFITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84901301880     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.133660     Document Type: Article
Times cited : (20)

References (37)
  • 1
    • 0041629450 scopus 로고    scopus 로고
    • Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
    • Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol. 2003;21:2787-2799.
    • (2003) J Clin Oncol. , vol.21 , pp. 2787-2799
    • Mendelsohn, J.1    Baselga, J.2
  • 2
    • 1842471336 scopus 로고    scopus 로고
    • Signaling through the epidermal growth factor receptor during the development of malignancy
    • Grandis JR, Sok JC. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther. 2004;102:37-46.
    • (2004) Pharmacol Ther. , vol.102 , pp. 37-46
    • Grandis, J.R.1    Sok, J.C.2
  • 3
    • 77956268839 scopus 로고    scopus 로고
    • Understanding resistance to egfr inhibitorsimpact on future treatment strategies
    • Wheeler DL, Dunn EF, Harari PM. Understanding resistance to EGFR inhibitorsimpact on future treatment strategies. Nat Rev Clin Oncol. 2010;7:493-507.
    • (2010) Nat Rev Clin Oncol. , vol.7 , pp. 493-507
    • Wheeler, D.L.1    Dunn, E.F.2    Harari, P.M.3
  • 4
    • 0033392005 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
    • Huang SM, Harari PM. Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs. 1999;17:259-269.
    • (1999) Invest New Drugs. , vol.17 , pp. 259-269
    • Huang, S.M.1    Harari, P.M.2
  • 5
    • 0036570203 scopus 로고    scopus 로고
    • Zd1839 (iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase
    • Hirata A, Ogawa S, Kometani T, et al. ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res. 2002;62:2554-2560.
    • (2002) Cancer Res. , vol.62 , pp. 2554-2560
    • Hirata, A.1    Ogawa, S.2    Kometani, T.3
  • 6
    • 30344440398 scopus 로고    scopus 로고
    • Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation
    • Bozec A, Formento P, Ciccolini J, et al. Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation. Mol Cancer Ther. 2005;4:1962-1971.
    • (2005) Mol Cancer Ther. , vol.4 , pp. 1962-1971
    • Bozec, A.1    Formento, P.2    Ciccolini, J.3
  • 7
    • 0036782278 scopus 로고    scopus 로고
    • Vegf and the quest for tumour angiogenesis factors
    • Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002;2:795-803.
    • (2002) Nat Rev Cancer. , vol.2 , pp. 795-803
    • Ferrara, N.1
  • 8
    • 34147130694 scopus 로고    scopus 로고
    • The role of vegf and egfr inhibition: Implications for combining anti-vegf and anti-egfr agents
    • Tabernero J. The role of VEGF and EGFR inhibition: implications for combining anti-VEGF and anti-EGFR agents. Mol Cancer Res. 2007;5:203-220.
    • (2007) Mol Cancer Res. , vol.5 , pp. 203-220
    • Tabernero, J.1
  • 9
    • 85047695527 scopus 로고    scopus 로고
    • Constitutive stat3 activity up-regulates vegf expression and tumor angiogenesis
    • Niu G, Wright KL, Huang M, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene. 2002;21:2000-2008.
    • (2002) Oncogene. , vol.21 , pp. 2000-2008
    • Niu, G.1    Wright, K.L.2    Huang, M.3
  • 10
    • 0036681995 scopus 로고    scopus 로고
    • Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by zd1839 (iressa)
    • Huang SM, Li J, Armstrong EA, Harari PM. Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res. 2002;62:4300-4306.
    • (2002) Cancer Res. , vol.62 , pp. 4300-4306
    • Huang, S.M.1    Li, J.2    Armstrong, E.A.3    Harari, P.M.4
  • 11
    • 33645499486 scopus 로고    scopus 로고
    • Egfr tyrosine kinase inhibitors decrease vegf expression by both hypoxia-inducible factor (hif)-1-independent and hif-1-dependent mechanisms
    • Pore N, Jiang Z, Gupta A, Cerniglia G, Kao GD, Maity A. EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms. Cancer Res. 2006;66:3197-3204.
    • (2006) Cancer Res. , vol.66 , pp. 3197-3204
    • Pore, N.1    Jiang, Z.2    Gupta, A.3    Cerniglia, G.4    Kao, G.D.5    Maity, A.6
  • 12
    • 0037338436 scopus 로고    scopus 로고
    • Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
    • Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 2003;17:545-580.
    • (2003) Genes Dev. , vol.17 , pp. 545-580
    • Massoud, T.F.1    Gambhir, S.S.2
  • 13
    • 79952071002 scopus 로고    scopus 로고
    • A novel mechanism of gamma/delta t-lymphocyte and endothelial activation by shear stress: The role of ecto-atp synthase beta chain
    • Fu Y, Hou Y, Fu C, et al. A novel mechanism of gamma/delta T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase beta chain. Circ Res. 2011;108:410-417.
    • (2011) Circ Res. , vol.108 , pp. 410-417
    • Fu, Y.1    Hou, Y.2    Fu, C.3
  • 14
    • 7444235966 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts
    • Chen X, Conti PS, Moats RA. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res. 2004;64:8009-8014.
    • (2004) Cancer Res. , vol.64 , pp. 8009-8014
    • Chen, X.1    Conti, P.S.2    Moats, R.A.3
  • 15
    • 79551598150 scopus 로고    scopus 로고
    • Specific targeting of human integrin alphavbeta3 with 111in-labeled abegrin in nude mouse models
    • Liu Z, Jia B, Zhao H, Chen X, Wang F. Specific targeting of human integrin alphavbeta3 with 111In-labeled Abegrin in nude mouse models. Mol Imaging Biol. 2011;13:112-120.
    • (2011) Mol Imaging Biol. , vol.13 , pp. 112-120
    • Liu, Z.1    Jia, B.2    Zhao, H.3    Chen, X.4    Wang, F.5
  • 16
    • 34547736456 scopus 로고    scopus 로고
    • In vivo vegf imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft
    • Nagengast WB, de Vries EG, Hospers GA, et al. In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft. J Nucl Med. 2007;48:1313-1319.
    • (2007) J Nucl Med. , vol.48 , pp. 1313-1319
    • Nagengast, W.B.1    De Vries, E.G.2    Hospers, G.A.3
  • 17
    • 42149169958 scopus 로고    scopus 로고
    • Specific imaging of vegf-A expression with radiolabeled anti-vegf monoclonal antibody
    • Stollman TH, Scheer MG, Leenders WP, et al. Specific imaging of VEGF-A expression with radiolabeled anti-VEGF monoclonal antibody. Int J Cancer. 2008;122:2310-2314.
    • (2008) Int J Cancer. , vol.122 , pp. 2310-2314
    • Stollman, T.H.1    Scheer, M.G.2    Leenders, W.P.3
  • 18
    • 84875030783 scopus 로고    scopus 로고
    • Detection of rapalog-mediated therapeutic response in renal cancer xenografts using 64cu-bevacizumab immunopet
    • Chang AJ, Sohn R, Lu ZH, Arbeit JM, Lapi SE. Detection of rapalog-mediated therapeutic response in renal cancer xenografts using 64Cu-bevacizumab immunoPET. PLoS ONE. 2013;8:e58949.
    • (2013) PLoS ONE. , vol.8
    • Chang, A.J.1    Sohn, R.2    Lu, Z.H.3    Arbeit, J.M.4    Lapi, S.E.5
  • 19
    • 78650611346 scopus 로고    scopus 로고
    • Pet imaging of tumor angiogenesis in mice with vegf-A-targeted 86y-chx-a$-dtpa-bevacizumab
    • Nayak TK, Garmestani K, Baidoo KE, Milenic DE, Brechbiel MW. PET imaging of tumor angiogenesis in mice with VEGF-A-targeted 86Y-CHX-A$-DTPA- bevacizumab. Int J Cancer. 2011;128:920-926.
    • (2011) Int J Cancer. , vol.128 , pp. 920-926
    • Nayak, T.K.1    Garmestani, K.2    Baidoo, K.E.3    Milenic, D.E.4    Brechbiel, M.W.5
  • 20
    • 79958812484 scopus 로고    scopus 로고
    • Vegf-spect with 111in-bevacizumab in stage iii/iv melanoma patients
    • Nagengast WB, Hooge MN, van Straten EM, et al. VEGF-SPECT with 111In-bevacizumab in stage III/IV melanoma patients. Eur J Cancer. 2011;47:1595-1602.
    • (2011) Eur J Cancer. , vol.47 , pp. 1595-1602
    • Nagengast, W.B.1    Hooge, M.N.2    Van Straten, E.M.3
  • 21
    • 52649113251 scopus 로고    scopus 로고
    • Antibodies for molecular imaging of cancer
    • Wu AM, Olafsen T. Antibodies for molecular imaging of cancer. Cancer J. 2008;14:191-197.
    • (2008) Cancer J. , vol.14 , pp. 191-197
    • Wu, A.M.1    Olafsen, T.2
  • 22
    • 84888166523 scopus 로고    scopus 로고
    • Pet imaging of cd105/endoglin expression with a 61/64cu-labeled fab antibody fragment
    • Zhang Y, Hong H, Orbay H, et al. PET imaging of CD105/endoglin expression with a 61/64Cu-labeled Fab antibody fragment. Eur J Nucl Med Mol Imaging. 2013;40:759-767.
    • (2013) Eur J Nucl Med Mol Imaging. , vol.40 , pp. 759-767
    • Zhang, Y.1    Hong, H.2    Orbay, H.3
  • 23
    • 15244358941 scopus 로고    scopus 로고
    • Fc receptors and their role in immune regulation and autoimmunity
    • Takai T. Fc receptors and their role in immune regulation and autoimmunity. J Clin Immunol. 2005;25:1-18.
    • (2005) J Clin Immunol. , vol.25 , pp. 1-18
    • Takai, T.1
  • 24
    • 62449176798 scopus 로고    scopus 로고
    • On the selection of a tracer for pet imaging of her2-expressing tumors: Direct comparison of a 124i-labeled affibody molecule and trastuzumab in a murine xenograft model
    • Orlova A,Wallberg H, Stone-Elander S, Tolmachev V. On the selection of a tracer for PET imaging of HER2-expressing tumors: direct comparison of a 124I-labeled affibody molecule and trastuzumab in a murine xenograft model. J Nucl Med. 2009;50:417-425.
    • (2009) J Nucl Med. , vol.50 , pp. 417-425
    • Orlova, A.1    Wallberg, H.2    Stone-Elander, S.3    Tolmachev, V.4
  • 25
    • 66149090004 scopus 로고    scopus 로고
    • Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with pet
    • Dunphy MP, Lewis JS. Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with PET. J Nucl Med. 2009;50(suppl 1):106S-121S.
    • (2009) J Nucl Med. , vol.50 , Issue.SUPPL. 1
    • Dunphy, M.P.1    Lewis, J.S.2
  • 26
    • 79851504879 scopus 로고    scopus 로고
    • 18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy
    • Sun X, Yan Y, Liu S, et al. 18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy. J Nucl Med. 2011;52:140-146.
    • (2011) J Nucl Med. , vol.52 , pp. 140-146
    • Sun, X.1    Yan, Y.2    Liu, S.3
  • 27
    • 84878663006 scopus 로고    scopus 로고
    • Monitoring afatinib treatment in her2-positive gastric cancer with 18f-fdg and 89zr-trastuzumab pet
    • Janjigian YY, Viola-Villegas N, Holland JP, et al. Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET. J Nucl Med. 2013;54:936-943.
    • (2013) J Nucl Med. , vol.54 , pp. 936-943
    • Janjigian, Y.Y.1    Viola-Villegas, N.2    Holland, J.P.3
  • 28
    • 33845803204 scopus 로고    scopus 로고
    • Antitumor activity of the epidermal growth factor receptor (egfr) tyrosine kinase inhibitor gefitinib (zd1839, iressa) in non-small cell lung cancer cell lines correlates with gene copy number and egfr mutations but not egfr protein levels
    • Helfrich BA, Raben D,Varella-Garcia M, et al. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels. Clin Cancer Res. 2006;12:7117-7125.
    • (2006) Clin Cancer Res. , vol.12 , pp. 7117-7125
    • Helfrich, B.A.1    Raben, D.2    Varella-Garcia, M.3
  • 29
    • 3843116718 scopus 로고    scopus 로고
    • Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('iressa', zd1839) in non-small-cell lung cancer
    • Parra HS, Cavina R, Latteri F, et al. Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('Iressa', ZD1839) in non-small-cell lung cancer. Br J Cancer. 2004;91:208-212.
    • (2004) Br J Cancer. , vol.91 , pp. 208-212
    • Parra, H.S.1    Cavina, R.2    Latteri, F.3
  • 30
    • 10344239413 scopus 로고    scopus 로고
    • Gefitinib: A novel targeted approach to treating cancer
    • Herbst RS, Fukuoka M, Baselga J. Gefitinib: a novel targeted approach to treating cancer. Nat Rev Cancer. 2004;4:956-965.
    • (2004) Nat Rev Cancer. , vol.4 , pp. 956-965
    • Herbst, R.S.1    Fukuoka, M.2    Baselga, J.3
  • 31
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350:2129-2139.
    • (2004) N Engl J Med. , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 32
    • 2342624080 scopus 로고    scopus 로고
    • Egfr mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304:1497-1500.
    • (2004) Science. , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 33
    • 27244451321 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
    • Takano T, Ohe Y, Sakamoto H, et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol. 2005;23:6829-6837.
    • (2005) J Clin Oncol. , vol.23 , pp. 6829-6837
    • Takano, T.1    Ohe, Y.2    Sakamoto, H.3
  • 34
    • 24644445676 scopus 로고    scopus 로고
    • Increased her2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients
    • Cappuzzo F, Varella-Garcia M, Shigematsu H, et al. Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients. JClin Oncol. 2005;23:5007-5018.
    • (2005) JClin Oncol. , vol.23 , pp. 5007-5018
    • Cappuzzo, F.1    Varella-Garcia, M.2    Shigematsu, H.3
  • 35
    • 4143066005 scopus 로고    scopus 로고
    • Direct inhibition of egf receptor activation in vascular endothelial cells by gefitinib ('iressa', zd1839)
    • Hirata A, Uehara H, Izumi K, Naito S, Kuwano M, Ono M. Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839). Cancer Sci. 2004;95:614-618.
    • (2004) Cancer Sci. , vol.95 , pp. 614-618
    • Hirata, A.1    Uehara, H.2    Izumi, K.3    Naito, S.4    Kuwano, M.5    Ono, M.6
  • 36
    • 74949130307 scopus 로고    scopus 로고
    • Clinical implications of nearinfrared fluorescence imaging in cancer
    • Kosaka N, Ogawa M, Choyke PL, Kobayashi H. Clinical implications of nearinfrared fluorescence imaging in cancer. Future Oncol. 2009;5:1501-1511.
    • (2009) Future Oncol. , vol.5 , pp. 1501-1511
    • Kosaka, N.1    Ogawa, M.2    Choyke, P.L.3    Kobayashi, H.4
  • 37
    • 21444441373 scopus 로고    scopus 로고
    • Looking and listening to light: The evolution of whole-body photonic imaging
    • Ntziachristos V, Ripoll J, Wang LV, Weissleder R. Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotechnol. 2005;23:313-320.
    • (2005) Nat Biotechnol. , vol.23 , pp. 313-320
    • Ntziachristos, V.1    Ripoll, J.2    Wang, L.V.3    Weissleder, R.4


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