The Mechanism of allosteric inhibition of protein tyrosine phosphatase 1B

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Li, Shuai ^a   Zhang, Jingmiao ^a   Lu, Shaoyong ^a   Huang, Wenkang ^a   Geng, Lv ^a   Shen, Qiancheng ^a   Zhang, Jian ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE 1B; SERINE; TYROSINE; BENZOFURAN; BENZOFURAN DERIVATIVE; PROTEIN BINDING; PTPN1 PROTEIN, HUMAN;

ALLOSTERISM; ALPHA HELIX; ARTICLE; CHEMICAL PHENOMENA; CONFORMATION; CONTROLLED STUDY; ENZYME INHIBITION; HYDROGEN BOND; MOLECULAR DYNAMICS; PRINCIPAL COMPONENT ANALYSIS; PROTEIN INTERACTION; SIMULATION; BINDING SITE; CHEMISTRY; DRUG DESIGN; ENZYME ACTIVE SITE; MUTATION; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; BENZOFURANS; CATALYTIC DOMAIN; DRUG DESIGN; MOLECULAR DYNAMICS SIMULATION; MUTATION; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; SIGNAL TRANSDUCTION;

EID: 84901295344     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097668     Document Type: Article

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