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Volumn 9, Issue 1, 2014, Pages 129-134

Research progress on the mechanisms of combined bevacizumab and radiotherapy

Author keywords

Angiogenesis; Anti angiogenic therapies; Bevacizumab; Radiosensitivity; Radiotherapy

Indexed keywords

BEVACIZUMAB; FIBROBLAST GROWTH FACTOR 2; VASCULOTROPIN;

EID: 84901284994     PISSN: 15748928     EISSN: 22123970     Source Type: Journal    
DOI: 10.2174/15748928113089990044     Document Type: Article
Times cited : (16)

References (78)
  • 1
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003; 9(6): 669-76.
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 2
    • 1842415455 scopus 로고    scopus 로고
    • Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer
    • Takahashi Y, Tucker SL, Kitadai Y, Koura AN, Bucana CD, Cleary KR, et al. Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer. Arch Surg 1997; 1325: 541-6.
    • (1997) Arch Surg , vol.1325 , pp. 541-546
    • Takahashi, Y.1    Tucker, S.L.2    Kitadai, Y.3    Koura, A.N.4    Bucana, C.D.5    Cleary, K.R.6
  • 3
    • 0031032073 scopus 로고    scopus 로고
    • Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma
    • Gasparini G, Toi M, Gion M, Verderio P, Dittadi R, Hanatani M, et al. Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J Natl Cancer Inst 1997; 89(2): 139-47.
    • (1997) J Natl Cancer Inst , vol.89 , Issue.2 , pp. 139-147
    • Gasparini, G.1    Toi, M.2    Gion, M.3    Verderio, P.4    Dittadi, R.5    Hanatani, M.6
  • 4
    • 84876119598 scopus 로고    scopus 로고
    • Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resection
    • Friedman GK, Spiller SE, Harrison DK, Fiveash JB, Reddy AT. Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resection. J Pediatr Hematol Oncol 2013; 35(3): 123-6.
    • (2013) J Pediatr Hematol Oncol , vol.35 , Issue.3 , pp. 123-126
    • Friedman, G.K.1    Spiller, S.E.2    Harrison, D.K.3    Fiveash, J.B.4    Reddy, A.T.5
  • 7
    • 70249130566 scopus 로고    scopus 로고
    • Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation therapy oncology group RTOG 0411
    • Crane CH, Winter K, Regine WF, Safran H, Rich TA, Curran W, et al. Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation therapy oncology group RTOG 0411. J Clin Oncol 2009; 27(25): 4096-102.
    • (2009) J Clin Oncol , vol.27 , Issue.25 , pp. 4096-4102
    • Crane, C.H.1    Winter, K.2    Regine, W.F.3    Safran, H.4    Rich, T.A.5    Curran, W.6
  • 8
    • 45249097586 scopus 로고    scopus 로고
    • Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up front treatment of patients with newly diagnosed glioblastoma multiforme: Interim analysis of safety and tolerability
    • Lai A, Filka E, McGibbon B, Nghiemphu PL, Graham C, Yong WH, et al. Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up front treatment of patients with newly diagnosed glioblastoma multiforme: Interim analysis of safety and tolerability. Int J Radiat Oncol Biol Phys 2008; 71(5): 1372-1380.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , Issue.5 , pp. 1372-1380
    • Lai, A.1    Filka, E.2    McGibbon, B.3    Nghiemphu, P.L.4    Graham, C.5    Yong, W.H.6
  • 9
    • 76049088643 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer
    • Crane CH, Eng C, Feig BW, Das P, Skibber JM, Chang GJ, et al. Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 2010; 76(3): 824-30.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , Issue.3 , pp. 824-830
    • Crane, C.H.1    Eng, C.2    Feig, B.W.3    Das, P.4    Skibber, J.M.5    Chang, G.J.6
  • 12
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
    • Gerber HP, Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 2005; 65(3): 671-80.
    • (2005) Cancer Res , vol.65 , Issue.3 , pp. 671-680
    • Gerber, H.P.1    Ferrara, N.2
  • 15
    • 22244452376 scopus 로고    scopus 로고
    • VEGF-targeted therapy: Therapeutic potential and recent advances
    • Rosen LS. VEGF-targeted therapy: Therapeutic potential and recent advances. Oncologist 2005; 10(6): 382-91.
    • (2005) Oncologist , vol.10 , Issue.6 , pp. 382-391
    • Rosen, L.S.1
  • 16
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005; 23(5): 1011-27.
    • (2005) J Clin Oncol , vol.23 , Issue.5 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 19
    • 0036240885 scopus 로고    scopus 로고
    • Clinical experience with angiogenesis signaling inhibitors: Focus on vascular endothelial growth factor (VEGF) blockers
    • Rosen LS. Clinical experience with angiogenesis signaling inhibitors: Focus on vascular endothelial growth factor (VEGF) blockers. Cancer Control 2002; 9(s2): 36-44.
    • (2002) Cancer Control , vol.9 , Issue.s2 , pp. 36-44
    • Rosen, L.S.1
  • 20
    • 20044375603 scopus 로고    scopus 로고
    • Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro
    • Wang Y, Fei D, Vanderlaan M, Song A. Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro. Angiogenesis 2004; 7(4): 335-45.
    • (2004) Angiogenesis , vol.7 , Issue.4 , pp. 335-345
    • Wang, Y.1    Fei, D.2    Vanderlaan, M.3    Song, A.4
  • 21
    • 67649413175 scopus 로고    scopus 로고
    • Process in the mechanisms of endostatin combined with radiotherapy
    • Zhuang HQ, Yuan ZY. Process in the mechanisms of endostatin combined with radiotherapy. Cancer Lett 2009(1); 282: 9-13.
    • (2009) Cancer Lett , vol.282 , Issue.1 , pp. 9-13
    • Zhuang, H.Q.1    Yuan, Z.Y.2
  • 22
    • 35748970483 scopus 로고    scopus 로고
    • Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
    • Fukumura D, Jain RK. Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization. Microvasc Res 2007; 74(2-3): 72-84.
    • (2007) Microvasc Res , vol.74 , Issue.2-3 , pp. 72-84
    • Fukumura, D.1    Jain, R.K.2
  • 23
    • 77950279550 scopus 로고    scopus 로고
    • Tumor microvasculature and microenvironment: Novel insights through intravital imaging in pre clinical models
    • Fukumura D, Duda DG, Munn LL, Jain RK. Tumor microvasculature and microenvironment: Novel insights through intravital imaging in pre clinical models. Microcirculation 2010; 17(3): 206-25.
    • (2010) Microcirculation , vol.17 , Issue.3 , pp. 206-225
    • Fukumura, D.1    Duda, D.G.2    Munn, L.L.3    Jain, R.K.4
  • 24
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy. Science 2005; 307: 58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 25
    • 34548267693 scopus 로고    scopus 로고
    • Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: A potential strategy for plaque stabilization
    • Jain RK, Finn AV, Kolodgie FD, Gold HK, Virmani R. Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: A potential strategy for plaque stabilization. Nat Clin Pract Cardiovasc Med 2007; 4(5706): 491-502.
    • (2007) Nat Clin Pract Cardiovasc Med , vol.4 , Issue.5706 , pp. 491-502
    • Jain, R.K.1    Finn, A.V.2    Kolodgie, F.D.3    Gold, H.K.4    Virmani, R.5
  • 26
    • 0038235987 scopus 로고    scopus 로고
    • Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11
    • Wildiers H, Guetens G, De BG, Verbeken E, Landuyt B, Landuyt W, et al. Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11. Br J Cancer 2003; 88(12): 1979-86.
    • (2003) Br J Cancer , vol.88 , Issue.12 , pp. 1979-1986
    • Wildiers, H.1    Guetens, G.2    De, B.G.3    Verbeken, E.4    Landuyt, B.5    Landuyt, W.6
  • 27
    • 36948998969 scopus 로고    scopus 로고
    • Antiangiogenic therapy in malignant glioma: Promise and challenge
    • Sathornsumetee S, Rich JN. Antiangiogenic therapy in malignant glioma: Promise and challenge. Curr Pharm Des 2007; 13(35): 3545-58.
    • (2007) Curr Pharm Des , vol.13 , Issue.35 , pp. 3545-3558
    • Sathornsumetee, S.1    Rich, J.N.2
  • 28
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407(6801): 249-57.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 29
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6: 389-95.
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 30
    • 0033793881 scopus 로고    scopus 로고
    • VEGF gene therapy: Stimulating angiogenesis or angioma-genesis
    • Carmeliet P. VEGF gene therapy: Stimulating angiogenesis or angioma-genesis. Nat Med 2000; 6: 1102-103.
    • (2000) Nat Med , vol.6 , pp. 1102-1103
    • Carmeliet, P.1
  • 31
    • 5044238876 scopus 로고    scopus 로고
    • Integrin signalling during tumour progression
    • Guo W, Giancotti FG. Integrin signalling during tumour progression. Nat Rev Mol Cell Biol 2004; 5(10): 816-26.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , Issue.10 , pp. 816-826
    • Guo, W.1    Giancotti, F.G.2
  • 32
    • 0037154738 scopus 로고    scopus 로고
    • Effect of p53 status on tumor response to antiangiogenic therapy
    • Yu JL, Rak JW, Coomber BL, Hicklin DJ, Kerbel RS. Effect of p53 status on tumor response to antiangiogenic therapy. Science 2002; 295(5559): 1526-8.
    • (2002) Science , vol.295 , Issue.5559 , pp. 1526-1528
    • Yu, J.L.1    Rak, J.W.2    Coomber, B.L.3    Hicklin, D.J.4    Kerbel, R.S.5
  • 33
    • 33744466541 scopus 로고    scopus 로고
    • Antiangiogenic therapy: A universal chemosensitization strategy for cancer
    • Kerbel RS. Antiangiogenic therapy: A universal chemosensitization strategy for cancer Science 2006; 312 (5777): 1171-5.
    • (2006) Science , vol.312 , Issue.5777 , pp. 1171-1175
    • Kerbel, R.S.1
  • 34
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion Cell 2005; 121(3): 335-48.
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6
  • 35
    • 33845767868 scopus 로고    scopus 로고
    • Macrophages regulate the angiogenic switch in a mouse model of breast cancer
    • Lin EY, Li JF, Gnatovskiy L, Yan D, Liyin Z, Dustin AG. et al. Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res 2006; 66(23): 11238-46
    • (2006) Cancer Res , vol.66 , Issue.23 , pp. 11238-11246
    • Lin, E.Y.1    Li, J.F.2    Gnatovskiy, L.3    Yan, D.4    Liyin, Z.5    Dustin, A.G.6
  • 36
    • 8544249895 scopus 로고    scopus 로고
    • Tumor-associated endothelial cells with cytogenetic abnormalities
    • Hida K, Hida Y, Amin DN, Flint AF, Panigrahy D, Morton CC, et al. Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res 2004; 64(22): 8249-55.
    • (2004) Cancer Res , vol.64 , Issue.22 , pp. 8249-8255
    • Hida, K.1    Hida, Y.2    Amin, D.N.3    Flint, A.F.4    Panigrahy, D.5    Morton, C.C.6
  • 37
    • 67650689632 scopus 로고    scopus 로고
    • Radiosensitizing effects of gefitinib at different administration times in vitro
    • Zhuang HQ, Sun J, Yuan ZY, Wang J, Zhao LJ, Wang P, et al. Radiosensitizing effects of gefitinib at different administration times in vitro. Cancer Sci 2009; 100(8): 1520-5.
    • (2009) Cancer Sci , vol.100 , Issue.8 , pp. 1520-1525
    • Zhuang, H.Q.1    Sun, J.2    Yuan, Z.Y.3    Wang, J.4    Zhao, L.J.5    Wang, P.6
  • 38
    • 0027931008 scopus 로고
    • Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
    • McIlwrath AJ, Vasey PA, Ross GM, Brown R. Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity. Cancer Res 1994; 54(14): 3718-22.
    • (1994) Cancer Res , vol.54 , Issue.14 , pp. 3718-3722
    • McIlwrath, A.J.1    Vasey, P.A.2    Ross, G.M.3    Brown, R.4
  • 39
    • 21744437791 scopus 로고    scopus 로고
    • Repopulation of cancer cells during therapy: An important cause of treatment failure
    • Kim JJ, Tannock IF. Repopulation of cancer cells during therapy: An important cause of treatment failure. Nat Rev Cancer 2005; 5(7): 516-25.
    • (2005) Nat Rev Cancer , vol.5 , Issue.7 , pp. 516-525
    • Kim, J.J.1    Tannock, I.F.2
  • 40
    • 0041672482 scopus 로고    scopus 로고
    • SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
    • Schueneman AJ, Himmelfarb E, Geng L, Tan J, Donnelly E, Mendel D, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 2003; 63(14): 4009-16.
    • (2003) Cancer Res , vol.63 , Issue.14 , pp. 4009-4016
    • Schueneman, A.J.1    Himmelfarb, E.2    Geng, L.3    Tan, J.4    Donnelly, E.5    Mendel, D.6
  • 41
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. Faseb J 1999; 13(1): 9-22.
    • (1999) Faseb J , vol.13 , Issue.1 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 42
    • 7444245046 scopus 로고    scopus 로고
    • Triple combination of irradiation, chemotherapy (pemetrexed), and VEGFR inhibition (SU5416) in human endothelial and tumor cells
    • Bischof M, Abdollahi A, Gong P, Stoffregen C, Lipson KE, Debus JU, et al. Triple combination of irradiation, chemotherapy (pemetrexed), and VEGFR inhibition (SU5416) in human endothelial and tumor cells. Int J Radiat Oncol Biol Phys 2004; 60(4): 1220-32.
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , Issue.4 , pp. 1220-1232
    • Bischof, M.1    Abdollahi, A.2    Gong, P.3    Stoffregen, C.4    Lipson, K.E.5    Debus, J.U.6
  • 43
    • 0038756364 scopus 로고    scopus 로고
    • SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro
    • Abdollahi A, Lipson KE, Han X, Krempien R, Trinh T, Weber KJ, et al. SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro. Cancer Res 2003; 63(13): 3755-63.
    • (2003) Cancer Res , vol.63 , Issue.13 , pp. 3755-3763
    • Abdollahi, A.1    Lipson, K.E.2    Han, X.3    Krempien, R.4    Trinh, T.5    Weber, K.J.6
  • 44
    • 19944422751 scopus 로고    scopus 로고
    • Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
    • Winkler F, Kozin SV, Tong RT, Chae SS, Booth MF, Garkavtsev I, et al. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004; 6(6): 553-63.
    • (2004) Cancer Cell , vol.6 , Issue.6 , pp. 553-563
    • Winkler, F.1    Kozin, S.V.2    Tong, R.T.3    Chae, S.S.4    Booth, M.F.5    Garkavtsev, I.6
  • 45
    • 2542628099 scopus 로고    scopus 로고
    • Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
    • Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, Jain RK. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res 2004; 64(11): 3731-6.
    • (2004) Cancer Res , vol.64 , Issue.11 , pp. 3731-3736
    • Tong, R.T.1    Boucher, Y.2    Kozin, S.V.3    Winkler, F.4    Hicklin, D.J.5    Jain, R.K.6
  • 46
    • 34548267693 scopus 로고    scopus 로고
    • Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: A potential strategy for plaque stabilization
    • Jain RK, Finn AV, Kolodgie FD, Gold HK, Virmani R. Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: A potential strategy for plaque stabilization. Nat Clin Pract Cardiovasc Med 2007; 4(9): 491-502.
    • (2007) Nat Clin Pract Cardiovasc Med , vol.4 , Issue.9 , pp. 491-502
    • Jain, R.K.1    Finn, A.V.2    Kolodgie, F.D.3    Gold, H.K.4    Virmani, R.5
  • 47
    • 67650648497 scopus 로고    scopus 로고
    • Endostar, a recombined humanized endostatin, enhances the radioresponse for human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts in mice
    • Wen QL, Meng MB, Yang B, Tu LL, Jia L, Zhou L, et al. Endostar, a recombined humanized endostatin, enhances the radioresponse for human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts in mice. Cancer Sci 2009; 100(8): 1510-9.
    • (2009) Cancer Sci , vol.100 , Issue.8 , pp. 1510-1519
    • Wen, Q.L.1    Meng, M.B.2    Yang, B.3    Tu, L.L.4    Jia, L.5    Zhou, L.6
  • 48
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy. Science 2005;307(5706): 58-62.
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 49
    • 35748970483 scopus 로고    scopus 로고
    • Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
    • Fukumura D, Jain RK. Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization. Microvasc Res 2007; 74(2-3): 72-84.
    • (2007) Microvasc Res , vol.74 , Issue.2-3 , pp. 72-84
    • Fukumura, D.1    Jain, R.K.2
  • 50
    • 2942558419 scopus 로고    scopus 로고
    • Maximizing the potential of bevacizumab in cancer treatment
    • Bergsland E, Dickler MN. Maximizing the potential of bevacizumab in cancer treatment. Oncologist 2004;9 Suppl1: 36-42.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 1 , pp. 36-42
    • Bergsland, E.1    Dickler, M.N.2
  • 51
    • 5044223266 scopus 로고    scopus 로고
    • Improving tumor response to radiotherapy by targeting angiogenesis signaling pathways
    • Wachsberger P, Burd R, Dicker AP. Improving tumor response to radiotherapy by targeting angiogenesis signaling pathways. Hematol Oncol Clin North Am 2004; 18 (5):1039-57.
    • (2004) Hematol Oncol Clin North Am , vol.18 , Issue.5 , pp. 1039-1057
    • Wachsberger, P.1    Burd, R.2    Dicker, A.P.3
  • 52
    • 0038176480 scopus 로고    scopus 로고
    • Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: Exploring mechanisms of interaction
    • Wachsberger P, Burd R, Dicker AP. Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: Exploring mechanisms of interaction. Clin Cancer Res 2003; 9(6): 1957-71.
    • (2003) Clin Cancer Res , vol.9 , Issue.6 , pp. 1957-1971
    • Wachsberger, P.1    Burd, R.2    Dicker, A.P.3
  • 53
    • 33750360895 scopus 로고    scopus 로고
    • Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: Theory and clinical practice
    • Willett CG, Kozin SV, Duda DG, Di TE, Kozak KR, Boucher Y, et al. Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: Theory and clinical practice. Semin Oncol 2006; 33(5 Suppl 10): S35-40.
    • (2006) Semin Oncol , vol.33 , Issue.5 SUPPL. 10
    • Willett, C.G.1    Kozin, S.V.2    Duda, D.G.3    Di, T.E.4    Kozak, K.R.5    Boucher, Y.6
  • 54
    • 8844235660 scopus 로고    scopus 로고
    • Angiogenesis imaging ultrasound
    • Cosgrove D. Angiogenesis imaging ultrasound. Br J Radiol 2003; 76(1): S43-49.
    • (2003) Br J Radiol , vol.76 , Issue.1
    • Cosgrove, D.1
  • 55
    • 31344457770 scopus 로고    scopus 로고
    • Angiogenesis imaging in the management of prostate cancer
    • Padhani AR, Harvey CJ, Cosgrove DO. Angiogenesis imaging in the management of prostate cancer. Nat Clin Pract Urol 2005; 2(12): 596-607.
    • (2005) Nat Clin Pract Urol , vol.2 , Issue.12 , pp. 596-607
    • Padhani, A.R.1    Harvey, C.J.2    Cosgrove, D.O.3
  • 57
    • 8844287508 scopus 로고    scopus 로고
    • Imaging in antiangiogenesis trial: A clinical trials radiology perspective
    • Kothari M, Guermazi A, White D, Suhy J, Reinhold C. Imaging in antiangiogenesis trial: A clinical trials radiology perspective. Br J Radiol 2003; 76 (Spec No 1): S92-96.
    • (2003) Br J Radiol , vol.76 , Issue.1
    • Kothari, M.1    Guermazi, A.2    White, D.3    Suhy, J.4    Reinhold, C.5
  • 59
    • 0036794518 scopus 로고    scopus 로고
    • Dynamic contrast enhanced MRI in clinical oncology: Current status and future directions
    • Padhani AR. Dynamic contrast enhanced MRI in clinical oncology: Current status and future directions. J Magn Reson Imaging 2002; 16(4): 407-22.
    • (2002) J Magn Reson Imaging , vol.16 , Issue.4 , pp. 407-422
    • Padhani, A.R.1
  • 60
    • 0035428054 scopus 로고    scopus 로고
    • Dynamic contrast enhanced MRI studies in oncology with an emphasis on quantification, validation and human studies
    • Padhani AR, Husband JE. Dynamic contrast enhanced MRI studies in oncology with an emphasis on quantification, validation and human studies. Clin Radiol 2001; 56(8): 607-20.
    • (2001) Clin Radiol , vol.56 , Issue.8 , pp. 607-620
    • Padhani, A.R.1    Husband, J.E.2
  • 61
    • 77953856505 scopus 로고    scopus 로고
    • Bevacizumab induced tumor vessel remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation
    • Myers AL, Williams RF, Ng CY, Hartwich JE, Davidoff AM. Bevacizumab induced tumor vessel remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation. J Pediatr Surg 2010; 45(6): 1080-5.
    • (2010) J Pediatr Surg , vol.45 , Issue.6 , pp. 1080-1085
    • Myers, A.L.1    Williams, R.F.2    Ng, C.Y.3    Hartwich, J.E.4    Davidoff, A.M.5
  • 62
    • 0031038068 scopus 로고    scopus 로고
    • Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
    • Relf M, LeJeune S, Scott PA, Fox S, Smith K, Leek R, et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997; 57(5): 963-69.
    • (1997) Cancer Res , vol.57 , Issue.5 , pp. 963-969
    • Relf, M.1    Lejeune, S.2    Scott, P.A.3    Fox, S.4    Smith, K.5    Leek, R.6
  • 63
    • 3242678011 scopus 로고    scopus 로고
    • Patterns of care in radiotherapy of breast cancer in Austria 1985: Data acquisition and comparison with data of US-PCS 1983
    • Mayer R, Handl-Zeller L, Quehenberger F, Hammer J, Kametriser G, Kolbabek H, et al. Patterns of care in radiotherapy of breast cancer in Austria 1985: Data acquisition and comparison with data of US-PCS 1983. Radiother Oncol 2004; 72(1): 45-51.
    • (2004) Radiother Oncol , vol.72 , Issue.1 , pp. 45-51
    • Mayer, R.1    Handl-Zeller, L.2    Quehenberger, F.3    Hammer, J.4    Kametriser, G.5    Kolbabek, H.6
  • 64
    • 0141625688 scopus 로고    scopus 로고
    • Angiogenesis inhibitors and hypoxia
    • Kieran MW, Folkman J, Heymach J. Angiogenesis inhibitors and hypoxia. Nat Med 2003; 9(9):1104-5.
    • (2003) Nat Med , vol.9 , Issue.9 , pp. 1104-1105
    • Kieran, M.W.1    Folkman, J.2    Heymach, J.3
  • 65
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10(8): 789-99.
    • (2004) Nat Med , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 66
    • 6344253429 scopus 로고    scopus 로고
    • Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents
    • Dang LH, Bettegowda C, Agrawal N, Cheong I, Huso D, Frost P, et al. Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents. Cancer Biol Ther 2004; 3(3): 326-37.
    • (2004) Cancer Biol Ther , vol.3 , Issue.3 , pp. 326-337
    • Dang, L.H.1    Bettegowda, C.2    Agrawal, N.3    Cheong, I.4    Huso, D.5    Frost, P.6
  • 67
    • 0034048358 scopus 로고    scopus 로고
    • Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
    • Hanahan D, Bergers G, Bergsland E. Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J Clin Invest 2000; 105(8): 1045-7.
    • (2000) J Clin Invest , vol.105 , Issue.8 , pp. 1045-1047
    • Hanahan, D.1    Bergers, G.2    Bergsland, E.3
  • 68
    • 77949275202 scopus 로고    scopus 로고
    • Use of anti-VEGF adjuvant therapy in cancer: Challenges and rationale
    • Bagri A, Kouros-Mehr H, Leong KG, Plowman GD. Use of anti-VEGF adjuvant therapy in cancer: Challenges and rationale. Trends Mol Med 2010; 16(3): 122-32.
    • (2010) Trends Mol Med , vol.16 , Issue.3 , pp. 122-132
    • Bagri, A.1    Kouros-Mehr, H.2    Leong, K.G.3    Plowman, G.D.4


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