Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype

Cancer Research

Volumn 74, Issue 10, 2014, Pages 2869-2881

  Zhang, Zhaocheng ^a   Dong, Zhihong ^a   Lauxen, Isabel S ^d   Filho, Manoel Sant'Ana ^d   Nör, Jacques E ^a,b,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b University of Michigan   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; DESMOPLAKIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HERMES ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; PROTEIN KINASE B; STAT3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DISTANT METASTASIS; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA CELL LINE; TUMOR GROWTH; UPREGULATION;

AGED; ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL COMMUNICATION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL MOVEMENT; ENDOTHELIAL CELLS; EPIDERMAL GROWTH FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; HEAD AND NECK NEOPLASMS; HETEROGRAFTS; HUMANS; MALE; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84901267967     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-2032     Document Type: Article

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