Miltefosine increases lipid and protein dynamics in leishmania amazonensis membranes at concentrations similar to those needed for cytotoxicity activity

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 6, 2014, Pages 3021-3028

  Moreira, Rodrigo Alves ^a   Mendanha, Sebastião Antonio ^a   Fernandes, Kelly Souza ^a   Matos, Grazzielle Guimaraes ^a   Alonso, Lais ^a   Dorta, Miriam Leandro ^a   Alonso, Antonio ^a  

^a FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; LIPID; MALEIMIDE; MEMBRANE PROTEIN; MILTEFOSINE; POLYPEPTIDE; PROTOZOAL PROTEIN; THIOL GROUP; ANTINEOPLASTIC AGENT; MEMBRANE LIPID; MICELLE; PHOSPHORYLCHOLINE; SPIN LABEL;

ARTICLE; CELL DEATH; CELL GROWTH; CELL MEMBRANE; CELL VIABILITY; CYTOLYSIS; DRUG CYTOTOXICITY; ELECTRON SPIN RESONANCE; GROWTH INHIBITION; HYDROGEN BOND; HYDROPHOBICITY; LEISHMANIA; MEMBRANE FLUIDITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN CONFORMATION; SPIN LABELING; STRATUM CORNEUM; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; HUMAN; LEISHMANIA MEXICANA; METABOLISM; MICELLE;

ANTINEOPLASTIC AGENTS; CELL MEMBRANE; CELL SURVIVAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LEISHMANIA MEXICANA; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MICELLES; MOLECULAR DYNAMICS SIMULATION; PHOSPHORYLCHOLINE; PROTEIN CONFORMATION; SPIN LABELS;

EID: 84901258811     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01332-13     Document Type: Article

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