메뉴 건너뛰기




Volumn 14, Issue 3, 2014, Pages 272-280

Providing patients with pharmacogenetic test results affects adherence to statin therapy: Results of the Additional KIF6 Risk Offers Better Adherence to Statins (AKROBATS) trial

Author keywords

KIF6; medication adherence; pharmacogenetics; statin therapy

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 84901255199     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2013.27     Document Type: Article
Times cited : (32)

References (48)
  • 1
    • 84855353573 scopus 로고    scopus 로고
    • On behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics - 2012 update: A report from the American Heart Association
    • Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB et al. on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics - 2012 update: a report from the American Heart Association. Circulation 2012; 125: e12-e230.
    • (2012) Circulation , vol.125
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3    Benjamin, E.J.4    Berry, J.D.5    Borden, W.B.6
  • 2
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel iii) final report. PMID: 12485966
    • Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel iii) final report. Circulation 2002; 106: 3143-3421; PMID: 12485966.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 3
    • 4544275379 scopus 로고    scopus 로고
    • For the Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • Grundy SM, Cleeman JI, Merz CNB, Brewer Jr. HB, Clark LT, Hunninghake DB et al. for the Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. JACC 2004; 44: 720-732.
    • (2004) JACC , vol.44 , pp. 720-732
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.B.3    Brewer Jr., H.B.4    Clark, L.T.5    Hunninghake, D.B.6
  • 4
    • 84855185039 scopus 로고    scopus 로고
    • Standards of Medical Care in Diabetes - 2012
    • American Diabetes Association
    • American Diabetes Association. Standards of Medical Care in Diabetes - 2012. Diabetes Care 2012; 35(Suppl 1): S11-S63.
    • (2012) Diabetes Care , vol.35 , Issue.SUPPL. 1
  • 5
    • 82355175158 scopus 로고    scopus 로고
    • AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: A guideline from the American Heart Association and American College of Cardiology Foundation
    • Smith Jr SC, Benjamin EJ, Bonow RO, Braun LT, Creagerm M, Franklin BA et al. AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation 2011; 124: 2458-2473.
    • (2011) Circulation , vol.124 , pp. 2458-2473
    • Smith Jr., S.C.1    Benjamin, E.J.2    Bonow, R.O.3    Braun, L.T.4    Creagerm, M.5    Franklin, B.A.6
  • 6
    • 84901280246 scopus 로고    scopus 로고
    • 2011 Top Therapeutic Classes by US Spending, IMS Health2012 Accessed
    • 2011 Top Therapeutic Classes by US Spending, IMS Health2012 http://www. imshealth.com/deployedfiles/ims/Global/Content/Corporate/PressRoom/Top-Line MarketData&Trends/2011Top-lineMarketData/Top-Therapy-Classes-by-Sales. pdfAccessed 2012.
    • (2012)
  • 7
    • 84901249309 scopus 로고    scopus 로고
    • 2011 Top Therapeutic Classes by U.S. Dispensed Prescriptions, IMS Health Accessed on 2012
    • 2011 Top Therapeutic Classes by U.S. Dispensed Prescriptions, IMS Health 2012 http://www.imshealth.com/deployedfiles/ims/Global/Content/Corporate/Press Room/Top-LineMarketData&Trends/2011ToplineMarketData/Top-Therapy-Classes-by- RX.pdfAccessed on 2012.
    • (2012)
  • 8
    • 33947217299 scopus 로고    scopus 로고
    • Achievement of optimal combined lipid values in a managed care setting: Is a new treatment paradigm needed?
    • Sarawate CA, Cziraky MJ, Stanek EJ, Willey VJ, Corbelli JC, Charland SL. Achievement of optimal combined lipid values in a managed care setting: is a new treatment paradigm needed? Cin Ther 2007; 29: 196-209.
    • (2007) Cin Ther , vol.29 , pp. 196-209
    • Sarawate, C.A.1    Cziraky, M.J.2    Stanek, E.J.3    Willey, V.J.4    Corbelli, J.C.5    Charland, S.L.6
  • 9
    • 0037167013 scopus 로고    scopus 로고
    • Adherence with statins in elderly patients with and without acute coronary syndromes
    • Jackevicius CA, Mamdani M, Tu JV. Adherence with statins in elderly patients with and without acute coronary syndromes. JAMA 2002; 288: 462-467.
    • (2002) JAMA , vol.288 , pp. 462-467
    • Jackevicius, C.A.1    Mamdani, M.2    Tu, J.V.3
  • 10
    • 78649678941 scopus 로고    scopus 로고
    • The effects of adherence and persistence on clinical outcomes in patients treated with statins: A systematic review
    • Simpson RJ, Mendys P. The effects of adherence and persistence on clinical outcomes in patients treated with statins: A systematic review. J Clin Lipidol 2010; 4: 462-471.
    • (2010) J Clin Lipidol , vol.4 , pp. 462-471
    • Simpson, R.J.1    Mendys, P.2
  • 11
    • 20544460816 scopus 로고    scopus 로고
    • Impact of medication adherence on hospitalization risk and healthcare cost
    • Sokol MC, McGuigan KA, Verbrugge RR, Epstein RS. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care 2005; 43: 521-530.
    • (2005) Med Care , vol.43 , pp. 521-530
    • Sokol, M.C.1    McGuigan, K.A.2    Verbrugge, R.R.3    Epstein, R.S.4
  • 12
    • 77954102849 scopus 로고    scopus 로고
    • Is there a relationship between early statin compliance and a reduction in healthcare utilization?
    • Aubert RE, Yao J, Xia F, Garavaglia SB. Is there a relationship between early statin compliance and a reduction in healthcare utilization? Am J Managed Care 2010; 16: 459-466.
    • (2010) Am J Managed Care , vol.16 , pp. 459-466
    • Aubert, R.E.1    Yao, J.2    Xia, F.3    Garavaglia, S.B.4
  • 13
    • 79956117633 scopus 로고    scopus 로고
    • Adherence to statins, subsequent healthcare costs, and cardiovascular hospitalizations
    • Pittman DG, Chen W, Bowlin SJ, Foody JM. Adherence to statins, subsequent healthcare costs, and cardiovascular hospitalizations. Am J Cardiol. 2011; 107: 1662-1666.
    • (2011) Am J Cardiol. , vol.107 , pp. 1662-1666
    • Pittman, D.G.1    Chen, W.2    Bowlin, S.J.3    Foody, J.M.4
  • 14
    • 79959370948 scopus 로고    scopus 로고
    • Medication adherence, comorbidities, and health risk impacts on workforce absence and job performance
    • Loeppke R, Haufle V, Jinnett K, Parry T, Zhu J, Hymel P et al. Medication adherence, comorbidities, and health risk impacts on workforce absence and job performance. JOEM 2011; 53: 595-604.
    • (2011) JOEM , vol.53 , pp. 595-604
    • Loeppke, R.1    Haufle, V.2    Jinnett, K.3    Parry, T.4    Zhu, J.5    Hymel, P.6
  • 15
    • 84901272981 scopus 로고    scopus 로고
    • National council on patient information and education. Enhancing prescription medicine adherence: A National Action Plan. 2007 Accessed on November 12
    • National council on patient information and education. Enhancing prescription medicine adherence: A National Action Plan. 2007 http://www.talkaboutrx. org/documents/enhancing-prescription-medicine-adherence. pdf Accessed on November 12, 2012.
    • (2012)
  • 17
    • 67649523031 scopus 로고    scopus 로고
    • Medication adherence Its importance in cardiovascular disease
    • Ho PM, Bryson CL, Rumsfeld JS. Medication adherence. Its importance in cardiovascular disease. Circulation 2009; 119: 3028-3035.
    • (2009) Circulation , vol.119 , pp. 3028-3035
    • Ho, P.M.1    Bryson, C.L.2    Rumsfeld, J.S.3
  • 19
    • 34047115813 scopus 로고    scopus 로고
    • Interventions to enhance medication adherence in chronic medical conditions
    • Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions. Arch Int Med 2007; 167: 540-545.
    • (2007) Arch Int Med , vol.167 , pp. 540-545
    • Kripalani, S.1    Yao, X.2    Haynes, R.B.3
  • 20
    • 33845450660 scopus 로고    scopus 로고
    • Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol
    • Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol. JAMA 2006; 296: 2563-2571.
    • (2006) JAMA , vol.296 , pp. 2563-2571
    • Lee, J.K.1    Grace, K.A.2    Taylor, A.J.3
  • 21
    • 82555192222 scopus 로고    scopus 로고
    • Genomics of cardiovascular disease
    • O'Donnell CJ, Nabel EG. Genomics of cardiovascular disease. N Engl J Med 2011; 365: 2098-2109.
    • (2011) N Engl J Med , vol.365 , pp. 2098-2109
    • O'donnell, C.J.1    Nabel, E.G.2
  • 23
    • 77956947971 scopus 로고    scopus 로고
    • KIF6 polymorphism as a predictor of risk of coronary events and clinical event reduction by statins
    • Li Y, Iakoubova OA, Shiffman D, Devlin JJ, Forrester JS, Superko HR. KIF6 polymorphism as a predictor of risk of coronary events and clinical event reduction by statins. Am J Cardiol 2010; 106: 994-998.
    • (2010) Am J Cardiol , vol.106 , pp. 994-998
    • Li, Y.1    Iakoubova, O.A.2    Shiffman, D.3    Devlin, J.J.4    Forrester, J.S.5    Superko, H.R.6
  • 24
    • 83755186157 scopus 로고    scopus 로고
    • A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: Two meta-analyses and a meta-regression analysis
    • Ference BA, Yoo W, Flack JM, Clarke M. A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis. PloS One 6: e28834.
    • PloS One , vol.6
    • Ference, B.A.1    Yoo, W.2    Flack, J.M.3    Clarke, M.4
  • 25
    • 80755125639 scopus 로고    scopus 로고
    • Genomic information as a behavioral health intervention: Can it work?
    • Bloss CS, Madlensky L, Schork NJ, Topol EJ. Genomic information as a behavioral health intervention: can it work? Pers Med 2011; 8: 659-667.
    • (2011) Pers Med , vol.8 , pp. 659-667
    • Bloss, C.S.1    Madlensky, L.2    Schork, N.J.3    Topol, E.J.4
  • 26
    • 38149036642 scopus 로고    scopus 로고
    • A systematic review of perceived risks, psychological and behavioral impacts of genetic testing
    • Heshka JT, Palleschi C, Howley H, Wilson B, Wells PS. A systematic review of perceived risks, psychological and behavioral impacts of genetic testing. Genet Med 2008; 10: 19-32.
    • (2008) Genet Med , vol.10 , pp. 19-32
    • Heshka, J.T.1    Palleschi, C.2    Howley, H.3    Wilson, B.4    Wells, P.S.5
  • 29
    • 0030096228 scopus 로고    scopus 로고
    • A 12-item Short Form health survey: Construction of scales and preliminary tests of reliability and validity
    • Ware JE, Kosiniski M, Keller SD. A 12-item Short Form health survey: Construction of scales and preliminary tests of reliability and validity. Med Care 1996; 34: 220-233.
    • (1996) Med Care , vol.34 , pp. 220-233
    • Ware, J.E.1    Kosiniski, M.2    Keller, S.D.3
  • 30
    • 0022632510 scopus 로고
    • Concurrent predictive validity of a self-reported measure of medication adherence
    • Morisky DE, Green LW, Levine DM. Concurrent predictive validity of a self-reported measure of medication adherence. Med Care 1986; 24: 67-74.
    • (1986) Med Care , vol.24 , pp. 67-74
    • Morisky, D.E.1    Green, L.W.2    Levine, D.M.3
  • 31
    • 0034090681 scopus 로고    scopus 로고
    • High-throughput SNP allele frequency determination in pooled DNA samples by kinetic PCR
    • Germer S, Holland MJ, Higuchi R. High-throughput SNP allele frequency determination in pooled DNA samples by kinetic PCR. Genome Res 2000; 10: 258-266.
    • (2000) Genome Res , vol.10 , pp. 258-266
    • Germer, S.1    Holland, M.J.2    Higuchi, R.3
  • 32
    • 55649116938 scopus 로고    scopus 로고
    • As empirical bases for standardizing adherence measures derived from administrative claims data among diabetic patients
    • Karve S, Cleves MA, Helm M, Hudson TJ, West DS, Martin BC. As empirical bases for standardizing adherence measures derived from administrative claims data among diabetic patients. Med Care 2008; 46: 1125-1133.
    • (2008) Med Care , vol.46 , pp. 1125-1133
    • Karve, S.1    Cleves, M.A.2    Helm, M.3    Hudson, T.J.4    West, D.S.5    Martin, B.C.6
  • 34
    • 69849097352 scopus 로고    scopus 로고
    • Good and poor adherence: Optimal cut-point for adherence measures using administrative claims data
    • Karve S, Cleves MA, Helm M, Hudson TJ, West DS, Martin BC. Good and poor adherence: optimal cut-point for adherence measures using administrative claims data. CMRO 2009; 25: 2303-2310.
    • (2009) CMRO , vol.25 , pp. 2303-2310
    • Karve, S.1    Cleves, M.A.2    Helm, M.3    Hudson, T.J.4    West, D.S.5    Martin, B.C.6
  • 35
    • 0036280883 scopus 로고    scopus 로고
    • Incorporating genetic suseptability feedback into a smoking cessation program for African- American smokers with low income
    • McBride CM, Bepler G, Lipkus IM, Lyna P, Samsa G, Albright J et al. Incorporating genetic suseptability feedback into a smoking cessation program for African- American smokers with low income. Cancer Epi Biomark Prev 2002; 11: 521-528.
    • (2002) Cancer Epi Biomark Prev , vol.11 , pp. 521-528
    • McBride, C.M.1    Bepler, G.2    Lipkus, I.M.3    Lyna, P.4    Samsa, G.5    Albright, J.6
  • 36
    • 79851493086 scopus 로고    scopus 로고
    • Effect of direct-to-consumer genomewide profiling to assess disease risk
    • Bloss CS, Schork NJ, Topol EJ. Effect of direct-to-consumer genomewide profiling to assess disease risk. NEJM 2011; 364: 524-534.
    • (2011) NEJM , vol.364 , pp. 524-534
    • Bloss, C.S.1    Schork, N.J.2    Topol, E.J.3
  • 37
    • 69549083158 scopus 로고    scopus 로고
    • Evaluating the utility of personal genomic information
    • Foster MW, Mulvihill JJ, Sharp RR. Evaluating the utility of personal genomic information. Genet Med 2009; 11: 570-574.
    • (2009) Genet Med , vol.11 , pp. 570-574
    • Foster, M.W.1    Mulvihill, J.J.2    Sharp, R.R.3
  • 38
    • 8344246958 scopus 로고    scopus 로고
    • Follow-up lipid tests and physician visits are associated with improved adherence to statin therapy
    • Benner JS, Tiece JC, Ballantyne CM, Prasad C, Bullano MF, Willey VJ et al. Follow-up lipid tests and physician visits are associated with improved adherence to statin therapy. Pharmacoeconomics 2004; 22(Suppl 3): 13-23.
    • (2004) Pharmacoeconomics , vol.22 , Issue.SUPPL. 3 , pp. 13-23
    • Benner, J.S.1    Tiece, J.C.2    Ballantyne, C.M.3    Prasad, C.4    Bullano, M.F.5    Willey, V.J.6
  • 39
    • 41949127115 scopus 로고    scopus 로고
    • A randomized trial of direct-to-patient communication to enhance adherence to b-blocker therapy following myocardial infarction
    • Smith DH, Kramer JM, Perrin N, Platt R, Roblin DW, Land K et al. A randomized trial of direct-to-patient communication to enhance adherence to b-blocker therapy following myocardial infarction. Arch Int Med 2008; 168: 477-483.
    • (2008) Arch Int Med , vol.168 , pp. 477-483
    • Smith, D.H.1    Kramer, J.M.2    Perrin, N.3    Platt, R.4    Roblin, D.W.5    Land, K.6
  • 41
    • 38349118892 scopus 로고    scopus 로고
    • Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: The CARE and WOSCOPS trials
    • Iakoubova OA, Tong CH, Rowland CM, Kirchgessner TG, Young BA, Arellano AR et al. Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. J Am Coll Cardiol 2008; 51: 435-443.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 435-443
    • Iakoubova, O.A.1    Tong, C.H.2    Rowland, C.M.3    Kirchgessner, T.G.4    Young, B.A.5    Arellano, A.R.6
  • 42
    • 38349171836 scopus 로고    scopus 로고
    • Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: Results from the PROVE IT-TIMI 22 study
    • Iakoubova OA, Sabatine MS, Rowland CM, Tong CH, Catanese JJ, Ranade K et al. Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study. J Am Coll Cardiol 2008; 51: 449-455.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 449-455
    • Iakoubova, O.A.1    Sabatine, M.S.2    Rowland, C.M.3    Tong, C.H.4    Catanese, J.J.5    Ranade, K.6
  • 43
    • 77950864702 scopus 로고    scopus 로고
    • Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial
    • Shiffman D, Sabatine MS, Louie JZ, Kirchgessner TG, Iakoubova OA, Campos H et al. Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial. Am J Cardiol 2010; 105: 1300-1305.
    • (2010) Am J Cardiol , vol.105 , pp. 1300-1305
    • Shiffman, D.1    Sabatine, M.S.2    Louie, J.Z.3    Kirchgessner, T.G.4    Iakoubova, O.A.5    Campos, H.6
  • 44
    • 78049327781 scopus 로고    scopus 로고
    • Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies
    • Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF et al. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. JACC 2010; 56: 1552-1563.
    • (2010) JACC , vol.56 , pp. 1552-1563
    • Assimes, T.L.1    Hólm, H.2    Kathiresan, S.3    Reilly, M.P.4    Thorleifsson, G.5    Voight, B.F.6
  • 45
    • 79955875125 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study Collaborative Group. No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study
    • Hopewell JC, Parish S, Clarke R, Armitage J, Bowman L, Hager J et al. MRC/BHF Heart Protection Study Collaborative Group. No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study. J Am Coll Cardiol 2011; 57: 2000-2007.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 2000-2007
    • Hopewell, J.C.1    Parish, S.2    Clarke, R.3    Armitage, J.4    Bowman, L.5    Hager, J.6
  • 47
    • 84860858410 scopus 로고    scopus 로고
    • On behalf of the TNT and IDEAL Investigators. The 719Arg variant of KIF6 and cardiovascular outcomes in statin-treated, stable coronary patients of the treating to new targets and incremental decrease in end points through aggressive lipidlowering prospective studies
    • Arsenault BJ, Boekholdt SM, Hovingh GK, Hyde CL, Demicco DA, Chatterjee A et al. on behalf of the TNT and IDEAL Investigators. The 719Arg variant of KIF6 and cardiovascular outcomes in statin-treated, stable coronary patients of the treating to new targets and incremental decrease in end points through aggressive lipidlowering prospective studies. Circ Cardiovasc Genet 2012; 5: 51-57.
    • (2012) Circ Cardiovasc Genet , vol.5 , pp. 51-57
    • Arsenault, B.J.1    Boekholdt, S.M.2    Hovingh, G.K.3    Hyde, C.L.4    Demicco, D.A.5    Chatterjee, A.6
  • 48
    • 80052485513 scopus 로고    scopus 로고
    • Importance of including early nonadherence in estimates of medication adherence
    • Raebel MA, Carrolll NM, Schroeder EB, Bayliss EA. Importance of including early nonadherence in estimates of medication adherence. Ann Pharmacother 2011; 45: 1053-1060.
    • (2011) Ann Pharmacother , vol.45 , pp. 1053-1060
    • Raebel, M.A.1    Carrolll, N.M.2    Schroeder, E.B.3    Bayliss, E.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.