Adherence to statins, subsequent healthcare costs, and cardiovascular hospitalizations

American Journal of Cardiology

Volumn 107, Issue 11, 2011, Pages 1662-1666

  Pittman, Donald G ^a   Chen, William ^a   Bowlin, Steven J ^a   Foody, Joanne M ^b  

^a Medco Research Institute LLC   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; FEMALE; HEALTH CARE COST; HOSPITALIZATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PHARMACY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STROKE;

ADOLESCENT; ADULT; FEMALE; HEALTH CARE COSTS; HOSPITALIZATION; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 79956117633     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2011.01.052     Document Type: Article

References (21)

1. P.M. Ho, C.L. Bryson, and J.S. Rumsfeld Medication adherenceits importance in cardiovascular outcomes Circulation 119 2009 3028 3035
2. M. Hudson, E. Rhame, H. Richard, and L. Pilote Comparison of measures of medication persistency using prescription drug database Am Heart J 153 2007 59 65 (Pubitemid 44880894)
3. P.W. Choo, C.S. Rand, T.S. Inui, M.L. Lee, E. Cain, M. Cordeiro-Breault, C. Canning, and R. Platt Validation of patient reports, automated pharmacy records, and pill counts with electronic monitoring of adherence to antihypertensive therapy Med Care 37 1999 846 857
4. D. Mann, and K. Reynolds Trends in statin Use and low-density lipoprotein cholesterol Levels among US Adults: Impact of the 2001 National Cholesterol Education Program Guidelines Ann Pharmacother 42 2008 1205 1215
5. C.A. Jackevicius, M. Mamdani, and J.V. Tu Adherence with statin therapy in elderly patients with and without acute coronary syndromes JAMA 288 2002 462 467 (Pubitemid 34787477)
6. J.P. Frolkis, G.L. Pearce, V. Nambi, S. Minor, and D.L. Sprecher Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice Am J Med 113 2002 625 629 (Pubitemid 36015797)
7. J.N. Rasmussen, A. Chong, and D.A. Alter Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction JAMA 297 2007 177 186 (Pubitemid 46089734)
8. P.M. Ho, D.J. Magid, S.M. Shetterly, K.L. Olson, T.M. Maddox, P.N. Peterson, F.A. Masoudi, and J.S. Rumsfeld Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease Am Heart J 155 2008 772 779 (Pubitemid 351410514)
9. D.P. Goldman, G.F. Joyce, and P. Karaca-Mandic Varying pharmacy benefits with clinical status: the case of cholesterol-lowering therapy Am J Manag Care 12 2006 21 28 (Pubitemid 43139537)
10. R.E. Aubert, J. Yao, F. Xia, and S.B. Garavaglia Is there a relationship between early statin compliance and a reduction in healthcare utilization? Am J Manag Care 16 2010 101 109
11. A.M. Peterson, and W.F. McGhan Pharmacoeconomic Impact of non-compliance with statins Pharmacoeconomics 23 2005 13 25
12. M.C. Sokol, K.A. McGuigan, R.R. Verbrugge, and R.S. Epstein Impact of medication adherence on hospitalization risk and healthcare cost Med Care 43 2005 521 530 (Pubitemid 40847288)
13. L.M. Hess, M.A. Raebel, D.A. Conner, and D.C. Malone Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures Ann Pharmacother 40 2006 1280 1288 (Pubitemid 44204957)
14. L. Osterberg, and T. Blaschke Adherence to medication N Engl J Med 353 2005 487 497 (Pubitemid 41127293)
15. D.E. Morisky, L.W. Green, and D.M. Levine Concurrent and predictive validity of a self reported measure of medication adherence Med Care 24 1986 67 74 (Pubitemid 16125389)
16. B. McGinnis, K.L. Olson, D. Magid, E. Bayliss, E.J. Korner, D.W. Brand, and J.F. Steiner Factors related to adherence to statin therapy Ann Pharmacother 41 2007 1805 1811 (Pubitemid 350044342)
17. T.B. Gibson, T.L. Mark, K. Axelsen, O. Baser, D.A. Rublee, and K.A. McGuigan Impact on statin copayments on adherence and medical care utilization and expenditures Am J Manag Care 12 2006 SP11 SP19
18. N.K. Choudhry, A.R. Patrick, E.M. Antman, J. Avorn, and W.H. Shrank Cost-effectiveness of providing full drug coverage to increase medication adherence in post-myocardial infarction Medicare beneficiaries Circulation 117 2008 1261 1268 (Pubitemid 351365674)
19. S. Schneeweiss, A.R. Patrick, M. Maclure, C.R. Dormuth, and R.J. Glynn Adherence to statin therapy under drug cost sharing in patients with and without acute myocardial infarction: a population-based natural experiment Circulation 115 2007 2128 2135 (Pubitemid 46659064)
20. J.J. Ellis, S.R. Erickson, J.G. Stevenson, S.J. Bernstein, R.A. Stiles, and A.M. Fendrick Suboptimal statin adherence and discontinuation in primary and secondary prevention populations: should we target patients with the most to gain? J Gen Intern Med 19 2004 638 645 (Pubitemid 38803154)
21. M.A. Brookhart, A.R. Patrick, C. Dormuth, J. Avorn, W. Shrank, S.M. Cadarette, and D.H. Solomon Adherence to lipid-lowering therapy and the use of preventive health services: an investigation of the healthy user effect Am J Epidemiol 166 2007 348-335