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Volumn 6, Issue 12, 2011, Pages

A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: Two meta-analyses and a meta-regression analysis

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; TRYPTOPHAN; KIF6 PROTEIN, HUMAN; KINESIN;

EID: 83755186157     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028834     Document Type: Article
Times cited : (28)

References (35)
  • 1
    • 38349118892 scopus 로고    scopus 로고
    • Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials
    • Iakoubova OA, Tong CH, Rowland CM, Kirchgessner TG, Young BA, et al. (2008) Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. J Am Coll Cardiol 51 (4): 435-443.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.4 , pp. 435-443
    • Iakoubova, O.A.1    Tong, C.H.2    Rowland, C.M.3    Kirchgessner, T.G.4    Young, B.A.5
  • 2
    • 77950864702 scopus 로고    scopus 로고
    • Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial
    • Shiffman D, Sabatine MS, Louie JZ, Kirchgessner TG, Iakoubova OA, et al. (2010) Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial. Am J Cardiol 105 (9): 1300-1305.
    • (2010) Am J Cardiol , vol.105 , Issue.9 , pp. 1300-1305
    • Shiffman, D.1    Sabatine, M.S.2    Louie, J.Z.3    Kirchgessner, T.G.4    Iakoubova, O.A.5
  • 3
    • 38349171836 scopus 로고    scopus 로고
    • Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study
    • Iakoubova OA, Sabatine MS, Rowland CM, Tong CH, Catanese JJ, et al. (2008) Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study. J Am Coll Cardiol 51 (4): 449-455.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.4 , pp. 449-455
    • Iakoubova, O.A.1    Sabatine, M.S.2    Rowland, C.M.3    Tong, C.H.4    Catanese, J.J.5
  • 4
    • 77955467684 scopus 로고    scopus 로고
    • KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study
    • Iakoubova OA, Robertson M, Tong CH, Rowland CM, Catanese JJ, et al. (2010) KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study. Eur J Cardiovasc Prev Rehabil 17 (4): 455-461.
    • (2010) Eur J Cardiovasc Prev Rehabil , vol.17 , Issue.4 , pp. 455-461
    • Iakoubova, O.A.1    Robertson, M.2    Tong, C.H.3    Rowland, C.M.4    Catanese, J.J.5
  • 5
    • 79955875125 scopus 로고    scopus 로고
    • No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study. MRC/BHF Heart Protection Study Collaborative Group
    • Hopewell JC, Parish S, Clarke R, Armitage J, Bowman L, et al. (2011) No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study. MRC/BHF Heart Protection Study Collaborative Group. J Am Coll Cardiol 57 (20): 2000-2007.
    • (2011) J Am Coll Cardiol , vol.57 , Issue.20 , pp. 2000-2007
    • Hopewell, J.C.1    Parish, S.2    Clarke, R.3    Armitage, J.4    Bowman, L.5
  • 6
    • 80052762422 scopus 로고    scopus 로고
    • Kinesin-Like Protein 6 (KIF6) Polymorphism and the Efficacy of Rosuvastatin in Primary Prevention
    • Ridker PM, Macfadyen JG, Glynn RJ, Chasman DI, (2011) Kinesin-Like Protein 6 (KIF6) Polymorphism and the Efficacy of Rosuvastatin in Primary Prevention. Circ Cardiovasc Genet 4 (3): 312-317.
    • (2011) Circ Cardiovasc Genet , vol.4 , Issue.3 , pp. 312-317
    • Ridker, P.M.1    Macfadyen, J.G.2    Glynn, R.J.3    Chasman, D.I.4
  • 8
    • 77956947971 scopus 로고    scopus 로고
    • A KIF6 polymorphism as a predictor of risk of coronary events and of clinical event reduction by statin therapy
    • Li Y, Iakoubova OA, Shiffman D, Devlin JJ, Forrester JS, et al. (2010) A KIF6 polymorphism as a predictor of risk of coronary events and of clinical event reduction by statin therapy. Am J Cardiol 106 (7): 994-998.
    • (2010) Am J Cardiol , vol.106 , Issue.7 , pp. 994-998
    • Li, Y.1    Iakoubova, O.A.2    Shiffman, D.3    Devlin, J.J.4    Forrester, J.S.5
  • 9
    • 78651257949 scopus 로고    scopus 로고
    • Genetic variants in the KIF6 region and coronary event reduction from statin therapy
    • Li Y, Sabatine MS, Tong CH, Ford I, Kirchgessner TG, et al. (2011) Genetic variants in the KIF6 region and coronary event reduction from statin therapy. Hum Genet 129 (1): 17-23.
    • (2011) Hum Genet , vol.129 , Issue.1 , pp. 17-23
    • Li, Y.1    Sabatine, M.S.2    Tong, C.H.3    Ford, I.4    Kirchgessner, T.G.5
  • 10
    • 34547555885 scopus 로고    scopus 로고
    • Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study
    • Morrison AC, Bare LA, Chambless LE, Ellis SG, Malloy M, et al. (2007) Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol 166 (1): 28-35.
    • (2007) Am J Epidemiol , vol.166 , Issue.1 , pp. 28-35
    • Morrison, A.C.1    Bare, L.A.2    Chambless, L.E.3    Ellis, S.G.4    Malloy, M.5
  • 11
    • 37349008521 scopus 로고    scopus 로고
    • Five common gene variants identify elevated genetic risk for coronary heart disease
    • Bare LA, Morrison AC, Rowland CM, Shiffman D, Luke MM, et al. (2007) Five common gene variants identify elevated genetic risk for coronary heart disease. Genet Med 9 (10): 682-689.
    • (2007) Genet Med , vol.9 , Issue.10 , pp. 682-689
    • Bare, L.A.1    Morrison, A.C.2    Rowland, C.M.3    Shiffman, D.4    Luke, M.M.5
  • 12
    • 37549058754 scopus 로고    scopus 로고
    • Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study
    • Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, et al. (2008) Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol 28 (1): 173-179.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.1 , pp. 173-179
    • Shiffman, D.1    O'Meara, E.S.2    Bare, L.A.3    Rowland, C.M.4    Louie, J.Z.5
  • 13
    • 38349130543 scopus 로고    scopus 로고
    • A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study
    • Shiffman D, Chasman DI, Zee RY, Iakoubova OA, Louie JZ, et al. (2008) A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study. J Am Coll Cardiol 51 (4): 444-448.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.4 , pp. 444-448
    • Shiffman, D.1    Chasman, D.I.2    Zee, R.Y.3    Iakoubova, O.A.4    Louie, J.Z.5
  • 14
    • 78049327781 scopus 로고    scopus 로고
    • Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies
    • Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, et al. (2010) Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol 56 (19): 1552-1563.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.19 , pp. 1552-1563
    • Assimes, T.L.1    Hólm, H.2    Kathiresan, S.3    Reilly, M.P.4    Thorleifsson, G.5
  • 16
    • 80052145719 scopus 로고    scopus 로고
    • Checking reference lists to find additional studies for systematic reviews
    • Horsley T, Dingwall O, Sampson M, (2011) Checking reference lists to find additional studies for systematic reviews. Cochrane Database Syst Rev 8: MR000026.
    • (2011) Cochrane Database Syst Rev , vol.8
    • Horsley, T.1    Dingwall, O.2    Sampson, M.3
  • 17
    • 12144283900 scopus 로고    scopus 로고
    • Obstacles and opportunities in meta-analysis of genetic association studies
    • Salanti G, Sanderson S, Higgins JP, (2005) Obstacles and opportunities in meta-analysis of genetic association studies. Genet Med 7 (1): 13-20.
    • (2005) Genet Med , vol.7 , Issue.1 , pp. 13-20
    • Salanti, G.1    Sanderson, S.2    Higgins, J.P.3
  • 18
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W, (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22: 719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 19
    • 39549093107 scopus 로고    scopus 로고
    • Recent developments in meta-analysis
    • Sutton AJ, Higgins JP, (2008) Recent developments in meta-analysis. Stat Med 27 (5): 625-650.
    • (2008) Stat Med , vol.27 , Issue.5 , pp. 625-650
    • Sutton, A.J.1    Higgins, J.P.2
  • 20
    • 0037098178 scopus 로고    scopus 로고
    • How should meta-regression analyses be undertaken and interpreted?
    • Thompson SG, Higgins JP, (2002) How should meta-regression analyses be undertaken and interpreted? Stat Med 21 (11): 1559-1573.
    • (2002) Stat Med , vol.21 , Issue.11 , pp. 1559-1573
    • Thompson, S.G.1    Higgins, J.P.2
  • 21
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Baigent C, Keech A, Kearney PM, Blackwell L, et al. (2005) Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366 (9493): 1267-1278.
    • (2005) Lancet , vol.366 , Issue.9493 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3    Blackwell, L.4
  • 22
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
    • Cholesterol Treatment Trialists' (CTT) Collaboration
    • Baigent C, Blackwell L, Emberson J, Holland LE, et al. Cholesterol Treatment Trialists' (CTT) Collaboration (2010) Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 376 (9753): 1670-1681.
    • (2010) Lancet , vol.376 , Issue.9753 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3    Holland, L.E.4
  • 23
    • 0037464808 scopus 로고    scopus 로고
    • Interaction revisited: the difference between two estimates
    • Altman DG, Bland JM, (2003) Interaction revisited: the difference between two estimates. BMJ 326 (7382): 219.
    • (2003) BMJ , vol.326 , Issue.7382 , pp. 219
    • Altman, D.G.1    Bland, J.M.2
  • 24
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG, (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21 (11): 1539-1558.
    • (2002) Stat Med , vol.21 , Issue.11 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 25
    • 83755205105 scopus 로고    scopus 로고
    • The Trp719arg Variant of KIF6 and Cardiovascular Outcomes in Statin-Treated, Coronary Stable Patients of the TNT and IDEAL Prospective Studies
    • Arsenault B, Boekholdt SM, Hovingh GC, Hyde CL, DeMicco DA, et al. (2011) The Trp719arg Variant of KIF6 and Cardiovascular Outcomes in Statin-Treated, Coronary Stable Patients of the TNT and IDEAL Prospective Studies. J Am Coll Cardiol 57: 1203.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 1203
    • Arsenault, B.1    Boekholdt, S.M.2    Hovingh, G.C.3    Hyde, C.L.4    DeMicco, D.A.5
  • 26
    • 64049119620 scopus 로고    scopus 로고
    • Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study
    • Stewart AF, Dandona S, Chen L, Assogba O, Belanger M, et al. (2009) Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study. J Am Coll Cardiol 53 (16): 1471-1472.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.16 , pp. 1471-1472
    • Stewart, A.F.1    Dandona, S.2    Chen, L.3    Assogba, O.4    Belanger, M.5
  • 28
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, et al. (2007) A common allele on chromosome 9 associated with coronary heart disease. Science 316: 1488-1491.
    • (2007) Science , vol.316 , pp. 1488-1491
    • McPherson, R.1    Pertsemlidis, A.2    Kavaslar, N.3    Stewart, A.4    Roberts, R.5
  • 29
  • 30
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 31
    • 70749096913 scopus 로고    scopus 로고
    • Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
    • Myocardial Infarction Genetics Consortium
    • Kathiresan S, Voight BF, Purcell S, Musunuru K, et al. Myocardial Infarction Genetics Consortium (2009) Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 41: 334-341.
    • (2009) Nat Genet , vol.41 , pp. 334-341
    • Kathiresan, S.1    Voight, B.F.2    Purcell, S.3    Musunuru, K.4
  • 32
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
    • Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, et al. (2004) Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 364: 937-952.
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Dans, T.4    Avezum, A.5
  • 35
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, et al. (2011) Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 43 (4): 333-338.
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 333-338
    • Schunkert, H.1    König, I.R.2    Kathiresan, S.3    Reilly, M.P.4    Assimes, T.L.5


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