The potential protective effect of physalis peruviana L. against carbon tetrachloride-induced hepatotoxicity in rats is mediated by suppression of oxidative stress and downregulation of MMP-9 expression

Oxidative Medicine and Cellular Longevity

Volumn 2014, Issue , 2014, Pages

  Al Olayan, Ebtisam M ^a   El Khadragy, Manal F ^a,b   Aref, Ahmed M ^c   Othman, Mohamed S ^d   Kassab, Rami B ^b,e   Abdel Moneim, Ahmed E ^b,f  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Helwan University   (Egypt)

^c 6th October City   (Egypt)

^d October University for Modern Sciences and Art   (Egypt)

^e MASARYK UNIVERSITY   (Czech Republic)

^f UNIVERSITY OF OVIEDO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; FLAVONOIDS; NITRIC OXIDE; OXYGEN; PEPTIDES; PLANTS (BOTANY); RESTORATION;

ACTIVE CONSTITUENTS; GLUTATHIONE CONTENTS; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE-S-TRANSFERASE; HEPATOPROTECTIVE EFFECTS; PROTECTIVE EFFECTS; SUPER OXIDE DISMUTASE;

RATS;

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CATALASE; GELATINASE B; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NITRIC OXIDE; PHYSALIS PERUVIANA EXTRACT; PLANT EXTRACT; QUERCETIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; OXIDOREDUCTASE; PROTECTIVE AGENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME REPRESSION; FRUIT JUICE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIPID PEROXIDATION; LIVER FUNCTION TEST; LIVER HOMOGENATE; LIVER PROTECTION; MALE; MASS FRAGMENTOGRAPHY; MEDICINAL PLANT; NONHUMAN; OXIDATIVE STRESS; PHYSALIS PERUVIANA; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; BLOOD; CHEMISTRY; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; LIVER; METABOLISM; PATHOLOGY; PHYSALIS; TOXICITY; WISTAR RAT;

ANIMALS; CARBON TETRACHLORIDE; DOWN-REGULATION; DRUG-INDUCED LIVER INJURY; LIVER; LIVER FUNCTION TESTS; MALE; MALONDIALDEHYDE; MATRIX METALLOPROTEINASE 9; NITRIC OXIDE; OXIDATIVE STRESS; OXIDOREDUCTASES; PHYSALIS; PLANT EXTRACTS; PROTECTIVE AGENTS; RATS; RATS, WISTAR;

EID: 84901249460     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/381413     Document Type: Article

References (53)

1. Tacke F., Luedde T., Trautwein C., Inflammatory pathways in liver homeostasis and liver injury. Clinical Reviews in Allergy and Immunology 2009 36 1 4 12 2-s2.0-61949261267 10.1007/s12016-008-8091-0
2. Vitaglione P., Morisco F., Caporaso N., Fogliano V., Dietary antioxidant compounds and liver health. Critical Reviews in Food Science and Nutrition 2004 44 7-8 575 586 2-s2.0-17444419030 10.1080/10408690490911701 (Pubitemid 40536485)
3. Hsu Y.-W., Tsai C.-F., Chang W.-H., Ho Y.-C., Chen W.-K., Lu F.-J., Protective effects of Dunaliella salina-a carotenoids-rich alga, against carbon tetrachloride-induced hepatotoxicity in mice. Food and Chemical Toxicology 2008 46 10 3311 3317 2-s2.0-52949113803 10.1016/j.fct.2008.07.027
4. Pohl L. R., Schulick R. D., Highet R. J., George J. W., Reductive-oxygenation mechanism of metabolism of carbon tetrachloride to phosgene by cytochrome P-450. Molecular Pharmacology 1984 25 2 318 321 2-s2.0-0021345909 (Pubitemid 14173341)
5. Kurata M., Suzuki M., Agar N. S., Antioxidant systems and erythrocyte life-span in mammals. Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology 1993 106 3 477 487 2-s2.0-0027373905 10.1016/0305-0491(93) 90121-K (Pubitemid 23310844)
6. Ghatak S., Biswas A., Dhali G. K., Chowdhury A., Boyer J. L., Santra A., Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice. Toxicology and Applied Pharmacology 2011 251 1 59 69 2-s2.0-78751638450 10.1016/j.taap.2010.11.016
7. Fu Y., Zheng S., Lin J., Ryerse J., Chen A., Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation. Molecular Pharmacology 2008 73 2 399 409 2-s2.0-38549153486 10.1124/mol.107.039818 (Pubitemid 351159210)
8. Deng G., Wang J., Zhang Q., He H., Wu F., Feng T., Zhou J., Zou K., Hattori M., Hepatoprotective effects of phloridzin on hepatic fibrosis induced by carbon tetrachloride against oxidative stress-triggered damage and fibrosis in rats. Biological & Pharmaceutical Bulletin 2012 35 7 1118 1125 10.1248/bpb.b12-00057
9. Othman M. S., Nada A., Zaki H. S., Abdel Moneim A. E., Effect of Physalis peruviana L. on cadmium-induced testicular toxicity in rats. Biological Trace Element Research, 2014 10.1007/s12011-014-9955-1
10. Othman M. S., Safwat G., Aboulkhair M., Abdel Moneim A. E., The Potential Effect of Berberine in Mercury-induced Hepatorenal Toxicity in Albino Rats. Food and Chemical Toxicology, 2014 10.1016/j.fct.2014.04.012
11. Fang S.-T., Liu J.-K., Li B., Ten new withanolides from Physalis peruviana. Steroids 2012 77 1-2 36 44 2-s2.0-83655201231 10.1016/j.steroids. 2011.09.011
12. Wang I.-K., Lin-Shiau S.-Y., Lin J.-K., Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. European Journal of Cancer 1999 35 10 1517 1525 2-s2.0-0032856994 10.1016/S0959-8049(99)00168-9 (Pubitemid 29454650)
13. Nishikimi M., Appaji Rao N., Yagi K., The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochemical and Biophysical Research Communications 1972 46 2 849 854 2-s2.0-0015530358
14. Abdel Moneim A. E., The neuroprotective effects of purslane (Portulaca oleracea) on rotenone-induced biochemical changes and apoptosis in brain of rat. CNS Neurological Disorders Drug Targets 2013 12 6 830 841
15. Sohn D. H., Yun Y.-P., Park K. S., Veech R. L., Song B. J., Post-translational reduction of cytochrome P450IIE by CCl4, its substrate. Biochemical and Biophysical Research Communications 1991 179 1 449 454 2-s2.0-0026001381
16. Reitman S., Frankel S., A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. American journal of clinical pathology 1957 28 1 56 63 2-s2.0-66349129125
17. Szasz G., A kinetic photometric method for serum gamma-glutamyl transpeptidase. Clinical Chemistry 1969 15 2 124 136 2-s2.0-0014467815
18. Belfield A., Goldberg D. M., Revised assay for serum phenyl phosphatase activity using 4-amino-antipyrine. Enzyme 1971 12 5 561 573 2-s2.0-0015195627
19. Garber C. C., Jendrassik-Grof analysis for total and direct bilirubin in serum with a centrifugal analyzer. Clinical Chemistry 1981 27 1410 1416 (Pubitemid 11041581)
20. Ohkawa H., Ohishi N., Yagi K., Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 1979 95 2 351 358 2-s2.0-0018384650 (Pubitemid 9194347)
21. Green L. C., Wagner D. A., Glogowski J., Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Analytical Biochemistry 1982 126 1 131 138 2-s2.0-0020448709 (Pubitemid 13203451)
22. Ellman G. L., Tissue sulfhydryl groups. Archives of Biochemistry and Biophysics 1959 82 1 70 77 2-s2.0-3042934967
23. Aebi H., Catalase in vitro. Methods in Enzymology 1984 105 121 126 2-s2.0-0021318441 10.1016/S0076-6879(84)05016-3
24. Paglia D. E., Valentine W. N., Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. The Journal of Laboratory and Clinical Medicine 1967 70 1 158 169 2-s2.0-0014108436
25. Habig W. H., Pabst M. J., Jakoby W. B., Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. The Journal of Biological Chemistry 1974 249 22 7130 7139 2-s2.0-0016275313
26. Factor V. M., Kiss A., Woitach J. T., Wirth P. J., Thorgeirsson S. S., Disruption of redox homeostasis in the transforming growth factor- α /c- myc transgenic mouse model of accelerated hepatocarcinogenesis. The Journal of Biological Chemistry 1998 273 25 15846 15853 2-s2.0-0032546792 10.1074/jbc.273.25.15846 (Pubitemid 28298207)
27. Abdel Moneim A. E., El-Deib K. M., The Possible protective effects of Physalis peruviana on carbon tetrachloride-induced nephrotoxicity in male albino rats. Life Science Journal 2012 9 3 1038 1052
28. Yun J.-W., Kim C.-W., Bae I.-H., Park Y.-H., Chung J.-H., Lim K.-M., Kang K.-S., Determination of the key innate genes related to individual variation in carbon tetrachloride-induced hepatotoxicity using a pre-biopsy procedure. Toxicology and Applied Pharmacology 2009 239 1 55 63 2-s2.0-67650684954 10.1016/j.taap.2009.05.018
29. Adesanoye O. A., Farombi E. O., Hepatoprotective effects of Vernonia amygdalina (astereaceae) in rats treated with carbon tetrachloride. Experimental and Toxicologic Pathology 2010 62 2 197 206 2-s2.0-75949103368 10.1016/j.etp.2009.05.008
30. Coballase-Urrutia E., Pedraza-Chaverri J., Cárdenas- Rodríguez N., Huerta-Gertrudis B., García-Cruz M. E., Ramírez-Morales A., Sánchez-González D. J., Martínez-Martínez M. C., Camacho-Carranza R., Espinosa-Aguirre J., Hepatoprotective effect of acetonic and methanolic extracts of Heterotheca inuloides against CCl4-induced toxicity in rats. Experimental and Toxicologic Pathology 2011 63 4 363 370 2-s2.0-79953756571 10.1016/j.etp.2010.02.012
31. Boll M., Weber L. W. D., Becker E., Stampfl A., Mechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites. Zeitschrift fur Naturforschung C: Journal of Biosciences 2001 56 7-8 649 659 2-s2.0-0034892847 (Pubitemid 32745296)
32. Ganie S. A., Zargar B. A., Masood A., Zargar M. A., Hepatoprotective and antioxidant activity of rhizome of Podophyllum hexandrum against carbon tetra chloride induced hepatotoxicity in rats. Biomedical and Environmental Sciences 2013 26 3 209 221
33. Breikaa R. M., Algandaby M. M., El-Demerdash E., Abdel-Naim A. B., Multimechanistic antifibrotic effect of biochanin a in rats: implications of proinflammatory and profibrogenic mediators. PLoS ONE 2013 8 7 e69276 10.1371/journal.pone.0069276
34. Ramadan M. F., Bioactive phytochemicals, nutritional value, and functional properties of cape gooseberry (Physalis peruviana): an overview. Food Research International 2011 44 7 1830 1836 2-s2.0-79959993835 10.1016/j.foodres.2010.12.042
35. Chang J. C., Lin C. C., Wu S. J., Lin D. L., Wang S. S., Miaw C. L., Ng L. T., Antioxidative and hepatoprotective effects of Physalis peruviana extract against acetaminophen-induced liver injury in rats. Pharmaceutical Biology 2008 46 10-11 724 731 2-s2.0-57649216327 10.1080/13880200802215768
36. Arun M., Asha V. V., Preliminary studies on antihepatotoxic effect of Physalis peruviana Linn. (Solanaceae) against carbon tetrachloride induced acute liver injury in rats. Journal of Ethnopharmacology 2007 111 1 110 114 2-s2.0-33947601949 10.1016/j.jep.2006.10.038 (Pubitemid 46482883)
37. El-Gengaihi S. E., Hassan E. E., Hamed M. A., Zahran H. G., Mohammed M. A., Chemical composition and biological evaluation of Physalis peruviana root as hepato-renal protective agent. Journal of Dietary Supplements 2013 10 1 39 53 10.3109/19390211.2012.760509
38. Wu S.-J., Ng L.-T., Lin D.-L., Huang S.-N., Wang S.-S., Lin C.-C., Physalis peruviana extract induces apoptosis in human Hep G2 cells through CD95/CD95L system and the mitochondrial signaling transduction pathway. Cancer Letters 2004 215 2 199 208 2-s2.0-5644298419 10.1016/j.canlet.2004.05.001 (Pubitemid 39370038)
39. Wu S. J., Tsai J. Y., Chang S. P., Lin D. L., Wang S. S., Huang S. N., Ng L. T., Supercritical carbon dioxide extract exhibits enhanced antioxidant and anti-inflammatory activities of Physalis peruviana. Journal of Ethnopharmacology 2006 108 3 407 413 2-s2.0-33750604833 10.1016/j.jep.2006.05.027 (Pubitemid 44693106)
40. Mandal A. K., Das N., Sugar coated liposomal flavonoid: a unique formulation in combating carbontetrachloride induced hepatic oxidative damage. Journal of Drug Targeting 2005 13 5 305 315 2-s2.0-24644504005 10.1080/10611860500230278 (Pubitemid 41283164)
41. Janbaz K. H., Saeed S. A., Gilani A. H., Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine 2004 11 5 424 430 2-s2.0-3242748962 10.1016/j.phymed. 2003.05.002 (Pubitemid 38980523)
42. Tatiya A. U., Surana S. J., Sutar M. P., Gamit N. H., Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats. Pharmacognosy Research 2012 4 1 50 56
43. Kim J., Chehade J., Pinnas J. L., Mooradian A. D., Effect of select antioxidants on malondialdehyde modification of proteins. Nutrition 2000 16 11-12 1079 1081 2-s2.0-0033676092 10.1016/S0899-9007(00)00446-9
44. Leung T.-M., Fung M.-L., Liong E. C., Lau T. Y. H., Nanji A. A., Tipoe G. L., Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice. Histology and Histopathology 2011 26 2 201 211 2-s2.0-78651305270
45. Zhu W., Fung P. C. W., The roles played by crucial free radicals like lipid free radicals, nitric oxide, and enzymes NOS and NADPH in CCl4-induced acute liver injury of mice. Free Radical Biology and Medicine 2000 29 9 870 880 2-s2.0-0034333125 10.1016/S0891-5849(00)00396-8
46. El-Gengaihi S. E., Hamed M. A., Khalaf-Allah R., Mohammed M. A., Golden berry juice attenuates the severity of hepatorenal injury. Journal of Dietary Supplements 2013 10 4 357 369
47. Halliwell B., Gutteridge J. M. C., Cellular responses to oxidative stress: adaptation, damage, repair, senescence and death. Free Radicals in Biology and Medicine 2007 Oxford, UK Oxford University Press 187 267
48. Valko M., Leibfritz D., Moncol J., Cronin M. T. D., Mazur M., Telser J., Free radicals and antioxidants in normal physiological functions and human disease. International Journal of Biochemistry and Cell Biology 2007 39 1 44 84 2-s2.0-33749986298 10.1016/j.biocel.2006.07.001 (Pubitemid 44566469)
49. Vassiliadis E., Larsen D. V., Clausen R. E., Veidal S. S., Barascuk N., Larsen L., Simonsen H., Silvestre T. S., Hansen C., Overgaard T., Leeming D. J., Karsdal M. A., Measurement of co3-610, a potential liver biomarker derived from matrix metalloproteinase-9 degradation of collagen type iii, in a rat model of reversible carbon-tetrachloride-induced fibrosis. Biomarker Insights 2011 6 49 58 2-s2.0-79958242395 10.4137/BMI.S6347
50. Kahraman A., Bronk S. F., Cazanave S., Werneburg N. W., Mott J. L., Contreras P. C., Gores G. J., Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse. Hepatology Research 2009 39 8 805 813 2-s2.0-68349128422 10.1111/j.1872-034X.2009.00541.x
51. Hollman P. C. H., Van Trijp J. M. P., Mengelers M. J. B., De Vries J. H. M., Katan M. B., Bioavailability of the dietary antioxidant flavonol quercetin in man. Cancer Letters 1997 114 1-2 139 140 2-s2.0-0030891773 10.1016/S0304-3835(97)04644-2 (Pubitemid 27140094)
52. Boots A. W., Wilms L. C., Swennen E. L. R., Kleinjans J. C. S., Bast A., Haenen G. R. M. M., In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition 2008 24 7-8 703 710 2-s2.0-44649099599 10.1016/j.nut.2008.03.023 (Pubitemid 351783378)
53. Tatsimo S. J. N., Tamokou J. D. D. D., Havyarimana L., Csupor D., Forgo P., Judit H., Kuiate J. R., Pierre T., Antimicrobial and antioxidant activity of kaempferol rhamnoside derivatives from Bryophyllum pinnatum. BMC Research Notes 2012 5 158 2-s2.0-84858415983 10.1186/1756-0500-5-158