Protective effects of Dunaliella salina - A carotenoids-rich alga, against carbon tetrachloride-induced hepatotoxicity in mice

Food and Chemical Toxicology

Volumn 46, Issue 10, 2008, Pages 3311-3317

  Hsu, Yu Wen ^a   Tsai, Chia Fang ^a   Chang, Wen Huei ^a   Ho, Yung Chyuan ^a   Chen, Wen Kang ^b   Lu, Fung Jou ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAINAN INSTITUTE OF NURSING   (Taiwan)

Author keywords

Carbon tetrachloride; Dunaliella salina; Hepatoprotective effects

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CAROTENOID; CATALASE; DUNALIELLA SALINA EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; PLANT EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN;

ALGAE; ANIMALS; CARBON TETRACHLORIDE POISONING; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATITIS, TOXIC; LIPID PEROXIDATION; LIVER; MALE; MICE; MICE, INBRED ICR; OXIDOREDUCTASES; PLANTS, MEDICINAL;

ALGAE; DUNALIELLA SALINA; MUS;

EID: 52949113803     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.07.027     Document Type: Article

References (46)

1. Aharon O. A hundred years of Dunaliella research: 1905-2005. Saline Syst. 1 (2005) 1-14
2. Aruoma O.I. Nutrition and health aspects of free radicals and antioxidants. Food Chem. Toxicol. 32 (1994) 671-683
3. Baudrimont I., Ahouandjivo R., and Creppy E.E. Prevention of lipid peroxidation induced by ochratoxin A in Vero cells in culture by several agents. Chem. Biol. Interact. 104 (1997) 29-40
4. Bansal A.K., Bansal M., Soni G., and Bhatnagar D. N-nitrosodiethylamine induced oxidative stress in rat liver. Chem. Biol. Interact. 156 (2005) 101-111
5. Berton T.R., Conti C.J., Mitchell D.L., Aldaz C.M., Lubet R.A., and Fischer S.M. The effect of vitamin E acetate on ultraviolet induced mouse skin carcinogenesis. Mol. Carcinog. 23 (1998) 175-184
6. Biswas S.J., Bhattacharjee N., and Khuda-Bukhsh A.R. Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice. Food Chem. Toxicol. 46 (2008) 1474-1487
7. Bitterman N., Melamed Y., and Ben-Amotz A. β-Carotene and CNS oxygen toxicity in rats. J. Appl. Physiol. 76 (1994) 1073-1076
8. Borowitzka M.A. Micro-algae as sources of fine chemicals. Microbiol. Sci. 3 (1986) 372-375
9. Brattin W.J., Glende Jr. E.A., and Recknagel R.O. Pathological mechanisms in carbon tetrachloride hepatotoxicity. J. Free Radic. Biol. Med. 1 (1985) 27-38
10. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. In: Fleischer S., and Packer L. (Eds). Methods in Enzymology vol. 52 (1978), Academic Press, New York, San Francisco, London 302-310
11. Burton K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimeteric estimation of deoxyribonucleic acid. Biochem. J. 62 (1956) 315
12. Cantin A.M., White T.B., Cross C.E., Forman H.J., Sokol R.J., and Borowitz D. Antioxidants in cystic fibrosis Conclusions from the CF Antioxidant Workshop, Bethesda, MD, November 11-12, 2003. J. Free Radic. Biol. Med. 42 (2007) 15-31
13. Castor J.A., Ferrya G.C., Castro C.R., Sasame S., Fenes O.M., and Gilette J.R. Prevention of carbon tetrachloride-induced necrosis by inhibitors of drug metabolism. Further studies on the mechanism of their action. Biochem. Pharmacol. 23 (1974) 295-302
14. Chidambara Murthy K.N., Vanitha A., Mahadeva Swamy M., and Ravishankar G.A. Antioxidant and antimicrobial activity of Cissus quadrangularis L. J. Med. Food 06 (2003) 99-105
15. Chidambara Murthy K.N., Rajesha J., Vanitha A., Mahadeva Swamy M., and Ravishankar G.A. Protective effect of Dunaliella salina - a marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats. Hepatol. Res. 33 (2005) 313-319
16. 4-induced hepatotoxicity in mice. Food Chem. Toxicol. 45 (2007) 456-464
17. Edge R., McGarvey D.J., and Truscott T.G. The carotenoids as antioxidants - a review. J. Photochem. Photobiol. B, Biol. 41 (1997) 189-200
18. Finney K.F., Pomeranz Y., and Bruinsma B.L. Use of algae Dunaliella as a protein supplement in bread. Cereal Chem. 61 (1984) 402-406
19. Fujii Y., Ben-Amotz A., Sakamoto S., and Nagasawa H. Effects of β-carotene rich algae Dunaliella bardawil on the dynamic changes of normal and neoplastic mammary cells and general metabolism in mice. Anticancer Res. 13 (1993) 389-393
20. Halliwell B. Antioxidants and human disease: a general introduction. Nutr. Rev. 55 (1997) 44-52
21. Halliwell B., and Gutteridge J.M.C. Role of free radicals and catalytic metal irons in human disease: an overview. Meth. Enzymol. 186 (1990) 59-85
22. Hattori T., Ito M., and Suzuki Y. Studies on antinephritic effects of plant components in rats (1). Effects of saikosaponins original type anti-GBM nephritis in rats and its mechanisms. Nippon Yakurigaku Zasshi 97 (1991) 13-21
23. Hu C.C., Lin J.T., Lu F.J., Chou F.P., and Yang D.J. Determination of carotenoids in Dunaliella salina cultivated in Taiwan and antioxidant capacity of the algal carotenoid extract. Food Chem. 109 (2008) 439-446
24. 4 poisoning?. J. Free Rad. Biol. Med. 28 (2000) 838-845
25. Krinsky N.I. Antioxidant functions of carotenoids. J. Free Rad. Biol. Med. 7 (1989) 617-635
26. Krinsky N.I., and Deneke S.M. Interaction of oxygen and oxyradicals with carotenoids. J.N.C.L 69 (1982) 205-209
27. Lee K.J., Choi J.H., and Jeong H.G. Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice. Food Chem. Toxicol. 45 (2007) 2118-2125
28. Levin G., and Mokady S. Antioxidant activity of 9-cis compared to all-trans β-carotene in vitro. J. Free Radical Biol. Med. 17 (1994) 77-82
29. 4-induced hepatotoxicity in mice. Food Chem. Toxicol. 45 (2007) 456-464
30. Loguercio C., and Federico A. Oxidative stress in viral and alcoholic hepatitis. J. Free Radic. Biol. Med. 34 (2003) 1-10
31. Mokady S., Abramovici A., and Cogau U. The safety evaluation of Dunaliella bardawil as a potential food supplement. Food Chem. Toxicol. 4 (1989) 221-226
32. Naik S.R. Antioxidants and their role in biological functions: an overview. Indian Drugs 40 (2003) 501-516
33. Naik S.R., and Panda V.S. Antioxidant and hepatoprotective effects of Ginkgo biloba phytosomes in carbon tetrachloride-induced liver injury in rodents. Liver Int. 27 (2007) 393-399
34. Recknagel R.O. Carbon tetrachloride hepatotoxicity. Pharmacol. Rev. 19 (1967) 145-208
35. Recknagel R.O., Glende Jr. E.A., Dolak J.A., and Waller R.L. Mechanisms of carbon tetrachloride toxicity. Pharmacol. Ther. 43 (1989) 139-154
36. Reiter R.J., Tan D., Osuna C., and Gitto E. Actions of melatonin in the reduction of oxidative stress. J. Biomed. Sci. 7 (2000) 444-458
37. Rudnicki M., Silveira M.M., Pereira T.V., Oliveira M.R., Reginatto F.H., Dal-Pizzol F., and Moreira J.C.F. Protective effects of Passiflora alata extract pretreatment on carbon tetrachloride induced oxidative damage in rats. Food Chem. Toxicol. 45 (2007) 656-661
38. Slater T.F., and Sawyer B.C. The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents. Biochem. J. 123 (1971) 823-828
39. Sodergren E., Cederberg J., Vessby B., and Basu S. Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats. Eur. J. Nutr. 40 (2001) 10-16
40. Taira Z., Yabe K., Hamaguchi Y., Hirayama K., Kishimoto M., Ishida S., and Ueda Y. Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats. Food Chem. Toxicol. 42 (2004) 803-807
41. Vaca C.E., Wilhelm J., and Harms-Rihsdahl M. Interaction of lipid peroxidation product with DNA. A Rev. Mutat. Res. Rev. Genet. Toxicol. 195 (1988) 137-149
42. Vitaglione P., Morisco F., Caporaso N., and Fogliano V. Dietary antioxidant compounds and liver health. Crit. Rev. Food Sci. Nutr. 44 (2004) 575-586
43. 4 -induced liver damage. Food Chem. Toxicol. 42 (2004) 609-617
44. Werman M.J., Ben-Amotz A., and Mokady S. Availability and antiperoxidative effects of β-carotene from Dunaliella bardawil in alcohol-drinking rats. J. Nutr. Biochem. 10 (1999) 449-454
45. Wu J., Danielsson A., and Zern MA. Toxicity of hepatotoxins: new insights into mechanisms and therapy. Expert Opin. Investig. Drugs 8 (1999) 585-607
46. ® on carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats. Food Chem. Toxicol. 46 (2008) 380-387