Development and preclinical evaluation of new 124I-folate conjugates for PET imaging of folate receptor-positive tumors

Nuclear Medicine and Biology

Volumn 41, Issue 6, 2014, Pages 457-463

  AlJammaz, I ^a   Al Otaibi, B ^a   Al Rumayan, F ^a   Al Yanbawi, S ^a   Amer, S ^a   Okarvi, S M ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Folate receptor; Ovarian cancer; PET radiopharmaceuticals

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; FOLATE RECEPTOR; FOLIC ACID; IODOBENZOIC ACID DERIVATIVE; N SUCCINIMIDYL 3 IODOBENZOATE; N SUCCINIMIDYL 3 IODOBENZOATE FOLATE CONJUGATE IODINE 124; N SUCCINIMIDYL 3 IODOPYRIDINECARBOXYLATE; N SUCCINIMIDYL 3 IODOPYRIDINECARBOXYLATE FOLATE CONJUGATE IODINE 124; TRACER; UNCLASSIFIED DRUG; FOLATE TRANSPORTER; IODOBENZENE; PYRIDINE; PYRIDINE DERIVATIVE; RADIOACTIVE IODINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CANCER DIAGNOSIS; CANCER STAGING; CHEMICAL REACTION; CONTROLLED STUDY; DRUG DEVELOPMENT; DRUG DISTRIBUTION; DRUG PURIFICATION; DRUG PURITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; FOLATE RECEPTOR POSITIVE CANCER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; KB CELL LINE; METASTASIS; MOLECULAR PROBE; MOUSE; NEOPLASM; NONHUMAN; NUDE MOUSE; OVARY CANCER; PLASMA CLEARANCE; POSITRON EMISSION TOMOGRAPHY; TREATMENT RESPONSE; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; DIAGNOSTIC USE; DRUG STABILITY; METABOLISM; PROCEDURES; RADIOCHEMISTRY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; DRUG STABILITY; FOLIC ACID; FOLIC ACID TRANSPORTERS; HUMANS; IODINE RADIOISOTOPES; IODOBENZENES; KB CELLS; MICE; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RADIOCHEMISTRY;

EID: 84901248961     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2014.03.013     Document Type: Article

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