Novel synthesis and preclinical evaluation of folic acid derivatives labeled with 18F-[FDG] for PET imaging of folate receptor-positive tumors

Nuclear Medicine and Biology

Volumn 39, Issue 6, 2012, Pages 864-870

  Al Jammaz, I ^a   Al Otaibi, B ^a   Amer, S ^a   Al Hokbany, N ^a   Okarvi, S ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

18F fluorination; 18F fluorofolate; 18F fluoromethotrexate; 18F FDG; Ovarian cancer

Indexed keywords

FLUORODEOXYGLUCOSE F 18; FLUORODEOXYGLUCOSE FOLATE F 18; FLUORODEOXYGLUCOSE METHOTREXATE F 18; FOLATE RECEPTOR; FOLIC ACID; FOLIC ACID DERIVATIVE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOMATION; BAGG ALBINO MOUSE; CANCER DIAGNOSIS; CANCER STAGING; CELL FRACTIONATION; CELL LINE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG MONITORING; DRUG POTENCY; DRUG PURIFICATION; DRUG PURITY; DRUG RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; FLUORINATION; HEPATOBILIARY SYSTEM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; KB CELL LINE; METASTASIS; MOLECULAR PROBE; MOUSE; NONHUMAN; NUDE MOUSE; OVARY CANCER; PLASMA CLEARANCE; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; TUMOR DIAGNOSIS; TUMOR XENOGRAFT; URINARY TRACT;

ANIMALS; BIOLOGICAL TRANSPORT; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG STABILITY; FEMALE; FLUORODEOXYGLUCOSE F18; FOLIC ACID; FOLIC ACID TRANSPORTERS; HUMANS; ISOTOPE LABELING; KB CELLS; METHOTREXATE; MICE; MOUTH NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY;

EID: 84863990889     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2012.02.005     Document Type: Article

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