Cytotoxic activity of hirsutanone, a diarylheptanoid isolated from Alnus glutinosa leaves

Phytomedicine

Volumn 21, Issue 6, 2014, Pages 866-870

  Leon Gonzalez A J ^a   Acero, N ^b   Munoz Mingarro D ^b   Lopez Lazaro M ^a   Martin Cordero C ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b UNIVERSIDAD SAN PABLO CEU   (Spain)

Author keywords

Alnus glutinosa; Cytotoxicity; Diarylheptanoid; Hirsutanone; Reactive oxygen species; Topoisomerase II

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTINEOPLASTIC AGENT; ANTIOXIDANT; DNA TOPOISOMERASE (ATP HYDROLYSING); HEPTANE DERIVATIVE; HIRSUTANONE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; DNA; PLANT EXTRACT;

ALDER; ALNUS GLUTINOSA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL LINE; CELL DEATH; CELL VIABILITY; COLORIMETRY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DNA CLEAVAGE; DOUBLE STRANDED DNA BREAK; DRUG ISOLATION; DRUG MECHANISM; HELA CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; MTT ASSAY; PLANT LEAF; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN STABILITY; ADENOCARCINOMA; CHEMISTRY; COLONIC NEOPLASMS; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; PHYTOTHERAPY;

ALNUS GLUTINOSA; BETULACEAE;

ADENOCARCINOMA; ALNUS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DEATH; COLONIC NEOPLASMS; DIARYLHEPTANOIDS; DNA; DNA TOPOISOMERASES, TYPE II; HT29 CELLS; HUMANS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; REACTIVE OXYGEN SPECIES;

EID: 84901239132     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.01.008     Document Type: Article

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