Loss-of-function of the voltage-gated sodium channel NaV1.5 (Channelopathies) in patients with irritable bowel syndrome

Gastroenterology

Volumn 146, Issue 7, 2014, Pages 1659-1668

  Beyder, Arthur ^a   Mazzone, Amelia ^a   Strege, Peter R ^a   Tester, David J ^b   Saito, Yuri A ^a   Bernard, Cheryl E ^a   Enders, Felicity T ^b   Ek, Weronica E ^c   Schmidt, Peter T ^c   Dlugosz, Aldona ^c   Lindberg, Greger ^c   Karling, Pontus ^d   Ohlsson, Bodil ^e   Gazouli, Maria ^f   Nardone, Gerardo ^g   Cuomo, Rosario ^h   Usai Satta, Paolo ⁱ   Galeazzi, Francesca ^j   Neri, Matteo ^k   Portincasa, Piero ^l   Bellini, Massimo ^m   Barbara, Giovanni ⁿ   Camilleri, Michael ^a   Locke III, G Richard ^a   Talley, Nicholas J ^a   D'Amato, Mauro ^c   Ackerman, Michael J ^b   Farrugia, Gianrico ^a   more..

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d UMEÅ UNIVERSITY   (Sweden)

^e LUND UNIVERSITY HOSPITAL   (Sweden)

^f UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^g UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^h FEDERICO II UNIVERSITY HOSPITAL   (Italy)

ⁱ BROTZU HOSPITAL   (Italy)

^j UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^k UNIVERSITY OF CHIETI   (Italy)

^l UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^m UNIVERSITY OF PISA   (Italy)

ⁿ UNIVERSITY OF BOLOGNA   (Italy)

more..

Author keywords

Genetics; GI Motility; Polymorphism; Voltage Gated Sodium Channel

Indexed keywords

MEXILETINE; SODIUM CHANNEL NAV1.5;

ABDOMINAL PAIN; ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; ATAXIA; BLOATING; BRUGADA SYNDROME; CARBOXY TERMINAL SEQUENCE; CONSTIPATION; CONTROLLED STUDY; DIARRHEA; DIZZINESS; ELECTROCARDIOGRAM; ELECTROPHYSIOLOGY; FEMALE; FOLLOW UP; GAIN OF FUNCTION MUTATION; GASTROINTESTINAL TRANSIT; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IRRITABLE COLON; LONG QT SYNDROME 3; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NAUSEA; PRIORITY JOURNAL; SICK SINUS SYNDROME; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS; SODIUM CHANNEL NAV1.5 GENE; SODIUM CURRENT; SODIUM TRANSPORT; STOMACH EMPTYING; SUDDEN DEATH; SUDDEN INFANT DEATH SYNDROME; TELEMETRY; VOLTAGE CLAMP TECHNIQUE; WILD TYPE;

GENETICS; GI MOTILITY; POLYMORPHISM; VOLTAGE-GATED SODIUM CHANNEL;

ADOLESCENT; ADULT; AGED; CASE-CONTROL STUDIES; CHANNELOPATHIES; CONSTIPATION; DIARRHEA; DNA MUTATIONAL ANALYSIS; FEMALE; GASTROINTESTINAL MOTILITY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HEK293 CELLS; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; MEMBRANE POTENTIALS; MIDDLE AGED; MUTATION, MISSENSE; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PHENOTYPE; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; TRANSFECTION; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS; YOUNG ADULT;

EID: 84901230979     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.02.054     Document Type: Article

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