Differences in the glucuronidation of resveratrol and pterostilbene: Altered enzyme specificity and potential gender differences

Drug Metabolism and Pharmacokinetics

Volumn 29, Issue 2, 2014, Pages 112-119

  Dellinger, Ryan W ^a,b   Garcia, Angela M Gomez ^a,b   Meyskens Jr , Frank L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gender; Glucuronidation; Pterostilbene; Resveratrol; UDP glucuronosyltransferase

Indexed keywords

GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A10; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A8; GLUCURONOSYLTRANSFERASE 1A9; HYDROXYL GROUP; POLYPHENOL; PTEROSTILBENE; RESVERATROL; STILBENE DERIVATIVE; SULFOTRANSFERASE; UNCLASSIFIED DRUG; GLUCURONIDE; ISOENZYME; UDP-GLUCURONOSYLTRANSFERASE, UGT1A3; UGT1A1 ENZYME;

ARTICLE; CANCER PREVENTION; CATALYSIS; DRUG ACTIVITY; DRUG BIOAVAILABILITY; ENZYME KINETICS; ENZYME SPECIFICITY; FEMALE; GLUCURONIDATION; HEALTH PROMOTION; HUMAN; LIVER MICROSOME; MALE; SEX DIFFERENCE; BIOTRANSFORMATION; COMPARATIVE STUDY; ENZYMOLOGY; KINETICS; LIVER; METABOLISM;

BIOTRANSFORMATION; FEMALE; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; ISOENZYMES; KINETICS; LIVER; MALE; MICROSOMES, LIVER; SEX FACTORS; STILBENES; SUBSTRATE SPECIFICITY;

EID: 84901230961     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-13-RG-012     Document Type: Article

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