-
1
-
-
33344458573
-
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
-
Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006; 4: 295-306.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 295-306
-
-
Miyakis, S.1
Lockshin, M.D.2
Atsumi, T.3
-
2
-
-
0026807033
-
Antiphospholipid antibody positive sera enhance endothelial cell procoagulant activity--studies in a thrombosis model
-
Oosting JD, Derksen RH, Blokzijl L, et al. Antiphospholipid antibody positive sera enhance endothelial cell procoagulant activity--studies in a thrombosis model. Thromb Haemost 1992; 68: 278-284.
-
(1992)
Thromb Haemost
, vol.68
, pp. 278-284
-
-
Oosting, J.D.1
Derksen, R.H.2
Blokzijl, L.3
-
3
-
-
0031886679
-
The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
-
Amengual O, Atsumi T, Khamashta MA, et al. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thromb Haemost 1998; 79: 276-281.
-
(1998)
Thromb Haemost
, vol.79
, pp. 276-281
-
-
Amengual, O.1
Atsumi, T.2
Khamashta, M.A.3
-
4
-
-
3242697048
-
Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep
-
Zhou H, Wolberg AS, Roubey RA. Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep. Blood 2004; 104: 2353-2358.
-
(2004)
Blood
, vol.104
, pp. 2353-2358
-
-
Zhou, H.1
Wolberg, A.S.2
Roubey, R.A.3
-
5
-
-
77953624768
-
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways
-
Lambrianides A, Carroll CJ, Pierangeli SS, et al. Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways. J Immunol 2010; 184: 6622-6628.
-
(2010)
J Immunol
, vol.184
, pp. 6622-6628
-
-
Lambrianides, A.1
Carroll, C.J.2
Pierangeli, S.S.3
-
6
-
-
0034917278
-
Tissue factor: An enzyme cofactor and a true receptor
-
Morrissey JH. Tissue factor: an enzyme cofactor and a true receptor. Thromb Haemost 2001; 86: 66-74.
-
(2001)
Thromb Haemost
, vol.86
, pp. 66-74
-
-
Morrissey, J.H.1
-
7
-
-
77956638726
-
Tissue factor and thrombosis: The clot starts here
-
Owens AP 3rd, Mackman N. Tissue factor and thrombosis: The clot starts here. Thromb Haemost 2010; 104: 432-439.
-
(2010)
Thromb Haemost
, vol.104
, pp. 432-439
-
-
Owens 3rd, A.P.1
MacKman, N.2
-
8
-
-
79959548657
-
Alternatively spliced Tissue Factor: Discovery, insights, clinical implications
-
Srinivasan R, Bogdanov VY. Alternatively spliced Tissue Factor: discovery, insights, clinical implications. Front Biosci 2011; 17: 3061-3071.
-
(2011)
Front Biosci
, vol.17
, pp. 3061-3071
-
-
Srinivasan, R.1
Bogdanov, V.Y.2
-
9
-
-
0034685886
-
High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II
-
Ma K, Simantov R, Zhang JC, et al. High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II. J Biol Chem 2000; 275: 15541-15548.
-
(2000)
J Biol Chem
, vol.275
, pp. 15541-15548
-
-
Ma, K.1
Simantov, R.2
Zhang, J.C.3
-
10
-
-
34547733912
-
Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
-
Sorice M, Longo A, Capozzi A, et al. Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum 2007; 56: 2687-2697.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2687-2697
-
-
Sorice, M.1
Longo, A.2
Capozzi, A.3
-
11
-
-
58849090583
-
Toll-like receptors: Another player in the pathogenesis of the anti-phospholipid syndrome
-
Raschi E, Borghi MO, Grossi C, et al. Toll-like receptors: another player in the pathogenesis of the anti-phospholipid syndrome. Lupus 2008; 17: 937-942.
-
(2008)
Lupus
, vol.17
, pp. 937-942
-
-
Raschi, E.1
Borghi, M.O.2
Grossi, C.3
-
12
-
-
77956395908
-
TLR2 is one of the endothelial receptors for beta 2-glycoprotein I
-
Alard JE, Gaillard F, Daridon C, et al. TLR2 is one of the endothelial receptors for beta 2-glycoprotein I. J Immunol 2010; 185: 1550-1557.
-
(2010)
J Immunol
, vol.185
, pp. 1550-1557
-
-
Alard, J.E.1
Gaillard, F.2
Daridon, C.3
-
13
-
-
0034990570
-
A specific ligand for beta(2)-glycoprotein I mediates autoantibody-dependent uptake of oxidized low density lipoprotein by macrophages
-
Kobayashi K, Matsuura E, Liu Q, et al. A specific ligand for beta(2)-glycoprotein I mediates autoantibody-dependent uptake of oxidized low density lipoprotein by macrophages. J Lipid Res 2001; 42: 697-709.
-
(2001)
J Lipid Res
, vol.42
, pp. 697-709
-
-
Kobayashi, K.1
Matsuura, E.2
Liu, Q.3
-
14
-
-
0141445991
-
Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein
-
Lutters BC, Derksen RH, Tekelenburg WL, et al. Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'. J Biol Chem 2003; 278: 33831-33838.
-
(2003)
E Receptor 2'. J Biol Chem
, vol.278
, pp. 33831-33838
-
-
Lutters, B.C.1
Derksen, R.H.2
Tekelenburg, W.L.3
-
15
-
-
77449133188
-
{beta}2 Glycoprotein I ({beta}2GPI) binds platelet factor 4 (PF4): Implications for the pathogenesis of antiphospholipid syndrome
-
Sikara MP, Routsias JG, Samiotaki M, et al. {beta}2 Glycoprotein I ({beta}2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome. Blood 2010; 115: 713-723.
-
(2010)
Blood
, vol.115
, pp. 713-723
-
-
Sikara, M.P.1
Routsias, J.G.2
Samiotaki, M.3
-
16
-
-
70350786142
-
Annexin A2 mediates anti-beta 2 GPI/beta 2 GPIinduced tissue factor expression on monocytes
-
Zhou H, Wang H, Li N, et al. Annexin A2 mediates anti-beta 2 GPI/beta 2 GPIinduced tissue factor expression on monocytes. Int J Mol Med 2009; 24: 557-562.
-
(2009)
Int J Mol Med
, vol.24
, pp. 557-562
-
-
Zhou, H.1
Wang, H.2
Li, N.3
-
17
-
-
78650831137
-
Toll-like receptor (TLR)-4 mediates anti-ß(2) GPI/ß(2) GPI-induced tissue factor expression in THP-1 cells
-
Zhou H, Yan Y, Xu G, et al. Toll-like receptor (TLR)-4 mediates anti-ß(2) GPI/ß(2) GPI-induced tissue factor expression in THP-1 cells. Clin Exp Immunol 2011; 163: 189-198.
-
(2011)
Clin Exp Immunol
, vol.163
, pp. 189-198
-
-
Zhou, H.1
Yan, Y.2
Xu, G.3
-
18
-
-
43049179999
-
LPS/TLR4 signal transduction pathway
-
Lu YC, Yeh WC, Ohashi PS. LPS/TLR4 signal transduction pathway. Cytokine 2008; 42: 145-151.
-
(2008)
Cytokine
, vol.42
, pp. 145-151
-
-
Lu, Y.C.1
Yeh, W.C.2
Ohashi, P.S.3
-
19
-
-
33646494167
-
Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering
-
Kobayashi M, Saitoh S, Tanimura N, et al. Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering. J Immunol 2006; 176: 6211-6218.
-
(2006)
J Immunol
, vol.176
, pp. 6211-6218
-
-
Kobayashi, M.1
Saitoh, S.2
Tanimura, N.3
-
20
-
-
67649386535
-
Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin
-
Resman N, Vasl J, Oblak A, et al. Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin. J Biol Chem 2009; 284: 15052-15060.
-
(2009)
J Biol Chem
, vol.284
, pp. 15052-15060
-
-
Resman, N.1
Vasl, J.2
Oblak, A.3
-
21
-
-
68649111238
-
TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice
-
Gao Y, Fang X, Tong Y, et al. TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice. Biomed Pharmacother 2009; 63: 442-450.
-
(2009)
Biomed Pharmacother
, vol.63
, pp. 442-450
-
-
Gao, Y.1
Fang, X.2
Tong, Y.3
-
22
-
-
79954577277
-
TLR-signaling networks: An integration of adaptor molecules, kinases, and cross-talk
-
Brown J, Wang H, Hajishengallis GN, et al. TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J Dent Res 2011; 90: 417-427.
-
(2011)
J Dent Res
, vol.90
, pp. 417-427
-
-
Brown, J.1
Wang, H.2
Hajishengallis, G.N.3
-
23
-
-
0028240827
-
Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells
-
Martin M, Böl GF, Eriksson A, et al. Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells. Eur J Immunol 1994; 24: 1566-1571.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1566-1571
-
-
Martin, M.1
Böl, G.F.2
Eriksson, A.3
-
24
-
-
0028982919
-
activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity
-
Croston GE, Cao Z, Goeddel DV. NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity. J Biol Chem 1995; 270: 16514-16517.
-
(1995)
J Biol Chem
, vol.270
, pp. 16514-16517
-
-
Croston, G.E.1
Cao, Z.2
Goeddel, D.V.3
Nf-Kappa, B.4
-
25
-
-
0033516561
-
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
-
Wesche H, Gao X, Li X, et al. IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J Biol Chem 1999; 274: 19403-19410.
-
(1999)
J Biol Chem
, vol.274
, pp. 19403-19410
-
-
Wesche, H.1
Gao, X.2
Li, X.3
-
26
-
-
1242272100
-
Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling
-
Kollewe C, Mackensen AC, Neumann D, et al. Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling. J Biol Chem 2004; 279: 5227-5236.
-
(2004)
J Biol Chem
, vol.279
, pp. 5227-5236
-
-
Kollewe, C.1
Mackensen, A.C.2
Neumann, D.3
-
27
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K, Hernandez LD, Galán JE, et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002; 110: 191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galán, J.E.3
-
28
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 2009; 27: 693-733.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
29
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L, Wang C, Spencer E, et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 2000; 103: 351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
-
30
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
-
Boone DL, Turer EE, Lee EG, et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004; 5: 1052-1060.
-
(2004)
Nat Immunol
, vol.5
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
-
31
-
-
23844461233
-
TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF
-
Takeshita F, Ishii KJ, Kobiyama K, et al. TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF. Eur J Immunol 2005; 35: 2477-2485.
-
(2005)
Eur J Immunol
, vol.35
, pp. 2477-2485
-
-
Takeshita, F.1
Ishii, K.J.2
Kobiyama, K.3
-
32
-
-
77955343208
-
Antiphospholipid antibodies affect human endometrial angiogenesis
-
Di Simone N, Di Nicuolo F, D'Ippolito S, et al. Antiphospholipid antibodies affect human endometrial angiogenesis. Biol Reprod 2010; 83: 212-219.
-
(2010)
Biol Reprod
, vol.83
, pp. 212-219
-
-
di Simone, N.1
di Nicuolo, F.2
D'ippolito, S.3
-
33
-
-
77956488547
-
Beta2-glycoprotein I can exist in 2 conformations: Implications for our understanding of the antiphospholipid syndrome
-
Agar C, van Os GM, Mörgelin M, et al. Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome. Blood 2010; 116: 1336-1343.
-
(2010)
Blood
, vol.116
, pp. 1336-1343
-
-
Agar, C.1
van Os, G.M.2
Mörgelin, M.3
-
34
-
-
14944367961
-
Annexin A2 mediates endothelial cell activation by antiphospholipid/ anti-beta2 glycoprotein I antibodies
-
Zhang J, McCrae KR. Annexin A2 mediates endothelial cell activation by antiphospholipid/ anti-beta2 glycoprotein I antibodies. Blood 2005; 105: 1964-1969.
-
(2005)
Blood
, vol.105
, pp. 1964-1969
-
-
Zhang, J.1
McCrae, K.R.2
-
35
-
-
34547914850
-
Involvement of annexin A2 in anti-beta2GPI /beta2GPI-induced tissue factor expression on monocytes
-
Zhou H, Ling S, Yu Y, et al. Involvement of annexin A2 in anti-beta2GPI /beta2GPI-induced tissue factor expression on monocytes. Cell Res 2007; 17: 737-739.
-
(2007)
Cell Res
, vol.17
, pp. 737-739
-
-
Zhou, H.1
Ling, S.2
Yu, Y.3
-
36
-
-
70449509134
-
Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
-
Romay-Penabad Z, Montiel-Manzano MG, Shilagard T, et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood 2009; 114: 3074-3083.
-
(2009)
Blood
, vol.114
, pp. 3074-3083
-
-
Romay-Penabad, Z.1
Montiel-Manzano, M.G.2
Shilagard, T.3
-
37
-
-
0037292275
-
Functional diversity and regulation of different interleukin- 1 receptor-associated kinase (IRAK) family members
-
Janssens S, Beyaert R. Functional diversity and regulation of different interleukin- 1 receptor-associated kinase (IRAK) family members. Mol Cell 2003; 11: 293-302.
-
(2003)
Mol Cell
, vol.11
, pp. 293-302
-
-
Janssens, S.1
Beyaert, R.2
-
38
-
-
0037528699
-
Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
-
Raschi E, Testoni C, Bosisio D, et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood 2003; 101: 3495-3500.
-
(2003)
Blood
, vol.101
, pp. 3495-3500
-
-
Raschi, E.1
Testoni, C.2
Bosisio, D.3
-
39
-
-
8344267910
-
The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-beta2Glycoprotein I antibodies
-
Bohgaki M, Atsumi T, Yamashita Y, et al. The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-beta2Glycoprotein I antibodies. Int Immunol 2004; 16: 1633-1641.
-
(2004)
Int Immunol
, vol.16
, pp. 1633-1641
-
-
Bohgaki, M.1
Atsumi, T.2
Yamashita, Y.3
-
40
-
-
77449113227
-
Annexin A2 tetramer activates human and murine macrophages through TLR4
-
Swisher JF, Burton N, Bacot SM, et al. Annexin A2 tetramer activates human and murine macrophages through TLR4. Blood 2010; 115: 549-558.
-
(2010)
Blood
, vol.115
, pp. 549-558
-
-
Swisher, J.F.1
Burton, N.2
Bacot, S.M.3
-
41
-
-
55549143335
-
Paclitaxel binding to human and murine MD-2
-
Zimmer SM, Liu J, Clayton JL, et al. Paclitaxel binding to human and murine MD-2. J Biol Chem 2008; 283: 27916-27926.
-
(2008)
J Biol Chem
, vol.283
, pp. 27916-27926
-
-
Zimmer, S.M.1
Liu, J.2
Clayton, J.L.3
-
42
-
-
55749105288
-
Taxanes inhibit human TLR4 signaling by binding to MD-2
-
Resman N, Gradisar H, Vasl J, et al. Taxanes inhibit human TLR4 signaling by binding to MD-2. FEBS Lett 2008; 582: 3929-3934.
-
(2008)
FEBS Lett
, vol.582
, pp. 3929-3934
-
-
Resman, N.1
Gradisar, H.2
Vasl, J.3
-
43
-
-
37649013951
-
Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel
-
Eisenreich A, Celebi O, Goldin-Lang P, et al. Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel. Int Immunopharmacol 2008; 8: 307-311.
-
(2008)
Int Immunopharmacol
, vol.8
, pp. 307-311
-
-
Eisenreich, A.1
Celebi, O.2
Goldin-Lang, P.3
-
44
-
-
62849102288
-
Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma
-
Noels H, Somers R, Liu H, et al. Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma. PLoS One 2009; 4: e4822.
-
(2009)
PLoS One
, vol.e4822
, pp. 4
-
-
Noels, H.1
Somers, R.2
Liu, H.3
-
45
-
-
0141682703
-
Ubiquitin activated tumor necrosis factor receptor associated factor-6 (TRAF6) is recycled via deubiquitination
-
Jensen LE, Whitehead AS. Ubiquitin activated tumor necrosis factor receptor associated factor-6 (TRAF6) is recycled via deubiquitination. FEBS Lett 2003; 553: 190-194.
-
(2003)
FEBS Lett
, vol.553
, pp. 190-194
-
-
Jensen, L.E.1
Whitehead, A.S.2
-
46
-
-
0026691240
-
The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity
-
Opipari AW Jr, Hu HM, Yabkowitz R, et al. The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity. J Biol Chem 1992; 267: 12424-12427.
-
(1992)
J Biol Chem
, vol.267
, pp. 12424-12427
-
-
Opipari Jr., A.W.1
Hu, H.M.2
Yabkowitz, R.3
-
47
-
-
67649778720
-
A20: Central gatekeeper in inflammation and immunity
-
Coornaert B, Carpentier I, Beyaert R. A20: central gatekeeper in inflammation and immunity. J Biol Chem 2009; 284: 8217-8221.
-
(2009)
J Biol Chem
, vol.284
, pp. 8217-8221
-
-
Coornaert, B.1
Carpentier, I.2
Beyaert, R.3
-
48
-
-
0037418749
-
Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein
-
O'Reilly SM, Moynagh PN. Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein. Biochem Biophys Res Commun 2003; 303: 586-593.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 586-593
-
-
O'Reilly, S.M.1
Moynagh, P.N.2
-
49
-
-
0032939356
-
The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6
-
Heyninck K, Beyaert R. The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6. FEBS Lett 1999; 442: 147-150.
-
(1999)
FEBS Lett
, vol.442
, pp. 147-150
-
-
Heyninck, K.1
Beyaert, R.2
-
50
-
-
39549107115
-
Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20
-
Turer EE, Tavares RM, Mortier E, et al. Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20. J Exp Med 2008; 205: 451-464.
-
(2008)
J Exp Med
, vol.205
, pp. 451-464
-
-
Turer, E.E.1
Tavares, R.M.2
Mortier, E.3
|