T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway

Science Translational Medicine

Volumn 6, Issue 235, 2014, Pages

  Bozec, Aline ^a   Zaiss, Mario M ^a,b   Kagwiria, Rosebeth ^a   Voll, Reinhard ^c   Rauh, Manfred ^a   Chen, Zhu ^a   Mueller Schmucker, Sandra ^a   Kroczek, Richard A ^d   Heinzerling, Lucie ^a   Moser, Muriel ^e   Mellor, Andrew L ^f   David, Jean Pierre ^g   Schett, Georg ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b EPFL   (Switzerland)

^c UNIVERSITY OF FREIBURG   (Germany)

^d ROBERT KOCH INSTITUTE   (Germany)

^e UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^f AUGUSTA UNIVERSITY   (United States)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; B7 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INDOLEAMINE 2,3 DIOXYGENASE; IPILIMUMAB; TRYPTOPHAN; CD86 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IMMUNOSTIMULATION; MOLECULAR MECHANICS; MONONUCLEAR CELL; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPENIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; ANIMAL; CYTOLOGY; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; ANTIGENS, CD80; ANTIGENS, CD86; CELL DIFFERENTIATION; CTLA-4 ANTIGEN; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; MICE; MICE, KNOCKOUT; NF-KAPPA B; OSTEOCLASTS; T-LYMPHOCYTES; TRYPTOPHAN;

EID: 84901044324     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3007764     Document Type: Article

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