Anticancer compound Oplopantriol A kills cancer cells through inducing ER stress and BH3 proteins Bim and Noxa

Cell Death and Disease

Volumn 5, Issue 4, 2014, Pages

  Jin, H R ^a   Liao, Y ^a   Li, X ^a   Zhang, Z ^b,c   Zhao, J ^a   Wang, C Z ^b,c   Huang, W H ^d   Li, S P ^d   Yuan, C S ^b,c   Du, W ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d China jack1987168 163com   (Macao)

Author keywords

Bim; ER stress; Noxa; Oplopantriol A; Unfolded protein response

Indexed keywords

ANTINEOPLASTIC AGENT; BIM PROTEIN; GLUCOSE REGULATED PROTEIN 78; OPLOPANTRIOL A; PROTEASOME; PROTEIN NOXA; UBIQUITIN; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG; 9,17-OCTADECADIEN-12,14- DIYNE-1,11,16-TRIOL; APOPTOSIS REGULATORY PROTEIN; BCL-2-LIKE PROTEIN 11; MCL1 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN; PMAIP1 PROTEIN, HUMAN; POLYACETYLENE DERIVATIVE; PROTEIN BCL 2; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CELL DEATH; CELL KILLING; COLORECTAL CANCER; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN SYNTHESIS; UNFOLDED PROTEIN RESPONSE; ANIMAL; DRUG EFFECTS; DRUG SCREENING; GENE SILENCING; METABOLISM; NUDE MOUSE; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MEMBRANE PROTEINS; MICE, NUDE; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; POLYACETYLENES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; UBIQUITINATED PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84901036444     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.169     Document Type: Article

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