Synthesis of new lipoic acid conjugates and evaluation of their free radical scavenging and neuroprotective activities

Chemical Biology and Drug Design

Volumn 83, Issue 6, 2014, Pages 688-696

  Bolognesi, Maria Laura ^a   Bergamini, Christian ^a   Fato, Romana ^a   Oiry, Joël ^b   Vasseur, Jean Jacques ^b   Smietana, Michael ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

Alzheimer's disease; antioxidant; ferrous chelation; lipoic acid; multitarget ligands

Indexed keywords

ASCORBIC ACID; CYSTEINE; DIHYDROLIPOATE; LIPOIC ACID CONJUGATE; NEUROPROTECTIVE AGENT; THIOCTIC ACID; TROLOX C; UNCLASSIFIED DRUG; SCAVENGER;

ABTS RADICAL SCAVENGING ASSAY; ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IRON CHELATION; NEUROPROTECTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; SYNTHESIS; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL SURVIVAL; FREE RADICAL SCAVENGERS; HUMANS; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; THIOCTIC ACID;

EID: 84901022657     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12282     Document Type: Article

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