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Volumn 5, Issue 5, 2014, Pages

Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growth

Author keywords

ErbB2; ErbB2 ligand; Her2; PEPD; Prolidase

Indexed keywords

DIMER; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HOMODIMER; MONOMER; PROLINE DIPEPTIDASE;

EID: 84900986976     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.187     Document Type: Article
Times cited : (21)

References (40)
  • 1
    • 0022406444 scopus 로고
    • Amplification of a novel v-erbB-related gene in a human mammary carcinoma
    • King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 1985; 229: 974-976.
    • (1985) Science , vol.229 , pp. 974-976
    • King, C.R.1    Kraus, M.H.2    Aaronson, S.A.3
  • 2
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235: 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 3
    • 66249091930 scopus 로고    scopus 로고
    • The HER- 2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine
    • Ross JS, Slodkowska EA, Symmans WF, Pusztai L, Ravdin PM, Hortobagyi GN. The HER- 2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist 2009; 14: 320-368.
    • (2009) Oncologist , vol.14 , pp. 320-368
    • Ross, J.S.1    Slodkowska, E.A.2    Symmans, W.F.3    Pusztai, L.4    Ravdin, P.M.5    Hortobagyi, G.N.6
  • 4
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel CL, Cobleigh MA, Tripathy D, Gutheil JC, Harris LN, Fehrenbacher L et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002; 20: 719-726.
    • (2002) J Clin Oncol , vol.20 , pp. 719-726
    • Vogel, C.L.1    Cobleigh, M.A.2    Tripathy, D.3    Gutheil, J.C.4    Harris, L.N.5    Fehrenbacher, L.6
  • 6
    • 73949090721 scopus 로고    scopus 로고
    • Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: An institutionalbased review
    • Dawood S, Broglio K, Buzdar AU, Hortobagyi GN, Giordano SH. Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: An institutionalbased review. J Clin Oncol 2010; 28: 92-98.
    • (2010) J Clin Oncol , vol.28 , pp. 92-98
    • Dawood, S.1    Broglio, K.2    Buzdar, A.U.3    Hortobagyi, G.N.4    Giordano, S.H.5
  • 7
    • 18344390418 scopus 로고    scopus 로고
    • ERBβ receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA. ERBβ receptors and cancer: The complexity of targeted inhibitors. Nat Rev Cancer 2005; 5: 341-354.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 8
    • 0022388402 scopus 로고
    • The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor
    • Schechter AL, Hung MC, Vaidyanathan L, Weinberg RA, Yang-Feng TL, Francke U et al. The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. Science 1985; 229: 976-978.
    • (1985) Science , vol.229 , pp. 976-978
    • Schechter, A.L.1    Hung, M.C.2    Vaidyanathan, L.3    Weinberg, R.A.4    Yang-Feng, T.L.5    Francke, U.6
  • 9
    • 0022399581 scopus 로고
    • Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
    • Coussens L, Yang-Feng TL, Liao YC, Chen E, Gray A, McGrath J et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985; 230: 1132-1139.
    • (1985) Science , vol.230 , pp. 1132-1139
    • Coussens, L.1    Yang-Feng, T.L.2    Liao, Y.C.3    Chen, E.4    Gray, A.5    McGrath, J.6
  • 11
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all Erbβ receptors, is a mediator of lateral signaling
    • Graus-Porta D, Beerli RR, Daly JM, Hynes NE. ErbB-2, the preferred heterodimerization partner of all Erbβ receptors, is a mediator of lateral signaling. EMBO J 1997; 16: 1647-1655.
    • (1997) EMBO J , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 12
    • 84873829861 scopus 로고    scopus 로고
    • Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling
    • Yang L, Li Y, Ding Y, Choi KS, Kazim AL, Zhang Y. Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling. J Biol Chem 2013; 288: 2365-2375.
    • (2013) J Biol Chem , vol.288 , pp. 2365-2375
    • Yang, L.1    Li, Y.2    Ding, Y.3    Choi, K.S.4    Kazim, A.L.5    Zhang, Y.6
  • 13
  • 14
    • 0033009389 scopus 로고    scopus 로고
    • Binding specificities and affinities of egf domains for Erbβ receptors
    • Jones JT, Akita RW, Sliwkowski MX. Binding specificities and affinities of egf domains for Erbβ receptors. FEBS Lett 1999; 447: 227-231.
    • (1999) FEBS Lett , vol.447 , pp. 227-231
    • Jones, J.T.1    Akita, R.W.2    Sliwkowski, M.X.3
  • 16
    • 0035874981 scopus 로고    scopus 로고
    • Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
    • Molina MA, Codony-Servat J, Albanell J, Rojo F, Arribas J, Baselga J. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res 2001; 61: 4744-4749.
    • (2001) Cancer Res , vol.61 , pp. 4744-4749
    • Molina, M.A.1    Codony-Servat, J.2    Albanell, J.3    Rojo, F.4    Arribas, J.5    Baselga, J.6
  • 17
    • 55449129956 scopus 로고    scopus 로고
    • Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells
    • Barr DJ, Ostermeyer-Fay AG, Matundan RA, Brown DA. Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells. J Cell Sci 2008; 121: 3155-3166.
    • (2008) J Cell Sci , vol.121 , pp. 3155-3166
    • Barr, D.J.1    Ostermeyer-Fay, A.G.2    Matundan, R.A.3    Brown, D.A.4
  • 18
    • 38349175328 scopus 로고    scopus 로고
    • Mutational activation of ErbB2 reveals a new protein kinase autoinhibition mechanism
    • Fan YX, Wong L, Ding J, Spiridonov NA, Johnson RC, Johnson GR. Mutational activation of ErbB2 reveals a new protein kinase autoinhibition mechanism. J Biol Chem 2008; 283: 1588-1596.
    • (2008) J Biol Chem , vol.283 , pp. 1588-1596
    • Fan, Y.X.1    Wong, L.2    Ding, J.3    Spiridonov, N.A.4    Johnson, R.C.5    Johnson, G.R.6
  • 19
    • 0029956462 scopus 로고    scopus 로고
    • Expression and molecular analysis of mutations in prolidase deficiency
    • Ledoux P, Scriver CR, Hechtman P. Expression and molecular analysis of mutations in prolidase deficiency. Am J Hum Genet 1996; 59: 1035-1039.
    • (1996) Am J Hum Genet , vol.59 , pp. 1035-1039
    • Ledoux, P.1    Scriver, C.R.2    Hechtman, P.3
  • 20
    • 15944406764 scopus 로고    scopus 로고
    • PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
    • Gao T, Furnari F, Newton AC. PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol Cell 2005; 18: 13-24.
    • (2005) Mol Cell , vol.18 , pp. 13-24
    • Gao, T.1    Furnari, F.2    Newton, A.C.3
  • 21
    • 0037929502 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity
    • Donella-Deana A, Cesaro L, Sarno S, Ruzzene M, Brunati AM, Marin O et al. Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity. Biochem J 2003; 372: 841-849.
    • (2003) Biochem J , vol.372 , pp. 841-849
    • Donella-Deana, A.1    Cesaro, L.2    Sarno, S.3    Ruzzene, M.4    Brunati, A.M.5    Marin, O.6
  • 22
    • 78249236544 scopus 로고    scopus 로고
    • Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation
    • Liang K, Esteva FJ, Albarracin C, Stemke-Hale K, Lu Y, Bianchini G et al. Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation. Cancer Cell 2010; 18: 423-435.
    • (2010) Cancer Cell , vol.18 , pp. 423-435
    • Liang, K.1    Esteva, F.J.2    Albarracin, C.3    Stemke-Hale, K.4    Lu, Y.5    Bianchini, G.6
  • 23
    • 0034693806 scopus 로고    scopus 로고
    • Selected glimpses into the activation and function of Src kinase
    • Bjorge JD, Jakymiw A, Fujita DJ. Selected glimpses into the activation and function of Src kinase. Oncogene 2000; 19: 5620-5635.
    • (2000) Oncogene , vol.19 , pp. 5620-5635
    • Bjorge, J.D.1    Jakymiw, A.2    Fujita, D.J.3
  • 25
    • 0141994730 scopus 로고    scopus 로고
    • Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades
    • Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D et al. Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades. J Biol Chem 2003; 278: 40057-40066.
    • (2003) J Biol Chem , vol.278 , pp. 40057-40066
    • Lu, Y.1    Yu, Q.2    Liu, J.H.3    Zhang, J.4    Wang, H.5    Koul, D.6
  • 26
    • 0028047315 scopus 로고
    • Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity
    • Muthuswamy SK, Siegel PM, Dankort DL, Webster MA, Muller WJ. Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity. Mol Cell Biol 1994; 14: 735-743.
    • (1994) Mol Cell Biol , vol.14 , pp. 735-743
    • Muthuswamy, S.K.1    Siegel, P.M.2    Dankort, D.L.3    Webster, M.A.4    Muller, W.J.5
  • 27
    • 0032497249 scopus 로고    scopus 로고
    • C-Src activation by ErbB2 leads to attachment-independent growth of human breast epithelial cells
    • Sheffield LG. C-Src activation by ErbB2 leads to attachment-independent growth of human breast epithelial cells. Biochem Biophys Res Commun 1998; 250: 27-31.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 27-31
    • Sheffield, L.G.1
  • 28
    • 48549088895 scopus 로고    scopus 로고
    • Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
    • Sigismund S, Argenzio E, Tosoni D, Cavallaro E, Polo S, Di Fiore PP. Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell 2008; 15: 209-219.
    • (2008) Dev Cell , vol.15 , pp. 209-219
    • Sigismund, S.1    Argenzio, E.2    Tosoni, D.3    Cavallaro, E.4    Polo, S.5    Di Fiore, P.P.6
  • 30
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • Nagata Y, Lan KH, Zhou X, Tan M, Esteva FJ, Sahin AA et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004; 6: 117-127.
    • (2004) Cancer Cell , vol.6 , pp. 117-127
    • Nagata, Y.1    Lan, K.H.2    Zhou, X.3    Tan, M.4    Esteva, F.J.5    Sahin, A.A.6
  • 31
    • 0037434791 scopus 로고    scopus 로고
    • Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
    • Cho HS, Mason K, Ramyar KX, Stanley AM, Gabelli SB, Denney DW Jr et al. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab. Nature 2003; 421: 756-760.
    • (2003) Nature , vol.421 , pp. 756-760
    • Cho, H.S.1    Mason, K.2    Ramyar, K.X.3    Stanley, A.M.4    Gabelli, S.B.5    Denney Jr., D.W.6
  • 32
    • 0035553174 scopus 로고    scopus 로고
    • The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo
    • Rusnak DW, Lackey K, Affleck K, Wood ER, Alligood KJ, Rhodes N et al. The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo. Mol Cancer Ther 2001; 1: 85-94.
    • (2001) Mol Cancer Ther , vol.1 , pp. 85-94
    • Rusnak, D.W.1    Lackey, K.2    Affleck, K.3    Wood, E.R.4    Alligood, K.J.5    Rhodes, N.6
  • 33
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas CF 3rd, Hynes NE. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc Natl Acad Sci USA 2003; 100: 8933-8938.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3    Koziczak, M.4    Barbas III, C.F.5    Hynes, N.E.6
  • 34
    • 48649092620 scopus 로고    scopus 로고
    • A central role for HER3 in HER2-amplified breast cancer: Implications for targeted therapy
    • Lee-Hoeflich ST, Crocker L, Yao E, Pham T, Munroe X, Hoeflich KP et al. A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy. Cancer Res 2008; 68: 5878-5887.
    • (2008) Cancer Res , vol.68 , pp. 5878-5887
    • Lee-Hoeflich, S.T.1    Crocker, L.2    Yao, E.3    Pham, T.4    Munroe, X.5    Hoeflich, K.P.6
  • 35
    • 84899928188 scopus 로고    scopus 로고
    • Factor-Xa inhibitors protect against systemic oxidant damage induced by peripheral-ischemia reperfusion
    • Caliskan A, Yavuz C, Karahan O, Yazici S, Guclu O, Demirtas S et al. Factor-Xa inhibitors protect against systemic oxidant damage induced by peripheral-ischemia reperfusion. J Thromb Thrombolysis 2014; 37: 464-468.
    • (2014) J Thromb Thrombolysis , vol.37 , pp. 464-468
    • Caliskan, A.1    Yavuz, C.2    Karahan, O.3    Yazici, S.4    Guclu, O.5    Demirtas, S.6
  • 36
    • 0038517977 scopus 로고    scopus 로고
    • Serum prolidase i activity and some bone metabolic markers in patients with breast cancer: In relation to menopausal status
    • Kir ZO, Oner P, Iyidogan YO, Turkmen S, Kocak H, Koser M et al. Serum prolidase I activity and some bone metabolic markers in patients with breast cancer: In relation to menopausal status. Clin Biochem 2003; 36: 289-294.
    • (2003) Clin Biochem , vol.36 , pp. 289-294
    • Kir, Z.O.1    Oner, P.2    Iyidogan, Y.O.3    Turkmen, S.4    Kocak, H.5    Koser, M.6
  • 37
    • 84862289057 scopus 로고    scopus 로고
    • Serum prolidase activity, oxidative stress, and nitric oxide levels in patients with bladder cancer
    • Gecit I, Aslan M, Gunes M, Pirincci N, Esen R, Demir H et al. Serum prolidase activity, oxidative stress, and nitric oxide levels in patients with bladder cancer. J Cancer Res Clin Oncol 2012; 138: 739-743.
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 739-743
    • Gecit, I.1    Aslan, M.2    Gunes, M.3    Pirincci, N.4    Esen, R.5    Demir, H.6
  • 38
    • 73449125189 scopus 로고    scopus 로고
    • Serum prolidase activity and oxidative status in patients with stage i endometrial cancer
    • Arioz DT, Camuzcuoglu H, Toy H, Kurt S, Celik H, Aksoy N. Serum prolidase activity and oxidative status in patients with stage I endometrial cancer. Int J Gynecol Cancer 2009; 19: 1244-1247.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 1244-1247
    • Arioz, D.T.1    Camuzcuoglu, H.2    Toy, H.3    Kurt, S.4    Celik, H.5    Aksoy, N.6
  • 39
    • 84871905514 scopus 로고    scopus 로고
    • Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism
    • Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK et al. Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism. Nature Commun 2012; 3: 1271.
    • (2012) Nature Commun , vol.3 , pp. 1271
    • Ding, Y.1    Liu, Z.2    Desai, S.3    Zhao, Y.4    Liu, H.5    Pannell, L.K.6
  • 40
    • 84864359086 scopus 로고    scopus 로고
    • Mechanism of chemical activation of Nrf2
    • Li Y, Paonessa JD, Zhang Y. Mechanism of chemical activation of Nrf2. PLoS One 2012; 7: e35122.
    • (2012) PLoS One , vol.7
    • Li, Y.1    Paonessa, J.D.2    Zhang, Y.3


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