Examining strategies to facilitate vitamin B1 biofortification of plants by genetic engineering

Frontiers in Plant Science

Volumn 4, Issue MAY, 2013, Pages

  Pourcel, Lucille ^a   Moulin, Michael ^a   Fitzpatrick, Teresa B ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Biofortification; Genetic engineering; HET; HMP; Riboswitch; Thiamin

Indexed keywords

EID: 84900841545     PISSN: None     EISSN: 1664462X     Source Type: Journal    
DOI: 10.3389/fpls.2013.00160     Document Type: Article

References (47)

1. Ahn, I.-P., Kim, S., and Lee, Y.-H. (2005). Vitamin B1 functions as an activator of plant disease resistance. Plant Physiol. 138, 1505-1515.
2. Ajjawi, I., Tsegaye, Y., and Shintani, D. (2007a). Determination of the genetic, molecular, and biochemical basis of the Arabidopsis thaliana thiamin auxotroph th1. Arch. Biochem. Biophys. 459, 107-114.
3. Ajjawi, I., Rodriguez Milla, M. A., Cushman, J., and Shintani, D. K. (2007b). Thiamin pyrophosphokinase is required for thiamin cofactor activation in Arabidopsis. Plant Mol. Biol. 65, 151-162.
4. Balmer, Y., Koller, A., del Val, G., Manieri, W., Schürmann, P., and Buchanan, B. B. (2003). Proteomics gives insight into the regulatory function of chloroplast thioredoxins. Proc. Natl. Acad. Sci. U.S.A. 100, 370-375.
5. Balmer, Y., Vensel, W. H., Cai, N., Manieri, W., Schürmann, P., Hurkman, W. J., et al. (2006). A complete ferredoxin/thioredoxin system regulates fundamental processes in amyloplasts. Proc. Natl. Acad. Sci. U.S.A. 103, 2988-2993.
6. Belanger, F. C., Leustek, T., Chu, B., and Kriz, A. L. (1995). Evidence for the thiamine biosynthetic pathway in higher plant plastids and its developmental regulation. Plant Mol. Biol. 29, 809-821.
7. Bettendorff, L., Wirtzfeld, B., Makarchikov, A. F., Mazzucchelli, G., Frédérich, M., Gigliobianco, T., et al. (2007). Discovery of a natural thiamine adenine nucleotide. Nat. Chem. Biol. 3, 211-212.
8. Bocobza, S. E., Adato, A., Mandel, T., Shapira, M., Nudler, E., and Aharoni, A. (2007). Riboswitch-dependent gene regulation and its evolution in the plant kingdom. Genes Dev. 21, 2874-2879.
9. Bocobza, S. E., Malitsky, S., Araújo, W. L., Nunes-Nesi, A., Meir, S., Shapira, M., et al. (2013). Orchestration of thiamin biosynthesis and central metabolism by combined action of the thiamin pyrophosphate riboswitch and the circadian clock in Arabidopsis. Plant Cell 25, 288-307.
10. Breaker, R. R. (2011). Riboswitches and the RNA world. Cold Spring Harb. Perspect. Biol. 1, 4.
11. Chabregas, S. M., Luche, D. D., Farias, L. P., Ribeiro, A. F., van Sluys, M.-A., Menck, C. F. M., et al. (2001). Dual targeting properties of the N-terminal signal sequence of Arabidopsis thaliana THI1 protein to mitochondria and chloroplasts. Plant Mol. Biol. 46, 639-650.
12. Chatterjee, A., Abeydeera, N. D., Bale, S., Pai, P. J., Dorrestein, P. C., Russell, D. H., et al. (2011). Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase. Nature 478, 542-546.
13. Chatterjee, A., Li, Y., Zhang, Y., Grove, T. L., Lee, M., Krebs, C., et al. (2008). Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily. Nat. Chem. Biol. 4, 758-765.
14. Feenstra, W. J. (1964). Isolation of nutritional mutants in Arabidopsis thaliana. Genetica 35, 259-269.
15. Fitzpatrick, T. B., Basset, G. J., Borel, P., Carrari, F., DellaPenna, D., Fraser, P. D., et al. (2012). Vitamin deficiencies in humans: can plant science help? Plant Cell 24, 395-414.
16. Funk, C. (1912). The etiology of the deficiency diseases. J. State Med. 20, 341-368.
17. Gangolf, M., Wins, P., Thiry, M., El Moualij, B., and Bettendorff, L. (2010). Thiamine triphosphate synthesis in rat brain occurs in mitochondria and is coupled to the respiratory chain. J. Biol. Chem. 285, 583-594.
18. Golda, A., Szyniarowski, P., Ostrowska, K., Kozik, A., and Rapala-Kozik, M. (2004). Thiamine binding and metabolism in germinating seeds of selected cereals and legumes. Plant Physiol. Biochem. 42, 187-195.
19. Goyer, A. (2010). Thiamine in plants: aspects of its metabolism and functions. Phytochemistry 71, 1615-1624.
20. Goyer, A., and Sweek, K. (2011). Genetic diversity of thiamin and folate in primitive cultivated and wild potato (Solanum) species. J. Agric. Food Chem. 59, 13072-13080.
21. Harper, C. G., Sheedy, D. L., Lara, A. I., Garrick, T. M., Hilton, J. M., and Raisanen, J. (1998). Prevalence of Wernicke-Korsakoff syndrome in Australia: has thiamine fortification made a difference? Med. J. Aust. 168, 542-545.
22. Hazra, A., Chatterjee, A., and Begley, T. P. (2009). Biosynthesis of the thiamin thiazole in Bacillus subtilis: identification of the product of the thiazole synthase-catalyzed reaction. J. Am. Chem. Soc. 131, 3225-3229.
23. Juillard, J.-H., and Douce, R. (1991). Biosynthesis of the thiazole moiety of thiamin (vitamin B1) in higher plant chloroplasts. Proc. Natl. Acad. Sci. U.S.A. 88, 2042-2045.
24. Komai, T., Kawai, K., and Shindo, H. (1974). Active transport of thiamine from rat small intestine. J. Nutr. Sci. Vitaminol. 20, 163-177.
25. Kong, D., Zhu, Y., Wu, H., Cheng, X., Liang, H., and Ling, H. Q. (2008). AtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thaliana. Cell Res. 18, 566-576.
26. Kowalska, E., and Kozik, A. (2008). The genes and enzymes involved in the biosynthesis of thiamin and thiamin diphosphate in yeasts. Cell. Mol. Biol. Lett. 13, 271-282.
27. Machado, C. R., de Oliveira, R. L., Boiteux, S., Praekelt, U. M., Meacock, P. A., and Menck, C. F. (1996). Thi1, a thiamine biosynthetic gene in Arabidopsis thaliana, complements bacterial defects in DNA repair. Plant Mol. Biol. 31, 585-593.
28. Martinez-Gomez, N. C., and Downs, D. M. (2008). ThiC is an [Fe-S] cluster protein that requires AdoMet to generate the 4-amino-5-hydroxymethyl-2-methylpyrimidine moiety in thiamin synthesis. Biochemistry 47, 9054-9056.
29. Mitsuda, H., Takii, Y., Iwami, K., Yasumoto, K., and Nakajima, K. (1979). Enzymatic formation of thiamine pyrophosphate in plants. Methods Enzymol. 62, 107-111.
30. Molin, W. T., and Fites, R. C. (1980). Isolation and characterization of thiamin pyrophosphotransferase from Glycine max seedlings. Plant Physiol. 66, 308-312.
31. Murashige, T., and Skoog, F. (1962). A revised medium for rapid growth of bioassays with tobacco tissue culture. Physiol. Plant 15, 473-497.
32. Nosaka, K. (2006). Recent progress in understanding thiamin biosynthesis and its genetic regulation in Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 72, 30-40.
33. Rapala-Kozik, M. (2011). "Vitamin B1 (thiamine): a cofactor for enzymes involved in the main metabolic pathways and an environmental stress protectant, " in Biosynthesis of Vitamins in Plants, eds F. Rebeille and R. Douce (London: Elsevier), 37-91.
34. Rapala-Kozik, M., Goda, A., and Kujda, M. (2009). Enzymes that control the thiamine diphosphate pool in plant tissues. Properties of thiamine pyrophosphokinase and thiamine-(di)phosphate phosphatase purified from Zea mays seedlings. Plant Physiol. Biochem. 47, 237-242.
35. Rapala-Kozik, M., Kowalska, E., and Ostrowska, K. (2008). Modulation of thiamine metabolism in Zea maysseedlings under conditions of abiotic stress. J. Exp. Bot. 59, 4133-4143.
36. Rapala-Kozik, M., Olczak, M., Ostrowska, K., Starosta, A., and Kozik, A. (2007). Molecular characterization of the thi3 gene involved in thiamine biosynthesis in Zea mays: cDNA sequence and enzymatic and structural properties of the recombinant bifunctional protein with 4-amino-5-hydroxymethyl-2-methylpyrimidine (phosphate) kinase and thiamine monophosphate synthase activities. Biochem. J. 408, 149-159.
37. Rapala-Kozik, M., Wolak, N., Kujda, M., and Banas, A. K. (2012). The upregulation of thiamine (vitamin B-1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response. BMC Plant Biol. 12:2. doi: 10.1186/1471-2229-12-2
38. Raschke, M., Bürkle, L., Müller, N., Nunes-Nesi, A., Fernie, A. R., Arigoni, D., et al. (2007). Vitamin B1 biosynthesis in plants requires the essential iron sulfur cluster protein, THIC. Proc. Natl. Acad. Sci. U.S.A. 104, 19637-19642.
39. Ribeiro, D. T., Farias, L. P., de Almeida, J. D., Kashiwabara, P. M., Ribeiro, A. F., Silva-Filho, M. C., et al. (2005). Functional characterization of the thi1 promoter region from Arabidopsis thaliana. J. Exp. Bot. 56, 1797-1804.
40. Said, H. M., Ortiz, A., Kumar, C. K., Chatterjee, N., Dudeja, P. K., and Rubin, S. (1999). Transport of thiamine in human intestine: mechanism and regulation in intestinal epithelial cell model Caco-2. Am. J. Physiol. 277, 645-651.
41. Sudarsan, N., Barrick, J. E., and Breaker, R. R. (2003). Metabolite-binding RNA domains are present in the genes of eukaryotes. RNA 9, 644-647.
42. Tunc-Ozdemir, M., Miller, G., Song, L., Kim, J., Sodek, A., Koussevitzky, S., et al. (2009). Thiamin confers enhanced tolerance to oxidative stress in Arabidopsis. Plant Physiol. 151, 421-432.
43. Wachter, A., Tunc-Ozdemir, M., Grove, B. C., Green, P. J., Shintani, D. K., and Breaker, R. R. (2007). Riboswitch control of gene expression in plants by splicing and alternative 3′ end processing of mRNAs. Plant Cell 19, 3437-3450.
44. Wang, G., Ding, X., Yuan, M., Qiu, D., Li, X., Xu, C., et al. (2006). Dual function of rice OsDR8 gene in disease resistance and thiamine accumulation. Plant Mol. Biol. 60, 437-449.
45. Watanabe, K., Nishida, N., Adachi, T., Ueda, M., Mitsunga, T., and Kawamura, Y. (2004). Accumulation and degradation of thiamin-binding protein and level of thiamin in wheat seeds during seed maturation and germination. Biosci. Biotechnol. Biochem. 68, 1243-1248.
46. Winkler, W., Nahvi, A., and Breaker, R. R. (2002). Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression. Nature 419, 952-956.
47. Ye, X., Al-Babili, S., Klöti, A., Zhang, J., Lucca, P., Beyer, P., et al. (2000). Engineering the provitamin A (β-carotene) biosynthetic pathway into 563 (carotenoid-free) rice endosperm. Science 287, 303-305.