메뉴 건너뛰기




Volumn 13, Issue 3, 2014, Pages 240-248

Scutellaria barbata D Don inhibits colorectal cancer growth via suppression of multiple signaling pathways

Author keywords

anticancer; apoptosis; colorectal cancer; proliferation; Scutellaria barbata D Don; signaling pathway

Indexed keywords

ALCOHOL; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; SCUTELLARIA BARBATA EXTRACT; SONIC HEDGEHOG PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

EID: 84900808553     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735413508811     Document Type: Article
Times cited : (39)

References (31)
  • 2
    • 0036955756 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer: Current status and future prospects
    • Gustin DM, Brenner DE. Chemoprevention of colon cancer: current status and future prospects. Cancer Metastasis Rev. 2002 ; 21: 323-348
    • (2002) Cancer Metastasis Rev , vol.21 , pp. 323-348
    • Gustin, D.M.1    Brenner, D.E.2
  • 3
    • 84861553415 scopus 로고    scopus 로고
    • Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway
    • Cai Q, Lin J, Wei L, et al. Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway. Int J Mol Sci. 2012 ; 13: 6117-6128
    • (2012) Int J Mol Sci , vol.13 , pp. 6117-6128
    • Cai, Q.1    Lin, J.2    Wei, L.3
  • 4
    • 25444454543 scopus 로고    scopus 로고
    • New and old functions of STAT3: A pivotal target for individualized treatment of cancer
    • Inghirami G, Chiarle R, Simmons WJ, Piva R, Schlessinger K, Levy DE. New and old functions of STAT3: a pivotal target for individualized treatment of cancer. Cell Cycle. 2005 ; 4: 1131-1133
    • (2005) Cell Cycle , vol.4 , pp. 1131-1133
    • Inghirami, G.1    Chiarle, R.2    Simmons, W.J.3    Piva, R.4    Schlessinger, K.5    Levy, D.E.6
  • 5
    • 33645839013 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs
    • Klampfer L. Signal transducers and activators of transcription (STATs): novel targets of chemopreventive and chemotherapeutic drugs. Curr Cancer Drug Targets. 2006 ; 6: 107-121
    • (2006) Curr Cancer Drug Targets , vol.6 , pp. 107-121
    • Klampfer, L.1
  • 6
    • 0036782706 scopus 로고    scopus 로고
    • Transcription factors as targets for cancer therapy
    • Darnell JE. Transcription factors as targets for cancer therapy. Nat Rev Cancer. 2002 ; 2: 740-749
    • (2002) Nat Rev Cancer , vol.2 , pp. 740-749
    • Darnell, J.E.1
  • 7
    • 69149098253 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription-3, inflammation, and cancer: How intimate is the relationship?
    • Aggarwal BB, Kunnumakkara AB, Harikumar KB, et al. Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?. Ann N Y Acad Sci. 2009 ; 1171: 59-76
    • (2009) Ann N y Acad Sci , vol.1171 , pp. 59-76
    • Aggarwal, B.B.1    Kunnumakkara, A.B.2    Harikumar, K.B.3
  • 8
    • 33847406439 scopus 로고    scopus 로고
    • Activation of STAT3 is a marker of poor prognosis in human colorectal cancer
    • Kusaba T, Nakayama T, Yamazumi K, et al. Activation of STAT3 is a marker of poor prognosis in human colorectal cancer. Oncol Rep. 2006 ; 15: 1445-1451
    • (2006) Oncol Rep , vol.15 , pp. 1445-1451
    • Kusaba, T.1    Nakayama, T.2    Yamazumi, K.3
  • 9
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • Grivennikov S, Karin E, Terzic J, et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell. 2009 ; 15: 103-113
    • (2009) Cancer Cell , vol.15 , pp. 103-113
    • Grivennikov, S.1    Karin, E.2    Terzic, J.3
  • 10
    • 58649100056 scopus 로고    scopus 로고
    • Inflammation and cancer: IL-6 and STAT3 complete the link
    • Bromberg J, Wang TC. Inflammation and cancer: IL-6 and STAT3 complete the link. Cancer Cell. 2009 ; 15: 79-80
    • (2009) Cancer Cell , vol.15 , pp. 79-80
    • Bromberg, J.1    Wang, T.C.2
  • 11
    • 40149094813 scopus 로고    scopus 로고
    • Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells
    • Xiong H, Zhang Z, Tian X, et al. Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. Neoplasia. 2008 ; 10: 287-297
    • (2008) Neoplasia , vol.10 , pp. 287-297
    • Xiong, H.1    Zhang, Z.2    Tian, X.3
  • 12
    • 0034722894 scopus 로고    scopus 로고
    • Development of anticancer drugs targeting the MAP kinase pathway
    • Sebolt-Leopold JS. Development of anticancer drugs targeting the MAP kinase pathway. Oncogene. 2000 ; 19: 6594-6599
    • (2000) Oncogene , vol.19 , pp. 6594-6599
    • Sebolt-Leopold, J.S.1
  • 13
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG. The MAPK signaling cascade. FASEB J. 1995 ; 9: 726-735
    • (1995) FASEB J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 14
    • 1842482350 scopus 로고    scopus 로고
    • Regulation of phorbol estermediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-κB-dependent pathway
    • Wang X, Wang Q, Hu W, Evers BM. Regulation of phorbol estermediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-κB- dependent pathway. Oncogene. 2004 ; 23: 1885-1895
    • (2004) Oncogene , vol.23 , pp. 1885-1895
    • Wang, X.1    Wang, Q.2    Hu, W.3    Evers, B.M.4
  • 15
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene. 2007 ; 26: 3291-3310
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 16
    • 39149098194 scopus 로고    scopus 로고
    • Natural products as leads to anticancer drugs
    • Gordaliza M. Natural products as leads to anticancer drugs. Clin Transl Oncol. 2007 ; 9: 767-776
    • (2007) Clin Transl Oncol , vol.9 , pp. 767-776
    • Gordaliza, M.1
  • 17
    • 80052410901 scopus 로고    scopus 로고
    • Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways
    • Prakobwong S, Gupta SC, Kim JH, et al. Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways. Carcinogenesis. 2011 ; 32: 1372-1380
    • (2011) Carcinogenesis , vol.32 , pp. 1372-1380
    • Prakobwong, S.1    Gupta, S.C.2    Kim, J.H.3
  • 18
    • 84866392802 scopus 로고    scopus 로고
    • Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: Chemosensitization with capecitabine
    • Prasad S, Yadav VR, Sung B, et al. Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine. Clin Cancer Res. 2012 ; 18: 4942-4953
    • (2012) Clin Cancer Res , vol.18 , pp. 4942-4953
    • Prasad, S.1    Yadav, V.R.2    Sung, B.3
  • 19
    • 77956262888 scopus 로고    scopus 로고
    • Beijing, China: Chinese Medical Science and Technology Press;
    • Pharmacopoeia of the People's Republic of China. Beijing, China: Chinese Medical Science and Technology Press ; 2010: 109-110.
    • (2010) Pharmacopoeia of the People's Republic of China , pp. 109-110
  • 20
    • 84860389865 scopus 로고    scopus 로고
    • Scutellaria barbata D. Don induces apoptosis of human colon carcinoma cell through activation of the mitochondrion-dependent pathway
    • Wei L, Chen Y, Lin J, et al. Scutellaria barbata D. Don induces apoptosis of human colon carcinoma cell through activation of the mitochondrion-dependent pathway. J Med Plants Res. 2011 ; 5: 1962-1970
    • (2011) J Med Plants Res , vol.5 , pp. 1962-1970
    • Wei, L.1    Chen, Y.2    Lin, J.3
  • 21
    • 84860291741 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis by Scutellaria barbata D. Don via suppressing proliferation, migration and tube formation of endothelial cells and downregulation of the expression of VEGF-A in cancer cells
    • Wei L, Lin J, Xu W, Hong Z, Liu X, Peng J. Inhibition of tumor angiogenesis by Scutellaria barbata D. Don via suppressing proliferation, migration and tube formation of endothelial cells and downregulation of the expression of VEGF-A in cancer cells. J Med Plants Res. 2011 ; 5: 3260-3268
    • (2011) J Med Plants Res , vol.5 , pp. 3260-3268
    • Wei, L.1    Lin, J.2    Xu, W.3    Hong, Z.4    Liu, X.5    Peng, J.6
  • 22
    • 84865000632 scopus 로고    scopus 로고
    • Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer
    • Wei L, Lin J, Xu W, et al. Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer. Int J Mol Sci. 2012 ; 13: 9419-9430
    • (2012) Int J Mol Sci , vol.13 , pp. 9419-9430
    • Wei, L.1    Lin, J.2    Xu, W.3
  • 23
    • 84874720570 scopus 로고    scopus 로고
    • Scutellaria barbata D. Don induces G1/S arrest via modulation of p53 and Akt pathways in human colon carcinoma cells
    • Wei LH, Lin JM, Wu GW, et al. Scutellaria barbata D. Don induces G1/S arrest via modulation of p53 and Akt pathways in human colon carcinoma cells. Oncol Rep. 2013 ; 29: 1623-1628
    • (2013) Oncol Rep , vol.29 , pp. 1623-1628
    • Wei, L.H.1    Lin, J.M.2    Wu, G.W.3
  • 24
    • 63349110389 scopus 로고    scopus 로고
    • Thymosin β-10 is aberrantly expressed in pancreatic cancer and induces JNK activation
    • Li M, Zhang Y, Zhai Q, et al. Thymosin β-10 is aberrantly expressed in pancreatic cancer and induces JNK activation. Cancer Invest. 2009 ; 27: 251-256
    • (2009) Cancer Invest , vol.27 , pp. 251-256
    • Li, M.1    Zhang, Y.2    Zhai, Q.3
  • 25
    • 61849148824 scopus 로고    scopus 로고
    • Natural products and drug discovery
    • Ji HF, Li XJ, Zhang HY. Natural products and drug discovery. EMBO Rep. 2009 ; 10: 194-200
    • (2009) EMBO Rep , vol.10 , pp. 194-200
    • Ji, H.F.1    Li, X.J.2    Zhang, H.Y.3
  • 26
    • 0034489957 scopus 로고    scopus 로고
    • Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine
    • Lee KH. Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine. Public Health Nutr. 2000 ; 3: 515-522
    • (2000) Public Health Nutr , vol.3 , pp. 515-522
    • Lee, K.H.1
  • 27
    • 84880126303 scopus 로고    scopus 로고
    • Treatment of food anaphylaxis with traditional Chinese herbal remedies: From mouse model to human clinical trials
    • Wang J. Treatment of food anaphylaxis with traditional Chinese herbal remedies: from mouse model to human clinical trials. Curr Opin Allergy Clin Immunol. 2013 ; 13: 386-391
    • (2013) Curr Opin Allergy Clin Immunol , vol.13 , pp. 386-391
    • Wang, J.1
  • 28
    • 0027938207 scopus 로고
    • Ordering S phase and M phase in the cell cycle
    • Nurse P. Ordering S phase and M phase in the cell cycle. Cell. 1994 ; 79: 547-550
    • (1994) Cell , vol.79 , pp. 547-550
    • Nurse, P.1
  • 29
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO. Principles of CDK regulation. Nature. 1995 ; 374: 131-134
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 30
    • 32144460285 scopus 로고    scopus 로고
    • Cyclin D1 and Rb protein expression and their correlation with prognosis in patients with colon cancer
    • Kouraklis G, Theocharis S, Vamvakas P, et al. Cyclin D1 and Rb protein expression and their correlation with prognosis in patients with colon cancer. World J Surg Oncol. 2006 ; 4: 5
    • (2006) World J Surg Oncol , vol.4 , pp. 5
    • Kouraklis, G.1    Theocharis, S.2    Vamvakas, P.3
  • 31
    • 0034884829 scopus 로고    scopus 로고
    • P21/WAF1/Cip1 expression in invasive ductal breast carcinoma: Relationship to p53, proliferation rate, and survival at 5 years
    • Domagala W, Welcker M, Chosia M, et al. p21/WAF1/Cip1 expression in invasive ductal breast carcinoma: relationship to p53, proliferation rate, and survival at 5 years. Virchows Arch. 2001 ; 439: 132-140
    • (2001) Virchows Arch , vol.439 , pp. 132-140
    • Domagala, W.1    Welcker, M.2    Chosia, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.