IRRITANTCY POTENTIAL AND SUB ACUTE DERMAL TOXICITY STUDY OF PISTACIA LENTISCUS FATTY OIL AS A TOPICAL TRADITIONAL REMEDY.

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 10, Issue 3, 2013, Pages 480-489

  Djerrou, Zouhir ^a   Djaalab, Hdria ^a   Riachi, Foulla ^a   Serakta, Mennouba ^a   Chettoum, Aziez ^b   Maameri, Zineb ^a   Boutobza, Badaoui ^c   Hamdi Pacha, Youcef ^a,d  

^a Universite Mentouri Constantine   (Algeria)

^b BADJI MOKHTAR UNIVERSITY   (Algeria)

^c Etablissement Public hospitalier de Tamalous Skikda ^*  (Algeria)

^d l’école Nationale Vétérinaire Supérieure ^*  (Algeria)

Author keywords

dermatitis; eye; fatty oil; irritation; Pistacia lentiscus; skin; toxicity

Indexed keywords

FATTY OIL; VEGETABLE OIL;

ADVERSE EFFECTS; ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; CONTACT DERMATITIS; DERMATITIS; DERMATITIS, CONTACT; DOSE RESPONSE; DRUG EFFECT; DRUG EFFECTS; EYE; EYE DISEASE; EYE DISEASES; FRUIT; GRANULOMA; IRRITATION; LD 50; LD50; MALE; PATHOLOGY; PISTACIA; PISTACIA LENTISCUS; PRODUCT SAFETY; RABBIT; SKIN; TOXICITY; TOXICITY TESTING; TRADITIONAL MEDICINE;

DERMATITIS; EYE; FATTY OIL; IRRITATION; PISTACIA LENTISCUS; SKIN; TOXICITY;

ANALYSIS OF VARIANCE; ANIMALS; CONSUMER PRODUCT SAFETY; DERMATITIS, CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; EYE DISEASES; FRUIT; GRANULOMA; LETHAL DOSE 50; MALE; MEDICINE, TRADITIONAL; PISTACIA; PLANT OILS; RABBITS; SKIN; TOXICITY TESTS;

EID: 84900729062     PISSN: None     EISSN: 25050044     Source Type: Journal    
DOI: 10.4314/ajtcam.v10i3.15     Document Type: Article

References (57)

1. Al-Habbal, M.J., Al-Habbal, Z. and Huwez, F.U. (1984). A double-blind controlled clinical trial of mastic and placebo in the treatment of duodenal ulcer, J. Clin. Exp. Pharmacol. Physiol. 11: 19-23.
2. Amhamdi Hassan, Fatima Aouinti, Jean Paul Wathelet and Ali Elbachiri (2009). Chemical Composition of the Essential Oil of Pistacia lentiscus L. from Eastern Morocco. Rec. Nat. Prod. 3 (2): 90-95.
3. Barra A., V. Coroneo, S. Dessi, P. Cabras, A. Angioni (2007). Characterization of the volatile constituents in the essential oil of Pistacia lentiscus L. from different origins and its antifungal and antioxidant activity. J. Agric. Food Chem. 55: 7093-7098.
4. Benhammou, N., Atik Bekkara, F. and Panovska, T.K. (2008). Antioxidant and antimicrobial activities of the Pistacia lentiscus and atlantica extracts. Afr. J. Pharm. Pharm. 2(2): 22-28.
5. Bentley R.Y. and Trimen H. (1980). Medicinal plants. In Gardeli et al. (Eds) Essential oil composition of Pistacia lentiscus L. and Myrtus communis L.: Evaluation of antioxidant capacity of methanolic extracts. Food Chem. 1-11.
6. Benyoucef, E., Charchari, S., Nacer-Bey, Yahiaoui, N., Chakou, A. and Bellatreche, M. (2005). The essential oil of Pistacia Lentiscus L. from Algeria. J. Essent. Oil Res. 17: 642-644.
7. Bonnier, G., Douin, R. (1990). La Grande Flore. Belin, Paris.
8. Bronaugh, R. L., Stewart, R. F., Storm, J. E. (1989). Extent of cutaneous metabolism during percutaneous absorption of xenobiotics. Toxicol. Appl. Pharmacol. 99: 534-543.
9. Calabro G. and P. Curro (1974). Costituenti degli oli essenziali Nota IV. Essenza di lentisco. Essence Deriv. Agrum. 44: 82-92.
10. Camp, R. D. R. (1982). Prostaglandins, Hydroxy fatty acids, leukotrienes and inflammation of the skin. Clinical and Experimental Dermatology, 7:435 – 444.
11. Castola V., A. Bighelli and J. Casanova (2000). Intraspecic chemical variability of the essential oil of Pistacia lentiscus L. from Corsica. Biochemical Systematics and Ecology. 28: 79-88.
12. Charef, M., Yousfi, M., Saidi, M. and Stoccker, P. (2008). Determination of the fatty acid composition of Acorn (Quercus), Pistacia lentiscus seeds growing in Algeria. J Am Oil Chem Soc. 85: 921-924.
13. Chew A. and Maibach H.I., eds. (2006). Irritant Dermatitis. Germany: Springer.
14. Dabos K.J., E.Sfika,L.J.Vlatta,G. Giannikopoulos (2010). The effect of mastic gum on Helicobacter pylori: A randomized pilot study. Phytomedicine, 17: 296–299.
15. Dedoussis, G.V.Z., Kaliora, A.C., Psarras, S., Chiou, A., Mylona, A., Papadopoulos, N.G. and Andrikopoulos, NK. (2004). Antiatherogenic effect of Pistacia lentiscus via GSH restoration and down regulation of CD36 mRNA expression. Atherosclerosis, 174: 293-303.
16. DeLeo, V. A., Carver, M. P., Hong, J., Fung, K., Kong, B., DeSalva, S. (1995). Arachidonic acid release: an in vitro alternative for dermal irritancy testing. Food and Chemical toxicology, 34 (2): 167 – 176.
17. Djerrou, Z., Maamari, Z., Hamdi-Pacha, Y., Serakta, M., Riachi, F., Djaalab, H. and Boukeloua, A. (2010). Effect of virgin fatty oil of Pistacia lentiscus on experimantal burn wound’s healing in rabbits. Afr. J. Trad. CAM. 7(3): 258-263.
18. Djerrou Z., Y. Hamdi-Pacha, A.M. Belkhiri, H. Djaalab, F. Riachi, M. Serakta, A. Boukeloua, Z. Maameri (2011). Evaluation of Pistacia Lentiscus Fatty Oil Effects on Glycemic Index, Liver Functions and Kidney Functions of New Zealand Rabbits. Afr J Tradit Complement Altern Med. 8(S): 214-219.
19. Dowd, P. M., Greaves, M. W. (1985). Cutaneous responses to lipoxygenase products of arachidonic acid. Acta Dermatologica et Veneorologica (Stokholm) Suppl. 120: 18 – 22.
20. Draize, J., Woodard, G. and Calevery, H. (1944). Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. Journal of pharmacology and Experimental therapeutics, 82:377-390.
21. Duru, M.E., Cakir, A., Kordali, S., Zengin, H., Harmandar, M., Izumi, S. and Hirata, T. (2003). Chemical composition and antifungal properties of essential oils of three Pistacia species. Fitoterapia. 74: 170-176.
22. Dweck, A.C. (2002). Herbal medicine for the skin. Their chemistry and effects on skin and mucous membranes. Personal Care Magazine, 3(2): 19-21.
23. EPA (1998). Health Effects Test Guidelines. OPPTS 870.3200, 21/28-Day Dermal Toxicity.
24. Fernandez A., A. Camacho, C. Fernandez, P. Perez and J. Altarejos (2000). Composition of the essentialoils from galls and aerial parts of Pistacia lentiscus L. J. Essent. Oil Res., 12: 19-23.
25. Isaksson Marlène and Bruze Magnus (1999). Occupational allergic contact dermatitis from olive oil in a masseur. J Am Acad Dermatol., 40: 312-316.
26. Kay, J. H. and Calandra, J. C. (1962). Interpretation of eye irritation tests. Journal of the Society of Cosmetic Chemists, 13:281 – 289.
27. Kivçak B., S. Akay, B. Demirci, K.H.C. Baser (2004). Chemical Composition of Essential Oils from Leaves and Twigs of Pistacia lentiscus var. chia and Pistacia terebinthus from Turkey. Pharm. Biol., 42: 360-366.
28. Kordali, S., Cakir, A., Zengin, H. and Duru, M.E. (2003). Antifungal activities of the leaves of three Pistacia species growth in Turkey. Fitoterapia, 74: 164-167.
29. Kränke B, Komericki P, Aberer W. (1997). Olive oil--contact sensitizer or irritant? Contact Dermatitis, 36(1): 5-10.
30. Lansdown, A.B.G. (1972). An appraisal of methods for detecting primary skin irritants. J. Soc. Cosmet. Chem. 23: 739-772.
31. Lashmar, U. T., Hadgraft, J., Thomas, N. (1989). Topical application of penetration enhancers to the skin of nude mice: a histological study. J. Pharm. Pharmacol. 41: 118 – 121.
32. Le Floc’h, E., & Nabli, M.A. (1983). Programme flore et végétation Tunisiennes. In: Contribution à une étude ethnobotanique de la flore Tunisienne. Tunis. Ministère de l’enseignement supérieur et de la recherche scientifique, imprimerie officielle de la république Tunisienne, 144–145.
33. Margaris, N.S. (1981). Adaptative strategies in plants dominating Mediterranean type ecosystems. In: di Castri, R., Goodall, D.W., Specht, R.I. (Eds.), Ecosystems of the World. Mediterranean type Shrublands, Elsevier Science, 309–315.
34. Mathias CG, Maibach HI, Epstein J. (1978). Allergic contact photodermatitis to para-aminobenzoic acid. Arch Dermatol, 114: 1665 –1666.
35. Mecherara-Idjeri S., A. Hassani, V. Castola, J. Casanova (2008). Composition and chemical variability of the essential oil from Pistacia lentiscus L. growing wild in Algeria Part 1: Leaf oil. J. Essent. oil Res. 20: 32-38.
36. MHLW (Ministry of Health, Labour and Welfare), Japan (2002). Toxicity Testing Reports of Environmental Chemicals, 9: 233-254.
37. Ngo, M. A. and Maibach, H. I. (2010). Dermatotoxicology: historical perspective and advances. Toxicol. Appl. Pharmacol. 243: 225 – 238.
38. OECD (1981). Toxicité cutanée à doses répétées: Etude à 21/28 jours. Ligne directrice 410 pour l’évaluation des produits chimiques.
39. OECD (2002). Acute dermal irritation /corrosion. Method 404. OECD Guidelines for testing of chemicals.
40. OECD (2002). Acute eye irritation/corrosion. Method 405. OECD Guidelines for testing of chemicals.
41. Okuda, M., Yoshiike, T. and Ogawa, H. (2002). Detergent-induced epidermal barrier dysfunction and its prevention. J. Dermatol. Sci. 30: 173-179.
42. Palevitch D, Yaniv Z (2000). Medicinal Plants of the Holy Land. Modan Publishing House, Tel Aviv, Israel. In Ljubuncic et al. (eds) The effects of aqueous extracts prepared from the leaves of Pistacia lentiscus in experimental liver disease. J. Ethnopharmacol, 198 – 204.
43. Patil S, Maibach H.I. (1994). Effect of age and sex on the elicitation of irritant contact dermatitis. Contact Dermatitis, 30: 257 – 264.
44. Pellecuer, J., Jacob, M., Simeon, D.M., Dusart, G., Attisto, M., Barthez, M., Gourgas, L., Pascal, B. and Tomei, R. (1980). Essais d’utilisations d’huiles essentielles de plantes aromatiques Méditerranéennes en odentologie conservatrice. Plant Médicin Phytothér, 14: 83-98.
45. Serpico, M., and White, R. (1998). Chemical analysis of coniferous resins from ancient Egypt using gas chromatography/mass spectrometry (GC/MS), in Proceedings of the Seventh International Congress of Egyptologists, Cambridge, 3–9 September 1995, Orientalia Lovaniensia Analecta, (Peeters: Leuven), 82: 1039 – 1048.
46. Sintov Amnon, Ze’evi Amira, Uza Rina, Nyska Abraham (1999). Influence of pharmaceutical gel vehicles containing oleic acid/ sodium oleate combinations on hairless mouse skin, a histological evaluation. European Journal of Pharmaceutics and biopharmaceutics, 47: 299 – 303.
47. Smeenk, G. (1969). The influence of detergents on the skin (a clinical and biochemical study). Arch. Clin. Exptl. Dermatol. 235:180-185.
48. Takahashi, T., Yokoo, Y., Inoue, T. and Ishil, A. (1999). Toxicological studies on Procyanidin B-2 for external application as a hair growing agent. Food and Chemical Toxicology, 37: 545-552.
49. Tingshuang, Y. I., Jun, W., Avi, G. G., & Dan, E. P. (2008). Phylogenetics and reticulate evolution in Pistacia (Anacardiaceae). American Journal of Botany, 95: 241–251.
50. Tounes, M., Abdennour, C. and Houaine, N. (2008). Influence of Pistacia lentiscus oil on serum biochemical parameters of domestic rabbits Oryctolagus cuniculus in mercury induced toxicity. European Journal of Scientific Research, 24 (4): 591-600.
51. Trabelsi Hajer, Olfa Aicha Cherif, Faouzi Sakouhi, Pierre Villeneuve, Justin Renaud, Nathalie Barouh, Sadok Boukhchina, Paul Mayer (2012). Total lipid content, fatty acids and 4-desmethylsterols accumulation in developing fruit of Pistacia lentiscus L. growing wild in Tunisia. Food Chemistry, 131: 434–440.
52. Ucciani, E. (1995). Nouveau dictionnaire des huiles végétales-Composition en acides gras. Techniques et documentation. Lavoisier, Paris.
53. Vidrich, V., Fusi, P., Graziano, A., Silvestrini, E., Michelozzi, M. and Marco, F. (2004). Chemical composition of the essential oil of Pistacia Lentiscus L. J. Essent. Oil Res. 16: 223-226.
54. Wadaan Mohammad A. M. (2006). Toxicological evaluation of of synthetic detergent-induced effects in rat skin. J. King Saud Univ., 19, Science (1): 1-8.
55. Wright, S. (1989). Essential fatty acids and the skin. Prostaglandins, Lentrienes and Fatty acids: Reviews, 38: 229 – 236.
56. Zhu, J.J., Zeng, X.-P., Berkebile, D., Du, H.-J., Tong, Y. and Qian, K. (2009). Efficacy and safety of catnip (Nepeta Cataria) as a novel filth fly repellent. Medical and Veterinary Entomology, 23: 209-216.
57. Zrira, S., Elamrani, A. and Benjilali, B. (2003). Chemical composition of the essential oil of Pistacia lentiscus L. from Morocco-a seasonal variation. Flavour Fragr. J., 18: 475-480.