PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation

European Journal of Medicinal Chemistry

Volumn 80, Issue , 2014, Pages 562-568

  Perrone, Maria Grazia ^a   Malerba, Paola ^a   Uddin, Md Jashim ^b   Vitale, Paola ^a   Panella, Andrea ^a   Crews, Brenda C ^b   Daniel, Cristina K ^b   Ghebreselasie, Kebreab ^b   Nickels, Mike ^b   Tantawy, Mohammed N ^b   Manning, H Charles ^b   Marnett, Lawrence J ^b   Scilimati, Antonio ^a  

^a UNIVERSITY OF BARI   (Italy)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biomarker; Cyclooxygenase (COX) 1; Ovarian cancer; OVCAR 3 cell; PET CT imaging

Indexed keywords

3 (5 CHLOROFURAN 2 YL) 5 (FLUOROMETHYL) 4 PHENYLISOXAZOLE F 18; CYCLOOXYGENASE 1; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; 3-(5-CHLOROFURAN-2-YL)-4-PHENYL-5-(TRIFLUOROMETHYL)ISOXAZOLE; FLUORINE; FURAN DERIVATIVE; ISOXAZOLE DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR; TRACER; TUMOR MARKER;

ANIMAL EXPERIMENT; ARTICLE; CELL VIABILITY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LEG MUSCLE; MOUSE; NONHUMAN; OVARY ADENOCARCINOMA; PROTEIN EXPRESSION; RADIOCHEMISTRY; THIN LAYER CHROMATOGRAPHY; TUMOR XENOGRAFT; ANIMAL; CELL TRANSFORMATION; CHEMISTRY; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC USE; METABOLISM; OVARY TUMOR; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; RADIOGRAPHY; SCINTISCANNING; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; FEMALE; FLUORINE RADIOISOTOPES; FURANS; HUMANS; ISOXAZOLES; MICE; OVARIAN NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RADIOCHEMISTRY; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 84900565740     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.04.074     Document Type: Article

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