A novel synthesis of N-unsubstituted β-enamino thioesters from 3-arylisoxazoles and 3-aryl-5-phenylthio-2-isoxazolines

Synthesis

Volumn , Issue 18, 2010, Pages 3195-3203

  Vitale, Paola ^a   Di Nunno, Leonardo ^a   Scilimati, Antonio ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

enaminoacyl derivatives; 3 arylisoxazoles; cycloaddition; lithiation; nucleophilic addition

Indexed keywords

-ENAMINOACYL DERIVATIVES; 3-ARYLISOXAZOLES; ISOXAZOLINES; LITHIATION; NUCLEOPHILIC ADDITIONS; PHENYLTHIO; PLAUSIBLE MECHANISMS; THIOESTERS;

ADDITION REACTIONS; AMIDES; ESTERS;

SYNTHESIS (CHEMICAL);

2,2,2 TRIFLUOROETHYL 3 AMINO 3 PHENYLACRYLATE; 3 (2 CHLOROPHENYL) 5 (PHENYLTHIO) 2 ISOXAZOLINE; 3 (4 CHLOROPHENYL) 5 (PHENYLTHIO) 2 ISOXAZOLINE; 3 (4 CHLOROPHENYL)ISOXAZOLINE; 3 (4 ETHOXYPHENYL) 5 (PHENYLTHIO) 2 ISOXAZOLINE; 3 (4 FLUOROPHENYL) 5 (PHENYLTHIO) 2 ISOXAZOLINE; 3 (4 FLUOROROPHENYL)ISOXAZOLINE; 3 (4 TRIFLUOROMETHYLPHENYL)ISOXAZOLINE; 3 ARYL 5 PHENYLTHIO 2 ISOXAZOLINE DERIVATIVE; 3 ARYLISOXAZOLE DERIVATIVE; 3 PHENYL 5 PHENYLTHIO 2 ISOXAZOLINE; 3 PHENYLISOXAZOLE; 4 (PHENYLTHIO) 4 [2 (TRIFLUOROPHENYL)PHENYL]AZETIDIN 2 ONE; 4 (PHENYLTHIO) 4 [4 (TRIFLUOROPHENYL)PHENYL]AZETIDIN 2 ONE; 5 (PHENYLTHIO) 3 [4 (TRIFLUOROMETHYL)PHENYL] 2 ISOXAZOLINE; 5 (PHENYLTHIO) 3 ORTHO TOLYL 2 ISOXAZOLINE; 5 (PHENYLTHIO) 3 PARA TOLYL 2 ISOXAZOLINE; BETA ENAMINO THIOESTER; LITHIUM DERIVATIVE; LITHIUM DIISOPROPYLAMIDE; METHYL 3 AMINO 3 PHENYLACRYLIC ACID; PHENYL 3 AMINO 3 (2 CHLOROPHENYL)PROP 2 ENETHIOIC ACID; PHENYL 3 AMINO 3 (2 TRIFLUOROPHENYL)PROP 2 ENETHIOIC ACID; PHENYL 3 AMINO 3 (4 CHLOROPHENYL)PROP 2 ENETHIOIC ACID; PHENYL 3 AMINO 3 (4 METHOXYLPHENYL)PROP 2 ENETHIOIC ACID; PHENYL 3 AMINO 3 (4 METHYLPHENYL)PROP 2 ENETHIOIC ACID; PHENYL 3 AMINO 3 (4 TRIFLUOROPHENYL)PROP 2 ENETHIOIC ACID; PHENYL 3 AMINO 3 ARYLPROP 2 ENETHIOIC ACID DERIVATIVE; THIOESTER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLOADDITION; LITHIATION; NUCLEOPHILICITY; SYNTHESIS;

EID: 77956488753     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258186     Document Type: Article

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