Contractile dysfunction in a mouse model expressing a heterozygous MYBPC3 mutation associated with hypertrophic cardiomyopathy

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 6, 2014, Pages

  Barefield, David ^a   Kumar, Mohit ^a   de Tombe, Pieter P ^a   Sadayappan, Sakthivel ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Cardiac myosin binding protein C; Haploinsufficiency

Indexed keywords

MYOSIN BINDING PROTEIN C; MYOSIN BINDING PROTEIN C 3; UNCLASSIFIED DRUG; CARRIER PROTEIN; MYOSIN-BINDING PROTEIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LEVEL; CONTRACTILE DYSFUNCTION; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ECHOCARDIOGRAPHY; FUNCTIONAL DISEASE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HEART; HEART FUNCTION; HETEROZYGOTE; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PENETRANCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN PHOSPHORYLATION; SARCOMERE LENGTH; ANIMAL; CARDIAC MYOSIN BINDING PROTEIN-C; DISEASE MODEL; GENETICS; GENOTYPE; HAPLOINSUFFICIENCY; HEART CONTRACTION; HEART MUSCLE CELL; MUTANT MOUSE STRAIN; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; PHOSPHORYLATION; PHYSIOLOGY; SARCOMERE;

CARDIAC MYOSIN BINDING PROTEIN-C; HAPLOINSUFFICIENCY;

ANIMALS; CARDIOMYOPATHY, HYPERTROPHIC; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; GENOTYPE; HETEROZYGOTE; MICE; MICE, MUTANT STRAINS; MUTATION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHENOTYPE; PHOSPHORYLATION; SARCOMERES;

EID: 84900534480     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00913.2013     Document Type: Article

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