Impaired contractile function due to decreased cardiac myosin binding protein C content in the sarcomere

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 1, 2013, Pages

  Cheng, Y ^a   Wan, X ^b   McElfresh, T A ^a   Chen, X ^a   Gresham, K S ^a   Rosenbaum, D S ^b   Chandler, M P ^a   Stelzer, J E ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Cardiomyopathy; Contractile function; Cross bridge kinetics; Myocardium; Myosin binding protein C

Indexed keywords

CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOBUTAMINE; MYOSIN BINDING PROTEIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CARDIOVASCULAR RISK; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; HEART ARRHYTHMIA; HEART CONTRACTION; HEART DISEASE; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE; MALE; MOUSE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QRS COMPLEX; QT INTERVAL; SARCOMERE; STEADY STATE;

CARDIOMYOPATHY; CONTRACTILE FUNCTION; CROSS-BRIDGE KINETICS; MYOCARDIUM; MYOSIN BINDING PROTEIN C;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM SIGNALING; CARRIER PROTEINS; HEART; HEART RATE; HEART VENTRICLES; HETEROZYGOTE; MICE; MUSCLE CONTRACTION; MUTATION; MYOCARDIUM; PHOSPHORYLATION; SARCOMERES; TRANSCRIPTION, GENETIC;

EID: 84879596690     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00929.2012     Document Type: Article

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