Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity

American Journal of Physiology - Endocrinology and Metabolism

Volumn 306, Issue 10, 2014, Pages

  Cao, Jingsong ^a   Perez, Sylvie ^a   Goodwin, Bryan ^a   Lin, Qingcong ^a   Peng, Haibing ^a   Qadri, Ariful ^a   Zhou, Yingjiang ^a   Clark, Ronald W ^a   Perreault, Mylene ^a   Tobin, James F ^a   Gimeno, Ruth E ^a  

^a PFIZER INC   (United States)

Author keywords

Acyltransferase; GPAT; Lipid synthesis; Phospholipid; Triglyceride

Indexed keywords

CHOLESTEROL; GLUCOSE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 3; OXYGEN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DIET; ENERGY; ENERGY EXPENDITURE; ENZYME ACTIVITY; FAT INTAKE; FEMALE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HEPATOMEGALY; HOMEOSTASIS; IN VIVO STUDY; LIPID DIET; LIPID HOMEOSTASIS; LIVER; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN FUNCTION; WEIGHT GAIN; WHITE ADIPOSE TISSUE;

ACYLTRANSFERASE; GPAT; LIPID SYNTHESIS; PHOSPHOLIPID; TRIGLYCERIDE;

ADIPOSE TISSUE, WHITE; ANIMALS; CHOLESTEROL; DIET; ENERGY METABOLISM; FEMALE; GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; HOMEOSTASIS; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY;

EID: 84900533154     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00666.2013     Document Type: Article

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